Cancer Biology & Therapy, Volume 4, Issue 1 (2005)

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Cancer Biology & Therapy, Volume 4, Issue 1 (2005)

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Editor's Corner

Editorial
Cover Image
Page: i
Published online: 28 Dec 2004
AbstractforCover Image | PDF (1.2 MB)
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Editorial
Letter to the Editorial Board of Cancer Biology and Therapy
Wafik S. El-Deiry
Page: 3
Published online: 20 Dec 2004
AbstractforLetter to the Editorial Board of Cancer Biology and Therapy | PDF (131.6 KB)
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Editorial
Letter to the Editor: Androgens and Prostate Cancer: Are the Descriptors Valid?
Pradip Roy-Burman, Donald J. Tindall, Diane M. Robins, Norman M. Greenberg, Mary J.C. Hendrix, Suresh Mohla, Robert H. Getzenberg, John T. Isaacs & Kenneth J. Pienta
Pages: 4-5
Published online: 28 Jan 2005
AbstractforLetter to the Editor: Androgens and Prostate Cancer: Are the Descriptors Valid? | PDF (134.7 KB)
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News

News
BRAF and COX-2 as Targets for Therapy of Thyroid Cancer
na
Pages: 6-12
Published online: 10 Dec 2004
AbstractforBRAF and COX-2 as Targets for Therapy of Thyroid Cancer | PDF (94.2 KB)
  • 132 Views
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News
Chronic Stress and Cancer Risk
na
Pages: 6-12
Published online: 10 Dec 2004
AbstractforChronic Stress and Cancer Risk | PDF (94.2 KB)
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News
Celebrex Triggers Death Receptors in Non-Small Cell Lung Cancer
na
Pages: 6-12
Published online: 13 Dec 2004
AbstractforCelebrex Triggers Death Receptors in Non-Small Cell Lung Cancer | PDF (94.2 KB)
  • 110 Views
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News
Head and Neck Cancer Biomarkers Detected in Saliva
na
Pages: 6-12
Published online: 20 Dec 2004
AbstractforHead and Neck Cancer Biomarkers Detected in Saliva | PDF (94.2 KB)
  • 127 Views
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News
Stem Cells Attracted by Tissue Inflammation
na
Pages: 6-12
Published online: 20 Dec 2004
AbstractforStem Cells Attracted by Tissue Inflammation | PDF (94.2 KB)
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News
Myeloid Progenitors Improve Survival of 5-FU-Treated Mice
na
Pages: 6-12
Published online: 20 Dec 2004
AbstractforMyeloid Progenitors Improve Survival of 5-FU-Treated Mice | PDF (94.2 KB)
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News
Protein Phophorylation Mechanism Involving IP7 Instead of ATP Holds Clues for New Drugs
na
Pages: 6-12
Published online: 20 Dec 2004
AbstractforProtein Phophorylation Mechanism Involving IP7 Instead of ATP Holds Clues for New Drugs | PDF (94.2 KB)
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News
CCI-779 Effectively Targets mTOR in Prostate Tumors with Common PTEN Mutations
na
Pages: 6-12
Published online: 27 Dec 2004
AbstractforCCI-779 Effectively Targets mTOR in Prostate Tumors with Common PTEN Mutations | PDF (94.2 KB)
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News
Differential Response to IL-4 Offers Clues to Therapy of Diffuse Lymphoma Subtypes
na
Pages: 6-12
Published online: 27 Dec 2004
AbstractforDifferential Response to IL-4 Offers Clues to Therapy of Diffuse Lymphoma Subtypes | PDF (94.2 KB)
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Review

Review Article
The thioredoxin reductase/thioredoxin system: Novel redox targets for cancer therapy
John E. Biaglow & Richard A. Miller
Pages: 13-20
Published online: 16 Nov 2004
AbstractforThe thioredoxin reductase/thioredoxin system: Novel redox targets for cancer therapy | PDF (451.1 KB)
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Review Article
The SERCA pump as a therapeutic target: Making a “smart bomb” for prostate cancer
Samuel R. Denmeade & John T. Isaacs
Pages: 21-29
Published online: 16 Nov 2004
AbstractforThe SERCA pump as a therapeutic target: Making a “smart bomb” for prostate cancer | PDF (448.2 KB)
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Bedside to Bench Report

Article
Paraneoplastic leukemoid reaction and rapid progression in a patient with malignant melanoma: Establishment of KT293, A novel G-CSF-secreting melanoma cell line
Bodo Schniewind, Matthias Christgen, Axel Hauschild, Roland Kurdow, Holger Kalthoff & Hans Jürgen Klomp
Pages: 30-34
Published online: 16 Nov 2004
AbstractforParaneoplastic leukemoid reaction and rapid progression in a patient with malignant melanoma: Establishment of KT293, A novel G-CSF-secreting melanoma cell line | PDF (498 KB)
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Journal Club

