Cancer Biology & Therapy, Volume 2, Issue 4 (2003)

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Cancer Biology & Therapy, Volume 2, Issue 4 (2003)

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Editor's Corner

Editorial
Cover Image
Page: i
Published online: 20 Mar 2003
AbstractforCover Image | PDF (6.1 MB)
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Editorial
Letter to the Editorial Board
Wafik S. El-Deiry
Page: 309
Published online: 20 Mar 2003
AbstractforLetter to the Editorial Board | PDF (43.9 KB)
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Review

Review Article
Signal Transduction and Myeloma: New Targets, New Hope
Sagar Lonial, Edmund K Waller, Jonathan W. Simons & L.T. Heffner Jr.
Pages: 310-319
Published online: 20 Mar 2003
AbstractforSignal Transduction and Myeloma: New Targets, New Hope | PDF (364.3 KB)
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Review Article
EpCAM: A New Therapeutic Target for an Old Cancer Antigen
Andrew Armstrong & Stephen L. Eck
Pages: 320-325
Published online: 20 Mar 2003
AbstractforEpCAM: A New Therapeutic Target for an Old Cancer Antigen | PDF (206.2 KB)
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Review Article
Radiation Therapy—Activation of Gene Transcription and the Development of Genetic Radiotherapy: Therapeutic Strategies in Oncology
Donald Kufe & Ralph Weichselbaum
Pages: 326-329
Published online: 20 Mar 2003
AbstractforRadiation Therapy—Activation of Gene Transcription and the Development of Genetic Radiotherapy: Therapeutic Strategies in Oncology | PDF (123.9 KB)
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Review Article
Receptor Tyrosine Kinase Signaling In Gliomagenesis: Pathobiology And Therapeutic Approaches
Gurpreet S. Kapoor & Donald M. O’Rourke
Pages: 330-342
Published online: 20 Mar 2003
AbstractforReceptor Tyrosine Kinase Signaling In Gliomagenesis: Pathobiology And Therapeutic Approaches | PDF (357.3 KB)
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Exegeses and Views

A Model of Self-Maintenance of In Vivo Malignant Growth Not Dependent on Tumour Type or Origin: Syndrome of Everlasting Wound Healing
Andrey N. Luchnik
Pages: 343-346
Published online: 20 Mar 2003
AbstractforA Model of Self-Maintenance of In Vivo Malignant Growth Not Dependent on Tumour Type or Origin: Syndrome of Everlasting Wound Healing | PDF (139.7 KB)
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Research Paper

Article
mda-7 (IL-24) Inhibits Growth and Enhances Radiosensitivity of Glioma Cells In Vitro via JNK Signaling
Adly Yacoub, Clint Mitchell, Irina V. Lebedeva, Devanand Sarkar, Zao-Zhong Su, Robert McKinstry, Rahul V. Gopalkrishnan, Steven Grant, Paul B. Fisher & Paul Dent
Pages: 347-353
Published online: 20 Mar 2003
Abstractformda-7 (IL-24) Inhibits Growth and Enhances Radiosensitivity of Glioma Cells In Vitro via JNK Signaling | PDF (314.7 KB)
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Commentary

A New Hope for Treatment of Glioblastomas
Oswaldo Rodriguez-Mora, Richard A. Franklin & James A McCubrey
Pages: 354-355
Published online: 20 Mar 2003
AbstractforA New Hope for Treatment of Glioblastomas | PDF (58 KB)
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Research Paper

Article
Evaluation of Anti-tumor property of Specific and Non-specific BRMs in Experimental Glioma by Assessing the Microglial Cell Functional and Phenotypic Modulations
Z. Begum, Susobhan Sarkar, Joydeep Mukherjee, Anirban Ghosh, Samares Chaudhuri & Swapna Chaudhuri
Pages: 356-363
Published online: 20 Mar 2003
AbstractforEvaluation of Anti-tumor property of Specific and Non-specific BRMs in Experimental Glioma by Assessing the Microglial Cell Functional and Phenotypic Modulations | PDF (389 KB)
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Article
A Novel Function for the rTS gene
Bruce J. Dolnick, Norman J. Angelino, Ree Dolnick & Janice R. Sufrin
Pages: 364-369
Published online: 20 Mar 2003
AbstractforA Novel Function for the rTS gene | PDF (288.5 KB)
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Commentary

A Novel Methionine-Based Signaling Mechanism Regulating the Expression of Thymidylate Synthase
Edward Chu
Pages: 370-371
Published online: 20 Mar 2003
AbstractforA Novel Methionine-Based Signaling Mechanism Regulating the Expression of Thymidylate Synthase | PDF (46.5 KB)
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Research Paper

Article
Repression of IR-Inducible Clusterin Expression by the p53 Tumor Suppressor Protein
Tracy Criswell, Dmitry Klokov, Meghan Beman, JP Lavik & David A. Boothman
Pages: 372-380
Published online: 20 Mar 2003
AbstractforRepression of IR-Inducible Clusterin Expression by the p53 Tumor Suppressor Protein | PDF (731.8 KB)
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Commentary

The Thousand Doors that Lead to Death: p53-Dependent Repression and Apoptosis
Maureen Murphy
Pages: 381-382
Published online: 20 Mar 2003
AbstractforThe Thousand Doors that Lead to Death: p53-Dependent Repression and Apoptosis | PDF (47.8 KB)
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Research Paper

