Cancer Biology & Therapy, Volume 5, Issue 8 (2006)

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Cancer Biology & Therapy, Volume 5, Issue 8 (2006)

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Editor's Corner

Editorial
Cover Image
Page: i
Published online: 10 Aug 2006
AbstractforCover Image | PDF (1.7 MB)
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Editorial
Robert B. Dickson
na
Pages: 895-896
Published online: 21 Sep 2006
AbstractforRobert B. Dickson | PDF (127.8 KB)
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News

News
Differences Between Normal and Leukemia Stem Cells
Pages: 897-900
Published online: 21 Sep 2006
AbstractforDifferences Between Normal and Leukemia Stem Cells | PDF (442.1 KB)
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News
Stress and the Spread of Ovarian Cancer in Mice
Pages: 897-900
Published online: 21 Sep 2006
AbstractforStress and the Spread of Ovarian Cancer in Mice | PDF (442.1 KB)
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News
Acetyl CoA Production Provides Link between Sugar Metabolism and Gene Expression
Pages: 897-900
Published online: 21 Sep 2006
AbstractforAcetyl CoA Production Provides Link between Sugar Metabolism and Gene Expression | PDF (442.1 KB)
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News
Targeting ALDH to Block Hematopoietic Stem Cell Differentiation
Pages: 897-900
Published online: 21 Sep 2006
AbstractforTargeting ALDH to Block Hematopoietic Stem Cell Differentiation | PDF (442.1 KB)
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Review

Review Article
Stem cells in prostate cancer: Resolving the castrate-resistant conundrum and implications for hormonal therapy
Nima Sharifi, Brian T. Kawasaki, Elaine M. Hurt & William L. Farrar
Pages: 901-906
Published online: 26 May 2006
AbstractforStem cells in prostate cancer: Resolving the castrate-resistant conundrum and implications for hormonal therapy | PDF (597.8 KB)
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Journal Club

Ubiquitination of Myc: Flipping the switch
Amelie Boquoi & Gregory H. Enders
Pages: 907-908
Published online: 26 May 2006
AbstractforUbiquitination of Myc: Flipping the switch | PDF (175.3 KB)
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Lysyl oxidase (LOX) and hypoxia-induced metastases
Amy M. Sion & William Figg, II
Pages: 909-911
Published online: 26 May 2006
AbstractforLysyl oxidase (LOX) and hypoxia-induced metastases | PDF (192.1 KB)
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Clinical Case Report

Case Report
Long term responses with cetuximab therapy in glioblastoma multiforme
Cristóbal Belda-Iniesta, Javier de Castro Carpeño, Enrique Casado Saenz, Manuel Gutiérrez, Rosario Perona & Manuel González-Barón
Pages: 912-914
Published online: 26 May 2006
AbstractforLong term responses with cetuximab therapy in glioblastoma multiforme | PDF (771.5 KB)
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Brief Communication

Brief Report
Dexamethasone protects against cisplatin-induced activation of the mitochondrial apoptotic pathway in human osteosarcoma cells
Stefan Meyer, Helen Kalirai & Tim Eden
Pages: 915-920
Published online: 26 May 2006
AbstractforDexamethasone protects against cisplatin-induced activation of the mitochondrial apoptotic pathway in human osteosarcoma cells | PDF (679.5 KB)
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Commentary

Benefits and adverse effects of anti-emetic glucocorticoids in cancer
Ansgar Brüning, Klaus Friese & Ingo B. Runnebaum
Pages: 921-922
Published online: 26 May 2006
AbstractforBenefits and adverse effects of anti-emetic glucocorticoids in cancer | PDF (172.8 KB)
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Brief Communication

Brief Report
A proposed clinical test for monitoring fluoropyrimidine therapy: Detection and stability of thymidylate synthase ternary complexes
Jonathan R. Brody, Eike Gallmeier, Kiyoshi Yoshimura, Tomas Hucl, Peter Kulesza, Marcia I. Canto, Ralph H. Hruban, Richard D. Schulick & Scott E. Kern
Pages: 923-927
Published online: 26 May 2006
AbstractforA proposed clinical test for monitoring fluoropyrimidine therapy: Detection and stability of thymidylate synthase ternary complexes | PDF (471.5 KB)
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Brief Report
Recurrent KRAS codon 146 mutations in human colorectal cancer
Sarah Edkins, Sarah O'Meara, Adrian Parker, Claire Stevens, Marcelo Reis, Siân Jones, Chris Greenman, Helen Davies, Gillian Dalgliesh, Simon Forbes, Chris Hunter, Raffaella Smith, Philip Stephens, Peter Goldstraw, Andrew Nicholson, Tsun Leung Chan, Victor E. Velculescu, Siu Tsan Yuen, Suet Yi Leung, Michael R. Stratton & P. Andrew Futreal
Pages: 928-932
Published online: 26 May 2006
AbstractforRecurrent KRAS codon 146 mutations in human colorectal cancer | PDF (353.4 KB)
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Research Paper

