Cancer Biology & Therapy, Volume 8, Issue 11 (2009)

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Cancer Biology & Therapy, Volume 8, Issue 11 (2009)

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Editor's Corner

Editorial
Cover caption
Page: i
Published online: 01 Jun 2009
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News

News
Daiichi Sankyo and MorphoSys expand collaboration with two new cancer-related antibody programs
Pages: 987-986
Published online: 01 Jun 2009
AbstractforDaiichi Sankyo and MorphoSys expand collaboration with two new cancer-related antibody programs | PDF (110.4 KB)
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News
Research sheds new light on why pancreatic cancer drugs fail
Pages: 987-986
Published online: 01 Jun 2009
AbstractforResearch sheds new light on why pancreatic cancer drugs fail | PDF (110.4 KB)
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News
M.D. Anderson Study Finds Dramatic Increase in Metastatic Colon Cancer Survival
Pages: 987-986
Published online: 01 Jun 2009
AbstractforM.D. Anderson Study Finds Dramatic Increase in Metastatic Colon Cancer Survival | PDF (110.4 KB)
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News
UNC scientists identify growth factor as possible cancer drug target
Pages: 987-986
Published online: 01 Jun 2009
AbstractforUNC scientists identify growth factor as possible cancer drug target | PDF (110.4 KB)
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News
Landmark UNC-led study finds radiofrequency ablation is effective treatment for Barrett’s esophagus
Pages: 987-986
Published online: 01 Jun 2009
AbstractforLandmark UNC-led study finds radiofrequency ablation is effective treatment for Barrett’s esophagus | PDF (110.4 KB)
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News
Gene Mutation Marks Aggressive Endometrial Cancer
Pages: 987-986
Published online: 01 Jun 2009
AbstractforGene Mutation Marks Aggressive Endometrial Cancer | PDF (110.4 KB)
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Review

Review Article
Regulation of cellular and viral protein expression by the Epstein-Barr virus transcriptional regulator Zta: Implications for therapy of EBV associated tumors
Changguo Chen, Dan Li & Ning Guo
Pages: 987-995
Published online: 01 Jun 2009
Abstractfor Regulation of cellular and viral protein expression by the Epstein-Barr virus transcriptional regulator Zta: Implications for therapy of EBV associated tumors | PDF (308.1 KB)
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Clinical Study

Article
MUC2 but not MUC5 expression correlates with prognosis in radically resected pancreatic cancer patients
Francesco Pantano, Alfonso Baldi, Daniele Santini, Bruno Vincenzi, Domenico Borzomati, Fabio Maria Vecchio, Federica Castri, Armando Antinori, Michele Caraglia, Paolo Magistrelli, Roberto Coppola & Giuseppe Tonini
Pages: 996-999
Published online: 01 Jun 2009
Abstractfor MUC2 but not MUC5 expression correlates with prognosis in radically resected pancreatic cancer patients | PDF (304.8 KB)
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Commentary

MUC2 a new key for pancreas cancer prognosis
Raffaele Addeo, Alberto Abbruzzese & Salvatore Del Prete
Pages: 1000-1001
Published online: 01 Jun 2009
AbstractforMUC2 a new key for pancreas cancer prognosis | PDF (110 KB)
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Research Paper

Article
Inhibitory effects of adenovirus mediated Akt1 and PIK3R1 shRNA on the growth of malignant tumor cells in vitro and in vivo
Yanchao Fu, Qingyu Zhang, Chunsheng Kang, Jing Zhang, Kairu Zhang, Peiyu Pu, Guangxiu Wang & Tao Wang
Pages: 1002-1009
Published online: 01 Jun 2009
Abstractfor Inhibitory effects of adenovirus mediated Akt1 and PIK3R1 shRNA on the growth of malignant tumor cells in vitro and in vivo | PDF (1.5 MB)
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Article
A human bone NOD/SCID mouse model to distinguish metastatic potential in primary breast cancers
Pearl Lam, Wenyi Yang, Yutaka Amemiya, Harriette Kahn, Albert Yee, Claire Holloway & Arun Seth
Pages: 1010-1017
Published online: 01 Jun 2009
AbstractforA human bone NOD/SCID mouse model to distinguish metastatic potential in primary breast cancers | PDF (2.1 MB)
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Article
Down-regulation of LRIG2 expression by RNA interference inhibits glioblastoma cell (GL15) growth, causes cell cycle redistribution, increases cell apoptosis and enhances cell adhesion and invasion in vitro
Baofeng Wang, Lin Han, Rudong Chen, Mingjun Cai, Fuxin Han, Ting Lei & Dong-Sheng Guo
Pages: 1018-1023
Published online: 01 Jun 2009
AbstractforDown-regulation of LRIG2 expression by RNA interference inhibits glioblastoma cell (GL15) growth, causes cell cycle redistribution, increases cell apoptosis and enhances cell adhesion and invasion in vitro | PDF (885.7 KB)
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Commentary

