Expert Opinion on Drug Metabolism & Toxicology, Volume 12, Issue 11 (2016)

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Expert Opinion on Drug Metabolism & Toxicology, Volume 12, Issue 11 (2016)

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Editorial

Editorial
Metabolomic profiling for early cancer detection: current status and future prospects
Vicki J. Hwang & Robert H. Weiss
Pages: 1263-1265
Published online: 23 Sep 2016
First Page PreviewforMetabolomic profiling for early cancer detection: current status and future prospects | Full Text | References | PDF (294.8 KB)
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Editorial
Effects of glucose-lowering drugs on cardiovascular outcomes in patients with type 2 diabetes
Brian Tomlinson, Miao Hu, Yuzhen Zhang, Paul Chan & Zhong-Min Liu
Pages: 1267-1271
Published online: 19 Sep 2016
First Page PreviewforEffects of glucose-lowering drugs on cardiovascular outcomes in patients with type 2 diabetes | Full Text | References | PDF (553.7 KB)
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Original Research

Article
Simple physicochemical properties related with lipophilicity, polarity, molecular size and ionization status exert significant impact on the transfer of drugs and chemicals into human breast milk
George Vasios, Aggeliki Kosmidi, Olga-Ioanna Kalantzi, Anna Tsantili-Kakoulidou, Nikolaos Kavantzas, Stamatios Theocharis & Constantinos Giaginis
Pages: 1273-1278
Published online: 06 Sep 2016
AbstractforSimple physicochemical properties related with lipophilicity, polarity, molecular size and ionization status exert significant impact on the transfer of drugs and chemicals into human breast milk | Full Text | References | PDF (921.7 KB) | Supplemental
  • 311 Views
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Review

Review
Ocular surface toxicity from glaucoma topical medications and associated preservatives such as benzalkonium chloride (BAK)
Alberto Aguayo Bonniard, Jacky Y. Yeung, Clara C. Chan & Catherine M. Birt
Pages: 1279-1289
Published online: 18 Jul 2016
AbstractforOcular surface toxicity from glaucoma topical medications and associated preservatives such as benzalkonium chloride (BAK) | Full Text | References | PDF (820.7 KB)
  • 698 Views
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Review
Autoimmune-like drug-induced liver injury: a review and update for the clinician
Jonathan G. Stine & Patrick G. Northup
Pages: 1291-1301
Published online: 21 Jul 2016
AbstractforAutoimmune-like drug-induced liver injury: a review and update for the clinician | Full Text | References | PDF (965.4 KB)
  • 645 Views
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Review
The role of cytochrome P450 pharmacogenomics in chronic non-cancer pain patients
Tatiana Tverdohleb, Bora Dinc, Ivana Knezevic, Kenneth D. Candido & Nebojsa Nick Knezevic
Pages: 1303-1311
Published online: 15 Jul 2016
AbstractforThe role of cytochrome P450 pharmacogenomics in chronic non-cancer pain patients | Full Text | References | PDF (807.5 KB)
  • 346 Views
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Review
The use of pharmacokinetics in dose individualization of factor VIII in the treatment of hemophilia A
Alanna McEneny-King, Alfonso Iorio, Gary Foster & Andrea N. Edginton
Pages: 1313-1321
Published online: 19 Aug 2016
AbstractforThe use of pharmacokinetics in dose individualization of factor VIII in the treatment of hemophilia A | Full Text | References | PDF (894.1 KB)
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Review
Therapeutic protein-drug interactions: plausible mechanisms and assessment strategies
Honghui Zhou & Amarnath Sharma
Pages: 1323-1331
Published online: 21 Jul 2016
AbstractforTherapeutic protein-drug interactions: plausible mechanisms and assessment strategies | Full Text | References | PDF (740.7 KB)
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Review
Vonoprazan for treatment of gastroesophageal reflux: pharmacodynamic and pharmacokinetic considerations
Edoardo Savarino, Irene Martinucci, Manuele Furnari, Chiara Romana, Gaia Pellegatta, Alessandro Moscatelli, Giorgia Bodini, Elisa Marabotto, Vincenzo Savarino, Nicola de Bortoli & Corrado Blandizzi
Pages: 1333-1341
Published online: 08 Aug 2016
AbstractforVonoprazan for treatment of gastroesophageal reflux: pharmacodynamic and pharmacokinetic considerations | Full Text | References | PDF (714.2 KB)
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Review
Intravenous immunoglobulin: pharmacological properties and use in polyneuropathies
Livia Dézsi, Zoltán Horváth & László Vécsei
Pages: 1343-1358
Published online: 22 Aug 2016
AbstractforIntravenous immunoglobulin: pharmacological properties and use in polyneuropathies | Full Text | References | PDF (1.2 MB)
  • 334 Views
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Drug Evaluation

Article
Pharmacokinetic drug evaluation of albutrepenonacog alfa (CSL654) for the treatment of hemophilia
Massimo Morfini
Pages: 1359-1365
Published online: 02 Oct 2016
AbstractforPharmacokinetic drug evaluation of albutrepenonacog alfa (CSL654) for the treatment of hemophilia | Full Text | References | PDF (565.4 KB)
  • 440 Views
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Article
Pharmacokinetic and pharmacodynamic drug evaluation of tofogliflozin for the treatment of type 2 diabetes
Kalliopi Pafili, Efstratios Maltezos & Nikolaos Papanas
Pages: 1367-1380
Published online: 08 Sep 2016
AbstractforPharmacokinetic and pharmacodynamic drug evaluation of tofogliflozin for the treatment of type 2 diabetes | Full Text | References | PDF (1 MB)
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Article
Pharmacokinetic and pharmacodynamic evaluation of ibrutinib for the treatment of chronic lymphocytic leukemia: rationale for lower doses
Prithviraj Bose, Varsha V. Gandhi & Michael J. Keating
Pages: 1381-1392
Published online: 11 Oct 2016
AbstractforPharmacokinetic and pharmacodynamic evaluation of ibrutinib for the treatment of chronic lymphocytic leukemia: rationale for lower doses | Full Text | References | PDF (1.2 MB)
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