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Xenobiotica
the fate of foreign compounds in biological systems
Volume 49, 2019 - Issue 5
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General Xenobiochemistry

Suitable albumin concentrations for enhanced drug oxidation activities mediated by human liver microsomal cytochrome P450 2C9 and other forms predicted with unbound fractions and partition/distribution coefficients of model substrates

Kanami ShimuraLaboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University, Machida, Tokyo, JapanView further author information
,
Norie MurayamaLaboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University, Machida, Tokyo, JapanView further author information
,
Saki TanakaLaboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University, Machida, Tokyo, JapanView further author information
,
Shunsuke OnozekiLaboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University, Machida, Tokyo, JapanView further author information
&
Hiroshi YamazakiLaboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University, Machida, Tokyo, JapanCorrespondence[email protected]
ORCID Iconhttp://orcid.org/0000-0002-1068-4261View further author information
ORCID Icon
Pages 557-562 | Received 27 Apr 2018, Accepted 27 May 2018, Published online: 18 Jun 2018

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Michel Bteich, Patrick Poulin & Sami Haddad. (2019) The potential protein-mediated hepatic uptake: discussion on the molecular interactions between albumin and the hepatocyte cell surface and their implications for the in vitro-to-in vivo extrapolations of hepatic clearance of drugs. Expert Opinion on Drug Metabolism & Toxicology 15:8, pages 633-658.
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Articles from other publishers (7)

Makiko Shimizu, Riku Hayasaka, Yusuke Kamiya & Hiroshi Yamazaki. (2022) Trivariate Linear Regression and Machine Learning Prediction of Possible Roles of Efflux Transporters in Estimated Intestinal Permeability Values of 301 Disparate Chemicals. Biological and Pharmaceutical Bulletin 45:8, pages 1142-1157.
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Yusuke Kamiya, Asuka Omura, Riku Hayasaka, Rie Saito, Izumi Sano, Kentaro Handa, Junya Ohori, Masato Kitajima, Fumiaki Shono, Kimito Funatsu & Hiroshi Yamazaki. (2021) Prediction of permeability across intestinal cell monolayers for 219 disparate chemicals using in vitro experimental coefficients in a pH gradient system and in silico analyses by trivariate linear regressions and machine learning. Biochemical Pharmacology 192, pages 114749.
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Monica Butnariu & Marian Butu. 2021. Phytomedicine. Phytomedicine 343 376 .
Jung-Hwan Kwon, Hyun-Jeoung Lee & Beate I. Escher. (2020) Bioavailability of hydrophobic organic chemicals on an in vitro metabolic transformation using rat liver S9 fraction. Toxicology in Vitro 66, pages 104835.
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Yusuke Kamiya, Hiroka Takaku, Rio Yamada, Chisato Akase, Yuto Abe, Yuko Sekiguchi, Norie Murayama, Makiko Shimizu, Masato Kitajima, Fumiaki Shono, Kimito Funatsu & Hiroshi Yamazaki. (2020) Determination and prediction of permeability across intestinal epithelial cell monolayer of a diverse range of industrial chemicals/drugs for estimation of oral absorption as a putative marker of hepatotoxicity. Toxicology Reports 7, pages 149-154.
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Seohyun (Claudia) Choi, Michael Casias, Danielle Tompkins & Jimmy Gonzalez. 2020. A Worldwide Yearly Survey of New Data in Adverse Drug Reactions. A Worldwide Yearly Survey of New Data in Adverse Drug Reactions 317 336 .
Yusuke Kamiya, Shohei Otsuka, Tomonori Miura, Hiroka Takaku, Rio Yamada, Mayuko Nakazato, Hitomi Nakamura, Sawa Mizuno, Fumiaki Shono, Kimito Funatsu & Hiroshi Yamazaki. (2018) Plasma and Hepatic Concentrations of Chemicals after Virtual Oral Administrations Extrapolated Using Rat Plasma Data and Simple Physiologically Based Pharmacokinetic Models. Chemical Research in Toxicology 32:1, pages 211-218.
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