No one-way street: Cross-talk between E-cadherin and receptor tyrosine kinase (RTK) signaling—A mechanism to regulate RTK activity
Claudia D. Andl & Anil K. Rustgi
Pages: 35-38
Published online: 16 Nov 2004
AbstractforNo one-way street: Cross-talk between E-cadherin and receptor tyrosine kinase (RTK) signaling—A mechanism to regulate RTK activity | PDF (441.4 KB)
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Research Paper

Article
Prognostic role of bcl-xL and p53 in childhood acute lymphoblastic leukemia
Raffaele Addeo, Michele Caraglia, Alfonso Baldi, Velia D’Angelo, Fiorina Casale, Stefania Crisci, Alberto Abbruzzese, Bruno Vincenzi, Mara Campioni, Maria Teresa Di Tullio & Paolo Indolfi
Pages: 39-45
Published online: 16 Nov 2004
AbstractforPrognostic role of bcl-xL and p53 in childhood acute lymphoblastic leukemia | PDF (782.5 KB)
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Article
The tumor suppressor p33ING1b enhances taxol-induced apoptosis by p53-dependent pathway in human osteosarcoma U2OS cells
Jin-Jun Zhu, Fo-Bao Li, Jun-Min Zhou, Zong-Chao Liu, Xiao-Feng Zhu & Wei-Ming Liao
Pages: 46-54
Published online: 16 Nov 2004
AbstractforThe tumor suppressor p33ING1b enhances taxol-induced apoptosis by p53-dependent pathway in human osteosarcoma U2OS cells | PDF (781.6 KB)
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Commentary

An intact ING1-p53 pathway can potentiate the cytotoxic effects of taxol
Igor Garkavtsev & Yves Boucher
Pages: 55-56
Published online: 16 Nov 2004
AbstractforAn intact ING1-p53 pathway can potentiate the cytotoxic effects of taxol | PDF (175.2 KB)
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Research Paper

