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Abstract
For years, phosphodiesterase type 5 inhibitors have been used for the treatment of erectile dysfunctions. Due to the similarities between male and female sexual response, several studies have assessed the effects of sildenafil citrate (Viagra®) in women affected by female sexual arousal disorder. The results are still conflicting and the drug is not devoid of adverse effects. Furthermore, female sexual arousal disorder is a heterogeneous condition whose underlying causes are difficult to diagnose and appropriate treatment requires a thorough sexual, psychological, and medical history along with specialist consultations. The clinician should pursue a global approach to the patient with sexual difficulties, while non-hormonal treatment such as phosphodiesterase type 5 inhibitors (ie, sildenafil citrate) should be kept as the last option.
Author contributions
IP, GLM, and AG have substantially contributed to the interpretation of data and literature analysis. They also concurred to design, prepare, draft, and revise the final version of the manuscript. RM has substantially contributed to critical literature revision, preparation, drafting, and revising the final version of the manuscript. He also gave extremely important intellectual support and ensured the general supervision of the research group. All authors read and approved the final manuscript.
Disclosure
The authors report no conflicts of interest in this work.