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Pharmaceutical Biology Volume 38, 2000 - Issue 1
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Research Article

The Natural Abundance Of L-Canavanine, An Active Anticancer Agent, in Alfalfa, Medicago Sativa (L.)

Gerald A. Rosenthal Laboratory of Biochemical Ecology, University of Kentucky, Lexington, USA
&
Palesa Nkomo Laboratory of Biochemical Ecology, University of Kentucky, Lexington, USA
Pages 1-6 | Published online: 10 Jan 2011

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Kelly Cristine da Silva Rodrigues-Corrêa & Arthur Germano Fett-Neto. (2019) Abiotic Stresses and Non-Protein Amino Acids in Plants. Critical Reviews in Plant Sciences 38:5-6, pages 411-430.
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Y. H. Taufiq-Yap, T. H. Peh, G. C. L. Ee, M. Rahmani, M. A. Sukari, A. M. Ali & R. Muse. (2007) A new cytotoxic carbazole alkaloid from . Natural Product Research 21:9, pages 810-813.
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Aimee K. Bence & Peter A. Crooks. (2003) The Mechanism of l-Canavanine Cytotoxicity: Arginyl tRNA Synthetase as a Novel Target for Anticancer Drug Discovery. Journal of Enzyme Inhibition and Medicinal Chemistry 18:5, pages 383-394.
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Articles from other publishers (23)

Evan B. Craine, Muhammet Şakiroğlu, Spencer Barriball, Tessa E. Peters & Brandon Schlautman. (2024) Perennial Baki™ Bean Safety for Human Consumption: Evidence from an Analysis of Heavy Metals, Folate, Canavanine, Mycotoxins, Microorganisms and Pesticides. Molecules 29:8, pages 1777.
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Sharad Vats, Chhavi Kaushal, Michael P. Timko & Showkat Ahmad Ganie. (2024) Uraria picta: A review on its ethnobotany, bioactive compounds, pharmacology and commercial relevance. South African Journal of Botany 167, pages 333-354.
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Mokgadi M. Hlongwane, Mustapha Mohammed, Ntebogeng S. Mokgalaka & Felix D. Dakora. (2023) The Potential of Rhizobacteria to Mitigate Abiotic Stress in Lessertia frutescens. Plants 12:1, pages 196.
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Nóra Gampe, Lilla Ladocsi, Ida Fejős, Imre Boldizsár, András Darcsi & Szabolcs Béni. (2022) Enantioseparation and quantitative determination of two homologous beta amino acids found in Fabaceae plants. Journal of Chromatography A 1675, pages 463089.
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Bahman Fazeli-Nasab & Fatemeh Bidarnamani. (2022) Medicinal Plants and Herbal Compounds: Cancer Prevention and Treatment. Plant Biotechnology Persa 4:1, pages 25-36.
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Azadeh Hamedi, Maryam Bayat, Yahya Asemani & Zahra Amirghofran. (2022) A review of potential anti-cancer properties of some selected medicinal plants grown in Iran. Journal of Herbal Medicine 33, pages 100557.
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Vivek P. Chavda, Aayushi B. Patel, Kavya J. Mistry, Suresh F. Suthar, Zhuo-Xun Wu, Zhe-Sheng Chen & Kaijian Hou. (2022) Nano-Drug Delivery Systems Entrapping Natural Bioactive Compounds for Cancer: Recent Progress and Future Challenges. Frontiers in Oncology 12.
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Alena Aliashkevich, Matthew Howell, Pamela J. B. Brown & Felipe Cava. (2021) d ‐canavanine affects peptidoglycan structure, morphogenesis and fitness in Rhizobiales . Environmental Microbiology 23:10, pages 5823-5836.
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Norizam Salamt, Ruszymah Binti Haji Idrus, Mohd Izhar Ariff Mohd Kashim & Mohd Helmy Mokhtar. (2021) Anticancer, antiplatelet, gastroprotective and hepatoprotective effects of camel urine: A scoping review. Saudi Pharmaceutical Journal 29:7, pages 740-750.
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K. Karl Compton & Birgit E. Scharf. (2021) Rhizobial Chemoattractants, the Taste and Preferences of Legume Symbionts. Frontiers in Plant Science 12.
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Eliseo Ruiz BedollaBriceida Lopez MartinezIsrael Parra Ortega. (2021) ROLE OF NON-PROTEIN AMINO ACIDS IN AUTOIMMUNE DISEASES. INDIAN JOURNAL OF APPLIED RESEARCH, pages 9-13.
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Hany S. Mahmoud, Wael M. Elsaed & Sami A. Gabr. (2019) Camel Urotherapy and Hepatoprotective Effects Against Carbon Tetrachloride-induced Liver Toxicity. International Journal of Pharmacology 15:6, pages 696-705.
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Simon Vlad Luca, Kazimierz Głowniak & Krystyna Skalicka‐Woźniak. 2007. Encyclopedia of Analytical Chemistry. Encyclopedia of Analytical Chemistry 1 45 .
Majid Asadi-Samani, Mahmoud Rafieian-Kopaei, Zahra Lorigooini & Hedayatollah Shirzad. (2018) A screening of growth inhibitory activity of Iranian medicinal plants on prostate cancer cell lines. BioMedicine 8:2, pages 8.
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Paweł Staszek, Leslie A. Weston, Katarzyna Ciacka, Urszula Krasuska & Agnieszka Gniazdowska. (2017) l-Canavanine: How does a simple non-protein amino acid inhibit cellular function in a diverse living system?. Phytochemistry Reviews 16:6, pages 1269-1282.
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Syed Rizwan Ahamad, Abdul Qader Alhaider, Mohammad Raish & Faiyaz Shakeel. (2017) Metabolomic and elemental analysis of camel and bovine urine by GC–MS and ICP–MS. Saudi Journal of Biological Sciences 24:1, pages 23-29.
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Tatyana Dzimbova & Tamara Pajpanova. 2017. L-Arginine in Clinical Nutrition. L-Arginine in Clinical Nutrition 55 70 .
Cristina Megías, Isabel Cortés-Giraldo, Julio Girón-Calle, Javier Vioque & Manuel Alaiz. (2015) Determination of l-canavanine and other free amino acids in Vicia disperma (Fabaceae) seeds by precolumn derivatization using diethyl ethoxymethylenemalonate and reversed-phase high-performance liquid chromatography. Talanta 131, pages 95-98.
Crossref
Steven M. Colegate, Dale R. Gardner & Stephen T. Lee. 2015. Handbook of Food Chemistry. Handbook of Food Chemistry 753 783 .
Krystyna Skalicka‐Woźniak & Kazimierz Głowniak. 2007. Encyclopedia of Analytical Chemistry. Encyclopedia of Analytical Chemistry 1 26 .
Steven M. Colegate, Dale R. Gardner & Stephen T. Lee. 2015. Handbook of Food Chemistry. Handbook of Food Chemistry 1 24 .
Eric Yarnell & Kathy Abascal. (2008) Lupus Erythematosus and Herbal Medicine. Alternative and Complementary Therapies 14:1, pages 9-12.
Crossref
S. Ekanayake, K. Skog & N.-G. Asp. (2007) Canavanine content in sword beans (Canavalia gladiata): Analysis and effect of processing. Food and Chemical Toxicology 45:5, pages 797-803.
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