597
Views
57
CrossRef citations to date
0
Altmetric
Review Article

Cinnamon (Cinnamomum zeylanicum) as an antidote or a protective agent against natural or chemical toxicities: a review

ORCID Icon, ORCID Icon & ORCID Icon
Pages 338-351 | Received 03 Oct 2017, Accepted 12 Dec 2017, Published online: 10 Jan 2018

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (4)

Ting Chen, Shengchuan Bao, Juan Chen, Jiaxiang Zhang, Hailiang Wei, Xin Hu, Yan Liang, Jingtao Li & Shuguang Yan. (2023) Xiaojianzhong decoction attenuates aspirin-induced gastric mucosal injury via the PI3K/AKT/mTOR/ULK1 and AMPK/ULK1 pathways. Pharmaceutical Biology 61:1, pages 1234-1248.
Read now
Akanksha Rani, Bhawana Kanyal, Aabha, Geeta Tewari, Chitra Pande & Om Prakash. (2022) Chemodiversity and Antioxidant Potential of the Essential Oil of Fresh Leaves of Cinnamomum zeylanicum Blume from Uttarakhand. Journal of Essential Oil Bearing Plants 25:4, pages 783-795.
Read now
Soraya Mahmoudi, Amir Abbas Farshid, Esmaeal Tamaddonfard, Mehdi Imani & Farahnaz Noroozinia. (2022) Behavioral, histopathological, and biochemical evaluations on the effects of cinnamaldehyde, naloxone, and their combination in morphine-induced cerebellar toxicity. Drug and Chemical Toxicology 45:1, pages 250-261.
Read now
Carla Condò, Immacolata Anacarso, Carla Sabia, Ramona Iseppi, Igor Anfelli, Luca Forti, Simona de Niederhäusern, Moreno Bondi & Patrizia Messi. (2020) Antimicrobial activity of spices essential oils and its effectiveness on mature biofilms of human pathogens. Natural Product Research 34:4, pages 567-574.
Read now

Articles from other publishers (53)

Aleyna Bahçıvan, Meltem Şaylan, Osman Sagdic & Sezgin Bakırdere. (2024) CoSn(OH)6 nanocubes as a solid sorbent for the effective preconcentration of copper ions in cinnamon (Cinnamomum zeylanicum) extract. Food Chemistry 447, pages 139037.
Crossref
Pronay Mandal & S. K. Kanthlal. (2024) Vascular targeting of constituents of commonly used spices and its molecular interactions in endothelial dysfunction: A review. Phytochemistry Reviews.
Crossref
Mohammadabadi Taherah. (2024) Cinnamon: A potent nutraceutical agent for the protection of the cardiovascular syste. Journal of Cardiovascular Medicine and Cardiology 11:1, pages 1-2.
Crossref
Mansi Singh, Shih-Hsiu Lo, Rajni Dubey, Sudhashekhar Kumar, Kundan Kumar Chaubey & Sanjay Kumar. (2023) Plant-Derived Natural Compounds as an Emerging Antiviral in Combating COVID-19. Indian Journal of Microbiology 63:4, pages 429-446.
Crossref
Giovana Feltes, Sandra C. Ballen, Juliana Steffens, Natalia Paroul & Clarice Steffens. (2023) Differentiating True and False Cinnamon: Exploring Multiple Approaches for Discrimination. Micromachines 14:10, pages 1819.
Crossref
Shahnam Shamsabadi, Yazdan Nazer, Javad Ghasemi, Erfan Mahzoon, Vafa Baradaran Rahimi, Basiru O. Ajiboye & Vahid Reza Askari. (2023) Promising influences of zingerone against natural and chemical toxins: A comprehensive and mechanistic review. Toxicon 233, pages 107247.
Crossref
Amritha Manoharan, Jong Min Oh, Feba Benny, Sunil Kumar, Mohamed A. Abdelgawad, Mohammed M. Ghoneim, Mohamed E. Shaker, Mohamed El-Sherbiny, Hailah M. Almohaimeed, Prashant Gahtori, Hoon Kim & Bijo Mathew. (2023) Assembling a Cinnamyl Pharmacophore in the C3-Position of Substituted Isatins via Microwave-Assisted Synthesis: Development of a New Class of Monoamine Oxidase-B Inhibitors for the Treatment of Parkinson’s Disease. Molecules 28:16, pages 6167.
