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Volume 1, Issue 4

Statistics in Biopharmaceutical Research

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Statistics in Biopharmaceutical Research, Volume 1, Issue 4 (2009)

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Statistics in Biopharmaceutical Research, Volume 1, Issue 4 (2009)

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ICSA Special Issue

Preface to ICSA Special Issue

Joshua Chen & Minge Xie

Pages: 343-344

Published online: 01 Jan 2012

CitationforPreface to ICSA Special Issue | PDF (49.8 KB)

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Challenges and Opportunities for Statisticians in the 21st Century

Li-an Xu & Gang Li

Pages: 345-347

Published online: 01 Jan 2012

AbstractforChallenges and Opportunities for Statisticians in the 21st Century | PDF (62.3 KB)

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Articles

Article

Predicted Interval Plots (PIPS): A Graphical Tool for Data Monitoring of Clinical Trials

Lingling Li, Scott R. Evans, Hajime Uno & L.J. Wei

Pages: 348-355

Published online: 01 Jan 2012

AbstractforPredicted Interval Plots (PIPS): A Graphical Tool for Data Monitoring of Clinical Trials | PDF (496.8 KB)

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Article

A Short Note on Sample Size Estimation

K.K. Gordon Lan & Zhenming Shun

Pages: 356-361

Published online: 01 Jan 2012

AbstractforA Short Note on Sample Size Estimation | PDF (103.4 KB)

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Article

Uncertainty in Clinical Endpoints: Information and Retrieval

Hongwei Wang, Cong Chen & Steven M. Snapinn

Pages: 362-365

Published online: 01 Jan 2012

AbstractforUncertainty in Clinical Endpoints: Information and Retrieval | PDF (89.5 KB)

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Article

Adaptive Designs for Interim Dose Selection

Gang Li, Junhong Zhu, S. Peter Ouyang, John Xie, Ling Deng & Gordon Law

Pages: 366-376

Published online: 01 Jan 2012

AbstractforAdaptive Designs for Interim Dose Selection | PDF (119.4 KB)

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Article

Optimal Two-Stage Designs to Evaluate a Series of New Agents or Treatments

Vandana Mukhi & Yongzhao Shao

Pages: 377-387

Published online: 01 Jan 2012

AbstractforOptimal Two-Stage Designs to Evaluate a Series of New Agents or Treatments | PDF (148.9 KB)

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Article

A Unified Approach to Flexible Sample Size Design with Realistic Constraints

Zhenming Shun, Yi He, Yijia Feng & Martin Roessner

Pages: 388-398

Published online: 01 Jan 2012

AbstractforA Unified Approach to Flexible Sample Size Design with Realistic Constraints | PDF (221.9 KB)

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Article

Nonregular Robust Parameter Designs

Yingfu Li, Jiantian Wang & M. L. Aggarwal

Pages: 399-406

Published online: 01 Jan 2012

AbstractforNonregular Robust Parameter Designs | PDF (118.9 KB)

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Article

Empirical Likelihood-Based Confidence Interval of ROC Curves

Haiyan Su, Yongsong Qin & Hua Liang

Pages: 407-414

Published online: 01 Jan 2012

AbstractforEmpirical Likelihood-Based Confidence Interval of ROC Curves | PDF (137.5 KB)

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Article

Joint Modeling of Survival Data and Longitudinal Measurements Under Nested Case-Control Sampling

Chi-hong Tseng & Mengling Liu

Pages: 415-423

Published online: 01 Jan 2012

AbstractforJoint Modeling of Survival Data and Longitudinal Measurements Under Nested Case-Control Sampling | PDF (137.3 KB)

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Article

Detecting Genes and Gene–Gene Interactions for Age-Related Macular Degeneration with a Forest-based Approach

Minghui Wang, Meizhuo Zhang, Xiang Chen & Heping Zhang

Pages: 424-430

Published online: 01 Jan 2012

AbstractforDetecting Genes and Gene–Gene Interactions for Age-Related Macular Degeneration with a Forest-based Approach | PDF (180.4 KB)

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Article

Hypothesis Testing in a Confirmatory Phase III Trial With a Possible Subset Effect

Cong Chen & Robert A. Beckman

Pages: 431-440

Published online: 01 Jan 2012

AbstractforHypothesis Testing in a Confirmatory Phase III Trial With a Possible Subset Effect | PDF (145.3 KB)

164 Views
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Article

A Bayesian Design Space Approach to Robustness and System Suitability for Pharmaceutical Assays and Other Processes

John J. Peterson & Mohammad Yahyah

Pages: 441-449

Published online: 01 Jan 2012

AbstractforA Bayesian Design Space Approach to Robustness and System Suitability for Pharmaceutical Assays and Other Processes | PDF (1 MB)

150 Views
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Article

Transfer of Methods Supporting Biologics and Vaccines

Rong Liu, Timothy L. Schofield & Jason J.Z. Liao

Pages: 450-456

Published online: 01 Jan 2012

AbstractforTransfer of Methods Supporting Biologics and Vaccines | PDF (183.9 KB)

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Commentaries

Article Commentary

Commentary on “Personalized Medicine in Oncology: Hype or Hope?”

Sue-Jane Wang

Pages: 457-461

Published online: 01 Jan 2012

AbstractforCommentary on “Personalized Medicine in Oncology: Hype or Hope?” | PDF (100.8 KB)

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Article Commentary

Commentary on “Experiences in Model/Simulation for Early Phase or Late Phase Study Planning Aimed to Learn Key Design Elements”

Sue-Jane Wang

Pages: 462-467

Published online: 01 Jan 2012

AbstractforCommentary on “Experiences in Model/Simulation for Early Phase or Late Phase Study Planning Aimed to Learn Key Design Elements” | PDF (96.6 KB)

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Index to Volume 1

Index to Volume 1, 2009

Pages: 468-470

Published online: 01 Jan 2012

First Page PreviewforIndex to Volume 1, 2009 | PDF (42.8 KB)

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