Anti-inflammatory actions of lipoxins

Abstract

Efforts to understand and harness the potent anti-inflammatory and immunomodulating properties of the endogenous lipid mediators lipoxin A₄ (LXA₄), lipoxin B₄ (LXB₄) and the aspirin-triggered lipoxins, have resulted in a number of patent applications by both academic research groups and pharmaceutical companies. The patents cover the anti-inflammatory properties of lipoxins across a range of diseases with components of inflammation.

Keywords::

• anti-inflammatory
• aspirin
• inflammation
• lipoxin
• neutrophil
• stable analogue