Molecular and Cellular Biology, Volume 22, Issue 16 (2002)

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Molecular and Cellular Biology, Volume 22, Issue 16 (2002)

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Gene Expression

Article
Luman, the Cellular Counterpart of Herpes Simplex Virus VP16, Is Processed by Regulated Intramembrane Proteolysis
Camilo Raggo, Noreen Rapin, Julie Stirling, Philipe Gobeil, Erin Smith-Windsor, Peter O'Hare & Vikram Misra
Pages: 5639-5649
Published online: 01 Apr 2023
AbstractforLuman, the Cellular Counterpart of Herpes Simplex Virus VP16, Is Processed by Regulated Intramembrane Proteolysis | Full Text | References | PDF (453.3 KB)
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Article
Regulation of Alternative Splicing by the ATP-Dependent DEAD-Box RNA Helicase p72
Arnd Hönig, Didier Auboeuf, Marjorie M. Parker, Bert W. O'Malley & Susan M. Berget
Pages: 5698-5707
Published online: 01 Apr 2023
AbstractforRegulation of Alternative Splicing by the ATP-Dependent DEAD-Box RNA Helicase p72 | Full Text | References | PDF (358.3 KB)
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Article
A Functional Screen for Myc-Responsive Genes Reveals Serine Hydroxymethyltransferase, a Major Source of the One-Carbon Unit for Cell Metabolism
Mikhail A. Nikiforov, Sanjay Chandriani, Brenda O'Connell, Oleksi Petrenko, Iulia Kotenko, Andrew Beavis, John M. Sedivy & Michael D. Cole
Pages: 5793-5800
Published online: 01 Apr 2023
AbstractforA Functional Screen for Myc-Responsive Genes Reveals Serine Hydroxymethyltransferase, a Major Source of the One-Carbon Unit for Cell Metabolism | Full Text | References | PDF (282 KB)
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Transcriptional Regulation