Article
Dexamethasone decreases xenograft response to paclitaxel through inhibition of tumor cell apoptosis
Diana Pang, Marsha Kocherginsky, Thomas Krausz, So-Young Kim & Suzanne Conzen
Pages: 933-940
Published online: 26 May 2006
AbstractforDexamethasone decreases xenograft response to paclitaxel through inhibition of tumor cell apoptosis | PDF (499 KB)
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Commentary

New in vivo results support concerns about harmful effects of cortisone drugs in the treatment of breast cancer
Ingrid Herr & Markus W. Büchler
Pages: 941-942
Published online: 26 May 2006
AbstractforNew in vivo results support concerns about harmful effects of cortisone drugs in the treatment of breast cancer | PDF (172 KB)
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Research Paper

Article
Impaired cisplatin influx in an A2780 mutant cell line: Evidence for a putative, cis-configuration-specific, platinum influx transporter
Jozien Helleman, Kk Burger, Irene H.L. Hamelers, Antonius W. M. Boersma, Anton I.P.M. de Kroon, Gerrit Stoter & Kees Nooter
Pages: 943-949
Published online: 26 May 2006
AbstractforImpaired cisplatin influx in an A2780 mutant cell line: Evidence for a putative, cis-configuration-specific, platinum influx transporter | PDF (266.3 KB)
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Article
TRF2 promotes multidrug resistance in gastric cancer cells
Hanbing Ning, Tingting Li, Lina Zhao, Ting Li, Jichang Li, Jie Liu, Zhiguo Liu & Daiming Fan
Pages: 950-956
Published online: 26 May 2006
AbstractforTRF2 promotes multidrug resistance in gastric cancer cells | PDF (622 KB)
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Commentary

Resistance from the flanks: A role for telomere repeat factor 2 in chemotherapeutic drug resistance
Paul M. Lieberman
Pages: 957-958
Published online: 26 May 2006
AbstractforResistance from the flanks: A role for telomere repeat factor 2 in chemotherapeutic drug resistance | PDF (165.6 KB)
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Research Paper

Article
Activation of ATM and histone H2AX phosphorylation induced by mitoxantrone but not by topotecan is prevented by the antioxidant N-acetyl-L-Cysteine
Xuan Huang, Akira Kurose, Toshiki Tanaka, Frank Traganos, Wei Dai & Zbigniew Darzynkiewicz
Pages: 959-964
Published online: 26 May 2006
AbstractforActivation of ATM and histone H2AX phosphorylation induced by mitoxantrone but not by topotecan is prevented by the antioxidant N-acetyl-L-Cysteine | PDF (522.5 KB)
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Commentary

Important differences between topoisomerase-I and -II targeting agents
Shantanu Banerji & Marek Los
Pages: 965-966
Published online: 26 May 2006
AbstractforImportant differences between topoisomerase-I and -II targeting agents | PDF (167.2 KB)
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Research Paper

Article
Proteomic analysis of proteins involved in mitochondria-to-nucleus retrograde response in human cancer cells
Mariola Kulawiec, Hilal Arnouk, Mohamed Mokhtar Desouki, Latif Kazim, Ivan Still & Keshav K. Singh
Pages: 967-975
Published online: 26 May 2006
AbstractforProteomic analysis of proteins involved in mitochondria-to-nucleus retrograde response in human cancer cells | PDF (589.2 KB)
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Commentary

Understanding mitochondrial genetic abnormalities in cancer etiology: A proteomics approach
Paul R. Graves
Pages: 976-977
Published online: 26 May 2006
AbstractforUnderstanding mitochondrial genetic abnormalities in cancer etiology: A proteomics approach | PDF (169.8 KB)
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Research Paper

Article
Growth arrest induced by C75, A fatty acid synthase inhibitor, Was partially modulated by p38 MAPK but not by p53 in human hepatocellular carcinoma
Yan Gao, Li-Ping Lin, Cai-Hua Zhu, Yi Chen, Yong-Tai Hou & Jian Ding
Pages: 978-985
Published online: 26 May 2006
AbstractforGrowth arrest induced by C75, A fatty acid synthase inhibitor, Was partially modulated by p38 MAPK but not by p53 in human hepatocellular carcinoma | PDF (796 KB)
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Commentary