Article
MicroArray Data Simulator For Improved Selection of Differentially Expressed Genes
Sunil Singhal, Chris G. Kyvernitis, Steven W. Johnson, Larry R. Kaiser, Michael N. Liebman & Steven M. Albelda
Pages: 383-391
Published online: 20 Mar 2003
AbstractforMicroArray Data Simulator For Improved Selection of Differentially Expressed Genes | PDF (406.5 KB)
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Article
CD95 Rapidly Clusters in Cells of Diverse Origins
Jessica C. Fanzo, Maureen P. Lynch, Hyewon Phee, Marc Hyer, Aida Cremesti, Heike Grassmé, James S. Norris, K. Mark Coggeshall, Bo R. Rueda, Alessandra B. Pernis, Richard Kolesnick & Erich Gulbins
Pages: 392-395
Published online: 20 Mar 2003
AbstractforCD95 Rapidly Clusters in Cells of Diverse Origins | PDF (384 KB)
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Commentary

A Life-Raft for Death Signalling?
Dagmar Scheel-Toellner, Mike Salmon & Janet M. Lord
Pages: 396-397
Published online: 20 Mar 2003
AbstractforA Life-Raft for Death Signalling? | PDF (52.4 KB)
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Research Paper

Article
Maspin Regulates Different Signaling Pathways for Motility and Adhesion in Aggressive Breast Cancer Cells
Valerie A. Odero-Marah, Zhila Khalkhali-Ellis, Jirapat Chunthapong, Sumaira Amir, Richard E.B. Seftor, Elisabeth A Seftor & Mary J.C. Hendrix
Pages: 398-403
Published online: 20 Mar 2003
AbstractforMaspin Regulates Different Signaling Pathways for Motility and Adhesion in Aggressive Breast Cancer Cells | PDF (472.2 KB)
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Commentary

Maspin and the Order of Signaling
Shijie Sheng
Pages: 404-405
Published online: 20 Mar 2003
AbstractforMaspin and the Order of Signaling | PDF (41.3 KB)
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Research Paper

Article
Global Genechip Profiling to Identify Genes Responsive to p53-Induced Growth Arrest and Apoptosis in Human Lung Carcinoma Cells
Megan Robinson, Ping Jiang, Jenny Cui, Jun Li, Yuli Wang, Manju Swaroop, Steve Madore, Theodore S. Lawrence & Yi Sun
Pages: 406-415
Published online: 20 Mar 2003
AbstractforGlobal Genechip Profiling to Identify Genes Responsive to p53-Induced Growth Arrest and Apoptosis in Human Lung Carcinoma Cells | PDF (323.8 KB)
  • 241 Views
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Article
Microarray Expression Profiling of p53-Dependent Transcriptional Changes in an Immortalized Mouse Embryo Fibroblast Cell Line
Joanna K. Sax, Alex Stoddard, Maureen E. Murphy, Lewis Chodosh & Wafik S. El-Deiry
Pages: 416-430
Published online: 20 Mar 2003
AbstractforMicroarray Expression Profiling of p53-Dependent Transcriptional Changes in an Immortalized Mouse Embryo Fibroblast Cell Line | PDF (200.3 KB)
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Article
Microarray Analysis of p53 Target Gene Expression Patterns in the Spleen and Thymus in Response to Ionizing Radiation
Timothy F Burns & Wafik S. El-Deiry
Pages: 431-443
Published online: 20 Mar 2003
AbstractforMicroarray Analysis of p53 Target Gene Expression Patterns in the Spleen and Thymus in Response to Ionizing Radiation | PDF (1.4 MB)
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Commentary

Microarray Analysis of p53-Mediated Transcription: Mutli-Thousand Piece Puzzle or Invitation to Collective Thinking?
Andrei Gudkov
Pages: 444-445
Published online: 20 Mar 2003
AbstractforMicroarray Analysis of p53-Mediated Transcription: Mutli-Thousand Piece Puzzle or Invitation to Collective Thinking? | PDF (45.4 KB)
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Research Paper

Article
LETAL, A Tumor-Associated NKG2D Immunoreceptor Ligand, Induces Activation and Expansion of Effector Immune Cells
José R. Conejo-Garcia, Fabian Benencia, Maria C. Courrèges, Eugene Khang, Lin Zhang, Alisha Mohamed-Hadley, Jeffrey M. Vinocur, Ronald J. Buckanovich, Craig B. Thompson, Bruce Levine & George Coukos
Pages: 446-451
Published online: 20 Mar 2003
AbstractforLETAL, A Tumor-Associated NKG2D Immunoreceptor Ligand, Induces Activation and Expansion of Effector Immune Cells | PDF (285.5 KB)
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Research Philosophy

Editorial
New Paradigms for Cancer Drug Discovery?
Jason A. Sager & Christoph Lengauer
Pages: 452-455
Published online: 20 Mar 2003
AbstractforNew Paradigms for Cancer Drug Discovery? | PDF (58.1 KB)
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Profiles in Science

Editorial
From Bings to Biology: Taking a Different Path in Cancer Research
Tom Curran
Pages: 456-459
Published online: 20 Mar 2003
AbstractforFrom Bings to Biology: Taking a Different Path in Cancer Research | PDF (102.6 KB)
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Book Review

Book Review
The Role of Telomeres and Telomerase in Human Cancer
Oliver G. Opitz
Pages: 460-461
Published online: 20 Mar 2003
AbstractforThe Role of Telomeres and Telomerase in Human Cancer | PDF (61.8 KB)
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