Cancer Biology & Therapy, Volume 4, Issue 8 (2005)

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Cancer Biology & Therapy, Volume 4, Issue 8 (2005)

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Editor's Corner

Editorial
Cover Image
Page: i
Published online: 12 Jul 2005
AbstractforCover Image | PDF (2.5 MB)
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News

News
Human Mesenchymal Precursors Derived from Embryonic Stem Cells have Specialized Differentiation Potential and are not Tumorigenic
Page: 804
Published online: 12 Jul 2005
AbstractforHuman Mesenchymal Precursors Derived from Embryonic Stem Cells have Specialized Differentiation Potential and are not Tumorigenic | PDF (746.7 KB)
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News
High Resolution SNP Arrays Identify Amplified Regions in Lung Cancer
Page: 804
Published online: 12 Jul 2005
AbstractforHigh Resolution SNP Arrays Identify Amplified Regions in Lung Cancer | PDF (746.7 KB)
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News
Cutting Edge Matrix Assembly (CEMA): A New High Density Tissue Microarray Technology
Page: 804
Published online: 12 Jul 2005
AbstractforCutting Edge Matrix Assembly (CEMA): A New High Density Tissue Microarray Technology | PDF (746.7 KB)
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News
Regulating ETS Transcription Factor Function by Altering a Flexible Domain
Page: 804
Published online: 12 Jul 2005
AbstractforRegulating ETS Transcription Factor Function by Altering a Flexible Domain | PDF (746.7 KB)
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News
Are p53 Post-Translational Modifications Required for its Function In Vivo?
Page: 804
Published online: 12 Jul 2005
AbstractforAre p53 Post-Translational Modifications Required for its Function In Vivo? | PDF (746.7 KB)
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News
Identification of an Amplified Transcription Factor (MITF) in Melanoma
Page: 804
Published online: 12 Jul 2005
AbstractforIdentification of an Amplified Transcription Factor (MITF) in Melanoma | PDF (746.7 KB)
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News
A Genome-Wide Map of Active Gene Promoters
Page: 804
Published online: 13 Jul 2005
AbstractforA Genome-Wide Map of Active Gene Promoters | PDF (746.7 KB)
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News
PGE2 Produced by Lung Cancer Suppresses Immune Function Through T-regulatory Cells and can be Blocked by the COX2 Inhibitor Celebrex
Page: 804
Published online: 15 Jul 2005
AbstractforPGE2 Produced by Lung Cancer Suppresses Immune Function Through T-regulatory Cells and can be Blocked by the COX2 Inhibitor Celebrex | PDF (746.7 KB)
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Review

Review Article
Metastasis suppressor genes: From gene identification to protein function and regulation
Jonathan C. Berger, Donald J. Vander Griend, Victoria L. Robinson, Jonathan A. Hickson & Carrie W. Rinker-Schaeffer
Pages: 805-812
Published online: 23 Sep 2005
AbstractforMetastasis suppressor genes: From gene identification to protein function and regulation | PDF (452.7 KB)
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Journal Club

Cyclooxygenase-2 and angiogenesis in prostate cancer
Victoria L. Tkacz, Tanyifor M. Tohnya & William Figg, II
Pages: 813-814
Published online: 23 Sep 2005
AbstractforCyclooxygenase-2 and angiogenesis in prostate cancer | PDF (149.5 KB)
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Brief Communication

Brief Report
Identification of OATP1B3 as a high-affinity hepatocellular transporter of paclitaxel
Nicola F. Smith, Milin R. Acharya, Neil Desai, William Figg, II & Alex Sparreboom
Pages: 815-818
Published online: 23 Sep 2005
AbstractforIdentification of OATP1B3 as a high-affinity hepatocellular transporter of paclitaxel | PDF (465.4 KB)
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Research Paper