RIGging functional outcomes in glioma cells: New insights into LRIG proteins in malignant gliomas
David D. Eisenstat & Spencer B. Gibson
Pages: 1024-1026
Published online: 01 Jun 2009
AbstractforRIGging functional outcomes in glioma cells: New insights into LRIG proteins in malignant gliomas | PDF (141.5 KB)
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Research Paper

Article
Dual targeting of EphA2 and FAK in ovarian carcinoma
Mian M.K. Shahzad, Chunhua Lu, Jeong-Won Lee, Rebecca L. Stone, Rahul Mitra, Lingegowda S. Mangala, Yiling Lu, Keith A. Baggerly, Christopher G. Danes, Alpa M. Nick, Jyotsnabaran Halder, Hye-Sun Kim, Pablo Vivas-Mejia, Charles N. Landen, Gabriel Lopez-Berestein, Robert L. Coleman & Anil K. Sood
Pages: 1027-1034
Published online: 01 Jun 2009
AbstractforDual targeting of EphA2 and FAK in ovarian carcinoma | PDF (3.8 MB)
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Article
A novel antibody fragment targeting HAb18G/CD147 with cytotoxicity and decreased immunogenicity
Hongbin Zhu, Bin Yang, Xiangmin Yang, Li Wang, Jun Xu, Chenggong Liao, Qiang Feng, Hao Tang, Ling Hu, Zhinan Chen & Yu Li
Pages: 1035-1044
Published online: 01 Jun 2009
AbstractforA novel antibody fragment targeting HAb18G/CD147 with cytotoxicity and decreased immunogenicity | PDF (1.4 MB)
  • 520 Views
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Article
ADAM17 promotes breast cancer cell malignant phenotype through EGFR-PI3K-AKT activation
Xuguang Zheng, Feng Jiang, Mark Katakowski, Zheng Gang Zhang, Qing-e Lu & Michael Chopp
Pages: 1045-1054
Published online: 01 Jun 2009
AbstractforADAM17 promotes breast cancer cell malignant phenotype through EGFR-PI3K-AKT activation | PDF (1.2 MB)
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Commentary

ADAM17: The new face of breast cancer-promoting metalloprotease activity
Kristine Glunde & Ioannis Stasinopoulos
Pages: 1055-1057
Published online: 01 Jun 2009
AbstractforADAM17: The new face of breast cancer-promoting metalloprotease activity | PDF (210.3 KB)
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Research Paper

Article
Inhibiting gastric cancer-associated angiogenesis by CIAPIN1 siRNA
Kun Yan, Li-jie He, Wei Cheng, Zong-zheng Ji, Bin-xiu Zhao, Xiao-li Hui, Shan-shan Cao, Bei Chen, Li He, Shu-hui Lang & Yv Miao
Pages: 1058-1063
Published online: 01 Jun 2009
AbstractforInhibiting gastric cancer-associated angiogenesis by CIAPIN1 siRNA | PDF (525.5 KB)
  • 221 Views
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Article
Downregulated expression of CIAPIN1 may contribute to gastric carcinogenesis by accelerating cell proliferation and promoting cell cycle progression
Zhiming Hao, Xiaohua Li, Taidong Qiao, Shuang Li, Yifei Lv & Daiming Fan
Pages: 1064-1070
Published online: 01 Jun 2009
AbstractforDownregulated expression of CIAPIN1 may contribute to gastric carcinogenesis by accelerating cell proliferation and promoting cell cycle progression | PDF (1.3 MB)
  • 212 Views
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Article
Stromal caveolin-1 levels predict early DCIS progression to invasive breast cancer
Agnieszka K. Witkiewicz, Abhijit Dasgupta, Katherine Nguyen, Chengbao Liu, Albert J. Kovatich, Gordon F. Schwartz, Richard G. Pestell, Federica Sotgia, Hallgeir Rui & Michael P. Lisanti
Pages: 1071-1079
Published online: 01 Jun 2009
AbstractforStromal caveolin-1 levels predict early DCIS progression to invasive breast cancer | PDF (1.8 MB)
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