Cancer Biology & Therapy, Volume 4, Issue 9 (2005)

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Cancer Biology & Therapy, Volume 4, Issue 9 (2005)

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Editor's Corner

Editorial
Cover Image
Page: i
Published online: 22 Aug 2005
AbstractforCover Image | PDF (1.3 MB)
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News

News
DOCK180 and PIP3 Gradient Orchestrate Cell Movement That May Offer Clues to Blocking Metastasis
Page: 917
Published online: 21 Oct 2005
AbstractforDOCK180 and PIP3 Gradient Orchestrate Cell Movement That May Offer Clues to Blocking Metastasis | PDF (658.5 KB)
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News
Genes Predict Metastatic Spread to the Lungs in Breast Cancer
Page: 917
Published online: 01 Sep 2005
AbstractforGenes Predict Metastatic Spread to the Lungs in Breast Cancer | PDF (658.5 KB)
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News
TRPS-1, a DNA-Binding Protein and Potential Tumor Antigen, is Overexpressed in Breast Cancer
Page: 917
Published online: 02 Aug 2005
AbstractforTRPS-1, a DNA-Binding Protein and Potential Tumor Antigen, is Overexpressed in Breast Cancer | PDF (658.5 KB)
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News
Cyclin D1 Inhibits BRCA1 Binding to the Estrogen Receptor
Page: 917
Published online: 15 Aug 2005
AbstractforCyclin D1 Inhibits BRCA1 Binding to the Estrogen Receptor | PDF (658.5 KB)
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News
Targeting HIF at the Right Time to Enhance Effect of Radiation
Page: 917
Published online: 15 Aug 2005
AbstractforTargeting HIF at the Right Time to Enhance Effect of Radiation | PDF (658.5 KB)
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News
Monitoring IKK Targeting in Real-Time In Vivo with Bioluminescence
Page: 917
Published online: 15 Aug 2005
AbstractforMonitoring IKK Targeting in Real-Time In Vivo with Bioluminescence | PDF (658.5 KB)
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News
Hyaluronidase as a Therapeutic Target in Cancer: A Matter of Too Little or Too Much
Page: 917
Published online: 15 Aug 2005
AbstractforHyaluronidase as a Therapeutic Target in Cancer: A Matter of Too Little or Too Much | PDF (658.5 KB)
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News
Gefitinib but not Cetuximab Shuts Down Mutant EGFR Signaling
Page: 917
Published online: 29 Aug 2005
AbstractforGefitinib but not Cetuximab Shuts Down Mutant EGFR Signaling | PDF (658.5 KB)
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News
Non-Invasive Fluorescence Detection of Cancer-Associated Protease Activity
Page: 917
Published online: 31 Aug 2005
AbstractforNon-Invasive Fluorescence Detection of Cancer-Associated Protease Activity | PDF (658.5 KB)
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Review

Review Article
Nucleophosmin/B23, a multifunctional protein that can regulate apoptosis
Keqiang Ye
Pages: 918-923
Published online: 23 Jun 2005
AbstractforNucleophosmin/B23, a multifunctional protein that can regulate apoptosis | PDF (229.9 KB)
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Review Article
Cancer cell immune escape and tumor progression by exploitation of anti-inflammatory and pro-inflammatory responses
Ryungsa Kim, Manabu Emi & Kazuaki Tanabe
Pages: 924-933
Published online: 23 Jun 2005
AbstractforCancer cell immune escape and tumor progression by exploitation of anti-inflammatory and pro-inflammatory responses | PDF (805.4 KB)
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Brief Communication

