Declaration of interest
B Tomlinson has received research funding from Amgen, AstraZeneca, Merck Serono, Merck Sharp & Dohme, Novartis, Pfizer and Roche. B Tomlinson has served as a consultant/advisor/speaker for Amgen, AstraZeneca, Merck Serono and Sanofi. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.