Cancer therapy: Back to metabolism
Harmeet Malhi & Gregory J. Gores
Pages: 986-987
Published online: 26 May 2006
AbstractforCancer therapy: Back to metabolism | PDF (171.5 KB)
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Research Paper

Article
Biphasic regulation of extracellular signal-regulated kinases by scalaradial, A secretory phospholipase A2 inhibitor
Yili Xie, Zhiguo Yu, Lunhua Liu, Yuewei Guo & Liguang Lou
Pages: 988-992
Published online: 26 May 2006
AbstractforBiphasic regulation of extracellular signal-regulated kinases by scalaradial, A secretory phospholipase A2 inhibitor | PDF (394.8 KB)
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Article
DNA methylation alterations in urothelial carcinoma
Anne Neuhausen, Andrea R. Florl, Marc-Oliver Grimm & Wolfgang A. Schulz
Pages: 993-1001
Published online: 26 May 2006
AbstractforDNA methylation alterations in urothelial carcinoma | PDF (1,012.4 KB)
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Article
Suppression of human brain tumor with interference RNA specific for tenascin-C
Ryszard Zukiel, Stanislaw Nowak, Eliza Wyszko, Katarzyna Rolle, Iwona Gawronska, Miroslawa Z. Barciszewska & Jan Barciszewski
Pages: 1002-1007
Published online: 26 May 2006
AbstractforSuppression of human brain tumor with interference RNA specific for tenascin-C | PDF (571.6 KB)
  • 684 Views
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Article
PPARγ activator rosiglitazone inhibits cell migration via upregulation of PTEN in human hepatocarcinoma cell line BEL-7404
Wen Zhang, Nan Wu, Zengxia Li, Liying Wang, Jiawei Jin & Xi-Liang Zha
Pages: 1008-1014
Published online: 26 May 2006
AbstractforPPARγ activator rosiglitazone inhibits cell migration via upregulation of PTEN in human hepatocarcinoma cell line BEL-7404 | PDF (596 KB)
  • 321 Views
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Article
Combination of gemcitabine antagonizes antitumor activity of paclitaxel through prevention of mitotic arrest and apoptosis
Meihua Sui, Xiaoxiong Xiong, Andrew S. Kraft & Weimin Fan
Pages: 1015-1021
Published online: 26 May 2006
AbstractforCombination of gemcitabine antagonizes antitumor activity of paclitaxel through prevention of mitotic arrest and apoptosis | PDF (844.1 KB)
  • 234 Views
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Article
Inhibition of the CaM-Kinases augments cell death in response to oxygen radicals and oxygen radical inducing cancer therapies in MCF-7 human breast cancer cells
Oswaldo Rodriguez-Mora, Michelle M. LaHair, Mark J. Evans, Charles J. Kovacs, Ron R. Allison, Claudio H. Sibata, Kawana S. White, James A. McCubrey & Richard A. Franklin
Pages: 1022-1030
Published online: 26 May 2006
AbstractforInhibition of the CaM-Kinases augments cell death in response to oxygen radicals and oxygen radical inducing cancer therapies in MCF-7 human breast cancer cells | PDF (581.4 KB)
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Commentary

A role for CaM-Kinases in the cellular response to oxidative stress?
Vasily A. Yakovlev & Ross B. Mikkelsen
Pages: 1031-1032
Published online: 26 May 2006
AbstractforA role for CaM-Kinases in the cellular response to oxidative stress? | PDF (149.2 KB)
  • 187 Views
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Research Paper

Article
Differentiation of normal skin and melanoma using high resolution hyperspectral imaging
David T. Dicker, Jeremy Lerner, Pat Van Belle, DuPont Guerry, 4th, Meenhard Herlyn, David E. Elder & Wafik S. El-Deiry
Pages: 1033-1038
Published online: 26 May 2006
AbstractforDifferentiation of normal skin and melanoma using high resolution hyperspectral imaging | PDF (770.1 KB)
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Commentary

Chemokine signaling in gliomas: Prognostic factor, Therapeutic target or both?
Ian Krop
Pages: 1039-1041
Published online: 26 May 2006
AbstractforChemokine signaling in gliomas: Prognostic factor, Therapeutic target or both? | PDF (178.2 KB)
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Profiles and Legacies

Editorial
The gift of being first-generation American
Victoria L. Seewaldt
Pages: 1042-1045
Published online: 26 May 2006
AbstractforThe gift of being first-generation American | PDF (196.1 KB)
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