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Volume 3, Issue 1

Statistics in Biopharmaceutical Research

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Statistics in Biopharmaceutical Research, Volume 3, Issue 1 (2011)

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Statistics in Biopharmaceutical Research, Volume 3, Issue 1 (2011)

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Article

A Group Sequential Procedure for Interim Treatment Selection

Yining Wang, K.K. Gordon Lan, Gang Li & S. Peter Ouyang

Pages: 1-13

Published online: 01 Jan 2012

AbstractforA Group Sequential Procedure for Interim Treatment Selection | PDF (679.1 KB)

86 Views
5 CrossRef citations
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Article

Chain Procedures: A Class of Flexible Closed Testing Procedures With Clinical Trial Applications

Brian A. Millen & Alex Dmitrienko

Pages: 14-30

Published online: 01 Jan 2012

AbstractforChain Procedures: A Class of Flexible Closed Testing Procedures With Clinical Trial Applications | PDF (518.3 KB)

254 Views
39 CrossRef citations
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Article

Tukey’s Contrast Test Versus Two-Sample Test in a Dose-Response Clinical Trial

Girish Aras, Allen Xue & Thomas Liu

Pages: 31-39

Published online: 01 Jan 2012

AbstractforTukey’s Contrast Test Versus Two-Sample Test in a Dose-Response Clinical Trial | PDF (466.1 KB)

100 Views
3 CrossRef citations
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Article

Estimating the Dose-Response Pattern by the Maximal Contrast Type Test Approach

Chihiro Hirotsu, Shoichi Yamamoto & Ludwig A. Hothorn

Pages: 40-53

Published online: 01 Jan 2012

AbstractforEstimating the Dose-Response Pattern by the Maximal Contrast Type Test Approach | PDF (469.2 KB)

58 Views
6 CrossRef citations
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Article

Adding Subjects or Adding Measurements in Repeated Measurement Studies Under Financial Constraints

Song Zhang & Chul Ahn

Pages: 54-64

Published online: 01 Jan 2012

AbstractforAdding Subjects or Adding Measurements in Repeated Measurement Studies Under Financial Constraints | PDF (2.9 MB)

63 Views
4 CrossRef citations
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Article

Sample Size Calculation for Clustered Binary Data with Sign Tests Using Different Weighting Schemes

Chul Ahn, Fan Hu & William R. Schucany

Pages: 65-72

Published online: 01 Jan 2012

AbstractforSample Size Calculation for Clustered Binary Data with Sign Tests Using Different Weighting Schemes | PDF (299 KB)

83 Views
5 CrossRef citations
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Article

Handling Dropouts in a Multiple-Attacks Migraine Study

James Kost & Xiaoyin (Frank) Fan

Pages: 73-86

Published online: 01 Jan 2012

AbstractforHandling Dropouts in a Multiple-Attacks Migraine Study | PDF (2 MB)

46 Views
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Article

Testing Noninferiority Through Generalized p-values

Mark A. Gamalo & Ram C. Tiwari

Pages: 87-96

Published online: 01 Jan 2012

AbstractforTesting Noninferiority Through Generalized p-values | PDF (968.3 KB)

210 Views
1 CrossRef citations
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Article

Comparing Tumor Rates in Current and Historical Control Groups in Rodent Cancer Bioassays

Gregg E. Dinse & Shyamal D. Peddada

Pages: 97-105

Published online: 01 Jan 2012

AbstractforComparing Tumor Rates in Current and Historical Control Groups in Rodent Cancer Bioassays | PDF (299.5 KB)

59 Views
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