Cancer Biology & Therapy, Volume 4, Issue 11 (2005)

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Cancer Biology & Therapy, Volume 4, Issue 11 (2005)

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Editor's Corner

Editorial
Cover Image
Page: i
Published online: 11 Aug 2005
AbstractforCover Image | PDF (4.1 MB)
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News

News
Extra Centrosomes and Chromosomes Promote Tumors in Mice and May Be a Target for Therapy
Page: 1177
Published online: 11 Aug 2005
AbstractforExtra Centrosomes and Chromosomes Promote Tumors in Mice and May Be a Target for Therapy | PDF (245.6 KB)
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News
Rsf1 Amplification in Poor Prognosis Ovarian Cancer
Page: 1177
Published online: 11 Aug 2005
AbstractforRsf1 Amplification in Poor Prognosis Ovarian Cancer | PDF (245.6 KB)
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News
CD19 mAb Prevents Growth of Malignant B cell Tumors in Mice
Page: 1177
Published online: 11 Aug 2005
AbstractforCD19 mAb Prevents Growth of Malignant B cell Tumors in Mice | PDF (245.6 KB)
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News
Receptor Tyrosine Kinases Including FGFR1 and PDGFRA are Mutated in Glioblastoma
Page: 1177
Published online: 11 Aug 2005
AbstractforReceptor Tyrosine Kinases Including FGFR1 and PDGFRA are Mutated in Glioblastoma | PDF (245.6 KB)
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News
Link Between c-Myc and Metastasis Through Activation of MTA1
Page: 1177
Published online: 11 Aug 2005
AbstractforLink Between c-Myc and Metastasis Through Activation of MTA1 | PDF (245.6 KB)
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News
Blocking TGF-β may Reduce Radiation-Induced Lung Injury
Page: 1177
Published online: 11 Aug 2005
AbstractforBlocking TGF-β may Reduce Radiation-Induced Lung Injury | PDF (245.6 KB)
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News
Antibody-Mediated Targeting of Prostate Stem Cell Antigen in Therapy of Prostate Cancer
Page: 1177
Published online: 11 Aug 2005
AbstractforAntibody-Mediated Targeting of Prostate Stem Cell Antigen in Therapy of Prostate Cancer | PDF (245.6 KB)
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News
Curcumin Blocks IKK to Inhibit Breast Cancer Metastases to the Lungs in Mice
Page: 1177
Published online: 11 Aug 2005
AbstractforCurcumin Blocks IKK to Inhibit Breast Cancer Metastases to the Lungs in Mice | PDF (245.6 KB)
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Review

Review Article
Structural basis for gene activation by p53 family members
Ariane Scoumanne, Kelly Lynn Harms & Xinbin Chen
Pages: 1178-1185
Published online: 11 Aug 2005
AbstractforStructural basis for gene activation by p53 family members | PDF (283.7 KB)
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Clinical Case Report

Case Report
Avoiding glucocorticoid administration in a neurooncological case
Hans Peter Rutz, Silvia Hofer, Pietro E. Peghini, Ursula Gutteck-Amsler, Katharina Rentsch, Peter J. Meier-Abt, Urs R. Meier & René Ludwig Bernays
Pages: 1186-1189
Published online: 11 Aug 2005
AbstractforAvoiding glucocorticoid administration in a neurooncological case | PDF (462.5 KB)
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Commentary

Two targets are better than one, Promising combination therapy to treat breast cancer
Richard A. Franklin, Massimo Libra, Franca Stivala & James A. McCubrey
Pages: 1190-1191
Published online: 11 Aug 2005
AbstractforTwo targets are better than one, Promising combination therapy to treat breast cancer | PDF (161.4 KB)
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Brief Communication