Crossref
Sohail Hussain, Saeed Alshahrani, Rahimullah Siddiqui, Andleeb Khan, Manal Mohammed Elhassan Taha, Rayan A. Ahmed, Abdulmajeed M. Jali, Marwa Qadri, Khairat H. M. Khairat & Mohammad Ashafaq. (2023) Cinnamon Oil Alleviates Acetaminophen-Induced Uterine Toxicity in Rats by Abrogation of Oxidative Stress, Apoptosis, and Inflammation. Plants 12:12, pages 2290.
Crossref
Zeinab Yazdanpanah, Sara Beigrezaei, Sahar Mohseni-Takalloo & Amin Salehi-Abargouei. (2023) Effects of cinnamon supplementation on serum levels of liver enzymes: A systematic review and meta-analysis of randomized controlled clinical trials. Journal of Herbal Medicine 39, pages 100655.
Crossref
Mersedeh Shayan, Soghra Mehri, Bibi Marjan Razavi & Hossein Hosseinzadeh. (2022) Minocycline as a Neuroprotective Agent in Arsenic-Induced Neurotoxicity in PC12 Cells. Biological Trace Element Research 201:6, pages 2955-2962.
Crossref
Mona A. Mohammed. (2023) Fighting cytokine storm and immunomodulatory deficiency: By using natural products therapy up to now. Frontiers in Pharmacology 14.
Crossref
Giannina Vásquez Lizama, Nicolás Ramos Pazos & Roger Yefi Carrasco. (2023) Desinfectantes convencionales y alternativas sobre el desarrollo de cándida albicans. TECHNO REVIEW. International Technology, Science and Society Review /Revista Internacional de Tecnología, Ciencia y Sociedad 13:3, pages 1-12.
Crossref
Mahmoud Abdelghaffar Emam, Sameh Mohamed Farouk, Ahmed Aljazzar, Abeer A. Abdelhameed, Abeer A. Eldeeb & Fatma Abdel-monem Gad. (2023) Curcumin and cinnamon mitigates lead acetate-induced oxidative damage in the spleen of rats. Frontiers in Pharmacology 13.
Crossref
Azar Hosseini, Bibi Marjan Razavi & Hossein Hosseinzadeh. (2023) Protective effects of pomegranate (Punica granatum) and its main components against natural and chemical toxic agents: A comprehensive review. Phytomedicine 109, pages 154581.
Crossref
Sipper Khan, Amna Sahar, Tayyaba Tariq, Aysha Sameen & Farwa Tariq. 2023. Essential Oils. Essential Oils 1 36 .
B. Sumithra, Sanjeeb Kumar Mandal, Bishwambhar Mishra, K. V. S. S. N. Mounika, J. Caleb Joel Raj & C. V. S. Aishwarya. 2023. Bioprospecting of Tropical Medicinal Plants. Bioprospecting of Tropical Medicinal Plants 1327 1345 .
Abeer Mostafa Abdalhamed, Gamil Sayed Gamil Zeedan, Amany Ahmed Arafa, Eman Shafeek Ibrahim, Doaa Sedky & Amani Abdel nabey Hafez. (2022) Detection of Methicillin-Resistant Staphylococcus aureus in Clinical and Subclinical Mastitis in Ruminants and Studying the Effect of Novel Green Synthetized Nanoparticles as One of the Alternative Treatments. Veterinary Medicine International 2022, pages 1-14.
Crossref
Maria Bibiana Zapata Londoño, Diego Fernando Uribe Yunda, Johanny Aguillón Osma & Maria Elena Maldonado‐Celis. 2022. Molecular Mechanisms of Functional Food. Molecular Mechanisms of Functional Food 404 430 .
Li Lu, Yuan Xiong, Juan Zhou, Guangji Wang, Bobin Mi & Guohui Liu. (2022) The Therapeutic Roles of Cinnamaldehyde against Cardiovascular Diseases. Oxidative Medicine and Cellular Longevity 2022, pages 1-23.
