Advanced search
Publication Cover
Endocrine Research Volume 21, 1995 - Issue 1-2
Submit an article Journal homepage
6
Views
1
CrossRef citations to date
0
Altmetric
Original Article

Cortisol: A tool to study aldosterone biosynthesis in rats

Laura Matković Departamento de Química Biológica, Facultad de Cs. Exactas y Naturales-UBA and PRHOM-CONICET, Buenos, Aires-1428, Argentina
,
Celso E. Gomez-sanchez Department of Internal Medicine, Harry S Truman Veterans' Hospital, University of Missouri, Columbia, MO, 65201, USA
,
Carlos P. Lantos Departamento de Química Biológica, Facultad de Cs. Exactas y Naturales-UBA and PRHOM-CONICET, Buenos, Aires-1428, Argentina
&
Eduardo N. Cozza Departamento de Química Biológica, Facultad de Cs. Exactas y Naturales-UBA and PRHOM-CONICET, Buenos, Aires-1428, Argentina
Pages 471-475 | Published online: 07 Jul 2009
 
Sample our Medicine, Dentistry, Nursing & Allied Health journals, sign in here to start your FREE access for 14 days

Abstract

Corticosterone (B) and 18-hydroxy-11-deoxycorticosterone (18OHDOC) but not 11-deoxycorticosterone (DOC) displaced cortisol (F) specifically bound to rat adrenal mitochondria. F competitively inhibited aldosterone formation from B, 18OHB and 18OHDOC but did not inhibit conversions of DOC to B or 18OHDOC. High concentrations of DOC increased its conversion to 18OHDOC rather than B.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.