Xenobiotica, Volume 38, Issue 9 (2008)

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Xenobiotica, Volume 38, Issue 9 (2008)

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Research Article

Article
In vitro metabolism of a novel PPARγ agonist, KR-62980, and its stereoisomer, KR-63198, in human liver microsomes and by recombinant cytochrome P450s
K.-B. Kim, K.-A. Seo, Y.-J. Yoon, M.-A. Bae, H. G. Cheon, J.-G. Shin & K.-H. Liu
Pages: 1165-1176
Published online: 03 May 2008
AbstractforIn vitro metabolism of a novel PPARγ agonist, KR-62980, and its stereoisomer, KR-63198, in human liver microsomes and by recombinant cytochrome P450s | Full Text | References | PDF (130 KB)
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Article
Involvement of stearoyl-CoA desaturase in the reduction of amidoxime prodrugs
R. Reh, J. Ozols & B. Clement
Pages: 1177-1190
Published online: 14 May 2008
AbstractforInvolvement of stearoyl-CoA desaturase in the reduction of amidoxime prodrugs | Full Text | References | PDF (320 KB)
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Article
Characterization of renal tubular apical efflux of zonampanel, an α-amino-3-hydroxy-5- methylisoxazole-4-propionate receptor antagonist, in humans
T. Minematsu, T. Hashimoto, T. Usui & H. Kamimura
Pages: 1191-1202
Published online: 31 May 2008
AbstractforCharacterization of renal tubular apical efflux of zonampanel, an α-amino-3-hydroxy-5- methylisoxazole-4-propionate receptor antagonist, in humans | Full Text | References | PDF (124.9 KB)
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Article
Effect of cationic drugs on the transporting activity of human and rat OCT/Oct 1–3 in vitro and implications for drug–drug interactions
K.-I. Umehara, T. Iwatsubo, K. Noguchi, T. Usui & H. Kamimura
Pages: 1203-1218
Published online: 06 Aug 2008
AbstractforEffect of cationic drugs on the transporting activity of human and rat OCT/Oct 1–3 in vitro and implications for drug–drug interactions | Full Text | References | PDF (147.1 KB)
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Article
Strategies to prevent N-acetyltransferase-mediated metabolism in a series of piperazine-containing pyrazalopyrimidine compounds
J. Rawal, R. Jones, A. Payne & I. Gardner
Pages: 1219-1239
Published online: 11 Aug 2008
AbstractforStrategies to prevent N-acetyltransferase-mediated metabolism in a series of piperazine-containing pyrazalopyrimidine compounds | Full Text | References | PDF (181.4 KB)
  • 195 Views
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Article
Contribution of cytochrome P450 3A4 and 3A5 to the metabolism of atorvastatin
J.-E. Park, K.-B. Kim, S. K. Bae, B.-S. Moon, K.-H. Liu & J.-G. Shin
Pages: 1240-1251
Published online: 12 Aug 2008
AbstractforContribution of cytochrome P450 3A4 and 3A5 to the metabolism of atorvastatin | Full Text | References | PDF (219.6 KB)
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Article
Genetic variants of organic cation transporter 2 (OCT2) significantly reduce metformin uptake in oocytes
I. S. Song, H. J. Shin & J. G. Shin
Pages: 1252-1262
Published online: 16 Oct 2008
AbstractforGenetic variants of organic cation transporter 2 (OCT2) significantly reduce metformin uptake in oocytes | Full Text | References | PDF (98.2 KB)
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