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Research Article

Medical vs. surgical treatment for clomiphene citrate-resistant women with polycystic ovary syndrome

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Pages 289-293 | Published online: 02 Jul 2009

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Read on this site (4)

Martina Sunj, Miro Kasum, Tomislav Canic, Deni Karelovic, Marijan Tandara, Leida Tandara & Ivan Palada. (2014) Assessment of ovarian reserve after unilateral diathermy with thermal doses adjusted to ovarian volume. Gynecological Endocrinology 30:11, pages 785-788.
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Cai-Hong Ma, Shuo Yang, Jie Qiao, Yan Yang & Ping Liu. (2010) Evaluation of the tissue damage of porcine ovaries after bipolar drilling under transvaginal hydrolaparoscopy – an in vitro experiment. Gynecological Endocrinology 26:7, pages 549-553.
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Francesca Cristello, Vito Cela, Paolo GIovanni Artini & Andrea Riccardo Genazzani. (2005) Therapeutic strategies for ovulation induction in infertile women with polycystic ovary syndrome. Gynecological Endocrinology 21:6, pages 340-352.
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Articles from other publishers (45)

Ming-Li Sun, Wen-Pei Bai, Qing-Kun Song, Hui-Ying Wang, Guo-Lan Gao, Liang Zheng & Xing-He Wang. (2022) Metformin With or Without Clomiphene Citrate Versus Laparoscopic Ovarian Drilling With or Without Clomiphene Citrate to Treat Patients With Clomiphene Citrate-Resistant Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis. Frontiers in Pharmacology 13.
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Dalal Kojok, Ghina Ghazeeri & Johnny T. Awwad. 2022. Polycystic Ovary Syndrome. Polycystic Ovary Syndrome 233 253 .
Lifang Yuan, Hongbo Wu, Weiyu Huang, Yin Bi, Aiping Qin & Yihua Yang. (2021) The function of metformin in endometrial receptivity (ER) of patients with polycyclic ovary syndrome (PCOS): a systematic review and meta-analysis. Reproductive Biology and Endocrinology 19:1.
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Yuqi Liu, Juan Li, Zhe Yan, Dan Liu, Jinfang Ma & Nanwei Tong. (2021) Improvement of Insulin Sensitivity Increases Pregnancy Rate in Infertile PCOS Women: A Systemic Review. Frontiers in Endocrinology 12.
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Yi-Fei Sun, Jie Zhang, Yue-Ming Xu, Zi-Yu Cao, Yi-Zhuo Wang, Gui-Min Hao & Bu-Lang Gao. (2020) High BMI and Insulin Resistance Are Risk Factors for Spontaneous Abortion in Patients With Polycystic Ovary Syndrome Undergoing Assisted Reproductive Treatment: A Systematic Review and Meta-Analysis. Frontiers in Endocrinology 11.
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Esmée M Bordewijk, Ka Ying Bonnie Ng, Lidija Rakic, Ben Willem J Mol, Julie Brown, Tineke J Crawford & Madelon van Wely. (2020) Laparoscopic ovarian drilling for ovulation induction in women with anovulatory polycystic ovary syndrome. Cochrane Database of Systematic Reviews.
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Abigail Sharpe, Lara C Morley, Thomas Tang, Robert J Norman & Adam H Balen. (2019) Metformin for ovulation induction (excluding gonadotrophins) in women with polycystic ovary syndrome. Cochrane Database of Systematic Reviews 2019:12.
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Sam Lepine, Junyoung Jo, Mostafa Metwally & Ying C Cheong. (2017) Ovarian surgery for symptom relief in women with polycystic ovary syndrome. Cochrane Database of Systematic Reviews 2017:11.
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Alan Penzias, Kristin Bendikson, Samantha Butts, Christos Coutifaris, Tommaso Falcone, Gregory Fossum, Susan Gitlin, Clarisa Gracia, Karl Hansen, Andrew La Barbera, Jennifer Mersereau, Randall Odem, Richard Paulson, Samantha Pfeifer, Margareta Pisarska, Robert Rebar, Richard Reindollar, Mitchell Rosen, Jay Sandlow & Michael Vernon. (2017) Role of metformin for ovulation induction in infertile patients with polycystic ovary syndrome (PCOS): a guideline. Fertility and Sterility 108:3, pages 426-441.
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Hatem Abu Hashim, Osama Foda & Essam Ghayaty. (2015) Combined metformin‐clomiphene in clomiphene‐resistant polycystic ovary syndrome: a systematic review and meta‐analysis of randomized controlled trials. Acta Obstetricia et Gynecologica Scandinavica 94:9, pages 921-930.
