Cancer Biology & Therapy, Volume 7, Issue 9 (2008)

Browse this journal
Sample our Bioscience journals, sign in here to start your access, Latest two full volumes FREE to you for 14 days

Cancer Biology & Therapy, Volume 7, Issue 9 (2008)

See all volumes and issues
Vol 25, 2024 Vol 24, 2023 Vol 23, 2022 Vol 22, 2021 Vol 21, 2020 Vol 20, 2019 Vol 19, 2018 Vol 18, 2017 Vol 17, 2016 Vol 16, 2015 Vol 15, 2014 Vol 14, 2013 Vol 13, 2012 Vol 12, 2011 Vol 11, 2011 Vol 10, 2010 Vol 9, 2010 Vol 8, 2009 Volume 7, 2008 Vol 6, 2007 Vol 5, 2006 Vol 4, 2005 Vol 3, 2004 Vol 2, 2003 Vol 1, 2002
Download citations Download PDFs Download issue

Editor's Corner

Editorial
Cover caption
Page: i
Published online: 01 Sep 2008
AbstractforCover caption | PDF (38.1 MB)
  • 119 Views
  • 0 CrossRef citations
  • 0Altmetric
Free Access

Review: Focus on Glioblastoma

Review Article
PTEN Signaling pathways in glioblastoma
Dimpy Koul
Pages: 1321-1325
Published online: 01 Sep 2008
AbstractforPTEN Signaling pathways in glioblastoma | PDF (247.1 KB)
  • 2393 Views
  • 155 CrossRef citations
  • 0Altmetric
Free Access
Review Article
Epigenetic changes in gliomas
Rebecca Burgess, Robert Jenkins & Zhiguo Zhang
Pages: 1326-1334
Published online: 01 Sep 2008
AbstractforEpigenetic changes in gliomas | PDF (714.4 KB)
  • 308 Views
  • 23 CrossRef citations
  • 0Altmetric
Free Access
Review Article
Searching for a cure: Gene therapy for glioblastoma
Paul Dent, Adly Yacoub, Margaret Park, Devanand Sarkar, Khalid Shah, David T. Curiel, Steven Grant & Paul B. Fisher
Pages: 1335-1340
Published online: 01 Sep 2008
AbstractforSearching for a cure: Gene therapy for glioblastoma | PDF (200.6 KB)
  • 368 Views
  • 16 CrossRef citations
  • 0Altmetric
Free Access
Review Article
Gene delivery by embryonic stem cells for malignant glioma therapy: hype or hope?
Isabelle M. Germano, Mahmud Uzzaman & Gordon Keller
Pages: 1341-1347
Published online: 01 Sep 2008
AbstractforGene delivery by embryonic stem cells for malignant glioma therapy: hype or hope? | PDF (953.7 KB)
  • 237 Views
  • 12 CrossRef citations
  • 0Altmetric
Open Access

Commentary

Fibroblasts act as co-conspirators for chemotherapy resistance
Derek C. Radisky
Pages: 1348-1349
Published online: 01 Sep 2008
AbstractforFibroblasts act as co-conspirators for chemotherapy resistance | PDF (267.5 KB)
  • 184 Views
  • 5 CrossRef citations
  • 0Altmetric
Free Access

Journal Club

Concealed cargo within the tumor microenvironment: Microvesicles disseminate oncogenic receptors among cancer cells
Roddy O'Connor
Pages: 1350-1351
Published online: 01 Sep 2008
CitationforConcealed cargo within the tumor microenvironment: Microvesicles disseminate oncogenic receptors among cancer cells | PDF (100.6 KB)
  • 157 Views
  • 1 CrossRef citations
  • 0Altmetric
Free Access

Clinical Study

Article
Hypoxia-inducible proto-oncogene Pim-1 is a prognostic marker in pancreatic ductal adenocarcinoma
Carolin Reiser-Erkan, Mert Erkan, Zheng Pan, Sandor Bekasi, Nathalia A. Giese, Sylvia Streit, Christoph W. Michalski, Helmut Friess & Jörg Kleeff
Pages: 1352-1359
Published online: 01 Sep 2008
AbstractforHypoxia-inducible proto-oncogene Pim-1 is a prognostic marker in pancreatic ductal adenocarcinoma | PDF (2.6 MB)
  • 598 Views
  • 80 CrossRef citations
  • 0Altmetric
Free Access

