Galinsosides A and B, bioactive flavanone glucosides from Galinsoga parviflora

Abstract

Galinsosides A (1) and B (2), new flavanone glucosides together with two known flavanones, 7,3′,4′-trihydroxyflavanone (3) and 3,5,7,3′,4′-pentahydroxyflavanone (4) have been isolated from an ethyl acetate- soluble fraction of Galinsoga parviflora. Their structures were assigned on the basis of spectral studies. Compound 1 showed significant antioxidant and urease inhibitory activity while compound 2 was moderately active. On the other hand, 2 showed inhibitory potential against α-glucosidase.

Keywords::

• Galinsoga parviflora
• Galinsoside A
• Galinsoside B
• Antioxidant activity
• Enzyme inhibition
• Urease
• α-glucosidase

Acknowledgements

Authors are thankful to the Higher Education Commission of Pakistan providing financial support for spectroscopic analysis of compounds at International Centre for Chemical Sciences, HEJ Research Institute of Chemistry, University of Karachi.

Declaration of interest: The authors report no conflicts of interest.