Cancer Biology & Therapy, Volume 6, Issue 12 (2007)

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Cancer Biology & Therapy, Volume 6, Issue 12 (2007)

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Editor's Corner

Editorial
Cover Image
Page: i
Published online: 01 Dec 2007
AbstractforCover Image | PDF (690.2 KB)
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News

News
Genome study charts genetic landscape of lung cancer
Pages: 1831-1832
Published online: 01 Dec 2007
AbstractforGenome study charts genetic landscape of lung cancer | PDF (343.2 KB)
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News
SUMO wrestles SENP1 over response to hypoxia, providing possible cancer targets: research under way on agent to stop SENP1 protein and strangle tumors
Page: 1831
Published online: 01 Dec 2007
AbstractforSUMO wrestles SENP1 over response to hypoxia, providing possible cancer targets: research under way on agent to stop SENP1 protein and strangle tumors | PDF (343.2 KB)
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News
Drug combination effective against multiple myeloma: NEJM study shows lenalidomide-dexamethasone slows disease
Pages: 1831-1832
Published online: 01 Dec 2007
AbstractforDrug combination effective against multiple myeloma: NEJM study shows lenalidomide-dexamethasone slows disease | PDF (343.2 KB)
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News
Cancer gene drives pivotal decision in early brain development
Pages: 1831-1832
Published online: 01 Dec 2007
AbstractforCancer gene drives pivotal decision in early brain development | PDF (343.2 KB)
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News
Immune system can drive cancers into dormant state
Pages: 1831-1832
Published online: 01 Dec 2007
AbstractforImmune system can drive cancers into dormant state | PDF (343.2 KB)
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News
Cancer drug works by overactivating cancer gene: melanoma tumors carry enemy within, suggesting new treatment strategy
Page: 1831
Published online: 01 Dec 2007
AbstractforCancer drug works by overactivating cancer gene: melanoma tumors carry enemy within, suggesting new treatment strategy | PDF (343.2 KB)
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News
Oral drug sets new survival standard for bone marrow cancer: Abramson Cancer Center participates in landmark Phase III study for myeloma treatment
Page: 1831
Published online: 01 Dec 2007
AbstractforOral drug sets new survival standard for bone marrow cancer: Abramson Cancer Center participates in landmark Phase III study for myeloma treatment | PDF (343.2 KB)
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News
Cleveland BioLabs launches Phase II advanced renal cell carcinoma trial for Curaxin CBLC102
Page: 1831
Published online: 01 Dec 2007
AbstractforCleveland BioLabs launches Phase II advanced renal cell carcinoma trial for Curaxin CBLC102 | PDF (343.2 KB)
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Review

Review Article
New enlightenment of French paradox: Resveratrol's potential for cancer chemoprevention and anti-cancer therapy
Bo-lin Liu, Xiang Zhang, Wei Zhang & Hai-ning Zhen
Pages: 1833-1836
Published online: 01 Dec 2007
AbstractforNew enlightenment of French paradox: Resveratrol's potential for cancer chemoprevention and anti-cancer therapy | PDF (135.5 KB)
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Journal Club

ATM prevents unattended DNA double strand breaks on site and in generations to come
Bu Yin, Velibor Savic & Craig H. Bassing
Pages: 1837-1839
Published online: 01 Dec 2007
AbstractforATM prevents unattended DNA double strand breaks on site and in generations to come | PDF (536.5 KB)
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Clinical Study

Article
Expression of dystroglycan correlates with tumor grade and predicts survival in renal cell carcinoma
A. Sgambato, A. Camerini, D. Amoroso, G. Genovese, F. De Luca, M. Cecchi, M. Migaldi, A. Rettino, C. Valsuani, G. Tartarelli, S. Donati, O. Siclari, G. Rossi & A. Cittadini
Pages: 1840-1846
Published online: 01 Dec 2007
AbstractforExpression of dystroglycan correlates with tumor grade and predicts survival in renal cell carcinoma | PDF (1.2 MB)
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Clinical Trials

Article
1E10 anti-idiotype vaccine in non-small cell lung cancer: Experience in stage IIIb/IV patients.
S. Alfonso, R.M. Díaz, A. de la Torre, E. Santiesteban, F. Aguirre, K. Pérez, J.L. Rodríguez, M.C. Barroso, A.M. Hernández, D. Toledo, M.R. Gabri, D.F. Alonso, Carmen Viada, R.E. Gómez, E. Pestana, Eduardo Suarez, A.M. Vázquez, R. Perez & A. Macías
Pages: 1847-1852
Published online: 01 Dec 2007
Abstractfor1E10 anti-idiotype vaccine in non-small cell lung cancer: Experience in stage IIIb/IV patients. | PDF (551.5 KB)
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Brief Communication

