Cancer Biology & Therapy, Volume 6, Issue 1 (2007)

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Cancer Biology & Therapy, Volume 6, Issue 1 (2007)

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Editor's Corner

Editorial
Cover Image
Page: i
Published online: 01 Jan 2007
AbstractforCover Image | PDF (1.4 MB)
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Editorial
Cancer Biology & Therapy Celebrates Five Years of Publication
Wafik S. El-Deiry
Pages: 9-10
Published online: 01 Jan 2007
AbstractforCancer Biology & Therapy Celebrates Five Years of Publication | PDF (323 KB)
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News

News
Bortezomib and Lenalidomide effective in Myeloma
Pages: 11-10
Published online: 01 Jan 2007
AbstractforBortezomib and Lenalidomide effective in Myeloma | PDF (225.5 KB)
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News
Beneficial Effects of Estrogen in Colon Cancer
Pages: 11-10
Published online: 01 Jan 2007
AbstractforBeneficial Effects of Estrogen in Colon Cancer | PDF (225.5 KB)
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News
Maternal Diet and Risk of Cancer in Offspring
Pages: 11-10
Published online: 01 Jan 2007
AbstractforMaternal Diet and Risk of Cancer in Offspring | PDF (225.5 KB)
  • 112 Views
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News
Targeting Glioblastoma Stem Cells with BMP4
Pages: 11-10
Published online: 01 Jan 2007
AbstractforTargeting Glioblastoma Stem Cells with BMP4 | PDF (225.5 KB)
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News
Levels of NAC-1 May Predict Recurrence of Ovarian Cancer
Pages: 11-10
Published online: 01 Jan 2007
AbstractforLevels of NAC-1 May Predict Recurrence of Ovarian Cancer | PDF (225.5 KB)
  • 196 Views
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News
iHOP, A New Gene and Protein Analysis Tool
Pages: 11-10
Published online: 01 Jan 2007
AbstractforiHOP, A New Gene and Protein Analysis Tool | PDF (225.5 KB)
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News
Lapatinib Shows Promise for Inflammatory Breast Cancer
Pages: 11-10
Published online: 01 Jan 2007
AbstractforLapatinib Shows Promise for Inflammatory Breast Cancer | PDF (225.5 KB)
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News
Cromolyn, an Allergy Drug, Inhibits Pancreatic Cancer in Animal Models
Pages: 11-10
Published online: 01 Jan 2007
AbstractforCromolyn, an Allergy Drug, Inhibits Pancreatic Cancer in Animal Models | PDF (225.5 KB)
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News
Bortezomib Plus Doxorubicin Combination Slows Progression of Multiple Myeloma
Pages: 11-10
Published online: 01 Jan 2007
AbstractforBortezomib Plus Doxorubicin Combination Slows Progression of Multiple Myeloma | PDF (225.5 KB)
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News
T-Regulatory Cells Predict Recurrence in Lung Cancer Patients
Pages: 11-10
Published online: 01 Jan 2007
AbstractforT-Regulatory Cells Predict Recurrence in Lung Cancer Patients | PDF (225.5 KB)
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Review

Review Article
Colorectal cancer: New advances in immunotherapy
Rafael Cubas, Min Li, Changyi Chen & Qizhi Yao
Pages: 11-17
Published online: 01 Jan 2007
AbstractforColorectal cancer: New advances in immunotherapy | PDF (446 KB)
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Clinical Case Report

Case Report
Evidence of myeloid differentiation in non-M3 acute myeloid leukemia treated with the retinoid X receptor agonist bexarotene
Donald E. Tsai, Selina Luger, Allison Kemner, Cezary Swider, Ami Goradia, Ewa Tomczak, Doris DiPatri, Adam Bagg, Peter Nowell, Alison W. Loren, Alexander Perl, Stephen Schuster, James E. Thompson, David Porter, Charlambos Andreadis, Edward A. Stadtmauer, Steven Goldstein, Richard Ghalie & Martin Carroll
Pages: 18-21
Published online: 01 Jan 2007
AbstractforEvidence of myeloid differentiation in non-M3 acute myeloid leukemia treated with the retinoid X receptor agonist bexarotene | PDF (599.2 KB)
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Clinical Trials

Article
Diagnostic efficacy and safety of 99mTc-Labeled monoclonal antibody ior c5 in patients with colorectal and anal carcinomas: Final report clinical trial phase I/II
Mayra Ramos-Suzarte, Alejandro Perera Pintado, Nelson Rodríguez Mesa, Juan P. Oliva, Normando Iznaga-Escobar, Leonel T. Aroche, Gilmara Pimentel, Joaquín González, Maria Cordero, Obaya T. Rodríguez, Ramos T. Crombet & R. Perez
Pages: 22-29
Published online: 01 Jan 2007
AbstractforDiagnostic efficacy and safety of 99mTc-Labeled monoclonal antibody ior c5 in patients with colorectal and anal carcinomas: Final report clinical trial phase I/II | PDF (1,009.5 KB)
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Research Paper