Brief Report
Elevated serum levels of osteopontin in HCV-associated lymphoproliferative disorders
Massimo Libra, Manuela Indelicato, Vallì De Re, Anna Linda Zignego, Annalisa Chiocchetti, Grazia Malaponte, Mario Umberto Dianzani, Ferdinando Nicoletti, Franca Stivala, James A. McCubrey & Maria C. Mazzarino
Pages: 1192-1194
Published online: 11 Aug 2005
AbstractforElevated serum levels of osteopontin in HCV-associated lymphoproliferative disorders | PDF (205.8 KB)
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Research Paper

Article
NF-κB protects rat ARL-6 hepatocellular carcinoma cells against hydrogen peroxide-induced apoptosis
Liang Qiao, Jun Yu, Paul Dent & Geoffrey Farrell
Pages: 1195-1202
Published online: 11 Aug 2005
AbstractforNF-κB protects rat ARL-6 hepatocellular carcinoma cells against hydrogen peroxide-induced apoptosis | PDF (613.4 KB)
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Article
Gene transfer to carcinoma of the breast with fiber-modified adenoviral vectors in a tissue slice model system
Mariam A. Stoff-Khalili, Alexander Stoff, Angel A Rivera, J. Michael Mathis, Maaike Everts, Minghui Wang, Yosuke Kawakami, Reinhard Waehler, Quiana L. Matthews, Masato Yamamoto, Rodney P. Rocconi, Gene P. Siegal, Dirk F. Richter, Peter Dall, Zeng B. Zhu & David T. Curiel
Pages: 1203-1210
Published online: 11 Aug 2005
AbstractforGene transfer to carcinoma of the breast with fiber-modified adenoviral vectors in a tissue slice model system | PDF (525 KB)
  • 322 Views
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Article
Aberrant splicing of cables gene, a CDK regulator, in human cancers
Hui Zhang, Hai Ou Duan, Sandra D. Kirley, Lawrence R. Zukerberg & Chin-Lee Wu
Pages: 1211-1215
Published online: 11 Aug 2005
AbstractforAberrant splicing of cables gene, a CDK regulator, in human cancers | PDF (415.7 KB)
  • 356 Views
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Article
KLF4 and KLF5 regulate proliferation, Apoptosis and invasion in esophageal cancer cells
Yizeng Yang, Bree G. Goldstein, Hann-Hsiang Chao & Jonathan Katz
Pages: 1216-1221
Published online: 11 Aug 2005
AbstractforKLF4 and KLF5 regulate proliferation, Apoptosis and invasion in esophageal cancer cells | PDF (865.7 KB)
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Article
Polymorphism in the hypoxia-inducible factor 1α gene may confer susceptibility to androgen-independent prostate cancer
Cindy H. Chau, Matthew G. Permenter, Seth M. Steinberg, Avi S. Retter, William L. Dahut, Douglas K. Price & William Figg, II
Pages: 1222-1225
Published online: 11 Aug 2005
AbstractforPolymorphism in the hypoxia-inducible factor 1α gene may confer susceptibility to androgen-independent prostate cancer | PDF (490.3 KB)
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Article
Calcitonin induces apoptosis resistance in prostate cancer cell lines against cytotoxic drugs via the Akt/Survivin pathway
Shibu Thomas & Girish M. Shah
Pages: 1226-1233
Published online: 11 Aug 2005
AbstractforCalcitonin induces apoptosis resistance in prostate cancer cell lines against cytotoxic drugs via the Akt/Survivin pathway | PDF (611.7 KB)
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Article
Tumor-targeted therapy with a conditionally replicating mutant of HSV-1 induces regression of xenografted human hepatomas
Feng Xue, Chang-yuan Dong, Yue Su, Hua-bing Zhu, Weifang Ling, Yingle Liu, Hua Xu, Wei Xiao, Shumin Zhou & Yi-peng Qi
Pages: 1234-1239
Published online: 11 Aug 2005
Abstractfor Tumor-targeted therapy with a conditionally replicating mutant of HSV-1 induces regression of xenografted human hepatomas | PDF (645.3 KB)
  • 308 Views
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Article