Brief Report
BRCA1 regulates γ-tubulin binding to centrosomes
Satish Sankaran, Donna E. Crone, Robert E. Palazzo & Jeffrey D. Parvin
Pages: 1853-1857
Published online: 01 Dec 2007
AbstractforBRCA1 regulates γ-tubulin binding to centrosomes | PDF (620.5 KB)
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Brief Report
Microarray analysis of p53-dependent gene expression in response to hypoxia and DNA damage
Paul G. Corn & Wafik S. El-Deiry
Pages: 1858-1866
Published online: 01 Dec 2007
AbstractforMicroarray analysis of p53-dependent gene expression in response to hypoxia and DNA damage | PDF (412 KB)
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Clinical Case Report

Case Report
Primary cardiac lymphoma: Utility of multimodality imaging in diagnosis and management
A.R. Mato, A.K. Morgans, M. Roullet, A. Bagg, E. Glatstein, H.I Litt, L.H. Downs, E.A. Chong, E.R. Olson, C. Andreadis & S.J. Schuster
Pages: 1867-1870
Published online: 01 Dec 2007
AbstractforPrimary cardiac lymphoma: Utility of multimodality imaging in diagnosis and management | PDF (585 KB)
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Research Paper

Article
Study of immunotherapy of murine myeloma by an IL-21-based tumor vaccine in BALB/C mice
Jun Dou, Lili Chu, Fengshu Zhao, Quan Tang, Aifeng Zhang, Lanfang Zhang, Yongfang Wang, Yating Li, Minggang Cao & Ning Gu
Pages: 1871-1879
Published online: 01 Dec 2007
AbstractforStudy of immunotherapy of murine myeloma by an IL-21-based tumor vaccine in BALB/C mice | PDF (899.7 KB)
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Article
Alteration of glyoxalases gene expression in response to testosterone in LNCaP and PC3 human prostate cancer cells
Cinzia Antognelli, Chiara Del Buono, Francesca Baldracchini, Vincenzo Talesa, Emanuele Cottini, Celestino Brancadoro, Alessandro Zucchi & Ettore Mearini
Pages: 1880-1888
Published online: 01 Dec 2007
AbstractforAlteration of glyoxalases gene expression in response to testosterone in LNCaP and PC3 human prostate cancer cells | PDF (1.5 MB)
  • 484 Views
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Article
Development of novel chimeric transmembrane proteins for multimodality imaging of cancer cells
Paul T. Winnard, Jessica B. Kluth, Y Kato, D Artemov & Venu Raman
Pages: 1889-1899
Published online: 01 Dec 2007
AbstractforDevelopment of novel chimeric transmembrane proteins for multimodality imaging of cancer cells | PDF (776.8 KB)
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Article
Inhibition of Stat3 activity by YC-1 enhances chemo-sensitivity in hepatocellular carcinoma
Chi Keung Lau, Zhen Fan Yang, Shuk Pik Lam, Chi Tat Lam, Patricia Ngai, Ka Ho Tam, Ronnie Tung-Ping Poon & Sheung-Tat Fan
Pages: 1900-1907
Published online: 01 Dec 2007
AbstractforInhibition of Stat3 activity by YC-1 enhances chemo-sensitivity in hepatocellular carcinoma | PDF (685 KB)
  • 625 Views
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Article
AMPA antagonists inhibit the extracellular signal regulated kinase pathway and suppress lung cancer growth
Andrzej Stepulak, Marco Sifringer, Wojciech Rzeski, Katja Brocke, Alexander Gratopp, Elena E. Pohl, Lechoslaw Turski & Chrysanthy Ikonomidou
Pages: 1908-1915
Published online: 01 Dec 2007
AbstractforAMPA antagonists inhibit the extracellular signal regulated kinase pathway and suppress lung cancer growth | PDF (575.4 KB)
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Article
Generation of Her-2/neu vaccine utilizing idiotypic network cascade
Smarajit Pal, Asim Saha, Kartik Mohanty, Palash Mallick, Sunil K. Chatterjee, Kenneth A. Foon & Malaya Bhattacharya-Chatterjee
Pages: 1916-1925
Published online: 01 Dec 2007
AbstractforGeneration of Her-2/neu vaccine utilizing idiotypic network cascade | PDF (461.8 KB)
  • 267 Views
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Article
SEPT9_V1 protein expression is associated with human cancer cell resistance to microtubule disrupting agents
Sharon Amir & Nicola J. Mabjeesh
Pages: 1926-1931
Published online: 01 Dec 2007
AbstractforSEPT9_V1 protein expression is associated with human cancer cell resistance to microtubule disrupting agents | PDF (357.2 KB)
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Article
Contribution of dendritic cells FcγRI and FcγRIII to cross-presentation of tumor cells opsonized with the anti-MHC class I monoclonal antibodies
Elena Signorino, Davide Brusa, Riccarda Granata, Fabio Malavasi, Soldano Ferrone & Lina Matera
Pages: 1932-1937
Published online: 01 Dec 2007
