Statistics in Biopharmaceutical Research, Volume 4, Issue 1 (2012)

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Statistics in Biopharmaceutical Research, Volume 4, Issue 1 (2012)

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Original Articles

Article
Statistical Approaches to Analyzing HIV-1 Neutralizing Antibody Assay Data
Xuesong Yu, Peter B. Gilbert, Catarina E. Hioe, Susan Zolla-Pazner & Steven G. Self
Pages: 1-13
Published online: 24 May 2012
AbstractforStatistical Approaches to Analyzing HIV-1 Neutralizing Antibody Assay Data | Full Text | References | PDF (867.7 KB) | Supplemental
  • 301 Views
  • 21 CrossRef citations
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Article
Evaluation of Toxicological Studies Using a Nonparametric Shirley-Type Trend Test for Comparing Several Dose Levels with a Control Group
Frank Konietschke & Ludwig A. Hothorn
Pages: 14-27
Published online: 24 May 2012
AbstractforEvaluation of Toxicological Studies Using a Nonparametric Shirley-Type Trend Test for Comparing Several Dose Levels with a Control Group | Full Text | References | PDF (386.2 KB)
  • 259 Views
  • 10 CrossRef citations
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Article
A Generalized Pivotal Quantity Approach to the Parametric Tolerance Interval Test for Dose Content Uniformity Batch Testing
Richard A. Lewis & Steven J. Novick
Pages: 28-36
Published online: 24 May 2012
AbstractforA Generalized Pivotal Quantity Approach to the Parametric Tolerance Interval Test for Dose Content Uniformity Batch Testing | Full Text | References | PDF (243.6 KB)
  • 149 Views
  • 2 CrossRef citations
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Article
R Estimates and Associated Inferences for Mixed Models With Covariates in a Multicenter Clinical Trial
M. Mushfiqur Rashid, Joseph W. McKean & John D. Kloke
Pages: 37-49
Published online: 24 May 2012
AbstractforR Estimates and Associated Inferences for Mixed Models With Covariates in a Multicenter Clinical Trial | Full Text | References | PDF (251.9 KB)
  • 196 Views
  • 5 CrossRef citations
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Article
Impact of Length Difference in Risk and Comparison Windows: A Cautionary Note
Xiaoming Li, Ivan S.F. Chan & A. Lawrence Gould
Pages: 50-56
Published online: 24 May 2012
AbstractforImpact of Length Difference in Risk and Comparison Windows: A Cautionary Note | Full Text | References | PDF (182 KB)
  • 76 Views
  • 1 CrossRef citations
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Article
A Multivariate Williams-Type Trend Procedure
Mario Hasler & Ludwig A. Hothorn
Pages: 57-65
Published online: 24 May 2012
AbstractforA Multivariate Williams-Type Trend Procedure | Full Text | References | PDF (163.6 KB)
  • 167 Views
  • 11 CrossRef citations
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Article
Analysis of Family Data Collected under A General Proband Sampling Scheme
Yougui Wu & Yiliang Zhu
Pages: 66-75
Published online: 24 May 2012
AbstractforAnalysis of Family Data Collected under A General Proband Sampling Scheme | Full Text | References | PDF (163.7 KB)
  • 60 Views
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Article
Bayesian Sample Size Estimates for One Sample Test in Clinical Trials With Dichotomous and Countable Outcomes
Boris G. Zaslavsky
Pages: 76-85
Published online: 24 May 2012
AbstractforBayesian Sample Size Estimates for One Sample Test in Clinical Trials With Dichotomous and Countable Outcomes | Full Text | References | PDF (212 KB) | Supplemental
  • 210 Views
  • 6 CrossRef citations
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Article
Adaptive Patient Population Selection Design in Clinical Trials
Hui Quan, Dongli Zhou, Pierre Mancini, Yi He & Gary Koch
Pages: 86-99
Published online: 24 May 2012
AbstractforAdaptive Patient Population Selection Design in Clinical Trials | Full Text | References | PDF (223.3 KB)
  • 222 Views
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