Molecular and Cellular Biology, Volume 20, Issue 6 (2000)

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Molecular and Cellular Biology, Volume 20, Issue 6 (2000)

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Article
ATP-Dependent Chromatin-Remodeling Complexes
Marissa Vignali, Ahmed H. Hassan, Kristen E. Neely & Jerry L. Workman
Pages: 1899-1910
Published online: 28 Mar 2023
First Page PreviewforATP-Dependent Chromatin-Remodeling Complexes | Full Text | References | PDF (758.2 KB)
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Transcriptional Regulation

Article
BSAP Can Repress Enhancer Activity by Targeting PU.1 Function
Shanak Maitra & Michael Atchison
Pages: 1911-1922
Published online: 28 Mar 2023
AbstractforBSAP Can Repress Enhancer Activity by Targeting PU.1 Function | Full Text | References | PDF (2.3 MB)
  • 21 Views
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Article
Acetyl Coenzyme A Stimulates RNA Polymerase II Transcription and Promoter Binding by Transcription Factor IID in the Absence of Histones
Shelly K. Galasinski, Tricia N. Lively, Alexandra Grebe de Barron & James A. Goodrich
Pages: 1923-1930
Published online: 28 Mar 2023
AbstractforAcetyl Coenzyme A Stimulates RNA Polymerase II Transcription and Promoter Binding by Transcription Factor IID in the Absence of Histones | Full Text | References | PDF (1.2 MB)
  • 15 Views
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Article
Loading of DNA-Binding Factors to an Erythroid Enhancer
Shau-Ching Wen, Karim Roder, Kuang-Yu Hu, Irene Rombel, Narender R. Gavva, Pratibha Daftari, Yun-Yeh Kuo, Chung Wang & C.-K. James Shen
Pages: 1993-2003
Published online: 28 Mar 2023
AbstractforLoading of DNA-Binding Factors to an Erythroid Enhancer | Full Text | References | PDF (852.5 KB)
  • 12 Views
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Article
Recruitment of the SWI-SNF Chromatin Remodeling Complex as a Mechanism of Gene Activation by the Glucocorticoid Receptor τ1 Activation Domain
Annika E. Wallberg, Kristen E. Neely, Ahmed H. Hassan, Jan-Åke Gustafsson, Jerry L. Workman & Anthony P. H. Wright
Pages: 2004-2013
Published online: 28 Mar 2023
AbstractforRecruitment of the SWI-SNF Chromatin Remodeling Complex as a Mechanism of Gene Activation by the Glucocorticoid Receptor τ1 Activation Domain | Full Text | References | PDF (1.9 MB)
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Article
The p53 Tumor Suppressor Protein Does Not Regulate Expression of Its Own Inhibitor, MDM2, Except under Conditions of Stress
Susan M. Mendrysa & Mary Ellen Perry
Pages: 2023-2030
Published online: 28 Mar 2023
AbstractforThe p53 Tumor Suppressor Protein Does Not Regulate Expression of Its Own Inhibitor, MDM2, Except under Conditions of Stress | Full Text | References | PDF (1.4 MB)
  • 13 Views
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Article
p300 Requires Its Histone Acetyltransferase Activity and SRC-1 Interaction Domain To Facilitate Thyroid Hormone Receptor Activation in Chromatin
Jiwen Li, Bert W. O'Malley & Jiemin Wong
Pages: 2031-2042
Published online: 28 Mar 2023
Abstractforp300 Requires Its Histone Acetyltransferase Activity and SRC-1 Interaction Domain To Facilitate Thyroid Hormone Receptor Activation in Chromatin | Full Text | References | PDF (5.3 MB)
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Article
The ETO Protein Disrupted in t(8;21)-Associated Acute Myeloid Leukemia Is a Corepressor for the Promyelocytic Leukemia Zinc Finger Protein
Ari M. Melnick, Jennifer J. Westendorf, Adam Polinger, Graeme W. Carlile, Sally Arai, Helen J. Ball, Bart Lutterbach, Scott W. Hiebert & Jonathan D. Licht
Pages: 2075-2086
Published online: 28 Mar 2023
AbstractforThe ETO Protein Disrupted in t(8;21)-Associated Acute Myeloid Leukemia Is a Corepressor for the Promyelocytic Leukemia Zinc Finger Protein | Full Text | References | PDF (1.1 MB)