Commentary

Prognostic markers in pancreatic ductal adenocarcinomas
Aram F. Hezel & Nabeel Bardeesy
Pages: 1360-1361
Published online: 01 Sep 2008
AbstractforPrognostic markers in pancreatic ductal adenocarcinomas | PDF (95.4 KB)
  • 173 Views
  • 5 CrossRef citations
  • 0Altmetric
Free Access

Research Paper

Article
Granulocyte activity in patients with cancer and healthy subjects
Nina A. Mikirova, Arkady A. Klykov, James A. Jackson & Neil H. Riordan
Pages: 1362-1367
Published online: 01 Sep 2008
AbstractforGranulocyte activity in patients with cancer and healthy subjects | PDF (789.4 KB)
  • 263 Views
  • 9 CrossRef citations
  • 0Altmetric
Free Access
Article
Apoptin induces apoptosis in an oral cancer mouse model
Remilio A. L. Schoop, Robert J. Baatenburg de Jong & Mathieu H. M. Noteborn
Pages: 1368-1373
Published online: 01 Sep 2008
AbstractforApoptin induces apoptosis in an oral cancer mouse model | PDF (574.7 KB)
  • 310 Views
  • 19 CrossRef citations
  • 0Altmetric
Free Access

Commentary

Viral proteins killing tumor cells: New weapons in the fight against cancer
Jürg P.F. Nüesch, Séverine Bär & Jean Rommelaere
Pages: 1374-1376
Published online: 01 Sep 2008
AbstractforViral proteins killing tumor cells: New weapons in the fight against cancer | PDF (265.6 KB)
  • 209 Views
  • 9 CrossRef citations
  • 0Altmetric
Free Access

Research Paper

Article
Everolimus (RAD001) and anti-angiogenic cyclophosphamide show long-term control of gastric cancer growth in vivo
Daniel Cejka, Matthias Preusser, Adelheid Woehrer, Wolfgang Sieghart, Sabine Strommer, Johannes Werzowa, Thorsten Fuereder & Volker Wacheck
Pages: 1377-1385
Published online: 01 Sep 2008
AbstractforEverolimus (RAD001) and anti-angiogenic cyclophosphamide show long-term control of gastric cancer growth in vivo | PDF (998.4 KB)
  • 534 Views
  • 56 CrossRef citations
  • 0Altmetric
Free Access

Commentary

Combining mTOR inhibition with metronomic chemotherapy in targeting angiogenesis
Cindy H. Chau, Weixin Wang & William D. Figg
Pages: 1386-1387
Published online: 01 Sep 2008
AbstractforCombining mTOR inhibition with metronomic chemotherapy in targeting angiogenesis | PDF (100.9 KB)
  • 173 Views
  • 3 CrossRef citations
  • 0Altmetric
Free Access

Research Paper

Article
Aurora A, Aurora B and survivin are novel targets of transcriptional regulation by histone deacetylase inhibitors in non-small cell lung cancer
Xu-Hui Zhang, Mahadev Rao, Joseph A. Loprieato, Julie A. Hong, Ming Zhao, Guo-Zhu Chen, Ashley E. Humphries, Dao M. Nguyen, Jane B. Trepel, Xiaodan Yu & David S. Schrump
Pages: 1388-1397
Published online: 01 Sep 2008
AbstractforAurora A, Aurora B and survivin are novel targets of transcriptional regulation by histone deacetylase inhibitors in non-small cell lung cancer | PDF (1.9 MB)
  • 853 Views
  • 44 CrossRef citations
  • 0Altmetric
Open Access
Article
Quantitative promoter hypermethylation profiles of ductal carcinoma in situ in North American and Korean women: Potential applications for diagnosis
Ji Shin Lee, Mary Jo Fackler, Wei Wen Teo, Jae Hyuk Lee, Chan Choi, Min Ho Park, Jung Han Yoon, Zhe Zhang, Pedram Argani & Saraswati Sukumar
Pages: 1398-1406
Published online: 01 Sep 2008
AbstractforQuantitative promoter hypermethylation profiles of ductal carcinoma in situ in North American and Korean women: Potential applications for diagnosis | PDF (993 KB)
  • 261 Views
  • 15 CrossRef citations
  • 0Altmetric
Free Access
Article
Platinums sensitize human epithelial tumor cells to lymphotoxin α by inhibiting NF-κB-dependent transcription
Yijun Shen, Jing Wang, Tong Yang, Yuhong Li, Wenqi Jiang, Zhongzhen Guan, Zheng Wang, Jingwei Tan, Jinsong Wu, Gang Li, Qing Xu, Fang Wu, Luochun Wang & Yanjun Liu
Pages: 1407-1414
Published online: 01 Sep 2008
AbstractforPlatinums sensitize human epithelial tumor cells to lymphotoxin α by inhibiting NF-κB-dependent transcription | PDF (3 MB)
  • 319 Views
  • 10 CrossRef citations
  • 0Altmetric
Free Access

