Abstract
In this study, some N-[4-(Benzothiazole-2-yl) phenyl]-2-aryloxyacetamide derivatives were prepared by reacting N-[4-(benzothiazole-2yl)phenyl]-2-chloroacetamide and different substituent phenol or thiophenol derivatives. The anticancer activities of the compounds obtained were investigated. It was observed that some of the compounds, namely 25 and 38, showed notable anticancer activity.
Acknowledgements
This work was supported by the Commission of Scientific Research Projects of Eskisehir Osmangazi University (ESOGU/200819010). The authors gratefully acknowledge the financial support by Eskişehir Osmangazi University. Authors also would like to thank to National Cancer Institue (NCI), Bethesda, MD, USA for in vitro screening of our compounds in human cancer cell lines.
Declaration of interest
The authors report no conflicts of interest.