Article
Differential activity of sulindac metabolites against squamous cell carcinoma of the head and neck is mediated by p21waf1/cip1 induction and cell cycle inhibition
Jonathan M Bock, Sarita G Menon, Prabhat C Goswami, Lori L Sinclair, Nichole S Bedford, Robert E Jackson & Douglas K Trask
Pages: 30-39
Published online: 01 Jan 2007
AbstractforDifferential activity of sulindac metabolites against squamous cell carcinoma of the head and neck is mediated by p21waf1/cip1 induction and cell cycle inhibition | PDF (768.7 KB)
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Article
Expression of TMPRSS2:ERG gene fusion in prostate cancer cells is an important prognostic factor for cancer progression
Robert K Nam, Linda Sugar, Zhenghui Wang, Wenyi Yang, Richard Kitching, Laurence H. Klotz, Vasundara Venkateswaran, Steven A. Narod & Arun Seth
Pages: 40-45
Published online: 01 Jan 2007
AbstractforExpression of TMPRSS2:ERG gene fusion in prostate cancer cells is an important prognostic factor for cancer progression | PDF (668.8 KB)
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Commentary

TMPRSS2:ERG gene fusion: A new genetic marker for prostate cancer progression
Marcella Macaluso & Antonio Giordano
Pages: 46-47
Published online: 01 Jan 2007
AbstractforTMPRSS2:ERG gene fusion: A new genetic marker for prostate cancer progression | PDF (211.3 KB)
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Research Paper

Article
In vitro comparison of the vitamin D endocrine system in 1,25(OH)2D3-responsive and –Resistant melanoma cells
Jörg Reichrath, Martin Rech, Maryam Moeini, Eckart Meese, Wolfgang Tilgen & Markus Seifert
Pages: 48-55
Published online: 01 Jan 2007
AbstractforIn vitro comparison of the vitamin D endocrine system in 1,25(OH)2D3-responsive and –Resistant melanoma cells | PDF (798.6 KB)
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Article
Quercetin, Siamois 1 and siamois 2 induce apoptosis in human breast cancer MDA-MB-435 cells xenograft in vivo
Samarn Dechsupa, Suchart Kothan, Jackie Vergote, Gerard Leger, Antoine Martineau, Simone Beranger, Rachian Kosanlavit, Jean-Luc Moretti & Samlee Mankhetkorn
Pages: 56-61
Published online: 01 Jan 2007
AbstractforQuercetin, Siamois 1 and siamois 2 induce apoptosis in human breast cancer MDA-MB-435 cells xenograft in vivo | PDF (920.6 KB)
  • 634 Views
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Commentary

Polyphenols in breast cancer treatment
Richard A. Franklin & James A. McCubrey
Pages: 62-63
Published online: 01 Jan 2007
AbstractforPolyphenols in breast cancer treatment | PDF (343.7 KB)
  • 235 Views
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Research Paper

Article
Histone deacetylase inhibitor LBH589 reactivates silenced estrogen receptor alpha (ER) gene expression without loss of DNA hypermethylation
Qun Zhou, Peter Atadja & Nancy E. Davidson
Pages: 64-69
Published online: 01 Jan 2007
AbstractforHistone deacetylase inhibitor LBH589 reactivates silenced estrogen receptor alpha (ER) gene expression without loss of DNA hypermethylation | PDF (692.3 KB)
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Article
Detecting changes in tumor hypoxia with carbonic anhydrase IX and pimonidazole
Kyung Hwan Shin, Juan A Diaz-Gonzalez, James Russell, Qing Chen, Paul Burgman, Xiao-Feng Li & C. Cliffton Ling
Pages: 70-75
Published online: 01 Jan 2007
AbstractforDetecting changes in tumor hypoxia with carbonic anhydrase IX and pimonidazole | PDF (835.8 KB)
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Article
Profile of Ets gene expression in human breast carcinoma
Jin He, Yong Pan, Jianhua Hu, Constance Albarracin, Yun Wu & Jia Le Dai
Pages: 76-82
Published online: 01 Jan 2007
AbstractforProfile of Ets gene expression in human breast carcinoma | PDF (1.2 MB)
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Commentary

ETS genes in breast cancer: A step in the right direction
Xinyan Wu & Saraswati Sukumar
Pages: 83-84
Published online: 01 Jan 2007
AbstractforETS genes in breast cancer: A step in the right direction | PDF (212 KB)
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Research Paper

