Cancer Biology & Therapy, Volume 8, Issue 9 (2009)

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Cancer Biology & Therapy, Volume 8, Issue 9 (2009)

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Editor's Corner

Editorial
Cover Caption
Page: i
Published online: 01 May 2009
AbstractforCover Caption
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News

News
Distinguished physician-scientist, Dr. Mikhail Blagosklonny, joins Roswell Park Cancer Institute
Pages: 753-752
Published online: 01 May 2009
AbstractforDistinguished physician-scientist, Dr. Mikhail Blagosklonny, joins Roswell Park Cancer Institute | PDF (366.7 KB)
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News
Dana-Farber opens advanced cancer imaging center
Pages: 753-752
Published online: 01 May 2009
AbstractforDana-Farber opens advanced cancer imaging center | PDF (366.7 KB)
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News
U-M Cancer Center names Gruber to head prevention program
Pages: 753-752
Published online: 01 May 2009
AbstractforU-M Cancer Center names Gruber to head prevention program | PDF (366.7 KB)
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News
New imaging analysis predicts brain tumor survival
Pages: 753-752
Published online: 01 May 2009
AbstractforNew imaging analysis predicts brain tumor survival | PDF (366.7 KB)
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News
Drug reduces prostate cancer diagnosis in men at increased risk
Pages: 753-752
Published online: 01 May 2009
AbstractforDrug reduces prostate cancer diagnosis in men at increased risk | PDF (366.7 KB)
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News
UNC Lineberger researchers identify compound that may stop deadly brain tumors
Pages: 753-752
Published online: 01 May 2009
AbstractforUNC Lineberger researchers identify compound that may stop deadly brain tumors | PDF (366.7 KB)
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News
Molecular imaging to detect and monitor cancer
Pages: 753-752
Published online: 01 May 2009
AbstractforMolecular imaging to detect and monitor cancer | PDF (366.7 KB)
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Review

Review Article
Mucositis and non-invasive markers of small intestinal function
Katie L. Tooley, GS Howarth & Ross N. Butler
Pages: 753-758
Published online: 01 May 2009
AbstractforMucositis and non-invasive markers of small intestinal function | PDF (300 KB)
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Research Paper

Article
Comparitive study of efficacy, tolerability of four field box technique vs. two field anterior posterior technique in locally advanced carcinoma cervix:A prospective analysis
Deepak Gupta, Pragya Shukla, Shyam Singh Bisht, Aditi Aggarwal, Ankur Dhawan, Mohan Chand Pant, Madan Lal Bhatt, Rajeev Gupta, Kirti Srivastava, Seema Gupta & Madhu Srivastava
Pages: 759-764
Published online: 01 May 2009
AbstractforComparitive study of efficacy, tolerability of four field box technique vs. two field anterior posterior technique in locally advanced carcinoma cervix:A prospective analysis | PDF (1.3 MB)
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Article
NFκB activity and transcriptional responses in human breast adenocarcinoma cells after single and fractionated irradiation
Rakhesh Madhusoodhanan, Mohan Natarajan Natarajan, Jamunarani Veeraraghavan, Terence S. Herman & Natarajan Aravindan
Pages: 765-773
Published online: 01 May 2009
AbstractforNFκB activity and transcriptional responses in human breast adenocarcinoma cells after single and fractionated irradiation | PDF (1.6 MB)
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Commentary

Conventional radiotherapy or hypofractionation? A study of molecular changes resulting from different radiation fractionation schemes.
Julie Hamilton, Geoff Higgins & Eric Bernhard
Pages: 774-776
Published online: 01 May 2009
AbstractforConventional radiotherapy or hypofractionation? A study of molecular changes resulting from different radiation fractionation schemes. | PDF (279.3 KB)
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Research Paper

Article
Mutagenesis induced by targeted alpha therapy using 213Bi-cDTPA-9.2.27 in lacZ transgenic mice
Barry J Allen, Trina So, Syed M. Abbas Rizvi, Emma Song, Harvey Fernandez & Louise Lutz-Mann
Pages: 777-781
Published online: 01 May 2009
AbstractforMutagenesis induced by targeted alpha therapy using 213Bi-cDTPA-9.2.27 in lacZ transgenic mice | PDF (525.6 KB)
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Article
Modulation of thymidilate synthase and p53 expression by HDAC inhibitor vorinostat resulted in synergistic antitumor effect in combination with 5FU or Raltitrexed
Elena Di Gennaro, Francesca Bruzzese, Stefano Pepe, Alessandra Leone, Paolo Delrio, Pochi Subbarayan, Antonio Avallone & Alfredo Budillon
Pages: 782-791
Published online: 01 May 2009
AbstractforModulation of thymidilate synthase and p53 expression by HDAC inhibitor vorinostat resulted in synergistic antitumor effect in combination with 5FU or Raltitrexed | PDF (1.4 MB)
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Article
Heat shock protein 70 silencing enhances apoptosis inducing factor-mediated cell death in hepatocellular carcinoma HepG2 cells
Qing Zhu, Yan-Ming Xu, Li-Feng Wang, Yong Zhang, Fang Wang, Jing Zhao, Lin-Tao Jia, Wang-Gang Zhang & An-Gang Yang
Pages: 792-798
Published online: 01 May 2009
AbstractforHeat shock protein 70 silencing enhances apoptosis inducing factor-mediated cell death in hepatocellular carcinoma HepG2 cells | PDF (1.2 MB)
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Commentary