  • 31 Views
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Article
Cloning of a Mammalian Transcriptional Activator That Binds Unmethylated CpG Motifs and Shares a CXXC Domain with DNA Methyltransferase, Human Trithorax, and Methyl-CpG Binding Domain Protein 1
Kui Shin Voo, Diana L. Carlone, Britta M. Jacobsen, Anna Flodin & David G. Skalnik
Pages: 2108-2121
Published online: 28 Mar 2023
AbstractforCloning of a Mammalian Transcriptional Activator That Binds Unmethylated CpG Motifs and Shares a CXXC Domain with DNA Methyltransferase, Human Trithorax, and Methyl-CpG Binding Domain Protein 1 | Full Text | References | PDF (5.1 MB)
  • 63 Views
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Article
E1A-Mediated Repression of Progesterone Receptor-Dependent Transactivation Involves Inhibition of the Assembly of a Multisubunit Coactivation Complex
Yue Xu, Ludger Klein-Hitpass & Milan K. Bagchi
Pages: 2138-2146
Published online: 28 Mar 2023
AbstractforE1A-Mediated Repression of Progesterone Receptor-Dependent Transactivation Involves Inhibition of the Assembly of a Multisubunit Coactivation Complex | Full Text | References | PDF (1.3 MB)
  • 5 Views
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Article
Transcriptional Repression by Neuron-Restrictive Silencer Factor Is Mediated via the Sin3-Histone Deacetylase Complex
Avtar Roopra, Lisa Sharling, Ian C. Wood, Teresa Briggs, Ulla Bachfischer, Alice J. Paquette & Noel J. Buckley
Pages: 2147-2157
Published online: 28 Mar 2023
AbstractforTranscriptional Repression by Neuron-Restrictive Silencer Factor Is Mediated via the Sin3-Histone Deacetylase Complex | Full Text | References | PDF (1.6 MB)
  • 61 Views
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Article
Stimulus-Specific Assembly of Enhancer Complexes on the Tumor Necrosis Factor Alpha Gene Promoter
James V. Falvo, Adele M. Uglialoro, Brigitta M. N. Brinkman, Menie Merika, Bhavin S. Parekh, Eunice Y. Tsai, Hadley C. King, Anthony D. Morielli, Ernest G. Peralta, Tom Maniatis, Dimitris Thanos & Anne E. Goldfeld
Pages: 2239-2247
Published online: 28 Mar 2023
AbstractforStimulus-Specific Assembly of Enhancer Complexes on the Tumor Necrosis Factor Alpha Gene Promoter | Full Text | References | PDF (1.2 MB)
  • 23 Views
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Cell Growth and Development

Article
Nerve Growth Factor Activation of the Extracellular Signal-Regulated Kinase Pathway Is Modulated by Ca2+and Calmodulin
Joaquim Egea, Carme Espinet, Rosa M. Soler, Sandra Peiró, Nativitat Rocamora & Joan X. Comella
Pages: 1931-1946
Published online: 28 Mar 2023
AbstractforNerve Growth Factor Activation of the Extracellular Signal-Regulated Kinase Pathway Is Modulated by Ca2+and Calmodulin | Full Text | References | PDF (2.8 MB)
  • 15 Views
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Article
Rap1 Is a Potent Activation Signal for Leukocyte Function-Associated Antigen 1 Distinct from Protein Kinase C and Phosphatidylinositol-3-OH Kinase
Koko Katagiri, Masakazu Hattori, Nagahiro Minato, Shin-kichi Irie, Kiyoshi Takatsu & Tatsuo Kinashi
Pages: 1956-1969
Published online: 28 Mar 2023
AbstractforRap1 Is a Potent Activation Signal for Leukocyte Function-Associated Antigen 1 Distinct from Protein Kinase C and Phosphatidylinositol-3-OH Kinase | Full Text | References | PDF (2.7 MB)
  • 37 Views
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Article
Regulation of the Resident Chromosomal Copy of c-myc by c-Myb Is Involved in Myeloid Leukemogenesis
M. Schmidt, V. Nazarov, L. Stevens, R. Watson & L. Wolff
Pages: 1970-1981
Published online: 28 Mar 2023
AbstractforRegulation of the Resident Chromosomal Copy of c-myc by c-Myb Is Involved in Myeloid Leukemogenesis | Full Text | References | PDF (1.6 MB)