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Xiao-Hong Wang, Jun-Qing Wang, Yan Xu & Li-Ping Huang. (2014) Therapeutic effects of metformin and laparoscopic ovarian drilling in treatment of clomiphene and insulin-resistant polycystic ovary syndrome. Archives of Gynecology and Obstetrics 291:5, pages 1089-1094.
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Johnny T. Awwad & Ghina Ghazeeri. 2014. Polycystic Ovary Syndrome. Polycystic Ovary Syndrome 165 180 .
Hossam O. Hamed. (2013) Role of adiponectin and its receptor in prediction of reproductive outcome of metformin treatment in patients with polycystic ovarian syndrome. Journal of Obstetrics and Gynaecology Research 39:12, pages 1596-1603.
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Ibrahim Abd Elgafor el sharkwy. (2013) Metformin versus laparoscopic unilateral ovarian drilling in clomiphene resistant women with polycystic ovary syndrome. Middle East Fertility Society Journal 18:3, pages 202-207.
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Hatem Abu Hashim, Hesham Al-Inany, Michel De Vos & Herman Tournaye. (2013) Three decades after Gjönnaess’s laparoscopic ovarian drilling for treatment of PCOS; what do we know? An evidence-based approach. Archives of Gynecology and Obstetrics 288:2, pages 409-422.
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J.-L. Pouly, M. Krief, B. Rabischong, F. Brugnon, A.-S. Gremeau, L. Dejou, N. Fabre, G. Mage, M. Canis & X. Folini.. (2013) Drilling ovarien par fertiloscopie : faisabilité, résultats et valeurs prédictives. Gynécologie Obstétrique & Fertilité 41:4, pages 235-241.
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Cindy Farquhar, Julie Brown & Jane Marjoribanks. (2012) Laparoscopic drilling by diathermy or laser for ovulation induction in anovulatory polycystic ovary syndrome. Cochrane Database of Systematic Reviews.
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Hervé Fernandez, Michèle Morin-Surruca, Antoine Torre, Erika Faivre, Xavier Deffieux & Amélie Gervaise. (2011) Ovarian drilling for surgical treatment of polycystic ovarian syndrome: a comprehensive review. Reproductive BioMedicine Online 22:6, pages 556-568.
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Hatem Abu Hashim, Naser El Lakany & Lotfy Sherief. (2010) Combined metformin and clomiphene citrate versus laparoscopic ovarian diathermy for ovulation induction in clomiphene‐resistant women with polycystic ovary syndrome: A randomized controlled trial. Journal of Obstetrics and Gynaecology Research 37:3, pages 169-177.
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Christophe Poncelet & Christophe SiferJ.-N. Hugues. 2011. Physiologie, pathologie et thérapie de la reproduction chez l’humain. Physiologie, pathologie et thérapie de la reproduction chez l’humain 183 197 .
K. K. Roy, Jinee Baruah, Aparna Sharma, J. B. Sharma, Sunesh Kumar, Garima Kachava & Debjyoti Karmakar. (2009) A prospective randomized trial comparing the clinical and endocrinological outcome with rosiglitazone versus laparoscopic ovarian drilling in patients with polycystic ovarian disease resistant to ovulation induction with clomiphene citrate. Archives of Gynecology and Obstetrics 281:5, pages 939-944.
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Hossam O. Hamed, Asmaa F. Hasan, Omyma G. Ahmed & Marwa A. Ahmed. (2009) Retracted: Metformin versus laparoscopic ovarian drilling in clomiphene‐ and insulin‐resistant women with polycystic ovary syndrome . International Journal of Gynecology & Obstetrics 108:2, pages 143-147.
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Yun Hee KooYong Jin Na. (2010) The infertility treatment related with polycystic ovary syndrome. Korean Journal of Obstetrics and Gynecology 53:10, pages 869.
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Mark Gibson. 2010. Reproductive Endocrinology and Infertility. Reproductive Endocrinology and Infertility 525 543 .
Mansoor Ashrafinia, Reihaneh Hosseini, Ashraf Moini, Bita Eslami & Zahra Asgari. (2009) Comparison of metformin treatment and laparoscopic ovarian diathermy in patients with polycystic ovary syndrome. International Journal of Gynecology & Obstetrics 107:3, pages 236-239.
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H. Fernandez. (2009) Une alternative pour traiter l’infertilité : le drilling ovarien. Gynécologie Obstétrique & Fertilité 37, pages 17-18.
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Kelsey E. S. Salley & John E. Nestler. 2010. Diabetes in Women. Diabetes in Women 181 205 .
