Xenobiotica, Volume 41, Issue 12 (2011)

Browse this journal
Sample our Bioscience journals, sign in here to start your access, Latest two full volumes FREE to you for 14 days

Xenobiotica, Volume 41, Issue 12 (2011)

See all volumes and issues
Vol 54, 2024 Vol 53, 2023 Vol 52, 2022 Vol 51, 2021 Vol 50, 2020 Vol 49, 2019 Vol 48, 2018 Vol 47, 2017 Vol 46, 2016 Vol 45, 2015 Vol 44, 2014 Vol 43, 2013 Vol 42, 2012 Volume 41, 2011 Vol 40, 2010 Vol 39, 2009 Vol 38, 2008 Vol 37, 2007 Vol 36, 2006 Vol 35, 2005 Vol 34, 2004 Vol 33, 2003 Vol 32, 2002 Vol 31, 2001 Vol 30, 2000 Vol 29, 1999 Vol 28, 1998 Vol 27, 1997 Vol 26, 1996 Vol 25, 1995 Vol 24, 1994 Vol 23, 1993 Vol 22, 1992 Vol 21, 1991 Vol 20, 1990 Vol 19, 1989 Vol 18, 1988 Vol 17, 1987 Vol 16, 1986 Vol 15, 1985 Vol 14, 1984 Vol 13, 1983 Vol 12, 1982 Vol 11, 1981 Vol 10, 1980 Vol 9, 1979 Vol 8, 1978 Vol 7, 1977 Vol 6, 1976 Vol 5, 1975 Vol 4, 1974 Vol 3, 1973 Vol 2, 1972 Vol 1, 1971
Download citations Download PDFs Download issue

General Xenobiochemistry

Article
In vitro metabolic interactions between black cohosh (Cimicifuga racemosa) and tamoxifen via inhibition of cytochromes P450 2D6 and 3A4
Jinghu Li, Tanja Gödecke, Shao-Nong Chen, Ayano Imai, David C. Lankin, Norman R. Farnsworth, Guido F. Pauli, Richard B. van Breemen & Dejan Nikolić
Pages: 1021-1030
Published online: 09 Aug 2011
AbstractforIn vitro metabolic interactions between black cohosh (Cimicifuga racemosa) and tamoxifen via inhibition of cytochromes P450 2D6 and 3A4 | Full Text | References | PDF (897.5 KB) | Supplemental
  • 511 Views
  • 23 CrossRef citations
  • 0Altmetric
Article
Species difference in the regulation of cytochrome P450 2S1: lack of induction in rats by the aryl hydrocarbon receptor agonist PCB126
Bingxuan Wang, Larry W. Robertson, Kai Wang & Gabriele Ludewig
Pages: 1031-1043
Published online: 04 Oct 2011
AbstractforSpecies difference in the regulation of cytochrome P450 2S1: lack of induction in rats by the aryl hydrocarbon receptor agonist PCB126 | Full Text | References | PDF (1 MB)
  • 238 Views
  • 13 CrossRef citations
  • 0Altmetric
Article
Flavin monooxygenases, FMO1 and FMO3, not cytochrome P450 isoenzymes, contribute to metabolism of anti-tumour triazoloacridinone, C-1305, in liver microsomes and HepG2 cells
Barbara Fedejko-Kap, Magdalena Niemira, Anna Radominska-Pandya & Zofia Mazerska
Pages: 1044-1055
Published online: 23 Aug 2011
AbstractforFlavin monooxygenases, FMO1 and FMO3, not cytochrome P450 isoenzymes, contribute to metabolism of anti-tumour triazoloacridinone, C-1305, in liver microsomes and HepG2 cells | Full Text | References | PDF (865.1 KB)
  • 349 Views
  • 18 CrossRef citations
  • 0Altmetric
Article
Determination of cytochrome P450 enzymes involved in the metabolism of (−)-terpinen-4-ol by human liver microsomes
M. Miyazawa & R. Haigou
Pages: 1056-1062
Published online: 05 Nov 2011
AbstractforDetermination of cytochrome P450 enzymes involved in the metabolism of (−)-terpinen-4-ol by human liver microsomes | Full Text | References | PDF (794.8 KB)
  • 276 Views
  • 8 CrossRef citations
  • 0Altmetric