Crossref
Gitishree Das, Sandra Gonçalves, J. Basilio Heredia, Anabela Romano, Luis Alfonso Jiménez-Ortega, Erick P. Gutiérrez-Grijalva, Han Seung Shin & Jayanta Kumar Patra. (2022) Cardiovascular protective effect of cinnamon and its major bioactive constituents: An update. Journal of Functional Foods 97, pages 105045.
Crossref
Sidra Bukhari, Muhammad Hamid Siddique, Anum Naeem, InamUllah Khan, Zain Ali, Asiya Essa, Falak Fazal, Riffat Aysha Anis, Lukas Moran, Aneesa Sultan, Iram Murtaza, Petr Vanhara & Mariam Anees. (2022) Combined efficacy of Cinnamomum zeylanicum and doxorubicin against leukemia through regulation of TRAIL and NF-kappa B pathways in rat model. Molecular Biology Reports 49:7, pages 6495-6507.
Crossref
Mariam Nasser Aljaafari, Maryam Abdulraheem Alkhoori, Mohammed Hag-Ali, Wan-Hee Cheng, Swee-Hua-Erin Lim, Jiun-Yan Loh & Kok-Song Lai. (2022) Contribution of Aldehydes and Their Derivatives to Antimicrobial and Immunomodulatory Activities. Molecules 27:11, pages 3589.
Crossref
Nahla El‑Ashmawy, Eman Khedr, Nehal Alfeky & Amera Ibrahim. (2022) Upregulation of GLUT4 and PI3K, and downregulation of GSK3 mediate the anti‑hyperglycemic effects of proanthocyanidins. Medicine International 2:3.
Crossref
Shabnam Imani, Ainaz Alizadeh, Mahnaz Tabibiazar, Hamed Hamishehkar & Leila Roufegarinejad. (2022) Nanoliposomal co-encapsulation of cinnamon extract and zein hydrolysates with synergistic antioxidant activity for nutraceutical applications. Chemical Papers 76:4, pages 2059-2069.
Crossref
Chang Shang, Hongchen Lin, Xuqin Fang, Yuling Wang, Zhilin Jiang, Yi Qu, Mi Xiang, Zihuan Shen, Laiyun Xin, Yingdong Lu, Jialiang Gao & Xiangning Cui. (2021) Beneficial effects of cinnamon and its extracts in the management of cardiovascular diseases and diabetes. Food & Function 12:24, pages 12194-12220.
Crossref
Maryam Yakhchali, Zahra Taghipour, Mehran Mirabzadeh Ardakani, Mahdi Alizadeh Vaghasloo, Mahdi Vazirian & Sima Sadrai. (2021) Cinnamon and its possible impact on COVID-19: The viewpoint of traditional and conventional medicine. Biomedicine & Pharmacotherapy 143, pages 112221.
Crossref
Shukrya H. Alwan & Muna H. Al-Saeed. (2021) Biosynthesized silver nanoparticles (using Cinnamomum zeylanicum bark extract) improve the fertility status of rats with polycystic ovarian syndrome. Biocatalysis and Agricultural Biotechnology 38, pages 102217.
Crossref
Roghayeh Yahyazadeh, Vafa Baradaran Rahimi, Ahmad Yahyazadeh, Seyed Ahmad Mohajeri & Vahid Reza Askari. (2021) Promising effects of gingerol against toxins: A review article. BioFactors 47:6, pages 885-913.
Crossref
Asel Chandula Weerasekera, Kanchana Samarasinghe, Heethaka Krishantha Sameera de Zoysa, Thushara Chathuranga Bamunuarachchige & Viduranga Yashasvi Waisundara. 2021. Antioxidants - Benefits, Sources, Mechanisms of Action. Antioxidants - Benefits, Sources, Mechanisms of Action.
