Statistics in Biopharmaceutical Research, Volume 4, Issue 2 (2012)

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Statistics in Biopharmaceutical Research, Volume 4, Issue 2 (2012)

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Special Issue on Nonclinical Statistics

Original Articles

Article
Introduction to Special Issue on Nonclinical Biopharmaceutical Statistics
Stan Altan & Timothy L. Schofield
Pages: 100-101
Published online: 10 Aug 2012
CitationforIntroduction to Special Issue on Nonclinical Biopharmaceutical Statistics | Full Text | PDF (42.3 KB)
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Article
A Bayesian Approach to Show Assay Equivalence with Replicate Measurements Over a Specified Response Range
Steven Novick, Karen Chiswell & John Peterson
Pages: 102-117
Published online: 10 Aug 2012
AbstractforA Bayesian Approach to Show Assay Equivalence with Replicate Measurements Over a Specified Response Range | Full Text | References | PDF (3.2 MB)
  • 213 Views
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Article
Should We Assess Tumorigenicity With the Peto or Poly-k Test?
Ralph L. Kodell
Pages: 118-124
Published online: 10 Aug 2012
AbstractforShould We Assess Tumorigenicity With the Peto or Poly-k Test? | Full Text | References | PDF (213.8 KB)
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Article
Quality Considerations in the Establishment of Specifications for Pharmaceuticals
Dennis Sandell & Terrence Tougas
Pages: 125-135
Published online: 10 Aug 2012
AbstractforQuality Considerations in the Establishment of Specifications for Pharmaceuticals | Full Text | References | PDF (956.7 KB)
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Article
Evaluating Two PTI Test Procedures for Control of Delivered Dose Uniformity for Aerosol Products
Yan Lan, C. Thomas Lin & Hongyuan Cao
Pages: 136-148
Published online: 10 Aug 2012
AbstractforEvaluating Two PTI Test Procedures for Control of Delivered Dose Uniformity for Aerosol Products | Full Text | References | PDF (2.2 MB)
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Article
Generalized Semilinear Canonical Correlation Analysis Applied to the Analysis of Electroencephalogram (EEG) Data
P. Brain, F. Strimenopoulou & M. Ivarsson
Pages: 149-161
Published online: 10 Aug 2012
AbstractforGeneralized Semilinear Canonical Correlation Analysis Applied to the Analysis of Electroencephalogram (EEG) Data | Full Text | References | PDF (983.3 KB)
  • 133 Views
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Article
Evaluations of Parallelism Testing Methods Using ROC Analysis
Harry Yang & Lanju Zhang
Pages: 162-173
Published online: 10 Aug 2012
AbstractforEvaluations of Parallelism Testing Methods Using ROC Analysis | Full Text | References | PDF (1 MB)
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Article
On Response-Constrained Optimal Experimental Conditions in a Polynomial Mixed Model Setting
Qianqiu Li, Hong Shen, Bin Lin, Ken Goldberg & Bill Pikounis
Pages: 174-184
Published online: 10 Aug 2012
AbstractforOn Response-Constrained Optimal Experimental Conditions in a Polynomial Mixed Model Setting | Full Text | References | PDF (414.1 KB)
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Article
A Linear Prediction Rule Based on Ensemble Classifiers for Non-Genotoxic Carcinogenicity
Nandini Raghavan, Alex Y. Nie, Michael McMillian & Dhammika Amaratunga
Pages: 185-193
Published online: 10 Aug 2012
AbstractforA Linear Prediction Rule Based on Ensemble Classifiers for Non-Genotoxic Carcinogenicity | Full Text | References | PDF (933.6 KB)
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Article
Data Analysis Approaches for High Content Screening
Amir A. Handzel, Andy Liaw, Frank P. Stefano, Grace K.Y. Chan, Alexander A. Szewczak & Francesca Santini
Pages: 194-204
Published online: 10 Aug 2012
AbstractforData Analysis Approaches for High Content Screening | Full Text | References | PDF (8.7 MB)
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Article
A Meta-Analytical Framework to Include Historical Data in Allometric Scaling
Luc Bijnens, An Van den Bergh, Vikash Sinha, Helena Geys, Geert Molenberghs, Tobias Verbeke, Adetayo Kasim, Roel Straetemans, Filip De Ridder & Claire Balmain-Mackie
Pages: 205-215
Published online: 10 Aug 2012
AbstractforA Meta-Analytical Framework to Include Historical Data in Allometric Scaling | Full Text | References | PDF (1 MB)
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