Commentary

Raising the price of platinum: Inhibition of NF-κB in human tumor epithelial cells
Catherine E. Wharry & Michael J. May
Pages: 1415-1417
Published online: 01 Sep 2008
AbstractforRaising the price of platinum: Inhibition of NF-κB in human tumor epithelial cells | PDF (378 KB)
  • 118 Views
  • 1 CrossRef citations
  • 0Altmetric
Free Access

Research Paper

Article
Apogossypolone, a nonpeptidic small molecule inhibitor targeting Bcl-2 family proteins, effectively inhibits growth of diffuse large cell lymphoma cells in vitro and in vivo
Yuan Sun, Jack Wu, Amro Aboukameel, Sanjeev Banerjee, Alan A. Arnold, Jianyong Chen, Zaneta Nikolovska-Coleska, Yanqiong Lin, Xiaolan Ling, Dajun Yang, Shaomeng Wang, Ayad Al-Katib & Ramzi M. Mohammad
Pages: 1418-1426
Published online: 01 Sep 2008
AbstractforApogossypolone, a nonpeptidic small molecule inhibitor targeting Bcl-2 family proteins, effectively inhibits growth of diffuse large cell lymphoma cells in vitro and in vivo | PDF (1.8 MB)
  • 230 Views
  • 32 CrossRef citations
  • 0Altmetric
Free Access
Article
Androgen responsive and refractory prostate cancer cells exhibit distinct curcumin regulated transcriptome
Rajesh L. Thangapazham, Syed Shaheduzzaman, Kee-Hong Kim, Neena Passi, Atekelt Tadese, Maryanne Vahey, Albert Dobi, Shiv Srivastava & Radha K. Maheshwari
Pages: 1427-1435
Published online: 01 Sep 2008
AbstractforAndrogen responsive and refractory prostate cancer cells exhibit distinct curcumin regulated transcriptome | PDF (1.3 MB) | Supplemental
  • 598 Views
  • 29 CrossRef citations
  • 0Altmetric
Free Access

Commentary

Prostate cancer and curcumin: Add spice to your life
Bharat B. Aggarwal
Pages: 1436-1440
Published online: 01 Sep 2008
AbstractforProstate cancer and curcumin: Add spice to your life | PDF (609.6 KB)
  • 1170 Views
  • 61 CrossRef citations
  • 0Altmetric
Free Access

Research Paper

Article
Effects of 4E-BP1 expression on hypoxic cell cycle inhibition and tumor cell proliferation and survival
Bryan C. Barnhart, Jennifer C. Lam, Regina M. Young, Peter J. Houghton, Brian Keith & M. Celeste Simon
Pages: 1441-1449
Published online: 01 Sep 2008
AbstractforEffects of 4E-BP1 expression on hypoxic cell cycle inhibition and tumor cell proliferation and survival | PDF (2.7 MB)
  • 346 Views
  • 31 CrossRef citations
  • 0Altmetric
Open Access
Article
Altered expression of organic anion transporter polypeptide (OATP) genes in human breast carcinoma
Katrin Wlcek, Martin Svoboda, Franz Sellner, Georg Krupitza, Walter Jaeger & Theresia Thalhammer
Pages: 1450-1455
Published online: 01 Sep 2008
AbstractforAltered expression of organic anion transporter polypeptide (OATP) genes in human breast carcinoma | PDF (358.1 KB)
  • 725 Views
  • 50 CrossRef citations
  • 0Altmetric
Free Access

Commentary

Can targeting organic anion transporter polypeptide (OATP) genes play a key role in drug therapy
Hiremagalur N. Jayaram & Praveen Kusumanchi
Pages: 1456-1459
Published online: 01 Sep 2008
AbstractforCan targeting organic anion transporter polypeptide (OATP) genes play a key role in drug therapy | PDF (157.7 KB)
  • 264 Views
  • 0 CrossRef citations
  • 0Altmetric
Free Access

