Xenobiotica, Volume 39, Issue 7 (2009)

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Xenobiotica, Volume 39, Issue 7 (2009)

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Research Article

Article
Prediction of animal clearance using naïve Bayesian classification and extended connectivity fingerprints
T. A. McIntyre, C. Han & C. B. Davis
Pages: 487-494
Published online: 29 May 2009
AbstractforPrediction of animal clearance using naïve Bayesian classification and extended connectivity fingerprints | Full Text | References | PDF (788.8 KB)
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Article
Membrane integration of recombinant human P450 forms
A. Shukla, W. Huang, I. M. Depaz & E. M. J. Gillam
Pages: 495-507
Published online: 17 Jun 2009
AbstractforMembrane integration of recombinant human P450 forms | Full Text | References | PDF (976.3 KB)
  • 239 Views
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Article
Effect of sodium tanshinone II A sulfonate on the activity of CYP1A2 in healthy volunteers
Y. Chen, J.-H. Tu, Y.-J. He, W. Zhang, G. Wang, Z.-R. Tan, G. Zhou, L. Fan & H.-H. Zhou
Pages: 508-513
Published online: 12 May 2009
AbstractforEffect of sodium tanshinone II A sulfonate on the activity of CYP1A2 in healthy volunteers | Full Text | References | PDF (751.2 KB)
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Article
Application of multivariate statistical procedures to identify transcription factors that correlate with MRP2, 3, and 4 mRNA in adult human livers
L. M. Aleksunes, R. L. Yeager & C. D. Klaassen
Pages: 514-522
Published online: 29 May 2009
AbstractforApplication of multivariate statistical procedures to identify transcription factors that correlate with MRP2, 3, and 4 mRNA in adult human livers | Full Text | References | PDF (858.4 KB)
  • 146 Views
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Article
Predictability of intranasal pharmacokinetics in man using pre-clinical pharmacokinetic data with a dopamine 3 receptor agonist, PF-219061
N. J. Attkins, A. C. Heatherington, J. Phipps, H. Verrier & I. Huyghe
Pages: 523-533
Published online: 29 May 2009
AbstractforPredictability of intranasal pharmacokinetics in man using pre-clinical pharmacokinetic data with a dopamine 3 receptor agonist, PF-219061 | Full Text | References | PDF (1.6 MB)
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Article
Species differences in the multiple-dose pharmacokinetics of the non-nucleoside reverse transcriptase inhibitor (NNRTI) UK-453,061 in animals and man: implications for safety considerations
D. K. Walker, J. Davis, C. Houle, I. B. Gardner & R. Webster
Pages: 534-543
Published online: 29 May 2009
AbstractforSpecies differences in the multiple-dose pharmacokinetics of the non-nucleoside reverse transcriptase inhibitor (NNRTI) UK-453,061 in animals and man: implications for safety considerations | Full Text | References | PDF (845.4 KB)
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Article
Studies on the pharmacokinetics and metabolism of a γ-secretase inhibitor BMS-299897, and exploratory investigation of CYP enzyme induction
M. Zheng, J. Wang, J. Lubinski, O. P. Flint, R. Krishna, M. Yao, J. M. Pursley, A. Thakur, D. W. Boulton, K. S. Santone, D. M. Barten, J. J. Anderson, K. M. Felsenstein & S. B. Hansel
Pages: 544-555
Published online: 29 May 2009
AbstractforStudies on the pharmacokinetics and metabolism of a γ-secretase inhibitor BMS-299897, and exploratory investigation of CYP enzyme induction | Full Text | References | PDF (840 KB)
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