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Xenobiotica

the fate of foreign compounds in biological systems

Volume 29, 1999 - Issue 11

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Research Article

In vitro metabolism of mifepristone (RU-486) in rat, monkey and human hepatic S9 fractions: identification of three new mifepristone metabolites

W. N. Wu Department of Drug Metabolism, Division of Preclinical Development, The R. W. Johnson Pharmaceutical Research Institute, Spring House, PA 19477, USA

L. A. McKown Department of Drug Metabolism, Division of Preclinical Development, The R. W. Johnson Pharmaceutical Research Institute, Spring House, PA 19477, USA

M. D. Moyer Department of Drug Metabolism, Division of Preclinical Development, The R. W. Johnson Pharmaceutical Research Institute, Spring House, PA 19477, USA

T. B. Johannsen Department of Drug Metabolism, Division of Preclinical Development, The R. W. Johnson Pharmaceutical Research Institute, Spring House, PA 19477, USA

A. R. Takacs Department of Drug Metabolism, Division of Preclinical Development, The R. W. Johnson Pharmaceutical Research Institute, Spring House, PA 19477, USA

Pages 1089-1100 | Published online: 22 Sep 2008

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https://doi.org/10.1080/004982599237976

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Yu-Zhu Yang, Tao Wang, Qi-Lei Chen, Hu-Biao Chen, Qian-Song He & Ya-Zhou Zhang. (2023) Identification of the Metabolites of Both Formononetin in Rat Hepatic S9 and Ononin in Rat Urine Samples and Preliminary Network Pharmacology Evaluation of Their Main Metabolites. Molecules 28:21, pages 7451.
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Paweł Szpot, Olga Wachełko, Tomasz Jurek & Marcin Zawadzki. (2022) Determination of Mifepristone (RU-486) and Its Metabolites in Maternal Blood Sample after Pharmacological Abortion. Molecules 27:21, pages 7605.
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In vitro metabolism of mifepristone (RU-486) in rat, monkey and human hepatic S9 fractions: identification of three new mifepristone metabolites

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In vitro metabolism of mifepristone (RU-486) in rat, monkey and human hepatic S9 fractions: identification of three new mifepristone metabolites

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