Research Paper

Article
The metastasis-associated gene MTA1 is upregulated in advanced ovarian cancer, represses ERβ, and enhances expression of oncogenic cytokine GRO
Christine Dannenmann, Naim Shabani, Klaus Friese, Udo Jeschke, Ioannis Mylonas & Ansgar Brüning
Pages: 1460-1467
Published online: 01 Sep 2008
AbstractforThe metastasis-associated gene MTA1 is upregulated in advanced ovarian cancer, represses ERβ, and enhances expression of oncogenic cytokine GRO | PDF (1.1 MB)
  • 453 Views
  • 60 CrossRef citations
  • 0Altmetric
Free Access

Commentary

MTA1 expression is linked to ovarian cancer
Masanao Murakami, Rajeev Kaul & Erle S. Robertson
Pages: 1468-1470
Published online: 01 Sep 2008
AbstractforMTA1 expression is linked to ovarian cancer | PDF (415.2 KB)
  • 176 Views
  • 3 CrossRef citations
  • 0Altmetric
Free Access

Research Paper

Article
Heat shock induces chromosomal instability in near-tetraploid embryonal carcinoma cells
Rajesh Kumar Gupta & Usha K. Srinivas
Pages: 1471-1480
Published online: 01 Sep 2008
AbstractforHeat shock induces chromosomal instability in near-tetraploid embryonal carcinoma cells | PDF (2.1 MB)
  • 276 Views
  • 16 CrossRef citations
  • 0Altmetric
Free Access
Article
Influence of tetramerisation on site-specific post-translational modifications of p53: comparison of human and murine p53 tumour suppressor protein.
Lorna Jane Warnock, Andrew Alexander Knox, Trevor R. Mee, Sally Anne Raines & Jo Milner
Pages: 1481-1489
Published online: 01 Sep 2008
AbstractforInfluence of tetramerisation on site-specific post-translational modifications of p53: comparison of human and murine p53 tumour suppressor protein. | PDF (1.3 MB)
  • 393 Views
  • 20 CrossRef citations
  • 0Altmetric
Free Access
Article
Downregulation of KSR1 in pancreatic cancer xenografts by antisense oligonucleotides correlates with tumor drug uptake
Jianjun Zhang, Mohammad Zafrullah, Xia Yang, Xianglei Yin, Zhigang Zhang, Zvi Fuks & Richard Kolesnick
Pages: 1490-1495
Published online: 01 Sep 2008
AbstractforDownregulation of KSR1 in pancreatic cancer xenografts by antisense oligonucleotides correlates with tumor drug uptake | PDF (1.6 MB)
  • 240 Views
  • 13 CrossRef citations
  • 0Altmetric
Open Access
Article
Cytoplasmic accumulation of the RNA binding protein HuR is central to tamoxifen resistance in estrogen receptor positive breast cancer cells
Christine Hostetter, Lauren A. Licata, Christina L. Costantino, Agnes Witkiewicz, Charles Yeo, Jonathan R Brody & Judith Clancy Keen
Pages: 1496-1506
Published online: 01 Sep 2008
AbstractforCytoplasmic accumulation of the RNA binding protein HuR is central to tamoxifen resistance in estrogen receptor positive breast cancer cells | PDF (7.8 MB)
  • 636 Views
  • 73 CrossRef citations
  • 0Altmetric
Open Access

Explore articles

Explore the most recently published articles

The predictors of lymphopenia and its effects on survival in locally advanced esophageal squamous cell carcinoma
Danjing Luo et al.
Article | Published online: 1 Jul 2024
Open Access
Neuroendocrine gene subsets are uniquely dysregulated in prostate adenocarcinoma
Nicole M. Naranjo et al.
Article | Published online: 26 Jun 2024
Open Access
Sirtuin1 (sirt1) regulates the glycolysis pathway and decreases cisplatin chemotherapeutic sensitivity to esophageal squamous cell carcinoma
Xuewen Yang et al.
Article | Published online: 12 Jun 2024
Open Access
Effects of combined radiotherapy with immune checkpoint blockade on immunological memory in luminal-like subtype murine bladder cancer model
JiaMin Huang et al.
Article | Published online: 11 Jun 2024
Open Access