  • 12 Views
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Article
Pocket Protein-Independent Repression of Urokinase-Type Plasminogen Activator and Plasminogen Activator Inhibitor 1 Gene Expression by E2F1
Magdalena Koziczak, Wilhelm Krek & Yoshikuni Nagamine
Pages: 2014-2022
Published online: 28 Mar 2023
AbstractforPocket Protein-Independent Repression of Urokinase-Type Plasminogen Activator and Plasminogen Activator Inhibitor 1 Gene Expression by E2F1 | Full Text | References | PDF (569.7 KB)
  • 9 Views
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Article
Etk, a Btk Family Tyrosine Kinase, Mediates Cellular Transformation by Linking Src to STAT3 Activation
Yuh-Tyng Tsai, Yi-Hsien Su, Shih-Shuan Fang, Tzye-Nan Huang, Yun Qiu, Yuh-Shan Jou, Hsiu-ming Shih, Hsing-Jien Kung & Ruey-Hwa Chen
Pages: 2043-2054
Published online: 28 Mar 2023
AbstractforEtk, a Btk Family Tyrosine Kinase, Mediates Cellular Transformation by Linking Src to STAT3 Activation | Full Text | References | PDF (2.5 MB)
  • 30 Views
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Article
Disassociation of Met-Mediated Biological Responses In Vivo: the Natural Hepatocyte Growth Factor/Scatter Factor Splice Variant NK2 Antagonizes Growth but Facilitates Metastasis
Toshiyuki Otsuka, John Jakubczak, Wilfred Vieira, Donald P. Bottaro, Diane Breckenridge, William J. Larochelle & Glenn Merlino
Pages: 2055-2065
Published online: 28 Mar 2023
AbstractforDisassociation of Met-Mediated Biological Responses In Vivo: the Natural Hepatocyte Growth Factor/Scatter Factor Splice Variant NK2 Antagonizes Growth but Facilitates Metastasis | Full Text | References | PDF (1.9 MB)
  • 6 Views
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Article
RRS1, a Conserved Essential Gene, Encodes a Novel Regulatory Protein Required for Ribosome Biogenesis in Saccharomyces cerevisiae
Akiko Tsuno, Keita Miyoshi, Rota Tsujii, Tokichi Miyakawa & Keiko Mizuta
Pages: 2066-2074
Published online: 28 Mar 2023
AbstractforRRS1, a Conserved Essential Gene, Encodes a Novel Regulatory Protein Required for Ribosome Biogenesis in Saccharomyces cerevisiae | Full Text | References | PDF (3.4 MB)
  • 31 Views
  • 60 CrossRef citations
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Article
The Interaction between the Drosophila Secreted Protein Argos and the Epidermal Growth Factor Receptor Inhibits Dimerization of the Receptor and Binding of Secreted Spitz to the Receptor
Ming-hao Jin, Kazunobu Sawamoto, Mikiko Ito & Hideyuki Okano
Pages: 2098-2107
Published online: 28 Mar 2023
AbstractforThe Interaction between the Drosophila Secreted Protein Argos and the Epidermal Growth Factor Receptor Inhibits Dimerization of the Receptor and Binding of Secreted Spitz to the Receptor | Full Text | References | PDF (1.4 MB)
  • 13 Views
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Article
The Branch Point Enzyme of the Mevalonate Pathway for Protein Prenylation Is Overexpressed in the ob/ob Mouse and Induced by Adipogenesis
David Vicent, Eleftheria Maratos-Flier & C. Ronald Kahn
Pages: 2158-2166
Published online: 28 Mar 2023
AbstractforThe Branch Point Enzyme of the Mevalonate Pathway for Protein Prenylation Is Overexpressed in the ob/ob Mouse and Induced by Adipogenesis | Full Text | References | PDF (1.6 MB)
  • 26 Views
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Article
Apoptotic and Growth-Promoting Activity of E2F Modulated by MDM2
Öonagh Loughran & Nicholas B. La Thangue
Pages: 2186-2197
Published online: 28 Mar 2023
AbstractforApoptotic and Growth-Promoting Activity of E2F Modulated by MDM2 | Full Text | References | PDF (1.9 MB)
  • 19 Views
  • 60 CrossRef citations
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Article
