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Xenobiotica
the fate of foreign compounds in biological systems
Volume 47, 2017 - Issue 4
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Xenobiotic Transporters

Probenecid, an organic anion transporter 1 and 3 inhibitor, increases plasma and brain exposure of N-acetylcysteine

Fanuel T. HagosDepartment of Pharmaceutical Sciences, and
,
Monica J. DaoodDepartment of Pharmacy and Therapeutics, Center for Clinical Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, PA, USA,
,
Jacob A. OcqueDepartment of Pharmacy and Therapeutics, Center for Clinical Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, PA, USA,
,
Thomas D. NolinDepartment of Pharmacy and Therapeutics, Center for Clinical Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, PA, USA,
,
Hulya BayirDepartment of Critical Care Medicine and;Safar Center for Resuscitation Research, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA, and ;Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA, USA
,
Samuel M. PoloyacDepartment of Pharmaceutical Sciences, and
,
Patrick M. KochanekDepartment of Critical Care Medicine and;Safar Center for Resuscitation Research, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA, and ;Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA, USA
,
Robert S. B. ClarkDepartment of Critical Care Medicine and;Safar Center for Resuscitation Research, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA, and ;Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA, USA
&
Philip E. EmpeyDepartment of Pharmacy and Therapeutics, Center for Clinical Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, PA, USA, Correspondence[email protected]
 show all
Pages 346-353 | Received 17 Mar 2016, Accepted 05 May 2016, Published online: 09 Jun 2016

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Yuan Zhou, Han-dong Wang, Xiao-ming Zhou, Jiang Fang, Lin Zhu & Ke Ding. (2018) N-acetylcysteine amide provides neuroprotection via Nrf2-ARE pathway in a mouse model of traumatic brain injury. Drug Design, Development and Therapy 12, pages 4117-4127.
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Solomon M Adams, Yvette P Conley, Amy K Wagner, Ruchira M Jha, Robert SB Clark, Samuel M Poloyac, Patrick M Kochanek & Philip E Empey. (2017) The pharmacogenomics of Severe Traumatic Brain Injury. Pharmacogenomics 18:15, pages 1413-1425.
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