Cancer Biology & Therapy, Volume 8, Issue 1 (2009)

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Cancer Biology & Therapy, Volume 8, Issue 1 (2009)

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Editor's Corner

Editorial
Cover Caption
Page: i
Published online: 01 Jan 2009
AbstractforCover Caption
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News

News
El-Deiry named as American Cancer Society Research Professor
Pages: 2-3
Published online: 01 Jan 2009
AbstractforEl-Deiry named as American Cancer Society Research Professor | PDF (121.3 KB)
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News
BiPar Sciences presents interim phase 2 results for PARP inhibitor BSI-201 at San Antonio Breast Cancer Symposium
Pages: 2-3
Published online: 01 Jan 2009
AbstractforBiPar Sciences presents interim phase 2 results for PARP inhibitor BSI-201 at San Antonio Breast Cancer Symposium | PDF (121.3 KB)
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News
Two drugs kill resistant melanoma cells in preclinical study
Pages: 2-3
Published online: 01 Jan 2009
AbstractforTwo drugs kill resistant melanoma cells in preclinical study | PDF (121.3 KB)
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News
Roswell Park researchers clarify mechanisms of novel therapy in non-hodgkin's lymphoma cells
Pages: 2-3
Published online: 01 Jan 2009
AbstractforRoswell Park researchers clarify mechanisms of novel therapy in non-hodgkin's lymphoma cells | PDF (121.3 KB)
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Review

Review Article
Pediatric low-grade gliomas and the need for new options for therapy: why and how?
Ibrahim Qaddoumi, Iyad Sultan & Alberto Broniscer
Pages: 4-10
Published online: 01 Jan 2009
AbstractforPediatric low-grade gliomas and the need for new options for therapy: why and how? | PDF (336.4 KB)
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Journal Club

Phenotypic approach to drug discovery
Heather Pressler & W. Douglas Figg
Pages: 11-12
Published online: 01 Jan 2009
CitationforPhenotypic approach to drug discovery | PDF (228.2 KB)
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Clinical Study

Article
Role of recombinant human erythropoietin in patients of advanced cervical cancer treated by chemoradiotherapy
Seema Gupta, Pankaj Kumar Singh, Shyam Singh Bisth, Madan Lal Bhatt, Mohan Chand Pant, Rajeev Gupta, Deepak Gupta, Sharad Singh & M.P.S. Negi
Pages: 13-17
Published online: 01 Jan 2009
AbstractforRole of recombinant human erythropoietin in patients of advanced cervical cancer treated by chemoradiotherapy | PDF (634.8 KB)
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Commentary

Erythropoeisis-Stimulating  Agents (ESAs) in cervix cancer: The “Black Box” paradox
Aparna A. Kamat & Robert L. Coleman
Pages: 18-20
Published online: 01 Jan 2009
AbstractforErythropoeisis-Stimulating  Agents (ESAs) in cervix cancer: The “Black Box” paradox | PDF (213.2 KB)
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Clinical Study

Article
PIK3CA amplification associates with resistance to chemotherapy in ovarian cancer patients
Iwona K. Kolasa, Alina Rembiszewska, Anna Felisiak, Izabela Ziolkowska-Seta, Magdalena Murawska, Joanna Moes, Agnieszka Timorek, Agnieszka Dansonka-Mieszkowska & Jolanta Kupryjanczyk
Pages: 21-26
Published online: 01 Jan 2009
AbstractforPIK3CA amplification associates with resistance to chemotherapy in ovarian cancer patients | PDF (894.8 KB)
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Commentary

PI3K: a rational target for ovarian cancer therapy?
Paul Dent, Steven Grant, Paul B. Fisher & David T. Curiel
Pages: 27-30
Published online: 01 Jan 2009
AbstractforPI3K: a rational target for ovarian cancer therapy? | PDF (261.7 KB)
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Research Paper

