Xenobiotica, Volume 40, Issue 7 (2010)

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Xenobiotica, Volume 40, Issue 7 (2010)

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General Xenobiochemistry

Article
CYP1B1 expression in rat testis and Leydig cells is not inducible by aryl hydrocarbon receptor agonists
S. Deb, M. Kawai, T.K.H. Chang & S.M. Bandiera
Pages: 447-457
Published online: 23 Apr 2010
AbstractforCYP1B1 expression in rat testis and Leydig cells is not inducible by aryl hydrocarbon receptor agonists | Full Text | References | PDF (739.9 KB)
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Article
In vitro modulation of naturally occurring flavonoids on cytochrome P450 2A6 (CYP2A6) activity
K.H. Tiong, B.C. Yiap, E.L. Tan, R. Ismail & C.E. Ong
Pages: 458-466
Published online: 19 Apr 2010
AbstractforIn vitro modulation of naturally occurring flavonoids on cytochrome P450 2A6 (CYP2A6) activity | Full Text | References | PDF (697 KB)
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Article
Functional characterization of five CYP2C8 variants and prediction of CYP2C8 genotype-dependent effects on in vitro and in vivo drug–drug interactions
Yiwen Gao, Duan Liu, Huijuan Wang, Juanli Zhu & Chao Chen
Pages: 467-475
Published online: 11 May 2010
AbstractforFunctional characterization of five CYP2C8 variants and prediction of CYP2C8 genotype-dependent effects on in vitro and in vivo drug–drug interactions | Full Text | References | PDF (753.3 KB)
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Clinical Pharmacokinetics and Metabolism

Article
Understanding the clinical pharmacokinetics of a GABAA partial agonist by application of in vitro tools
A.D. Sawant, E.L. Miller, D.B. Duignan, J. Brodfuehrer, S.M. Winter, F.R. Nelson, A. Kamel, R.S. Obach & A.D.N. Vaz
Pages: 476-484
Published online: 30 Apr 2010
AbstractforUnderstanding the clinical pharmacokinetics of a GABAA partial agonist by application of in vitro tools | Full Text | References | PDF (863.8 KB)
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Animal Pharmacokinetics and Metabolism

Article
Pharmacokinetics and first-pass effects of ϵ-acetamidocaproic acid after administration of zinc acexamate in rats
Y.H. Choi, U. Lee, J.H. Suh, Y.G. Kim, E.-Y. Choi, E. Oh & M.G. Lee
Pages: 485-498
Published online: 02 Jun 2010
AbstractforPharmacokinetics and first-pass effects of ϵ-acetamidocaproic acid after administration of zinc acexamate in rats | Full Text | References | PDF (794 KB)
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Article
Metabolism and disposition of [14C]dibromoacetonitrile in rats and mice following oral and intravenous administration
J.M. Mathews, D. Pulliam Jr., S.R. Black & L.T. Burka
Pages: 499-509
Published online: 30 Apr 2010
AbstractforMetabolism and disposition of [14C]dibromoacetonitrile in rats and mice following oral and intravenous administration | Full Text | References | PDF (778.4 KB)
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Article
UPLC-MS, HPLC-radiometric, and NMR-spectroscopic studies on the metabolic fate of 3-fluoro-[U-14C]-aniline in the bile-cannulated rat
T. J. Athersuch, J. Castro-Perez, C. Rodgers, J. K. Nicholson & I. D. Wilson
Pages: 510-523
Published online: 05 May 2010
AbstractforUPLC-MS, HPLC-radiometric, and NMR-spectroscopic studies on the metabolic fate of 3-fluoro-[U-14C]-aniline in the bile-cannulated rat | Full Text | References | PDF (1.1 MB)
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