Activation of Apoptosis Signal-Regulating Kinase 1 (ASK1) by Tumor Necrosis Factor Receptor-Associated Factor 2 Requires Prior Dissociation of the ASK1 Inhibitor Thioredoxin
Hong Liu, Hideki Nishitoh, Hidenori Ichijo & John M. Kyriakis
Pages: 2198-2208
Published online: 28 Mar 2023
AbstractforActivation of Apoptosis Signal-Regulating Kinase 1 (ASK1) by Tumor Necrosis Factor Receptor-Associated Factor 2 Requires Prior Dissociation of the ASK1 Inhibitor Thioredoxin | Full Text | References | PDF (1.5 MB)
  • 46 Views
  • 414 CrossRef citations
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Article
Two Independent Signaling Pathways Mediate the Antiapoptotic Action of Macrophage-Stimulating Protein on Epithelial Cells
Alla Danilkovitch, Shannon Donley, Alison Skeel & Edward J. Leonard
Pages: 2218-2227
Published online: 28 Mar 2023
AbstractforTwo Independent Signaling Pathways Mediate the Antiapoptotic Action of Macrophage-Stimulating Protein on Epithelial Cells | Full Text | References | PDF (1.9 MB)
  • 10 Views
  • 80 CrossRef citations
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Article
Interaction of Dishevelled and Xenopus Axin-Related Protein Is Required for Wnt Signal Transduction
Keiji Itoh, Alena Antipova, Marianne J. Ratcliffe & Sergei Sokol
Pages: 2228-2238
Published online: 28 Mar 2023
AbstractforInteraction of Dishevelled and Xenopus Axin-Related Protein Is Required for Wnt Signal Transduction | Full Text | References | PDF (2.2 MB)
  • 4 Views
  • 75 CrossRef citations
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Article
mSin3A Regulates Murine Erythroleukemia Cell Differentiation through Association with the TAL1 (or SCL) Transcription Factor
Suming Huang & Stephen J. Brandt
Pages: 2248-2259
Published online: 28 Mar 2023
AbstractformSin3A Regulates Murine Erythroleukemia Cell Differentiation through Association with the TAL1 (or SCL) Transcription Factor | Full Text | References | PDF (1.3 MB)
  • 20 Views
  • 85 CrossRef citations
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Article
Structure and Function Analysis of LIN-14, a Temporal Regulator of Postembryonic Developmental Events in Caenorhabditis elegans
Yang Hong, Rosalind C. Lee & Victor Ambros
Pages: 2285-2295
Published online: 28 Mar 2023
AbstractforStructure and Function Analysis of LIN-14, a Temporal Regulator of Postembryonic Developmental Events in Caenorhabditis elegans | Full Text | References | PDF (2.8 MB)
  • 43 Views
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Dna Dynamics and Chromosome Structure

Article
The Est1 Subunit of Yeast Telomerase Binds the Tlc1 Telomerase RNA
Jianlong Zhou, Kyoko Hidaka & Bruce Futcher
Pages: 1947-1955
Published online: 28 Mar 2023
AbstractforThe Est1 Subunit of Yeast Telomerase Binds the Tlc1 Telomerase RNA | Full Text | References | PDF (2.8 MB)
  • 34 Views
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Article
The H3-H4 N-Terminal Tail Domains Are the Primary Mediators of Transcription Factor IIIA Access to 5S DNA within a Nucleosome
Joseph M. Vitolo, Christophe Thiriet & Jeffrey J. Hayes
Pages: 2167-2175
Published online: 28 Mar 2023
AbstractforThe H3-H4 N-Terminal Tail Domains Are the Primary Mediators of Transcription Factor IIIA Access to 5S DNA within a Nucleosome | Full Text | References | PDF (2.2 MB)
  • 14 Views
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Gene Expression

Article
An AU-Rich Sequence Element (UUUN[A/U]U) Downstream of the Edited C in Apolipoprotein B mRNA Is a High-Affinity Binding Site for Apobec-1: Binding of Apobec-1 to This Motif in the 3′ Untranslated Region of c-myc Increases mRNA Stability
Shrikant Anant & Nicholas O. Davidson
Pages: 1982-1992
Published online: 28 Mar 2023