AbstractforContribution of dendritic cells FcγRI and FcγRIII to cross-presentation of tumor cells opsonized with the anti-MHC class I monoclonal antibodies | PDF (512.6 KB)
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Article
Green tea polyphenol and epigallocatechin gallate induce apoptosis and inhibit invasion in human breast cancer cells
Rajesh L. Thangapazham, Neena Passi & Radha K. Maheshwari
Pages: 1938-1943
Published online: 01 Dec 2007
AbstractforGreen tea polyphenol and epigallocatechin gallate induce apoptosis and inhibit invasion in human breast cancer cells | PDF (337.7 KB)
  • 912 Views
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Article
Erythropoietin reduces cisplatin-induced apoptosis in renal carcinoma cells via a PKC dependent pathway
J. Li, D.A. Vesey, D.W. Johnson & G. C. Gobe
Pages: 1944-1950
Published online: 01 Dec 2007
AbstractforErythropoietin reduces cisplatin-induced apoptosis in renal carcinoma cells via a PKC dependent pathway | PDF (379.7 KB)
  • 417 Views
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Article
PDGF BB induces VEGF secretion in ovarian cancer
Daniela Matei, Stephanie Kelich, Liyun Cao, Nancy Menning, Robert E. Emerson, Jyiannu Rao, Meei Huey Jeng & George W. Sledge
Pages: 1951-1959
Published online: 01 Dec 2007
AbstractforPDGF BB induces VEGF secretion in ovarian cancer | PDF (504.5 KB)
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Article
Controlled internalization of Her-2/neu receptors by cross-linking for targeted delivery
Wenlian Zhu, Baasil Okollie & Dmitri Artemov
Pages: 1960-1966
Published online: 01 Dec 2007
AbstractforControlled internalization of Her-2/neu receptors by cross-linking for targeted delivery | PDF (576.2 KB)
  • 2034 Views
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Article
PPARgamma-Active triterpenoid CDDO enhances ATRA-induced differentiation in APL
Yoko Tabe, Marina Konopleva, Yutaka Kondo, Rooha Contractor, Twee Tsao, Sergej Konoplev, Yuexi Shi, Xiaoyang Ling, Julie C. Watt, Yuko Tsutsumi-Ishii, Akimichi Ohsaka, Isao Nagaoka, Jean-Pierre Issa, Scott C. Kogan & Michael Andreeff
Pages: 1967-1977
Published online: 01 Dec 2007
AbstractforPPARgamma-Active triterpenoid CDDO enhances ATRA-induced differentiation in APL | PDF (1,020.1 KB)
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Article
Regulation and pharmacokinetics of inducible recombinant TRAIL expression
Aiwen Dong, Jie Hu, Lili Zhao, Huiling Xu & Xinyuan Liu
Pages: 1978-1985
Published online: 01 Dec 2007
AbstractforRegulation and pharmacokinetics of inducible recombinant TRAIL expression | PDF (518.1 KB)
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Article
TRAF4 is potently induced by TAp63 isoforms and localised according to differentiation in SCCHN
Xiaolian Gu, Philip J. Coates, Stephanie F. MacCallum, Linda Boldrup, Björn Sjöström & Karin Nylander
Pages: 1986-1990
Published online: 01 Dec 2007
AbstractforTRAF4 is potently induced by TAp63 isoforms and localised according to differentiation in SCCHN | PDF (331.9 KB)
  • 314 Views
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Article
Differential lysis of tumors by polyclonal T cell lines and T cell clones specific for hTERT
Dih-Yih Chen, Barbara A. Vance, Lara B. S. Thompson, Susan M. Domchek & Robert H. Vonderheide
Pages: 1991-1996
Published online: 01 Dec 2007
AbstractforDifferential lysis of tumors by polyclonal T cell lines and T cell clones specific for hTERT | PDF (340 KB)
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Article
Expression of immune-related molecules in primary EBV positive chinese nasopharyngeal carcinoma: Associated with latent membrane protein 1 (LMP1) expression
Jiang Li, Xiao-shi Zhang, Dan Xie, Hai-xia Deng, Yan-fang Gao, Qiu-yan Chen, Wen-lin Huang, Maria G. Masucci & Yi-Xin Zeng
Pages: 1997-2004
Published online: 01 Dec 2007
AbstractforExpression of immune-related molecules in primary EBV positive chinese nasopharyngeal carcinoma: Associated with latent membrane protein 1 (LMP1) expression | PDF (711 KB)
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Article
Coix seed extract, A commonly used treatment for cancer in china, inhibits NFκB and protein kinase C signaling
Ju-Hyung Woo, Li Dapeng, Li Dapeng, Hajime Orita, Jonathan Coulter, Ellen Tully, Taeg Kyu Kwon, Shi Xu & Edward Gabrielson
Pages: 2005-2011
Published online: 01 Dec 2007
AbstractforCoix seed extract, A commonly used treatment for cancer in china, inhibits NFκB and protein kinase C signaling | PDF (699.1 KB)
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