HSP70 silencing combined with AIF: A novel therapeutic approach for cancer
Jun Yang & Ben-Yi Li
Pages: 799-800
Published online: 01 May 2009
AbstractforHSP70 silencing combined with AIF: A novel therapeutic approach for cancer | PDF (74.3 KB)
  • 178 Views
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Research Paper

Article
Activation of Protein Kinase C by Phorbol 12-Myristate 13-Acetate suppresses the growth of lung cancer cells through KLF6 induction
Eiji Tahara, Humam Kadara, Ludovic Lacroix, Dafna Lotan & Reuben Lotan
Pages: 801-807
Published online: 01 May 2009
AbstractforActivation of Protein Kinase C by Phorbol 12-Myristate 13-Acetate suppresses the growth of lung cancer cells through KLF6 induction | PDF (1.2 MB)
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Article
BCL-2 antagonists interact synergistically with bortezomib in DLBCL cells in association with JNK activation and induction of ER stress
Girija Dasmahapatra, Dmitry Lembersky, Mohamed Rahmani, Lora Kramer, Jonathan Friedberg, Richard I. Fisher, Paul Dent & Steven Grant
Pages: 808-819
Published online: 01 May 2009
AbstractforBCL-2 antagonists interact synergistically with bortezomib in DLBCL cells in association with JNK activation and induction of ER stress | PDF (1.8 MB)
  • 460 Views
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Commentary

Piling up the JNK: Drug synergy through ER stress
Lauren M. Hertan & Constantinos Koumenis
Pages: 820-822
Published online: 01 May 2009
AbstractforPiling up the JNK: Drug synergy through ER stress | PDF (259.6 KB)
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Research Paper

Article
Sensitization to γ-irradiation-induced cell cycle arrest and apoptosis by the histone deacetylase inhibitor trichostatin A in non-small cell lung cancer (NSCLC) cells
Feng Zhang, Tao Zhang, Zeng-hui Teng, Rong Zhang, Jian-Bo Wang & Qi-Bing Mei
Pages: 823-831
Published online: 01 May 2009
AbstractforSensitization to γ-irradiation-induced cell cycle arrest and apoptosis by the histone deacetylase inhibitor trichostatin A in non-small cell lung cancer (NSCLC) cells | PDF (1.6 MB)
  • 680 Views
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Commentary

HDAC inhibitors and ionizing radiation: Combinatorial strategy to combat lung cancer
Devanand Sarkar
Pages: 832-834
Published online: 01 May 2009
AbstractforHDAC inhibitors and ionizing radiation: Combinatorial strategy to combat lung cancer | PDF (159.1 KB)
  • 262 Views
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Research Paper

Article
T351 protein, a novel tumor associated antigen and potential target for immunotherapy
Junhai Lu, Ning Kang, Lianxian Cui, Denian Ba, Shujun Cheng & Wei He
Pages: 835-843
Published online: 01 May 2009
AbstractforT351 protein, a novel tumor associated antigen and potential target for immunotherapy | PDF (1.1 MB)
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Commentary

Identification of a tumor associated antigen that can induce tumor specific cytotoxicity
Alexis Dunkle & You-Wen He
Pages: 844-845
Published online: 01 May 2009
AbstractforIdentification of a tumor associated antigen that can induce tumor specific cytotoxicity | PDF (77.5 KB)
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Research Paper

Article
PIM1 Protein Kinase regulates PRAS40 phosphorylation and mTOR activity in FDCP1 cells
Fengxue Zhang, Zanna M. Beharry, Thurl E. Harris, Michael B. Lilly, Charles D. Smith, Sandeep Mahajan & Andrew S. Kraft
Pages: 846-853
Published online: 01 May 2009
AbstractforPIM1 Protein Kinase regulates PRAS40 phosphorylation and mTOR activity in FDCP1 cells | PDF (574.6 KB)
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Commentary

Activation of mTOR: A new mechanism "PIMed"
Kathleen Buckley, Warren Fiskus & Kapil N. Bhalla
Pages: 854-855
Published online: 01 May 2009
AbstractforActivation of mTOR: A new mechanism "PIMed" | PDF (69.7 KB)
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Research Paper

Article
Sunitinib and PF-562,271 (FAK/Pyk2 inhibitor) effectively block growth and recovery of human hepatocellular carcinoma in a rat xenograft model
Cedo M Bagi, James Christensen, Darrel P Cohen, Walter G Roberts, Dean Wilkie, Terri Swanson, Theresa Tuthill & Catharine J Andresen
Pages: 856-865
Published online: 01 May 2009
AbstractforSunitinib and PF-562,271 (FAK/Pyk2 inhibitor) effectively block growth and recovery of human hepatocellular carcinoma in a rat xenograft model | PDF (2.1 MB)
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