Oyunchimeg Zandraa, Fahanwi Asabuwa Ngwabebhoh, Rahul Patwa, Hau Trung Nguyen, Marjan Motiei, Nabanita Saha, Tomas Saha & Petr Saha. (2021) Development of dual crosslinked mumio-based hydrogel dressing for wound healing application: Physico-chemistry and antimicrobial activity. International Journal of Pharmaceutics 607, pages 120952.
Crossref
N.G.A.S. Sumudu Chandana & Gertrud E. Morlock. (2021) Eight different bioactivity profiles of 40 cinnamons by multi-imaging planar chromatography hyphenated with effect–directed assays and high-resolution mass spectrometry. Food Chemistry 357, pages 129135.
Crossref
Muhammad A. Alsherbiny, Deep J. Bhuyan, Ibrahim Radwan, Dennis Chang & Chun-Guang Li. (2021) Metabolomic Identification of Anticancer Metabolites of Australian Propolis and Proteomic Elucidation of Its Synergistic Mechanisms with Doxorubicin in the MCF7 Cells. International Journal of Molecular Sciences 22:15, pages 7840.
Crossref
Sara T. Elazab, Nahla S. Elshater, Asmaa T. Y. Kishaway & Huda A. EI-Emam. (2021) Cinnamon Extract and Probiotic Supplementation Alleviate Copper-Induced Nephrotoxicity via Modulating Oxidative Stress, Inflammation, and Apoptosis in Broiler Chickens. Animals 11:6, pages 1609.
Crossref
Natalia Błaszczyk, Angelina Rosiak & Joanna Kałużna-Czaplińska. (2021) The Potential Role of Cinnamon in Human Health. Forests 12:5, pages 648.
Crossref
Mehdi Zobeiri, Fatemeh Parvizi, Zahra Shahpiri, Fatemeh Heydarpour, Morteza Pourfarzam, Mohammad Reza Memarzadeh, Roja Rahimi & Mohammad Hosein Farzaei. (2021) Evaluation of the Effectiveness of Cinnamon Oil Soft Capsule in Patients with Functional Dyspepsia: A Randomized Double-Blind Placebo-Controlled Clinical Trial. Evidence-Based Complementary and Alternative Medicine 2021, pages 1-7.
Crossref
Catarina Milho, Jani Silva, Rafaela Guimarães, Isabel C. F. R. Ferreira, Lillian Barros & Maria José Alves. (2021) Antimicrobials from Medicinal Plants: An Emergent Strategy to Control Oral Biofilms. Applied Sciences 11:9, pages 4020.
Crossref
Tingting Wen, Lei Song & Shucheng Hua. (2021) Perspectives and controversies regarding the use of natural products for the treatment of lung cancer. Cancer Medicine 10:7, pages 2396-2422.
Crossref
Ayesheh Enayati, Thomas P. Johnston & Amirhossein Sahebkar. (2021) Anti-atherosclerotic Effects of Spice-Derived Phytochemicals. Current Medicinal Chemistry 28:6, pages 1197-1223.
Crossref
Gehad E. Elshopakey & Sara T. Elazab. (2021) Cinnamon Aqueous Extract Attenuates Diclofenac Sodium and Oxytetracycline Mediated Hepato-Renal Toxicity and Modulates Oxidative Stress, Cell Apoptosis, and Inflammation in Male Albino Rats. Veterinary Sciences 8:1, pages 9.
Crossref
John I. Ihedioha, Davinson C. Anyogu & Martin E. Ogbonna. (2020) The Effects of Silymarin on Acetaminophen-Induced Acute Hepatic and Renal Toxicities in Domestic Pigeons (Columba livia). Journal of Avian Medicine and Surgery 34:4.
Crossref
Hüseyin BULUT. (2020) Arpada Tuz Stresine Karşı Zingeronun Koruyucu EtkisiThe Protective Effect of Zingeron Against Salt Stress in Barley. Iğdır Üniversitesi Fen Bilimleri Enstitüsü Dergisi 10:4, pages 2932-2942.
Crossref
Roman Lysiuk, Petro Oliynyk, Halyna Antonyak & Dmytro Voronenko. 2020. Poisonous Plants and Phytochemicals in Drug Discovery. Poisonous Plants and Phytochemicals in Drug Discovery 249 268 .