Article
Growth inhibitory effects of gastric cancer cells with an increase in S phase and alkaline phosphatase activity repression by aloe-emodin
Junming Guo, Bingxiu Xiao, Shun Zhang, Donghai Liu, Yiping Liao & Qian Sun
Pages: 85-88
Published online: 01 Jan 2007
AbstractforGrowth inhibitory effects of gastric cancer cells with an increase in S phase and alkaline phosphatase activity repression by aloe-emodin | PDF (987.8 KB)
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Commentary

Aloe(-emodin) for cancer? More than just a comforting salve
Jay F. Dorsey & Gary D. Kao
Pages: 89-90
Published online: 01 Jan 2007
AbstractforAloe(-emodin) for cancer? More than just a comforting salve | PDF (208.1 KB)
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Research Paper

Article
Slow acetylator genotype of N-acetyl transferase2 (NAT2) is associated with increased susceptibility to gallbladder cancer; The cancer risk not modulated by gallstone disease
Sachchida N. Pandey, Gourdas Choudhuri, Dinesh R. Modi & Balraj Mittal
Pages: 91-96
Published online: 01 Jan 2007
AbstractforSlow acetylator genotype of N-acetyl transferase2 (NAT2) is associated with increased susceptibility to gallbladder cancer; The cancer risk not modulated by gallstone disease | PDF (585.1 KB)
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Commentary

Predisposed to toxins: Association of gallbladder cancer with N-acetyl transferase SNPs
Justin L. Mott & Gregory J. Gores
Pages: 97-98
Published online: 01 Jan 2007
AbstractforPredisposed to toxins: Association of gallbladder cancer with N-acetyl transferase SNPs | PDF (396.9 KB)
  • 249 Views
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Research Paper

Article
PPARγ ligands enhance TRAIL-induced apoptosis through DR5 upregulation and c-FLIP downregulation in human lung cancer cells
Wei Zou, Xiangguo Liu, Ping Yue, Fadlo R. Khuri & Shi-Yong Sun
Pages: 99-106
Published online: 01 Jan 2007
AbstractforPPARγ ligands enhance TRAIL-induced apoptosis through DR5 upregulation and c-FLIP downregulation in human lung cancer cells | PDF (818.4 KB)
  • 325 Views
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Commentary

PPARγ agonists follow an unknown TRAIL in lung cancer
Stanley Lipkowitz & Phillip A. Dennis
Pages: 107-109
Published online: 01 Jan 2007
AbstractforPPARγ agonists follow an unknown TRAIL in lung cancer | PDF (352.2 KB)
  • 142 Views
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"D" approach to prevent metastasis
Lucia R. Languino & Vivek Rangnekar
Pages: 110-111
Published online: 01 Jan 2007
Abstractfor"D" approach to prevent metastasis | PDF (343 KB)
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Predicting response to EGFR-tyrosine kinase inhibitors among diverse ancestries: Just way too polymorphic
Kevin M. Zbuk & Charis Eng
Pages: 112-115
Published online: 01 Jan 2007
AbstractforPredicting response to EGFR-tyrosine kinase inhibitors among diverse ancestries: Just way too polymorphic | PDF (404.3 KB)
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The p53 family: Prospect for cancer gene therapy
Jin Zhang & Xinbin Chen
Pages: 116-118
Published online: 01 Jan 2007
AbstractforThe p53 family: Prospect for cancer gene therapy | PDF (400.3 KB)
  • 158 Views
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Is ERK activation a good biomarker for estradiol and tamoxifen effects?
Keiran S.M. Smalley & Keith T. Flaherty
Pages: 119-120
Published online: 01 Jan 2007
AbstractforIs ERK activation a good biomarker for estradiol and tamoxifen effects? | PDF (357.9 KB)
  • 264 Views
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Targeting PECAM-1 for anti-cancer therapy
Horace M. DeLisser
Pages: 121-122
Published online: 01 Jan 2007
AbstractforTargeting PECAM-1 for anti-cancer therapy | PDF (182.2 KB)
  • 400 Views
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Reg IV can serve for early diagnosis and therapy
Irene Pankova-Kholmyansky & Nadir Arber
Pages: 123-124
Published online: 01 Jan 2007
AbstractforReg IV can serve for early diagnosis and therapy | PDF (368.8 KB)
  • 148 Views
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The role of CD44 in HNSCC
Aaron D. Nelson & Jennifer Grandis
Pages: 125-126
Published online: 01 Jan 2007
AbstractforThe role of CD44 in HNSCC | PDF (220.2 KB)
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