Hakan Yarali, Gurkan Bozdag & Ibrahim Esinler. 2010. Infertility and Assisted Reproduction. Infertility and Assisted Reproduction 294 301 .
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Karen A Cocksedge, Tin-Chiu Li, Sotiris H Saravelos & Mostafa Metwally. (2008) A reappraisal of the role of polycystic ovary syndrome in recurrent miscarriage. Reproductive BioMedicine Online 17:1, pages 151-160.
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Etelka Moll, Fulco van der Veen & Madelon van Wely. (2007) The role of metformin in polycystic ovary syndrome: a systematic review. Human Reproduction Update 13:6, pages 527-537.
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M.L. Hendriks, J.C.F. Ket, P.G.A. Hompes, R. Homburg & C.B. Lambalk. (2007) Why does ovarian surgery in PCOS help? Insight into the endocrine implications of ovarian surgery for ovulation induction in polycystic ovary syndrome. Human Reproduction Update 13:3, pages 249-264.
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Kimberly E. Liu, Ivanna Viola Tataryn & Margaret Sagle. (2006) Use of Metformin for Ovulation Induction in Women Who Have Polycystic Ovary Syndrome With or Without Evidence of Insulin Resistance. Journal of Obstetrics and Gynaecology Canada 28:7, pages 595-599.
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Cihat Unlu & Cem S. Atabekoglu. (2006) Surgical treatment in polycystic ovary syndrome. Current Opinion in Obstetrics & Gynecology 18:3, pages 286-292.
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Stefano Palomba, Francesco OrioJrJr, Angela Falbo, Tiziana Russo, Grande Caterina, Francesco Manguso, Achille Tolino, Annamaria Colao & Fulvio Zullo. (2005) Metformin administration and laparoscopic ovarian drilling improve ovarian response to clomiphene citrate (CC) in oligo‐anovulatory CC‐resistant women with polycystic ovary syndrome. Clinical Endocrinology 63:6, pages 631-635.
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A. Gervaise & H. Fernandez. (2005) Le drilling ovarien dans le traitement des ovaires polykystiques. Gynécologie Obstétrique & Fertilité 33:9, pages 713-717.
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Hakan Kaya, Mekin Sezik & Okan Ozkaya. (2005) Evaluation of a new surgical approach for the treatment of clomiphene citrate-resistant infertility in polycystic ovary syndrome: Laparoscopic ovarian multi-needle intervention. Journal of Minimally Invasive Gynecology 12:4, pages 355-358.
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Thomas Strowitzki & Michael von Wolff. (2005) Laparoscopic ovarian drilling (LOD) in patients with polycystic ovary syndrome (PCOS): an alternative approach to medical treatment?. Gynecological Surgery 2:2, pages 71-79.
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Hasan Y. Malkawi & Hussein S. Qublan. (2005) Laparoscopic ovarian drilling in the treatment of polycystic ovary syndrome: How many punctures per ovary are needed to improve the reproductive outcome?. Journal of Obstetrics and Gynaecology Research 31:2, pages 115-119.
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Ahmed Y. Rizk, Mohamed A. Bedaiwy & Hesham G. Al-Inany. (2005) N-acetyl-cysteine is a novel adjuvant to clomiphene citrate in clomiphene citrate–resistant patients with polycystic ovary syndrome. Fertility and Sterility 83:2, pages 367-370.
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Willem Ombelet, Petra De Sutter, Josiane Van der Elst & Guy Martens. (2005) Multiple gestation and infertility treatment: registration, reflection and reaction—the Belgian project. Human Reproduction Update 11:1, pages 3-14.
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Jonathan Lord & Terry Wilkin. (2004) Metformin in polycystic ovary syndrome. Current Opinion in Obstetrics and Gynecology 16:6, pages 481-486.
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C FARQUHAR. (2004) The role of ovarian surgery in polycystic ovary syndrome. Best Practice & Research Clinical Obstetrics & Gynaecology 18:5, pages 789-802.
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S. Palomba, F. OrioJr.Jr., T. Russo, A. Falbo, T. Cascella, A. Colao, G. Lombardi & F. Zullo. (2014) Is ovulation induction still a therapeutic problem in patients with polycystic ovary syndrome?. Journal of Endocrinological Investigation 27:8, pages 796-805.
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Hussein S. Qublan. (2003) Habitual abortion: causes, diagnosis, and treatment. Reviews in Gynaecological Practice 3:2, pages 75-80.
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