Article
Inflammation, but not hypoxia, mediated HIF-1α activation depends on COX-2
Ioannis Stasinopoulos, David R. O'Brien & Zaver M. Bhujwalla
Pages: 31-35
Published online: 01 Jan 2009
AbstractforInflammation, but not hypoxia, mediated HIF-1α activation depends on COX-2 | PDF (470.7 KB)
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Article
Genomewide mRNA profiling of esophageal squamous cell carcinoma for identification of cancer biomarkers
Manoj K. Kashyap, Arivusudar Marimuthu, Charles Jacob Harrys Kishore, Suraj Peri, Shivakumar Keerthikumar, Thotterthodi Subrahmanya Keshava Prasad, Riaz Mahmood, Sudha Rao, Prathibha Ranganathan, Ravinder C. Sanjeeviah, M. Vijayakumar, K. V. Veerendra Kumar, Elizabeth A. Montgomery, Rekha V. Kumar & Akhilesh Pandey
Pages: 36-46
Published online: 01 Jan 2009
AbstractforGenomewide mRNA profiling of esophageal squamous cell carcinoma for identification of cancer biomarkers | PDF (3.9 MB)
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Article
Dietary flaxseed prevents radiation-induced oxidative lung damage, inflammation and fibrosis in a mouse model of thoracic radiation injury
James C Lee, Ryan Krochak, Aaron Blouin, Stathis Kanterakis, Shampa Chatterjee, Evguenia Arguiri, Anil Vachani, Charalambos C Solomides, Keith A Cengel & Melpo Christofidou-Solomidou
Pages: 47-53
Published online: 01 Jan 2009
AbstractforDietary flaxseed prevents radiation-induced oxidative lung damage, inflammation and fibrosis in a mouse model of thoracic radiation injury | PDF (1.7 MB)
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Article
PKCα activation down-regulates ATM and radio-sensitizes androgen-sensitive human prostate cancer cells in vitro and in vivo
Jean-Philip Truman, Susan A. Rotenberg, Ji-Hye Kang, Gabriel Lerman, Zvi Fuks, Richard Kolesnick, Victor E. Marquez & Adriana Haimovitz-Friedman
Pages: 54-63
Published online: 01 Jan 2009
AbstractforPKCα activation down-regulates ATM and radio-sensitizes androgen-sensitive human prostate cancer cells in vitro and in vivo | PDF (1.8 MB)
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Commentary

Ceramide-mediated apoptosis following ionizing radiation in human prostate cancer cells: PKCα joins the fray
Benjamin J Moeller, Renata Pasqualini & Wadih Arap
Pages: 64-65
Published online: 01 Jan 2009
AbstractforCeramide-mediated apoptosis following ionizing radiation in human prostate cancer cells: PKCα joins the fray | PDF (124.6 KB)
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Research Paper

Article
Depletion of CD4+CD25high regulatory T cells from tumor infiltrating lymphocytes predominantly induces Th1 type immune response in vivo which inhibits tumor growth in adoptive immunotherapy
Lin Xu, Wei Xu, Zhenggang Jiang, Feng Zhang, Yiwei Chu & Sidong Xiong
Pages: 66-72
Published online: 01 Jan 2009
AbstractforDepletion of CD4+CD25high regulatory T cells from tumor infiltrating lymphocytes predominantly induces Th1 type immune response in vivo which inhibits tumor growth in adoptive immunotherapy | PDF (1.1 MB)
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Article
Velcade sensitizes prostate cancer cells to TRAIL induced apoptosis and suppresses tumor growth in vivo
Perry A. Christian, Jeffery A. Thorpe & Steven R. Schwarze
Pages: 73-80
Published online: 01 Jan 2009
AbstractforVelcade sensitizes prostate cancer cells to TRAIL induced apoptosis and suppresses tumor growth in vivo | PDF (1.7 MB)
  • 278 Views
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Commentary

Combination therapy with TRAIL: Recent developments and potential pitfalls
Christina Voelkel-Johnson
Pages: 81-83
Published online: 01 Jan 2009
AbstractforCombination therapy with TRAIL: Recent developments and potential pitfalls | PDF (271.3 KB)
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Research Paper

Article
Inhibition of renal cancer cell growth by oncolytic adenovirus armed short hairpin RNA targeting hTERT gene
Jun-Nian Zheng, Dong-Sheng Pei, Fang-Hao Sun, Bao-Fu Zhang, Xin-Yuan Liu, Jin-Fa Gu, Yan-Hua Liu, Xue-Li Hu, Li-Jun Mao, Ru-Min Wen, Jun-Jie Liu & Wang Li
Pages: 84-91
Published online: 01 Jan 2009
AbstractforInhibition of renal cancer cell growth by oncolytic adenovirus armed short hairpin RNA targeting hTERT gene | PDF (1.5 MB)
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Commentary

Potentiation of oncolytic virotherapy with armed shRNA
Wei Guo & Bingliang Fang
Pages: 92-93
Published online: 01 Jan 2009
AbstractforPotentiation of oncolytic virotherapy with armed shRNA | PDF (500 KB)
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Research Paper

Article
Epigenetic downregulation of the DNA repair gene MED1/MBD4 in colorectal and ovarian cancer
J. Harrison Howard, Andrey Frolov, Ching-Wei D. Tzeng, Ashley Stewart, Andrew Midzak, Amar Majmundar, Andrew Godwin, Martin Heslin, Martin Heslin, Alfonso Bellacosa & J. Pablo Arnoletti
Pages: 94-100
Published online: 01 Jan 2009
AbstractforEpigenetic downregulation of the DNA repair gene MED1/MBD4 in colorectal and ovarian cancer | PDF (368.8 KB)
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