Brief Report
BRCA2-deficient CAPAN-1 cells are extremely sensitive to the inhibition of poly (ADP-ribose) polymerase: An issue of potency
Nuala McCabe, Christopher J. Lord, Andrew NJ Tutt, Niall Martin, Graeme C.M. Smith & Alan Ashworth
Pages: 934-936
Published online: 23 Jun 2005
AbstractforBRCA2-deficient CAPAN-1 cells are extremely sensitive to the inhibition of poly (ADP-ribose) polymerase: An issue of potency | PDF (236.5 KB)
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Brief Report
Noninvasive fluorescence imaging of cell death in fresh human colon epithelia treated with 5-fluorouracil, CPT-11 and/or TRAIL
Niklas Finnberg, Seok-Hyun Kim, Emma E. Furth, Jue Judy Liu, Pierre Russo, David A. Piccoli, Adda Grimberg & Wafik S. El-Deiry
Pages: 937-942
Published online: 23 Jun 2005
AbstractforNoninvasive fluorescence imaging of cell death in fresh human colon epithelia treated with 5-fluorouracil, CPT-11 and/or TRAIL | PDF (763.3 KB)
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Research Paper

Article
MAGED4 – expression in renal cell carcinoma and identification of an HLA-A*25-restricted MHC class I ligand from solid tumor tissue
Björn F. Krämer, Oliver Schoor, Tobias Krüger, Christian Reichle, Margaret Müller, Toni Weinschenk, Jörg Hennenlotter, Arnulf Stenzl, Hans-Georg Rammensee & Stefan Stevanovic
Pages: 943-948
Published online: 23 Jun 2005
AbstractforMAGED4 – expression in renal cell carcinoma and identification of an HLA-A*25-restricted MHC class I ligand from solid tumor tissue | PDF (354.6 KB)
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Article
Molecular pathways in the chemosensitization of cisplatin by quercetin in human head and neck cancer
Himani Sharma, Sudip Sen & Neeta Singh
Pages: 949-955
Published online: 23 Jun 2005
AbstractforMolecular pathways in the chemosensitization of cisplatin by quercetin in human head and neck cancer | PDF (630.4 KB)
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Article
Signal therapy of breast cancers by the HDAC inhibitor FK228 that blocks the activation of PAK1 and abrogates the tamoxifen-resistance
Yumiko Hirokawa, Melissa Arnold, Hidenori Nakajima, John Zalcberg & Hiroshi Maruta
Pages: 956-960
Published online: 23 Jun 2005
AbstractforSignal therapy of breast cancers by the HDAC inhibitor FK228 that blocks the activation of PAK1 and abrogates the tamoxifen-resistance | PDF (541.9 KB)
  • 530 Views
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Article
RNA interference (RNAi) for extracellular signal-regulated kinase 1 (ERK1) alone is sufficient to suppress cell viability in ovarian cancer cells
Pingyu Zeng, Heather A. Wagoner, Ora Hirsch Pescovitz & Rosemary Steinmetz
Pages: 961-967
Published online: 23 Jun 2005
AbstractforRNA interference (RNAi) for extracellular signal-regulated kinase 1 (ERK1) alone is sufficient to suppress cell viability in ovarian cancer cells | PDF (741.5 KB)
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Article
Suppression of MUC1 synthesis downregulates expression of the epidermal growth factor receptor
Xiaojing Li, Li Wang, David P. Nunes, Robert F. Troxler & Gwynneth D. Offner
Pages: 968-973
Published online: 23 Jun 2005
AbstractforSuppression of MUC1 synthesis downregulates expression of the epidermal growth factor receptor | PDF (796.6 KB)
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Article
Downregulation of survivin by RNAi inhibits the growth of esophageal carcinoma cells
Yihua Wang, Hongxia Zhu, Lanping Quan, Jinfeng Bai, Guo Zhang, Qimin Zhan & Ningzhi Xu
Pages: 974-978
Published online: 23 Jun 2005
AbstractforDownregulation of survivin by RNAi inhibits the growth of esophageal carcinoma cells | PDF (385 KB)
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Article
Elevated sphingomyelinase activity and ceramide concentration in serum of patients undergoing high dose spatially fractionated radiation treatment: Implications for endothelial apoptosis
Sabapathi Sathishkumar, Boris Boyanovski, Alexander Karakashian, Krassimira A. Rozenova, Natalia V. Giltiay, Mahesh Kudrimoti, Mohammed Mohiuddin, Mansoor M. Ahmed & Mariana Nikolova-Karakashian