AbstractforAn AU-Rich Sequence Element (UUUN[A/U]U) Downstream of the Edited C in Apolipoprotein B mRNA Is a High-Affinity Binding Site for Apobec-1: Binding of Apobec-1 to This Motif in the 3′ Untranslated Region of c-myc Increases mRNA Stability | Full Text | References | PDF (2.6 MB)
  • 13 Views
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Article
ArgRII, a Component of the ArgR-Mcm1 Complex Involved in the Control of Arginine Metabolism in Saccharomyces cerevisiae, Is the Sensor of Arginine
Najet Amar, Francine Messenguy, Mohamed El Bakkoury & Evelyne Dubois
Pages: 2087-2097
Published online: 28 Mar 2023
AbstractforArgRII, a Component of the ArgR-Mcm1 Complex Involved in the Control of Arginine Metabolism in Saccharomyces cerevisiae, Is the Sensor of Arginine | Full Text | References | PDF (990.4 KB)
  • 9 Views
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Article
Rapid Deadenylation and Poly(A)-Dependent Translational Repression Mediated by the Caenorhabditis elegans tra-2 3′ Untranslated Region in Xenopus Embryos
Sunnie R. Thompson, Elizabeth B. Goodwin & Marvin Wickens
Pages: 2129-2137
Published online: 28 Mar 2023
AbstractforRapid Deadenylation and Poly(A)-Dependent Translational Repression Mediated by the Caenorhabditis elegans tra-2 3′ Untranslated Region in Xenopus Embryos | Full Text | References | PDF (781.8 KB)
  • 13 Views
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Article
Functional Cus1p Is Found with Hsh155p in a Multiprotein Splicing Factor Associated with U2 snRNA
Michelle Haynes Pauling, David S. McPheeters & Manuel Ares Jr.
Pages: 2176-2185
Published online: 28 Mar 2023
AbstractforFunctional Cus1p Is Found with Hsh155p in a Multiprotein Splicing Factor Associated with U2 snRNA | Full Text | References | PDF (2.6 MB)
  • 6 Views
  • 23 CrossRef citations
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Article
Fourteen Residues of the U1 snRNP-Specific U1A Protein Are Required for Homodimerization, Cooperative RNA Binding, and Inhibition of Polyadenylation
Jacqueline M. T. Klein Gunnewiek, Reem I. Hussein, Yvonne van Aarssen, Daphne Palacios, Rob de Jong, Walther J. van Venrooij & Samuel I. Gunderson
Pages: 2209-2217
Published online: 28 Mar 2023
AbstractforFourteen Residues of the U1 snRNP-Specific U1A Protein Are Required for Homodimerization, Cooperative RNA Binding, and Inhibition of Polyadenylation | Full Text | References | PDF (1,004.2 KB)
  • 30 Views
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Mammalian Genetic Models With Minimal Or Complex Phenotypes

Article
Normal Spermatogenesis in Mice Lacking the Testis-Specific Linker Histone H1t
Qingcong Lin, Allen Sirotkin & Arthur I. Skoultchi
Pages: 2122-2128
Published online: 28 Mar 2023
AbstractforNormal Spermatogenesis in Mice Lacking the Testis-Specific Linker Histone H1t | Full Text | References | PDF (284.9 KB)
  • 6 Views
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Article
Compensation by Fibroblast Growth Factor 1 (FGF1) Does Not Account for the Mild Phenotypic Defects Observed in FGF2 Null Mice
David L. Miller, Sagrario Ortega, Omar Bashayan, Ross Basch & Claudio Basilico
Pages: 2260-2268
Published online: 28 Mar 2023
AbstractforCompensation by Fibroblast Growth Factor 1 (FGF1) Does Not Account for the Mild Phenotypic Defects Observed in FGF2 Null Mice | Full Text | References | PDF (1,011.3 KB)
  • 106 Views
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Nucleocytoplasmic Communication

Article
Cytoplasmic Sequestration of Rel Proteins by IκBα Requires CRM1-Dependent Nuclear Export
Winnie F. Tam, Linda H. Lee, Laura Davis & Ranjan Sen
Pages: 2269-2284
Published online: 28 Mar 2023
AbstractforCytoplasmic Sequestration of Rel Proteins by IκBα Requires CRM1-Dependent Nuclear Export | Full Text | References | PDF (7.6 MB)
  • 10 Views
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