Article
Unpulsed dendritic cells induce broadly applicable anti-tumor immunity in mice
Grzegorz Dworacki, Vito R. Cicinnati, Susanne Beckebaum, Eva Pizzoferrato, Thomas K. Hoffmann & Albert B. De Leo
Pages: 57-63
Published online: 16 Nov 2004
AbstractforUnpulsed dendritic cells induce broadly applicable anti-tumor immunity in mice | PDF (416 KB)
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Article
The relationships between p53 protein expression and the clinicopathological features in the uveal melanomas
Mahmoud R. Hussein
Pages: 64-66
Published online: 16 Nov 2004
AbstractforThe relationships between p53 protein expression and the clinicopathological features in the uveal melanomas | PDF (546.8 KB)
  • 313 Views
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Article
ZNRD1 gene suppresses cell proliferation through cell cycle arrest in G1 phase
Liu Hong, Yu Han, Rui Shi, Xiaodong Shao, Lijun Sun, Yumei Zhang, Dawei Huang, Zhen Chen, Guoyun Zhang, Jie Liang & Daiming Fan
Pages: 67-71
Published online: 16 Nov 2004
AbstractforZNRD1 gene suppresses cell proliferation through cell cycle arrest in G1 phase | PDF (552.7 KB)
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Article
Effects of HIV-1 Nef, a cytotoxic viral protein, on the growth of primary colorectal cancer
Harvey L. Bumpers, Ming-Bo Huang, Michael Powell, William E. Grizzle, James Lillard, Joel Okoli & Vincent C. Bond
Pages: 72-76
Published online: 16 Nov 2004
AbstractforEffects of HIV-1 Nef, a cytotoxic viral protein, on the growth of primary colorectal cancer | PDF (406.4 KB)
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Article
The Chemokine Receptor CXCR4 is Regulated by DNA Methylation in Pancreatic Cancer
Norihiro Sato, Hiroyuki Matsubayashi, Noriyoshi Fukushima & Michael Goggins
Pages: 77-83
Published online: 16 Nov 2004
AbstractforThe Chemokine Receptor CXCR4 is Regulated by DNA Methylation in Pancreatic Cancer | PDF (513 KB)
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Article
The proteasome inhibitor bortezomib (PS-341) inhibits growth and induces apoptosis in primary effusion lymphoma cells
Hittu Matta & Preet M. Chaudhary
Pages: 84-89
Published online: 16 Nov 2004
AbstractforThe proteasome inhibitor bortezomib (PS-341) inhibits growth and induces apoptosis in primary effusion lymphoma cells | PDF (515.4 KB)
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Article
Homozygous deletion of the MTAP gene in invasive adenocarcinoma of the pancreas and in periampullary cancer: A potential new target for therapy
Steven R. Hustinx, Ralph H. Hruban, Lorenzo M. Leoni, Christine Iacobuzio-Donahue, John L. Cameron, Charles J. Yeo, Priscilla N. Brown, Pedram Argani, Raheela Ashfaq, Noriyoshi Fukushima, Michael Goggins, Scott E. Kern & Anirban Maitra
Pages: 90-93
Published online: 16 Nov 2004
AbstractforHomozygous deletion of the MTAP gene in invasive adenocarcinoma of the pancreas and in periampullary cancer: A potential new target for therapy | PDF (456.8 KB)
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Article
The glycolytic inhibitor 2-deoxy-D-glucose enhances the efficacy of etoposide in ehrlich ascites tumor bearing mice
Seema Gupta, Rohit Mathur & B. Dwarakanath
Pages: 94-101
Published online: 16 Nov 2004
AbstractforThe glycolytic inhibitor 2-deoxy-D-glucose enhances the efficacy of etoposide in ehrlich ascites tumor bearing mice | PDF (442.1 KB)
  • 796 Views
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Article
Efficacy of beta-lapachone in pancreatic cancer treatment: Exploiting the novel, therapeutic target NQO1
Matthew Ough, Anne Lewis, Erik A. Bey, Jinming Gao, Justine M. Ritchie, William Bornmann, David A. Boothman, Larry W. Oberley & Joseph J. Cullen
Pages: 102-109
Published online: 16 Nov 2004
AbstractforEfficacy of beta-lapachone in pancreatic cancer treatment: Exploiting the novel, therapeutic target NQO1 | PDF (740.9 KB)
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Article
Defining the extent of cables loss in endometrial cancer subtypes and its effectiveness as an inhibitor of cell proliferation in malignant endometrial cells in vitro and in vivo
Robert L. Debernardo, Ramey D. Littell, Hongweit Luo, Linda R. Duska, Esther Oliva, Sandra D. Kirley, Maureen P. Lynch, Lawrence R. Zukerberg & Bo Rueda
Pages: 110-114
Published online: 16 Nov 2004
AbstractforDefining the extent of cables loss in endometrial cancer subtypes and its effectiveness as an inhibitor of cell proliferation in malignant endometrial cells in vitro and in vivo | PDF (575.2 KB)
  • 286 Views
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Article
DNA ploidy and S phase fraction of breast and ovarian tumor cells treated with a natural anthracycline analog (Aloin)
Amr Y. Esmat, Shadia M. El-Gerzawy & Amira Rafaat
Pages: 115-119
Published online: 16 Nov 2004
AbstractforDNA ploidy and S phase fraction of breast and ovarian tumor cells treated with a natural anthracycline analog (Aloin) | PDF (369.6 KB)
  • 358 Views
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Article
Inhibition of gastric cancer angiogenesis by vector-based RNA interference for Raf-1
Fanping Meng, Jie Ding, Na Liu, Jing Zhang, Xiaodong Shao, Huiqin Shen, Yan Xue, Huahong Xie & Daiming Fan
Pages: 120-124
Published online: 16 Nov 2004
AbstractforInhibition of gastric cancer angiogenesis by vector-based RNA interference for Raf-1 | PDF (824.6 KB)
  • 398 Views
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Article
Antitumor effect of valorphin in vitro and in vivo: Combined action with cytostatic drugs
Elena Yu. Blishchenko, Olga V. Sazonova, Olga A. Kalinina, Ekaterina V. Moiseeva, Arpad A. Vass, Andrey A. Karelin & Vadim T. Ivanov
Pages: 125-131
Published online: 16 Nov 2004
AbstractforAntitumor effect of valorphin in vitro and in vivo: Combined action with cytostatic drugs | PDF (358.6 KB)
  • 260 Views
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Profiles and Legacies

Editorial
Was Warburg right? Or was it that simple?
Britton Chance
Pages: 132-133
Published online: 16 Nov 2004
AbstractforWas Warburg right? Or was it that simple? | PDF (348.3 KB)
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Book Review

Book Review
Marksmanship elusive in targeted drug delivery
Edwin P. Rock
Pages: 134-135
Published online: 16 Nov 2004
AbstractforMarksmanship elusive in targeted drug delivery | PDF (603.6 KB)
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