Article
Analysis of the mononuclear inflammatory cell infiltrate in the nontumorigenic, Pretumorigenic and tumorigenic keratinocytic hyperproliferative lesions of the skin
Mahmoud R. Hussein & Rabab A. Ahmed
Pages: 819-821
Published online: 23 Sep 2005
AbstractforAnalysis of the mononuclear inflammatory cell infiltrate in the nontumorigenic, Pretumorigenic and tumorigenic keratinocytic hyperproliferative lesions of the skin | PDF (449.6 KB)
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Article
RNA interference remarkably suppresses bcl-2 gene expression in cancer cells in vitro and in vivo
Geng-Feng Fu, Xue-Hong Lin, Qing-Wang Han, Ye-Fen Xu, Dan Guo, Gen-Xing Xu & Ya-Yi Hou
Pages: 822-829
Published online: 23 Sep 2005
AbstractforRNA interference remarkably suppresses bcl-2 gene expression in cancer cells in vitro and in vivo | PDF (559.1 KB)
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Commentary

RNA interference: A new therapeutic strategy of cancer
Yongquan Shi, Zhiguo Liu, Dexin Zhang & Daiming Fan
Pages: 830-831
Published online: 23 Sep 2005
AbstractforRNA interference: A new therapeutic strategy of cancer | PDF (165.1 KB)
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Research Paper

Article
Nuclear chromatin patterns in 3 glucocorticoid-resistant RPMI 8226 human myeloma cell sub-lines: Correlations with cell growth and immunological phenotype
Vincent Genty, Victoria El-Khoury, Françoise Liautaud-Roger, Gérard Dine & Jean Dufer
Pages: 832-839
Published online: 23 Sep 2005
AbstractforNuclear chromatin patterns in 3 glucocorticoid-resistant RPMI 8226 human myeloma cell sub-lines: Correlations with cell growth and immunological phenotype | PDF (441.6 KB)
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Article
Enhanced therapeutic effect by combination of tumor-targeting salmonella and endostatin in murine melanoma model
Li-Jun Jia, Han-Mei Xu, Ding-Yuan Ma, Qin-Gang Hu, Xiao-Feng Huang, Wen-Hui Jiang, Shu-Feng Li, Kun-Zhi Jia, Qi-Lai Huang & Zi-Chun Hua
Pages: 840-845
Published online: 23 Sep 2005
AbstractforEnhanced therapeutic effect by combination of tumor-targeting salmonella and endostatin in murine melanoma model | PDF (699.6 KB)
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Commentary

Combination therapy with bacteria and angiogenesis inhibitors: Strangling cancer without mercy
Shibin Zhou
Pages: 846-847
Published online: 23 Sep 2005
AbstractforCombination therapy with bacteria and angiogenesis inhibitors: Strangling cancer without mercy | PDF (160.9 KB)
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Research Paper

Article
In vivo and in vitro inhibition of pancreatic cancer growth by targeted alpha therapy using 213Bi-CHX.A”-C595
Chang F. Qu, Yan J. Song, Syed M.A. Rizvi, Yong Li, Ross Smith, Alan Perkins, Alfred Morgenstern, Martin W Brechbiel & Barry J Allen
Pages: 848-853
Published online: 23 Sep 2005
AbstractforIn vivo and in vitro inhibition of pancreatic cancer growth by targeted alpha therapy using 213Bi-CHX.A”-C595 | PDF (701.6 KB)
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Article
Radiolabeling and biological evaluation of DOTA-Ph-Al derivative conjugated to anti-EGFR antibody ior egf/r3 for targeted tumor imaging and therapy
Puja Panwar, Normando Iznaga-Escobar, Pushpa Mishra, Vibha Shrivastava, Rakesh Kumar Sharma, Ramesh Chandra & Anil Kumar Mishra
Pages: 854-860
Published online: 23 Sep 2005
AbstractforRadiolabeling and biological evaluation of DOTA-Ph-Al derivative conjugated to anti-EGFR antibody ior egf/r3 for targeted tumor imaging and therapy | PDF (747.2 KB)
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Article
The cables gene on chromosome 18Q regulates colon cancer progression in vivo
Sandra D. Kirley, Massimo D'Apuzzo, Gregory Y. Lauwers, Fiona Graeme-Cook, Daniel C. Chung & Lawrence R. Zukerberg
Pages: 861-863
Published online: 23 Sep 2005
AbstractforThe cables gene on chromosome 18Q regulates colon cancer progression in vivo | PDF (767.2 KB)
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Commentary

