Xenobiotica, Volume 29, Issue 11 (1999)

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Xenobiotica, Volume 29, Issue 11 (1999)

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Research Article

Article
Correlation of the intrinsic clearance of donepezil (Aricept®) between in vivo and in vitro studies in rat, dog and human
K. Matsui, S. Taniguchi & T. Yoshimura
Pages: 1059-1072
Published online: 22 Sep 2008
AbstractforCorrelation of the intrinsic clearance of donepezil (Aricept®) between in vivo and in vitro studies in rat, dog and human | References | PDF (229.3 KB)
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Article
Isolation and identification of major metabolites of rifalazil in mouse and human
T. Mae, E. Konishi, K. Hosoe & T. Hidaka
Pages: 1073-1087
Published online: 22 Sep 2008
AbstractforIsolation and identification of major metabolites of rifalazil in mouse and human | References | PDF (260.4 KB)
  • 36 Views
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Article
In vitro metabolism of mifepristone (RU-486) in rat, monkey and human hepatic S9 fractions: identification of three new mifepristone metabolites
W. N. Wu, L. A. McKown, M. D. Moyer, T. B. Johannsen & A. R. Takacs
Pages: 1089-1100
Published online: 22 Sep 2008
AbstractforIn vitro metabolism of mifepristone (RU-486) in rat, monkey and human hepatic S9 fractions: identification of three new mifepristone metabolites | References | PDF (392 KB)
  • 106 Views
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Article
Metabolism of ethyl methyl sulphide and sulphoxide in rat microsomal fractions
I. P. Nnane & L. A. Damani
Pages: 1101-1113
Published online: 22 Sep 2008
AbstractforMetabolism of ethyl methyl sulphide and sulphoxide in rat microsomal fractions | References | PDF (218.6 KB)
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Article
Rat cytochromes P450 (CYP) specifically contribute to the reductive bioactivation of AQ4N, an alkylaminoanthraquinone-di-N-oxide anticancer prodrug
S. M. Raleigh, E. Wanogho, M. D. Burke & L. H. Patterson
Pages: 1115-1122
Published online: 22 Sep 2008
AbstractforRat cytochromes P450 (CYP) specifically contribute to the reductive bioactivation of AQ4N, an alkylaminoanthraquinone-di-N-oxide anticancer prodrug | References | PDF (166.7 KB)
  • 60 Views
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Article
Metabolism of CP-195,543, a leukotriene B4 receptor antagonist, in the Long-Evans rat and Cynomolgus monkey
D. K. Dalvie & J. P. O'Donnell
Pages: 1123-1140
Published online: 22 Sep 2008
AbstractforMetabolism of CP-195,543, a leukotriene B4 receptor antagonist, in the Long-Evans rat and Cynomolgus monkey | References | PDF (283.8 KB)
  • 40 Views
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Article
Role of sialylation in determining the pharmacokinetics of neutrophil inhibitory factor (NIF) in the Fischer 344 rat
R. Webster, J. Taberner, A. Edgington, S. Guhan, J. Varghese, H. Feeney, L. Blocker & S. G. Jezequel
Pages: 1141-1155
Published online: 22 Sep 2008
AbstractforRole of sialylation in determining the pharmacokinetics of neutrophil inhibitory factor (NIF) in the Fischer 344 rat | References | PDF (221.3 KB)
  • 62 Views
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Article
Metabolism of furazolidone: alternative pathways and modes of toxicity in different cell lines
I. De Angelis, L. Rossi, J. Z. Pedersen, A. L. Vignoli, O. Vincentini, L. A. P. Hoogenboom, T. H. G. Polman, A. Stammati & F. Zucco
Pages: 1157-1169
Published online: 22 Sep 2008
AbstractforMetabolism of furazolidone: alternative pathways and modes of toxicity in different cell lines | References | PDF (247.1 KB)
  • 62 Views
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Article
Association of cytochrome P450 induction with oxidative stress in vivo as evidenced by 3-hydroxylation of salicylate
M. Strolin-Benedetti, G. Brogin, M. Bani, F. Oesch & J. G. Hengstler
Pages: 1171-1180
Published online: 22 Sep 2008
AbstractforAssociation of cytochrome P450 induction with oxidative stress in vivo as evidenced by 3-hydroxylation of salicylate | References | PDF (185.1 KB)
  • 83 Views
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Article
'Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data
J. K. Nicholson, J. C. Lindon & E. Holmes
Pages: 1181-1189
Published online: 22 Sep 2008
First Page Previewfor'Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data | References | PDF (177 KB)
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