Article
Transcriptional Regulation of the mdm2 Oncogene by p53 Requires TRRAP Acetyltransferase Complexes
Penny G. Ard, Chandrima Chatterjee, Sudeesha Kunjibettu, Leon R. Adside, Lisa E. Gralinski & Steven B. McMahon
Pages: 5650-5661
Published online: 01 Apr 2023
AbstractforTranscriptional Regulation of the mdm2 Oncogene by p53 Requires TRRAP Acetyltransferase Complexes | Full Text | References | PDF (463.5 KB)
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Article
Involvement of Histone Methylation and Phosphorylation in Regulation of Transcription by Thyroid Hormone Receptor
Jiwen Li, Qiushi Lin, Ho-Geun Yoon, Zhi-Qing Huang, Brian D. Strahl, C. David Allis & Jiemin Wong
Pages: 5688-5697
Published online: 01 Apr 2023
AbstractforInvolvement of Histone Methylation and Phosphorylation in Regulation of Transcription by Thyroid Hormone Receptor | Full Text | References | PDF (258.3 KB)
  • 21 Views
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Article
Multiple Regulatory Domains of IRF-5 Control Activation, Cellular Localization, and Induction of Chemokines That Mediate Recruitment of T Lymphocytes
Betsy J. Barnes, Merrill J. Kellum, Ann E. Field & Paula M. Pitha
Pages: 5721-5740
Published online: 01 Apr 2023
AbstractforMultiple Regulatory Domains of IRF-5 Control Activation, Cellular Localization, and Induction of Chemokines That Mediate Recruitment of T Lymphocytes | Full Text | References | PDF (602.8 KB)
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Article
Swapping Functional Specificity of a MADS Box Protein: Residues Required for Arg80 Regulation of Arginine Metabolism
Adil Jamai, Evelyne Dubois, Andrew K. Vershon & Francine Messenguy
Pages: 5741-5752
Published online: 01 Apr 2023
AbstractforSwapping Functional Specificity of a MADS Box Protein: Residues Required for Arg80 Regulation of Arginine Metabolism | Full Text | References | PDF (651.5 KB)
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Article
TonEBP/NFAT5 Stimulates Transcription of HSP70 in Response to Hypertonicity
Seung Kyoon Woo, Sang Do Lee, Ki Young Na, Won Kun Park & H. Moo Kwon
Pages: 5753-5760
Published online: 01 Apr 2023
AbstractforTonEBP/NFAT5 Stimulates Transcription of HSP70 in Response to Hypertonicity | Full Text | References | PDF (277 KB)
  • 44 Views
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Article
Functional Evidence for Retinoid X Receptor (RXR) as a Nonsilent Partner in the Thyroid Hormone Receptor/RXR Heterodimer
Dangsheng Li, Tong Li, Fang Wang, Heather Tian & Herbert H. Samuels
Pages: 5782-5792
Published online: 01 Apr 2023
AbstractforFunctional Evidence for Retinoid X Receptor (RXR) as a Nonsilent Partner in the Thyroid Hormone Receptor/RXR Heterodimer | Full Text | References | PDF (153.5 KB)
  • 42 Views
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Article
Regulation of Estrogen Receptor Nuclear Export by Ligand-Induced and p38-Mediated Receptor Phosphorylation
Heehyoung Lee & Wenlong Bai
Pages: 5835-5845
Published online: 01 Apr 2023
AbstractforRegulation of Estrogen Receptor Nuclear Export by Ligand-Induced and p38-Mediated Receptor Phosphorylation | Full Text | References | PDF (416.9 KB)
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Article
The Function of TIF2/GRIP1 in Mouse Reproduction Is Distinct from Those of SRC-1 and p/CIP
Martine Gehin, Manuel Mark, Christine Dennefeld, Andrée Dierich, Hinrich Gronemeyer & Pierre Chambon
Pages: 5923-5937
Published online: 01 Apr 2023
AbstractforThe Function of TIF2/GRIP1 in Mouse Reproduction Is Distinct from Those of SRC-1 and p/CIP | Full Text | References | PDF (2.3 MB)
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Article
Cell Cycle Arrest and Repression of Cyclin D1 Transcription by INI1/hSNF5
Zhi-Kai Zhang, Kelvin P. Davies, Jeffrey Allen, Liang Zhu, Richard G. Pestell, David Zagzag & Ganjam V. Kalpana
Pages: 5975-5988
Published online: 01 Apr 2023
AbstractforCell Cycle Arrest and Repression of Cyclin D1 Transcription by INI1/hSNF5 | Full Text | References | PDF (678 KB)
  • 20 Views
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Article
Microarray Analyses during Adipogenesis: Understanding the Effects of Wnt Signaling on Adipogenesis and the Roles of Liver X Receptor α in Adipocyte Metabolism
Sarah E. Ross, Robin L. Erickson, Isabelle Gerin, Paul M. DeRose, Laszlo Bajnok, Kenneth A. Longo, David E. Misek, Rork Kuick, Samir M. Hanash, Kevin B. Atkins, Sissel M. Andresen, Hilde I. Nebb, Lise Madsen, Karsten Kristiansen & Ormond A. MacDougald
Pages: 5989-5999
Published online: 01 Apr 2023
AbstractforMicroarray Analyses during Adipogenesis: Understanding the Effects of Wnt Signaling on Adipogenesis and the Roles of Liver X Receptor α in Adipocyte Metabolism | Full Text | References | PDF (705.5 KB)
  • 68 Views
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Article
Molecular Characterization of Saccharomyces cerevisiae TFIID
Steven L. Sanders, Krassimira A. Garbett & P. Anthony Weil
Pages: 6000-6013
Published online: 01 Apr 2023
AbstractforMolecular Characterization of Saccharomyces cerevisiae TFIID | Full Text | References | PDF (626.5 KB)
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Cell Growth and Development

