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Original Articles

Validation and use of the CALUX‐bioassay for the determination of dioxins and PCBs in bovine milk

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Pages 863-875 | Accepted 22 Jun 1998, Published online: 10 Jan 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (11)

Felicia Akuamoa, Ron L. A. P. Hoogenboom, Yoran Weide, Guido van der Weg, Ivonne M. C. M. Rietjens & Toine F. H. Bovee. (2022) Presence and risks of polycyclic aromatic hydrocarbons, dioxins and dioxin-like PCBs in dietary plant supplements as elucidated by a combined DR CALUX® bioassay and GC-HRMS based approach. Food Additives & Contaminants: Part A 39:9, pages 1576-1590.
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Benoit Schilter, Karin Burnett, Chantra Eskes, Lucie Geurts, Mélanie Jacquet, Christian Kirchnawy, Peter Oldring, Gabriele Pieper, Elisabeth Pinter, Manfred Tacker, Heinz Traussnig, Peter Van Herwijnen & Alan Boobis. (2019) Value and limitation of in vitro bioassays to support the application of the threshold of toxicological concern to prioritise unidentified chemicals in food contact materials. Food Additives & Contaminants: Part A 36:12, pages 1903-1936.
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Paulien Adamse, Stefanie Schoss, Rob M. C. Theelen & Ron L. A. P. Hoogenboom. (2017) Levels of dioxins and dioxin-like PCBs in food of animal origin in the Netherlands during the period 2001–2011. Food Additives & Contaminants: Part A 34:1, pages 78-92.
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Paulien Adamse, H.J. (Ine) Van der Fels-Klerx, Stefanie Schoss, Jacob de Jong & Ron L.A.P. Hoogenboom. (2015) Concentrations of dioxins and dioxin-like PCBs in feed materials in the Netherlands, 2001–11. Food Additives & Contaminants: Part A 32:8, pages 1301-1311.
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Marija Pinne & Judy L Raucy. (2014) Advantages of cell-based high-volume screening assays to assess nuclear receptor activation during drug discovery. Expert Opinion on Drug Discovery 9:6, pages 669-686.
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Eva C. Bonefeld-Jørgensen$suffix/text()$suffix/text() & Manhai Long. (2010) Dioxin-like activity in the blood of Greenlandic Inuit and Danish women: a pilot study. International Journal of Circumpolar Health 69:2, pages 181-194.
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W.J. De Waard, J.M.M.J.G. Aarts, A.C.M. Peijnenburg, T.M.C.M. De Kok, F.-J. Van Schooten & L.A.P. Hoogenboom. (2008) Ah receptor agonist activity in frequently consumed food items. Food Additives & Contaminants: Part A 25:6, pages 779-787.
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L. A. P. Hoogenboom, C. A. Kan, M. J. Zeilmaker, J. Van Eijkeren & W. A. Traag. (2006) Carry-over of dioxins and PCBs from feed and soil to eggs at low contamination levels – influence of mycotoxin binders on the carry-over from feed to eggs. Food Additives & Contaminants 23:5, pages 518-527.
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G Gizzi, L. A. P Hoogenboom, C Von Holst, M Rose & E Anklam. (2005) Determination of dioxins (PCDDs/PCDFs) and PCBs in food and feed using the DR CALUX® bioassay: Results of an international validation study. Food Additives & Contaminants 22:5, pages 472-481.
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P. Laier, T. Cederberg, J. C. Larsen & A. M. Vinggaard. (2003) Applicability of the CALUX bioassay for screening of dioxin levels in human milk samples. Food Additives & Contaminants 20:6, pages 583-595.
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Larry L. Needham, John J. Ryan & Peter Fürst. (2002) GUIDELINES FOR ANALYSIS OF HUMAN MILK FOR ENVIRONMENTAL CHEMICALS. Journal of Toxicology and Environmental Health, Part A 65:22, pages 1893-1908.
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Yao Zhou, Stefan P.J. van Leeuwen, Marco Knobloch, Caroline Dirks, Yoran Weide & Toine F.H. Bovee. (2021) Impurities in technical mixtures of chlorinated paraffins show AhR agonist properties as determined by the DR-CALUX bioassay. Toxicology in Vitro 72, pages 105098.
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Hiroyuki Kojima, Shinji Takeuchi, Mitsuru Iida, Shoji F. Nakayama & Takuya Shiozaki. (2015) A sensitive, rapid, and simple DR-EcoScreen bioassay for the determination of PCDD/Fs and dioxin-like PCBs in environmental and food samples. Environmental Science and Pollution Research 25:8, pages 7101-7112.
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Go Suzuki, Masafumi Nakamura, Chieko Michinaka, Nguyen Minh Tue, Hiroshi Handa & Hidetaka Takigami. (2017) Separate screening of brominated and chlorinated dioxins in field samples using in vitro reporter gene assays with rat and mouse hepatoma cell lines. Analytica Chimica Acta 975, pages 86-95.
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