Cancer Biology & Therapy, Volume 15, Issue 9 (2014)

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Cancer Biology & Therapy, Volume 15, Issue 9 (2014)

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Commentary

Article Commentary
Kindler syndrome in mice and men
Elizabeth K Duperret & Todd W Ridky
Pages: 1113-1116
Published online: 11 Jun 2014
AbstractforKindler syndrome in mice and men | Full Text | References | PDF (588.9 KB)
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Article Commentary
Prolonged low intensity EPOCH–rituximab has improved toxicity in Burkitt lymphoma compared with standard short, high intensity therapy
Shandiz Shahbazi, Cody J Peer & William D Figg
Pages: 1117-1119
Published online: 11 Jun 2014
AbstractforProlonged low intensity EPOCH–rituximab has improved toxicity in Burkitt lymphoma compared with standard short, high intensity therapy | Full Text | References | PDF (570.2 KB)
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Clinical Study

Article
The prognostic significance of combined ERG and androgen receptor expression in patients with prostate cancer managed by androgen deprivation therapy
Kuo-Cheng Huang, Mohammed Alshalalfa, Samar A Hegazy, Michael Dolph, Bryan Donnelly & Tarek A Bismar
Pages: 1120-1128
Published online: 27 Jun 2014
AbstractforThe prognostic significance of combined ERG and androgen receptor expression in patients with prostate cancer managed by androgen deprivation therapy | Full Text | References | PDF (1.4 MB)
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Research Paper