Pages: 979-986
Published online: 23 Jun 2005
AbstractforElevated sphingomyelinase activity and ceramide concentration in serum of patients undergoing high dose spatially fractionated radiation treatment: Implications for endothelial apoptosis | PDF (595.8 KB)
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Article
Targeting of c-Met and urokinase expressing human glioma cell lines by retrovirus vector displaying single-chain variable fragment antibody
Sounkary K. Solly, Tuan Huy Nguyen, Anne Weber & Philippe Horellou
Pages: 987-992
Published online: 23 Jun 2005
AbstractforTargeting of c-Met and urokinase expressing human glioma cell lines by retrovirus vector displaying single-chain variable fragment antibody | PDF (258.9 KB)
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Article
Preliminary investigation of the inhibitory effects of the tyroservaltide (YSV) tripeptide on human hepatocarcinoma BEL-7402
Jing Jia, Rong Lu, Shuang Qiu, Huiqiang Li, Xuchun Che, Pengpeng Zhao, Mengjue Jin, Haixian Yang, Gang Lin & Zhi Yao
Pages: 993-997
Published online: 23 Jun 2005
AbstractforPreliminary investigation of the inhibitory effects of the tyroservaltide (YSV) tripeptide on human hepatocarcinoma BEL-7402 | PDF (492.1 KB)
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Article
Psoriasin (S100A7) and calgranulin-B (S100A9) induction is dependent on reactive oxygen species and is downregulated by Bcl-2 and antioxidants
Hanna Carlsson, Maria Yhr, Stina Petersson, Nicole Collins, Komelia Polyak & Charlotte Enerbäck
Pages: 998-1005
Published online: 23 Jun 2005
AbstractforPsoriasin (S100A7) and calgranulin-B (S100A9) induction is dependent on reactive oxygen species and is downregulated by Bcl-2 and antioxidants | PDF (541.7 KB)
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Article
Role of p53/p21Waf1/Cip1 in the regulation of polyamine analogue-induced growth inhibition and cell death in human breast cancer cells
Yi Huang, Allison Pledgie, Ethel Rubin, Laurence J. Marton, Patrick M. Woster, Saraswati Sukumar, Robert A. Casero Jr.Nancy E. Davidson
Pages: 1006-1013
Published online: 23 Jun 2005
AbstractforRole of p53/p21Waf1/Cip1 in the regulation of polyamine analogue-induced growth inhibition and cell death in human breast cancer cells | PDF (839 KB)
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Article
Heterogeneity in non-invasive detection of apoptosis among human tumor cell lines using annexin-V tagged with EGFP or Qdot-705
David T. Dicker, Seok-Hyun Kim, Zhaoyu Jin & Wafik S. El-Deiry
Pages: 1014-1017
Published online: 23 Jun 2005
AbstractforHeterogeneity in non-invasive detection of apoptosis among human tumor cell lines using annexin-V tagged with EGFP or Qdot-705 | PDF (690.4 KB)
  • 616 Views
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Article
Whole-genome expression profiling of the melanoma progression pathway reveals marked molecular differences between nevi/melanoma in situ and advanced-stage melanomas
Amanda Pfaff Smith, Keith Hoek & Dorothea Becker
Pages: 1018-1029
Published online: 23 Jun 2005
AbstractforWhole-genome expression profiling of the melanoma progression pathway reveals marked molecular differences between nevi/melanoma in situ and advanced-stage melanomas | PDF (906.4 KB)
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Commentary

Ins and outs of taxanes
Gary D. Kruh
Pages: 1030-1032
Published online: 23 Jun 2005
AbstractforIns and outs of taxanes | PDF (205 KB)
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Hypoxia effects: Implications for maspin regulation of the uPA/uPAR complex
Jeremy S. Schaefer & Ming Zhang
Pages: 1033-1035
Published online: 23 Jun 2005
AbstractforHypoxia effects: Implications for maspin regulation of the uPA/uPAR complex | PDF (171.3 KB)
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Profiles in Science

Editorial
Cancer biology is the foundation for therapy
Isaiah J. Fidler
Pages: 1036-1039
Published online: 23 Jun 2005
AbstractforCancer biology is the foundation for therapy | PDF (823.2 KB)
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