Article
Identification of a Nuclear Stat1 Protein Tyrosine Phosphatase
Johanna ten Hoeve, Maria de Jesus Ibarra-Sanchez, Yubin Fu, Wei Zhu, Michel Tremblay, Michael David & Ke Shuai
Pages: 5662-5668
Published online: 01 Apr 2023
AbstractforIdentification of a Nuclear Stat1 Protein Tyrosine Phosphatase | Full Text | References | PDF (333.9 KB)
  • 177 Views
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Article
Disruption of Mekk2 in Mice Reveals an Unexpected Role for MEKK2 in Modulating T-Cell Receptor Signal Transduction
Zijian Guo, Gavin Clydesdale, Jinke Cheng, Kihwan Kim, Lin Gan, David J. McConkey, Stephen E. Ullrich, Yuan Zhuang & Bing Su
Pages: 5761-5768
Published online: 01 Apr 2023
AbstractforDisruption of Mekk2 in Mice Reveals an Unexpected Role for MEKK2 in Modulating T-Cell Receptor Signal Transduction | Full Text | References | PDF (303.1 KB)
  • 19 Views
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Article
Human Papillomavirus Oncoprotein E6 Inactivates the Transcriptional Coactivator Human ADA3
Ajay Kumar, Yongtong Zhao, Gaoyuan Meng, Musheng Zeng, Seetha Srinivasan, Laurie M. Delmolino, Qingshen Gao, Goberdhan Dimri, Georg F. Weber, David E. Wazer, Hamid Band & Vimla Band
Pages: 5801-5812
Published online: 01 Apr 2023
AbstractforHuman Papillomavirus Oncoprotein E6 Inactivates the Transcriptional Coactivator Human ADA3 | Full Text | References | PDF (473 KB)
  • 14 Views
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Article
The Zinc Finger Domain of NEMO Is Selectively Required for NF-κB Activation by UV Radiation and Topoisomerase Inhibitors
Tony T. Huang, Shelby L. Feinberg, Sainath Suryanarayanan & Shigeki Miyamoto
Pages: 5813-5825
Published online: 01 Apr 2023
AbstractforThe Zinc Finger Domain of NEMO Is Selectively Required for NF-κB Activation by UV Radiation and Topoisomerase Inhibitors | Full Text | References | PDF (552.5 KB)
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Article
Suprabasal Desmoglein 3 Expression in the Epidermis of Transgenic Mice Results in Hyperproliferation and Abnormal Differentiation
Anita J. Merritt, Mohamed Y. Berika, Wenwu Zhai, Sarah E. Kirk, Baijing Ji, Matthew J. Hardman & David R. Garrod
Pages: 5846-5858
Published online: 01 Apr 2023
AbstractforSuprabasal Desmoglein 3 Expression in the Epidermis of Transgenic Mice Results in Hyperproliferation and Abnormal Differentiation | Full Text | References | PDF (2.2 MB)
  • 39 Views
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Article
Different Roles for Nonhomologous End Joining and Homologous Recombination following Replication Arrest in Mammalian Cells
Cecilia Lundin, Klaus Erixon, Catherine Arnaudeau, Niklas Schultz, Dag Jenssen, Mark Meuth & Thomas Helleday
Pages: 5869-5878
Published online: 01 Apr 2023
AbstractforDifferent Roles for Nonhomologous End Joining and Homologous Recombination following Replication Arrest in Mammalian Cells | Full Text | References | PDF (584.9 KB)
  • 42 Views
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Article
RIP2, a Checkpoint in Myogenic Differentiation
Barbara Munz, Eberhard Hildt, Matthew L. Springer & Helen M. Blau
Pages: 5879-5886
Published online: 01 Apr 2023
AbstractforRIP2, a Checkpoint in Myogenic Differentiation | Full Text | References | PDF (336.2 KB)
  • 11 Views
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Article
Site-Directed Perturbation of Protein Kinase C- Integrin Interaction Blocks Carcinoma Cell Chemotaxis
Maddy Parsons, Melanie D. Keppler, Adam Kline, Anthea Messent, Martin J. Humphries, Ruth Gilchrist, Ian R. Hart, Corinne Quittau-Prevostel, William E. Hughes, Peter J. Parker & Tony Ng
Pages: 5897-5911
Published online: 01 Apr 2023
AbstractforSite-Directed Perturbation of Protein Kinase C- Integrin Interaction Blocks Carcinoma Cell Chemotaxis | Full Text | References | PDF (1.2 MB)
  • 13 Views
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Article
α5β1 Integrin Activates an NF-κB-Dependent Program of Gene Expression Important for Angiogenesis and Inflammation
Sharon Klein, Antonin R. de Fougerolles, Pamela Blaikie, Leila Khan, Angela Pepe, Cynthia D. Green, Victor Koteliansky & Filippo G. Giancotti
Pages: 5912-5922
Published online: 01 Apr 2023
Abstractforα5β1 Integrin Activates an NF-κB-Dependent Program of Gene Expression Important for Angiogenesis and Inflammation | Full Text | References | PDF (963.3 KB)
  • 59 Views
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Article
R-Ras3/M-Ras Induces Neuronal Differentiation of PC12 Cells through Cell-Type-Specific Activation of the Mitogen-Activated Protein Kinase Cascade
Alec C. Kimmelman, Nelson Nuñez Rodriguez & Andrew M.-L. Chan
Pages: 5946-5961
Published online: 01 Apr 2023
AbstractforR-Ras3/M-Ras Induces Neuronal Differentiation of PC12 Cells through Cell-Type-Specific Activation of the Mitogen-Activated Protein Kinase Cascade | Full Text | References | PDF (967.5 KB)
  • 15 Views
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Article
Akt-Dependent Phosphorylation Specifically Regulates Cot Induction of NF-κB-Dependent Transcription
Lawrence P. Kane, Marianne N. Mollenauer, Zheng Xu, Christoph W. Turck & Arthur Weiss
Pages: 5962-5974
Published online: 01 Apr 2023
AbstractforAkt-Dependent Phosphorylation Specifically Regulates Cot Induction of NF-κB-Dependent Transcription | Full Text | References | PDF (816.7 KB)
  • 30 Views
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Article
Stress-Dependent Nucleolin Mobilization Mediated by p53-Nucleolin Complex Formation
Yaron Daniely, Diana D. Dimitrova & James A. Borowiec
Pages: 6014-6022
Published online: 01 Apr 2023
AbstractforStress-Dependent Nucleolin Mobilization Mediated by p53-Nucleolin Complex Formation | Full Text | References | PDF (533.3 KB)
  • 63 Views
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Dna Dynamics and Chromosome Structure