Article
Targeting c-Met in melanoma
Mechanism of resistance and efficacy of novel combinatorial inhibitor therapy
Deven Etnyre, Amanda L Stone, Jason T Fong, Ryan J Jacobs, Srijayaprakash B Uppada, Gregory M Botting, Supriya Rajanna, David N Moravec, Manohar R Shambannagari, Zachary Crees, Jennifer Girard, Ceyda Bertram & Neelu Puri
Pages: 1129-1141
Published online: 11 Jun 2014
AbstractforTargeting c-Met in melanoma | Full Text | References | PDF (2.5 MB) | Supplemental
  • 2211 Views
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Article
Carfilzomib and oprozomib synergize with histone deacetylase inhibitors in head and neck squamous cell carcinoma models of acquired resistance to proteasome inhibitors
Yan Zang, Christopher J Kirk & Daniel E Johnson
Pages: 1142-1152
Published online: 10 Jun 2014
AbstractforCarfilzomib and oprozomib synergize with histone deacetylase inhibitors in head and neck squamous cell carcinoma models of acquired resistance to proteasome inhibitors | Full Text | References | PDF (1.9 MB) | Supplemental
  • 1184 Views
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Article
Inhibition of STAT3 activity re-activates anti-tumor immunity but fails to restore the immunogenicity of tumor cells in a B-cell lymphoma model
Yang Cao, Xiaoxi Zhou, Mi Zhou, Danmei Xu, Quanfu Ma, Peilin Zhang, Xiaoyuan Huang, Qinlu Li, Ding Ma & Jianfeng Zhou
Pages: 1153-1162
Published online: 10 Jun 2014
AbstractforInhibition of STAT3 activity re-activates anti-tumor immunity but fails to restore the immunogenicity of tumor cells in a B-cell lymphoma model | Full Text | References | PDF (2.4 MB) | Supplemental
  • 841 Views
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Article
Coronin3 regulates gastric cancer invasion and metastasis by interacting with Arp2
Yi Sun, Yulong Shang, Gui Ren, Lin Zhou, Bin Feng, Kai Li, Lin Deng, Jie Liang, Yuanyuan Lu & Xin Wang
Pages: 1163-1173
Published online: 11 Jun 2014
AbstractforCoronin3 regulates gastric cancer invasion and metastasis by interacting with Arp2 | PDF (4.7 MB) | Supplemental
  • 283 Views
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Article
QKI impairs self-renewal and tumorigenicity of oral cancer cells via repression of SOX2
Wei Lu, Feixue Feng, Jinke Xu, Xiaozhao Lu, Shan Wang, Lifeng Wang, Huanyu Lu, Mengying Wei, Guodong Yang, Li Wang, Zifan Lu, Yanpu Liu & Xiaoying Lei
Pages: 1174-1184
Published online: 11 Jun 2014
AbstractforQKI impairs self-renewal and tumorigenicity of oral cancer cells via repression of SOX2 | Full Text | References | PDF (2.4 MB) | Supplemental
  • 1107 Views
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Article
Riproximin’s activity depends on gene expression and sensitizes PDAC cells to TRAIL
Hassan Adwan, Ahmed Murtaja, Khamael Kadhim Al-Taee, Asim Pervaiz, Thomas Hielscher & Martin R Berger
Pages: 1185-1197
Published online: 11 Jun 2014
AbstractforRiproximin’s activity depends on gene expression and sensitizes PDAC cells to TRAIL | Full Text | References | PDF (1.5 MB) | Supplemental
  • 679 Views
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Article
The interplay between histone deacetylases and c-Myc in the transcriptional suppression of HPP1 in colon cancer
Jian Wang, Abul Elahi, Abidemi Ajidahun, Whalen Clark, Jonathan Hernandez, Alex Achille, Ji-hui Hao, Edward Seto & David Shibata
Pages: 1198-1207
Published online: 11 Jun 2014
AbstractforThe interplay between histone deacetylases and c-Myc in the transcriptional suppression of HPP1 in colon cancer | Full Text | References | PDF (2.5 MB)
  • 1038 Views
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Article
A human monoclonal antibody targeting the stem cell factor receptor (c-Kit) blocks tumor cell signaling and inhibits tumor growth
Maria B Lebron, Laura Brennan, Christopher B Damoci, Marie C Prewett, Marguerita O’Mahony, Inga J Duignan, Kelly M Credille, James T DeLigio, Marina Starodubtseva, Michael Amatulli, Yiwei Zhang, Kaben D Schwartz, Douglas Burtrum, Paul Balderes, Kris Persaud, David Surguladze, Nick Loizos, Keren Paz & Helen Kotanides
Pages: 1208-1218
Published online: 12 Jun 2014
AbstractforA human monoclonal antibody targeting the stem cell factor receptor (c-Kit) blocks tumor cell signaling and inhibits tumor growth | Full Text | References | PDF (1.5 MB) | Supplemental
  • 1610 Views
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Article
Sulforaphane induces apoptosis in rhabdomyosarcoma and restores TRAIL-sensitivity in the aggressive alveolar subtype leading to tumor elimination in mice
Elisa Bergantin, Carmelo Quarta, Cristina Nanni, Stefano Fanti, Andrea Pession, Giorgio Cantelli-Forti, Roberto Tonelli & Patrizia Hrelia
Pages: 1219-1225
Published online: 27 Jun 2014
AbstractforSulforaphane induces apoptosis in rhabdomyosarcoma and restores TRAIL-sensitivity in the aggressive alveolar subtype leading to tumor elimination in mice | Full Text | References | PDF (1.6 MB) | Supplemental
  • 876 Views
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Article
Genetically engineered Newcastle disease virus expressing interleukin-2 and TNF-related apoptosis-inducing ligand for cancer therapy
Fu-Liang Bai, Yin-Hang Yu, Hui Tian, Gui-Ping Ren, Hui Wang, Bing Zhou, Xiao-Hui Han, Qing-Zhong Yu & De-Shan Li
Pages: 1226-1238
Published online: 27 Jun 2014
AbstractforGenetically engineered Newcastle disease virus expressing interleukin-2 and TNF-related apoptosis-inducing ligand for cancer therapy | Full Text | References | PDF (4.4 MB)
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Article
Impact of ERBB2 mutations on in vitro sensitivity of bladder cancer to lapatinib
Michela de Martino, Dazhong Zhuang, Tobias Klatte, Malte Rieken, Morgan Rouprêt, Evanguelos Xylinas, Thomas Clozel, Martin Krzywinski, Olivier Elemento & Shahrokh F Shariat
Pages: 1239-1247
Published online: 14 Jul 2014
AbstractforImpact of ERBB2 mutations on in vitro sensitivity of bladder cancer to lapatinib | Full Text | References | PDF (2.6 MB)
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Article
Expression profiling of serum microRNA-101 in HBV-associated chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma
Yun Xie, Qinwei Yao, Azeem Mehmood Butt, Jia Guo, Zhou Tian, Xuli Bao, Hongxia Li, Qinghua Meng & Jun Lu
Pages: 1248-1255
Published online: 27 Jun 2014
AbstractforExpression profiling of serum microRNA-101 in HBV-associated chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma | Full Text | References | PDF (1,013.9 KB) | Supplemental
  • 1357 Views
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Article
Indole-3-carbinol (I3C) increases apoptosis, represses growth of cancer cells, and enhances adenovirus-mediated oncolysis
Lan Chen, Pei-Hsin Cheng, Xiao-Mei Rao, Kelly M McMasters & Heshan Sam Zhou
Pages: 1256-1267
Published online: 27 Jun 2014
AbstractforIndole-3-carbinol (I3C) increases apoptosis, represses growth of cancer cells, and enhances adenovirus-mediated oncolysis | Full Text | References | PDF (2.7 MB)
  • 1289 Views
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Article
Chk1-induced CCNB1 overexpression promotes cell proliferation and tumor growth in human colorectal cancer
Yifeng Fang, Hong Yu, Xiao Liang, Junfen Xu & Xiujun Cai
Pages: 1268-1279
Published online: 27 Jun 2014
AbstractforChk1-induced CCNB1 overexpression promotes cell proliferation and tumor growth in human colorectal cancer | Full Text | References | PDF (3.7 MB)
  • 2117 Views
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Article
An improved isoprenylcysteine carboxylmethyltransferase inhibitor induces cancer cell death and attenuates tumor growth in vivo
Hiu Yeung Lau, Pondy M Ramanujulu, Dianyan Guo, Tianming Yang, Melissa Wirawan, Patrick J Casey, Mei-Lin Go & Mei Wang
Pages: 1280-1291
Published online: 27 Jun 2014
AbstractforAn improved isoprenylcysteine carboxylmethyltransferase inhibitor induces cancer cell death and attenuates tumor growth in vivo | Full Text | References | PDF (2.5 MB)
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