Clinical Pharmacokinetics and Metabolism

Article
Disposition, metabolism and mass balance of [14C]apremilast following oral administration
Matthew Hoffmann, Gondi Kumar, Peter Schafer, Dorota Cedzik, Lori Capone, Kei-Lai Fong, Zheming Gu, Dennis Heller, Hao Feng, Sekhar Surapaneni, Oscar Laskin & Anfan Wu
Pages: 1063-1075
Published online: 23 Aug 2011
AbstractforDisposition, metabolism and mass balance of [14C]apremilast following oral administration | Full Text | References | PDF (1 MB)
  • 3507 Views
  • 37 CrossRef citations
  • 0Altmetric
Open Access

Animal Pharmacokinetics and Metabolism

Article
Preclinical assessment of novel BRAF inhibitors: integrating pharmacokinetic-pharmacodynamic modelling in the drug discovery process
Edna F Choo, Bruno Alicke, Jason Boggs, Vikki Dinkel, Stephen Gould, Jonas Grina, Kristina West, Kapil Menghrajani, Yingqing Ran, Joachim Rudolph & Steve Wenglowsky
Pages: 1076-1087
Published online: 25 Aug 2011
AbstractforPreclinical assessment of novel BRAF inhibitors: integrating pharmacokinetic-pharmacodynamic modelling in the drug discovery process | Full Text | References | PDF (960.4 KB)
  • 419 Views
  • 6 CrossRef citations
  • 0Altmetric
Article
Preclinical pharmacokinetics of the novel PI3K inhibitor GDC-0941 and prediction of its pharmacokinetics and efficacy in human
Laurent Salphati, Jodie Pang, Emile G. Plise, Bilin Chou, Jason S. Halladay, Alan G. Olivero, Patrick J. Rudewicz, Qingping Tian, Susan Wong & Xiaolin Zhang
Pages: 1088-1099
Published online: 13 Aug 2011
AbstractforPreclinical pharmacokinetics of the novel PI3K inhibitor GDC-0941 and prediction of its pharmacokinetics and efficacy in human | Full Text | References | PDF (970.4 KB)
  • 764 Views
  • 20 CrossRef citations
  • 0Altmetric
Article
Pharmacokinetics of lurasidone, a novel atypical anti-psychotic drug, in rats
Kyeong-Ryoon Lee, Yoon-Jee Chae & Tae-Sung Koo
Pages: 1100-1107
Published online: 13 Aug 2011
AbstractforPharmacokinetics of lurasidone, a novel atypical anti-psychotic drug, in rats | Full Text | References | PDF (669.4 KB)
  • 696 Views
  • 25 CrossRef citations
  • 0Altmetric

Molecular Toxicology

Article
The fate of 4-hydroxycarbazole metabolite: metabolism and carcinogenicity assessment of a β-adrenergic receptor modulator containing carbazole structure
Minxia M. He, Tao Ji, Robert J. Barbuch, Kristina Campanale, Ron Lantz, Chad Hadden & August Wilke
Pages: 1108-1121
Published online: 05 Sep 2011
AbstractforThe fate of 4-hydroxycarbazole metabolite: metabolism and carcinogenicity assessment of a β-adrenergic receptor modulator containing carbazole structure | Full Text | References | PDF (1.1 MB)
  • 156 Views
  • 1 CrossRef citations
  • 0Altmetric

Pharmacogenetics

Article
Polymorphism in glutathione S-transferases: Susceptibility and treatment outcome for head and neck cancer
Munindra Ruwali, Madhu Singh, Mohan C. Pant & Devendra Parmar
Pages: 1122-1130
Published online: 29 Sep 2011
AbstractforPolymorphism in glutathione S-transferases: Susceptibility and treatment outcome for head and neck cancer | Full Text | References | PDF (662.8 KB)
  • 223 Views
  • 19 CrossRef citations
  • 0Altmetric

Acknowledgements

Acknowledgements
Pages: 1131-1132
Published online: 05 Nov 2011
CitationforAcknowledgements | Full Text | PDF (489.5 KB)
  • 35 Views
  • 0 CrossRef citations
  • 0Altmetric

Explore articles