‘Cables’ suspends cancer in mice
Challice L. Bonifant & Todd Waldman
Pages: 864-865
Published online: 23 Sep 2005
Abstractfor‘Cables’ suspends cancer in mice | PDF (153 KB)
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Research Paper

Article
Potentiation of the antitumoral activity of gemcitabine and paclitaxel in combination on human breast cancer cells
Gabriella Zupi, Marco Scarsella, Carmen D'Angelo, Annamaria Biroccio, Giancarlo Paoletti, Massimo Lopez & Carlo Leonetti
Pages: 866-871
Published online: 23 Sep 2005
AbstractforPotentiation of the antitumoral activity of gemcitabine and paclitaxel in combination on human breast cancer cells | PDF (618.1 KB)
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Commentary

Importance of rational pre-clinical development: Gemcitabine comes of age
Ramona F. Swaby & Kapil N. Bhalla
Pages: 872-873
Published online: 23 Sep 2005
AbstractforImportance of rational pre-clinical development: Gemcitabine comes of age | PDF (138.5 KB)
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Research Paper

Article
PE, a new sulfated saponin from sea cucumber, Exhibits anti-angiogenic and anti-tumor activities in vitro and in vivo
Fang Tian, Xiongwen Zhang, Yungyuang Tong, Yanghua Yi, Shilong Zhang, Ling Li, Peng Sun, Liping Lin & Jian Ding
Pages: 874-882
Published online: 23 Sep 2005
AbstractforPE, a new sulfated saponin from sea cucumber, Exhibits anti-angiogenic and anti-tumor activities in vitro and in vivo | PDF (960.3 KB)
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Commentary

Marine-derived cancer therapeutics making a splash
Timothy K. MacLachlan & Jan Pinkas
Pages: 883-884
Published online: 23 Sep 2005
AbstractforMarine-derived cancer therapeutics making a splash | PDF (197.2 KB)
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Research Paper

Article
Bioluminescent imaging of TRAIL-induced apoptosis through detection of caspase activation following cleavage of DEVD-aminoluciferin
Jue Judy Liu, Wenge Wang, David T. Dicker & Wafik S. El-Deiry
Pages: 885-892
Published online: 23 Sep 2005
AbstractforBioluminescent imaging of TRAIL-induced apoptosis through detection of caspase activation following cleavage of DEVD-aminoluciferin | PDF (1.5 MB)
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Article
Acridine derivatives activate p53 and induce tumor cell death through bax
Wenge Wang, William C. Ho, David T. Dicker, Colin MacKinnon, Jeffrey D. Winkler, Ronen Marmorstein & Wafik S. El-Deiry
Pages: 893-898
Published online: 23 Sep 2005
AbstractforAcridine derivatives activate p53 and induce tumor cell death through bax | PDF (691.1 KB)
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Commentary

Could the combination of celecoxib and 4HPR be an effective lung cancer treatment?
Durga P. Cherukuri & Mark A. Nelson
Pages: 899-900
Published online: 23 Sep 2005
AbstractforCould the combination of celecoxib and 4HPR be an effective lung cancer treatment? | PDF (156.8 KB)
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Profiles and Legacies

Editorial
Chasing cancer: From genes to drugs
George C. Prendergast
Pages: 901-905
Published online: 23 Sep 2005
AbstractforChasing cancer: From genes to drugs | PDF (772.5 KB)
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