Journal of Biopharmaceutical Statistics, Volume 10, Issue 3 (2000)

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Journal of Biopharmaceutical Statistics, Volume 10, Issue 3 (2000)

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Original Articles

Article
STATISTICAL ANALYSIS OF THE LONG-TERM EFFECTS OF RECOMBINANT HUMAN DEOXYRIBONUCLEASE ON PULMONARY FUNCTION IN CYSTIC FIBROSIS PATIENTS
John J. Chen & Scott A. Hamilton
Pages: 287-297
Published online: 02 Feb 2007
AbstractforSTATISTICAL ANALYSIS OF THE LONG-TERM EFFECTS OF RECOMBINANT HUMAN DEOXYRIBONUCLEASE ON PULMONARY FUNCTION IN CYSTIC FIBROSIS PATIENTS | Full Text | References | PDF (130.5 KB)
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Article
ROBUSTNESS OF THE QUARTILES OF SURVIVAL TIME AND SURVIVAL PROBABILITY
Parichehr Hemyari
Pages: 299-318
Published online: 02 Feb 2007
AbstractforROBUSTNESS OF THE QUARTILES OF SURVIVAL TIME AND SURVIVAL PROBABILITY | Full Text | References | PDF (771.2 KB)
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Article
A TWO-STAGE DOSE SELECTION STRATEGY IN PHASE I TRIALS WITH WIDE DOSE RANGES
Ouhong Wang & Douglas E. Faries
Pages: 319-333
Published online: 02 Feb 2007
AbstractforA TWO-STAGE DOSE SELECTION STRATEGY IN PHASE I TRIALS WITH WIDE DOSE RANGES | Full Text | References | PDF (364.2 KB)
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Article
SIMULTANEOUS TESTING STRATEGY FOR COMPARING TWO TREATMENTS IN A STRATIFIED BINOMIAL TRIAL
R. A. Railkar, D. V. Mehrotra & B. Iglewicz
Pages: 335-349
Published online: 02 Feb 2007
AbstractforSIMULTANEOUS TESTING STRATEGY FOR COMPARING TWO TREATMENTS IN A STRATIFIED BINOMIAL TRIAL | Full Text | References | PDF (154.7 KB)
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Article
OPTIMAL DESIGNS FOR THE INDIVIDUAL AND JOINT EXPOSURE GENERAL LOGISTIC REGRESSION MODELS
Joseph M. Antonello & Damaraju Raghavarao
Pages: 351-367
Published online: 02 Feb 2007
AbstractforOPTIMAL DESIGNS FOR THE INDIVIDUAL AND JOINT EXPOSURE GENERAL LOGISTIC REGRESSION MODELS | Full Text | References | PDF (194.7 KB)
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Article
MODELING PHARMACOKINETIC DATA USING HEAVY-TAILED MULTIVARIATE DISTRIBUTIONS
J. K. Lindsey & B. Jones
Pages: 369-381
Published online: 02 Feb 2007
AbstractforMODELING PHARMACOKINETIC DATA USING HEAVY-TAILED MULTIVARIATE DISTRIBUTIONS | Full Text | References | PDF (142 KB)
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Article
LINEAR MIXED-EFFECT MULTIVARIATE ADAPTIVE REGRESSION SPLINES APPLIED TO NONLINEAR PHARMACOKINETICS DATA
Jean-Michel Gries & Davide Verotta
Pages: 383-398
Published online: 02 Feb 2007
AbstractforLINEAR MIXED-EFFECT MULTIVARIATE ADAPTIVE REGRESSION SPLINES APPLIED TO NONLINEAR PHARMACOKINETICS DATA | Full Text | References | PDF (182.5 KB)
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Article
ON THE TIMING OF A FUTILITY ANALYSIS IN CLINICAL TRIALS
Allan Pallay
Pages: 399-405
Published online: 02 Feb 2007
AbstractforON THE TIMING OF A FUTILITY ANALYSIS IN CLINICAL TRIALS | Full Text | References | PDF (100 KB)
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Article
ASSESSMENT OF SELECTION BIAS IN ESTIMATES OF RELATIVE BIOAVAILABILITY AND INTRASUBJECT VARIABILITY FROM BIOEQUIVALENCE EVALUATIONS
Yibin Wang
Pages: 407-424
Published online: 02 Feb 2007
AbstractforASSESSMENT OF SELECTION BIAS IN ESTIMATES OF RELATIVE BIOAVAILABILITY AND INTRASUBJECT VARIABILITY FROM BIOEQUIVALENCE EVALUATIONS | Full Text | References | PDF (222.4 KB)
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Article
ADJUSTING DISSOLUTION SPECIFICATIONS FOR THE VARIABILITY INDUCED BY STORAGE CONDITIONS
James M. Reynolds & David H. Rogers
Pages: 425-431
Published online: 02 Feb 2007
AbstractforADJUSTING DISSOLUTION SPECIFICATIONS FOR THE VARIABILITY INDUCED BY STORAGE CONDITIONS | Full Text | References | PDF (101.3 KB)
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Article
EQUIVALENCE IN TEST ASSAY METHOD COMPARISONS FOR THE REPEATED-MEASURE, MATCHED-PAIR DESIGN IN MEDICAL DEVICE STUDIES: STATISTICAL CONSIDERATIONS*
Chang S. Lao
Pages: 433-445
Published online: 02 Feb 2007
AbstractforEQUIVALENCE IN TEST ASSAY METHOD COMPARISONS FOR THE REPEATED-MEASURE, MATCHED-PAIR DESIGN IN MEDICAL DEVICE STUDIES: STATISTICAL CONSIDERATIONS* | Full Text | References | PDF (133.8 KB)
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