Changyou Zhu, Hongmei Yan, Yin Zheng, Heitor O. Santos, Melahat Sedanur Macit & Ketong Zhao. (2020) Impact of Cinnamon Supplementation on cardiometabolic Biomarkers of Inflammation and Oxidative Stress: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Complementary Therapies in Medicine 53, pages 102517.
Crossref
Papiya Datta, Soumosish PaulDr.Dr., Gobinda Chandra Sadhukhan(Dr.)(Dr.), Nimai Chandra Saha(Dr.)(Dr.) & Soumendranath ChatterjeeDr.Dr.. (2020) AMERLIORATIVE EFFECT OF CINNAMALDEHYDE AGAINST LEAD ACETATE INDUCED SPLENIC TOXICITY OF SWISS ALBINO MICE (MUS MUSCULUS). GLOBAL JOURNAL FOR RESEARCH ANALYSIS, pages 61-63.
Crossref
Mahyar Dorrigiv, Armin Zareiyan & Hossein Hosseinzadeh. (2020) Garlic ( Allium sativum ) as an antidote or a protective agent against natural or chemical toxicities: A comprehensive update review . Phytotherapy Research 34:8, pages 1770-1797.
Crossref
Julia Fabbri, Marina Alejandra Maggiore, Patricia Eugenia Pensel, Guillermo María Denegri & María Celina Elissondo. (2020) In vitro efficacy study of Cinnamomum zeylanicum essential oil and cinnamaldehyde against the larval stage of Echinococcus granulosus. Experimental Parasitology 214, pages 107904.
Crossref
Robert Ose, Jessica Tu, Anne Schink, Joachim Maxeiner, Petra Schuster, Kurt Lucas, Joachim Saloga & Iris Bellinghausen. (2019) Cinnamon extract inhibits allergen‐specific immune responses in human and murine allergy models. Clinical & Experimental Allergy 50:1, pages 41-50.
Crossref
Su Qu, Kunlong Yang, Lei Chen, Man Liu, Qingru Geng, Xiaona He, Yongxin Li, Yongguo Liu & Jun Tian. (2019) Cinnamaldehyde, a Promising Natural Preservative Against Aspergillus flavus. Frontiers in Microbiology 10.
Crossref
Seyedeh Farzaneh Omidkhoda, BiBi Marjan Razavi & Hossein Hosseinzadeh. (2019) Protective effects of Ginkgo biloba L. against natural toxins, chemical toxicities, and radiation: A comprehensive review . Phytotherapy Research 33:11, pages 2821-2840.
Crossref
Gerald Wölkart, Alexander Kollau, Heike Stessel, Michael Russwurm, Doris Koesling, Astrid Schrammel, Kurt Schmidt & Bernd Mayer. (2019) Effects of flavoring compounds used in electronic cigarette refill liquids on endothelial and vascular function. PLOS ONE 14:9, pages e0222152.
Crossref
Muhammad A. Alsherbiny, Wessam H. Abd-Elsalam, Shymaa A. El badawy, Ehab Taher, Mohamed Fares, Allan Torres, Dennis Chang & Chun Guang Li. (2019) Ameliorative and protective effects of ginger and its main constituents against natural, chemical and radiation-induced toxicities: A comprehensive review. Food and Chemical Toxicology 123, pages 72-97.
Crossref
Ahmed Abdeen, Afaf Abdelkader, Mohamed Abdo, Gamal Wareth, Mohamed Aboubakr, Lotfi Aleya & Mohamed Abdel-Daim. (2018) Protective effect of cinnamon against acetaminophen-mediated cellular damage and apoptosis in renal tissue. Environmental Science and Pollution Research 26:1, pages 240-249.
Crossref
Bruna Pereira Lopes, Thaiane Gadioli Gaique, Luana Lopes Souza, Gabriela Silva Monteiro Paula, George E.G. Kluck, Georgia C. Atella, Carmen Cabanelas Pazos-Moura & Karen Jesus Oliveira. (2018) Beneficial effects of Cinnamon on hepatic lipid metabolism are impaired in hypothyroid rats. Journal of Functional Foods 50, pages 210-215.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.