Cyclic AMP inhibition of proliferation of hepatocellular carcinoma cells Is mediated by Akt
Lunhua Liu, Yili Xie & Liguang Lou
Pages: 1240-1247
Published online: 11 Aug 2005
AbstractforCyclic AMP inhibition of proliferation of hepatocellular carcinoma cells Is mediated by Akt | PDF (747.3 KB)
  • 609 Views
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Article
Effects of polyphyllin D, a steroidal saponin in Paris Polyphylla, in growth inhibition of human breast cancer cells and in xenograft
Mei-Sze Lee, Judy Yuet-Wa Chan, Siu-Kai Kong, Biao Yu, Vincent Ooi Eng-Choon, Henry Wong Nai-Ching, Thomas Mak Chung-Wai & Kwok-Pui Fung
Pages: 1248-1254
Published online: 11 Aug 2005
AbstractforEffects of polyphyllin D, a steroidal saponin in Paris Polyphylla, in growth inhibition of human breast cancer cells and in xenograft | PDF (623.2 KB)
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Article
Adenoviral E1a expression levels affect virus-selective replication in human cancer cells
Xinyu Zheng, Xiao-Mei Rao, Christina Snodgrass, Min Wang, Yanbin Dong, Kelly M. McMasters & H. Sam Zhou
Pages: 1255-1262
Published online: 11 Aug 2005
AbstractforAdenoviral E1a expression levels affect virus-selective replication in human cancer cells | PDF (805.7 KB)
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Article
Prostaglandin E2 drives cyclooxygenase 2 expression via cyclic AMP response element activation in human pancreatic cancer cells
Maria S. Pino, Steffan T. Nawrocki, Francesco Cognetti, James L. Abruzzese, Henry Xiong & David J. McConkey
Pages: 1263-1269
Published online: 11 Aug 2005
AbstractforProstaglandin E2 drives cyclooxygenase 2 expression via cyclic AMP response element activation in human pancreatic cancer cells | PDF (545.5 KB)
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Article
Activating mutations in c-KIT and PDGFRα are exclusively found in gastrointestinal stromal tumors and not in other tumors overexpressing these imatinib mesylate target genes
Kk Burger, Michael A. den Bakker, Johan M. Kros, Alex M. de Bruin, Walter Oosterhuis, Henry F.G.M. van den Ingh, Erwin van der Harst, Hans P. de Schipper, Erik A.C. Wiemer & Kees Nooter
Pages: 1270-1274
Published online: 11 Aug 2005
AbstractforActivating mutations in c-KIT and PDGFRα are exclusively found in gastrointestinal stromal tumors and not in other tumors overexpressing these imatinib mesylate target genes | PDF (286.5 KB)
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Article
Transient exposure of mammary tumors to PD184352 and UCN-01 causes tumor cell death in vivo and prolonged suppression of tumor re-growth
William Hawkins, Clint Mitchell, Robert McKinstry, Donna Gilfor, James Starkey, Yun Dai, Kathy Dawson, Viswanathan Ramakrishnan, John D. Roberts, Adly Yacoub, Steven Grant & Paul Dent
Pages: 1275-1284
Published online: 11 Aug 2005
AbstractforTransient exposure of mammary tumors to PD184352 and UCN-01 causes tumor cell death in vivo and prolonged suppression of tumor re-growth | PDF (832.2 KB)
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Article
Mxi1 is induced by hypoxia in a HIF-1–dependent manner and protects cells from c-Myc-induced apoptosis
Paul G. Corn, M. Stacey Ricci, Kimberly A. Scata, Andrew M. Arsham, M. Celeste Simon, David T. Dicker & Wafik S. El-Deiry
Pages: 1285-1294
Published online: 11 Aug 2005
AbstractforMxi1 is induced by hypoxia in a HIF-1–dependent manner and protects cells from c-Myc-induced apoptosis | PDF (575 KB)
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Profiles and Legacies

Editorial
John H. Glick, M.D.
John H. Glick
Page: 1295
Published online: 11 Aug 2005
AbstractforJohn H. Glick, M.D. | PDF (425.4 KB)
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