Article
Role of the p68 Subunit of Human DNA Polymerase α-Primase in Simian Virus 40 DNA Replication
Robert D. Ott, Christoph Rehfuess, Vladimir N. Podust, Jill E. Clark & Ellen Fanning
Pages: 5669-5678
Published online: 01 Apr 2023
AbstractforRole of the p68 Subunit of Human DNA Polymerase α-Primase in Simian Virus 40 DNA Replication | Full Text | References | PDF (408.6 KB)
  • 10 Views
  • 22 CrossRef citations
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Article
Involvement of Replicative Polymerases, Tel1p, Mec1p, Cdc13p, and the Ku Complex in Telomere-Telomere Recombination
Yun-Luen Tsai, Shun-Fu Tseng, Shih-Husan Chang, Chuan-Chuan Lin & Shu-Chun Teng
Pages: 5679-5687
Published online: 01 Apr 2023
AbstractforInvolvement of Replicative Polymerases, Tel1p, Mec1p, Cdc13p, and the Ku Complex in Telomere-Telomere Recombination | Full Text | References | PDF (294.5 KB)
  • 20 Views
  • 40 CrossRef citations
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Article
Identification of a Chromosome-Targeting Domain in the Human Condensin Subunit CNAP1/hCAP-D2/Eg7
Alexander R. Ball Jr., John A. Schmiesing, Changcheng Zhou, Heather C. Gregson, Yoshiaki Okada, Takefumi Doi & Kyoko Yokomori
Pages: 5769-5781
Published online: 01 Apr 2023
AbstractforIdentification of a Chromosome-Targeting Domain in the Human Condensin Subunit CNAP1/hCAP-D2/Eg7 | Full Text | References | PDF (708 KB)
  • 22 Views
  • 39 CrossRef citations
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Article
Interactions between Telomerase and Primase Physically Link the Telomere and Chromosome Replication Machinery
Saugata Ray, Zemfira Karamysheva, Libin Wang, Dorothy E. Shippen & Carolyn M. Price
Pages: 5859-5868
Published online: 01 Apr 2023
AbstractforInteractions between Telomerase and Primase Physically Link the Telomere and Chromosome Replication Machinery | Full Text | References | PDF (485.3 KB)
  • 5 Views
  • 37 CrossRef citations
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Article
Molecular Anatomy of the Human Excision Nuclease Assembled at Sites of DNA Damage
Joyce T. Reardon & Aziz Sancar
Pages: 5938-5945
Published online: 01 Apr 2023
AbstractforMolecular Anatomy of the Human Excision Nuclease Assembled at Sites of DNA Damage | Full Text | References | PDF (308.3 KB)
  • 16 Views
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Nucleocytoplasmic Communication

Article
Steady-State Nuclear Localization of Exportin-t Involves RanGTP Binding and Two Distinct Nuclear Pore Complex Interaction Domains
Scott Kuersten, Gert-Jan Arts, Tobias C. Walther, Ludwig Englmeier & Iain W. Mattaj
Pages: 5708-5720
Published online: 01 Apr 2023
AbstractforSteady-State Nuclear Localization of Exportin-t Involves RanGTP Binding and Two Distinct Nuclear Pore Complex Interaction Domains | Full Text | References | PDF (596.6 KB)
  • 20 Views
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Article
Sox10 Is an Active Nucleocytoplasmic Shuttle Protein, and Shuttling Is Crucial for Sox10-Mediated Transactivation
Stephan Rehberg, Peter Lischka, Gabi Glaser, Thomas Stamminger, Michael Wegner & Olaf Rosorius
Pages: 5826-5834
Published online: 01 Apr 2023
AbstractforSox10 Is an Active Nucleocytoplasmic Shuttle Protein, and Shuttling Is Crucial for Sox10-Mediated Transactivation | Full Text | References | PDF (533.2 KB)
  • 42 Views
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Mammalian Genetic Models With Minimal Or Complex Phenotypes

Article
Mice Lacking Skeletal Muscle Actin Show Reduced Muscle Strength and Growth Deficits and Die during the Neonatal Period
K. Crawford, R. Flick, L. Close, D. Shelly, R. Paul, K. Bove, A. Kumar & J. Lessard
Pages: 5887-5896
Published online: 01 Apr 2023
AbstractforMice Lacking Skeletal Muscle Actin Show Reduced Muscle Strength and Growth Deficits and Die during the Neonatal Period | Full Text | References | PDF (1.2 MB)
  • 37 Views
  • 82 CrossRef citations
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