Abstract
Periodic leg movements in sleep (PLMS) has been reported in patients with fibromyalgia. We carried out overnight polysomnography to determine the prevalence of PLMS in 15 inpatients with fibromyalgia, 7 of whom (47%) were discovered to have PLMS. Patients with PLMS and fibromyalgia did not clinically differ from patients with only fibromyalgia. Polysomnography was necessary to establish the Presence of PLMS. The recognition of LMS in patients with fibromyalgia is consequential because PLMS is usually treated with clonazepam, and fibromyalgia is often treated with antidepressants. In addition, antidepressants may precipitate or intensify PLMS. Polysomnography should be considered to detect PLMS in patients with fibromyalgia; patients with PLMS should be examined for fibromyalgia.