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Acta Oto-Laryngologica Volume 126, 2006 - Issue 7
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ORIGINAL ARTICLE: INNER EAR

Triamcinolone acetonide protects auditory hair cells from 4-hydroxy-2,3-nonenal (HNE) ototoxicity in vitro

Jose GuzmanUniversity of Miami Ear Institute, Department of Otolaryngology, Miller School of Medicine University of Miami, Miami, FL, USA;Department of Otolaryngology, University of Bogotá, Bogotá, Columbia
,
Jose RuizUniversity of Miami Ear Institute, Department of Otolaryngology, Miller School of Medicine University of Miami, Miami, FL, USA
,
Adrien A. EshraghiUniversity of Miami Ear Institute, Department of Otolaryngology, Miller School of Medicine University of Miami, Miami, FL, USA
,
Marek PolakUniversity of Miami Ear Institute, Department of Otolaryngology, Miller School of Medicine University of Miami, Miami, FL, USA;MED-EL, Medical Electronics GmbH, Innsbruck, Austria
,
Carolyn GarnhamMED-EL, Medical Electronics GmbH, Innsbruck, Austria
,
Thomas J. BalkanyUniversity of Miami Ear Institute, Department of Otolaryngology, Miller School of Medicine University of Miami, Miami, FL, USA
&
Thomas R. Van De WaterUniversity of Miami Ear Institute, Department of Otolaryngology, Miller School of Medicine University of Miami, Miami, FL, USACorrespondence[email protected]
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Pages 685-690 | Received 07 Oct 2005, Accepted 17 Nov 2005, Published online: 27 Feb 2017

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Thu Nhan Nguyen, So-Yeol Yoo, Warisraporn Tangchang, Jae-Young Lee, Hwa-Young Son & Jeong-Sook Park. (2023) Sustained delivery of triamcinolone acetonide from a thermosensitive microemulsion gel system for the treatment of sensorineural hearing loss. Drug Delivery 30:1.
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Enrique R. Perez, Dana R. Libman & Thomas R. van de Water. (2012) Local drug delivery for inner ear therapy. Audiological Medicine 10:1, pages 1-20.
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Articles from other publishers (12)

Chih-Hao Chen, Ching-Yuan Wang, Meng-Yu Cheng, Wen-Hsin Hsih, Ni Tien, Chia-Huei Chou, Po-Chang Lin, Chih-Yu Chi, Mao-Wang Ho & Min-Chi Lu. (2022) Definite therapy of mixed infection alleviates refractory dilemma of adult chronic suppurative otitis media. Journal of Microbiology, Immunology and Infection 55:6, pages 1283-1292.
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P.W. Harvey. 2018. Comprehensive Toxicology. Comprehensive Toxicology 165 185 .
Stefania Goncalves, Enrique Perez, Esperanza Bas, Christine T. Dinh & Thomas R. Van De Water. 2018. Inflammatory Mechanisms in Mediating Hearing Loss. Inflammatory Mechanisms in Mediating Hearing Loss 165 187 .
Esperanza Bas, Jorge Bohorquez, Stefania Goncalves, Enrique Perez, Christine T. Dinh, Carolyn Garnham, Roland Hessler, Adrien A. Eshraghi & Thomas R. Van De Water. (2016) Electrode array-eluted dexamethasone protects against electrode insertion trauma induced hearing and hair cell losses, damage to neural elements, increases in impedance and fibrosis: A dose response study. Hearing Research 337, pages 12-24.
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Elisabeth Engleder, Clemens Honeder, Julia Klobasa, Michael Wirth, Christoph Arnoldner & Franz Gabor. (2014) Preclinical evaluation of thermoreversible triamcinolone acetonide hydrogels for drug delivery to the inner ear. International Journal of Pharmaceutics 471:1-2, pages 297-302.
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Xiaoping Du, Wei Li, Xinsheng Gao, Matthew B. West, W. Mark Saltzman, Christopher J. Cheng, Charles Stewart, Jie Zheng, Weihua Cheng & Richard D. Kopke. (2013) Regeneration of mammalian cochlear and vestibular hair cells through Hes1/Hes5 modulation with siRNA. Hearing Research 304, pages 91-110.
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Shuho Tanaka, Keiji Tabuchi, Tomofumi Hoshino, Hidekazu Murashita, Shigeki Tsuji & Akira Hara. (2010) Protective effects of exogenous GM-1 ganglioside on acoustic injury of the mouse cochlea. Neuroscience Letters 473:3, pages 237-241.
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P.W. Harvey. 2010. Comprehensive Toxicology. Comprehensive Toxicology 265 289 .
Yoko Miura & Johann Roider. (2009) Triamcinolone acetonide prevents oxidative stress-induced tight junction disruption of retinal pigment epithelial cells. Graefe's Archive for Clinical and Experimental Ophthalmology 247:5, pages 641-649.
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G Michael Wall, David W. Stroman, Peter S. Roland & Joseph Dohar. (2009) Ciprofloxacin 0.3%/Dexamethasone 0.1% Sterile Otic Suspension for the Topical Treatment of Ear Infections. Pediatric Infectious Disease Journal 28:2, pages 141-144.
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Andrew Forge & Thomas R. Van De Water. 2008. Hair Cell Regeneration, Repair, and Protection. Hair Cell Regeneration, Repair, and Protection 199 255 .
Adrien A. Eshraghi, Jing Wang, Eelam Adil, Jiao He, Azel Zine, Michael Bublik, Christophe Bonny, Jean-Luc Puel, Thomas J. Balkany & Thomas R. Van De Water. (2007) Blocking c-Jun-N-terminal kinase signaling can prevent hearing loss induced by both electrode insertion trauma and neomycin ototoxicity. Hearing Research 226:1-2, pages 168-177.
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