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Acta Oncologica Volume 46, 2007 - Issue 8
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ORIGINAL ARTICLE

LRIG1 expression in colorectal cancer

Ingrid Ljuslinder Department of Radiation Sciences, Oncology, Umeå University, Umeå, SwedenCorrespondence[email protected]
,
Irina Golovleva Department of Medical Biosciences, Medical and Clinical Genetics, Umeå, Sweden
,
Richard Palmqvist Department of Medical Biosciences and Pathology, Umeå, Sweden
,
Åke Öberg Department of Surgical and Perioperative Sciences, Division of Surgery, Umeå University, Sweden
,
Roger Stenling Department of Medical Biosciences and Pathology, Umeå, Sweden
,
Yvonne Jonsson Department of Radiation Sciences, Oncology, Umeå University, Umeå, Sweden
,
Håkan Hedman Department of Radiation Sciences, Oncology, Umeå University, Umeå, Sweden
,
Roger Henriksson Department of Radiation Sciences, Oncology, Umeå University, Umeå, Sweden; Astra Zeneca, Sweden
&
Beatrice Malmer Department of Radiation Sciences, Oncology, Umeå University, Umeå, Sweden
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Pages 1118-1122 | Received 07 Mar 2007, Published online: 08 Jul 2009

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David Lindquist, Samuel Kvarnbrink, Roger Henriksson & Håkan Hedman. (2014) LRIG and cancer prognosis. Acta Oncologica 53:9, pages 1135-1142.
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Articles from other publishers (25)

Fang Cao, Yunpeng Jiang, Lin Chang, Hongzhen Du, De Chang, Chunxiao Pan, Xiaozheng Huang, Donglin Yu, Mi Zhang, Yongna Fan, Xiaocui Bian & Kailong Li. (2023) High-throughput functional screen identifies YWHAZ as a key regulator of pancreatic cancer metastasis. Cell Death & Disease 14:7.
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Saurav Panicker & Satish Ramalingam. 2023. Cancer Genes. Cancer Genes 52 70 .
Yibing Ji, Rahul Kumar, Abhiram Gokhale, Hseu-Ping Chao, Kiera Rycaj, Xin Chen, Qiuhui Li & Dean G. Tang. (2022) LRIG1, a regulator of stem cell quiescence and a pleiotropic feedback tumor suppressor. Seminars in Cancer Biology 82, pages 120-133.
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Shirin Salehizadeh, Mandana Hasanzad, Azade Amini Kadijani & Abolfazl Akbari. (2019) The Expression Analysis of Intestinal Cancer Stem Cell Marker Lgr5 in Colorectal Cancer Patients and the Correlation with Histopathological Markers. Journal of Gastrointestinal Cancer 51:2, pages 591-599.
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Qiuhui Li, Bigang Liu, Hsueh-Ping Chao, Yibing Ji, Yue Lu, Rashid Mehmood, Collene Jeter, Taiping Chen, John R. Moore, Wenqian Li, Can Liu, Kiera Rycaj, Amanda Tracz, Jason Kirk, Tammy Calhoun-Davis, Jie Xiong, Qu Deng, Jiaoti Huang, Barbara A. Foster, Abhiram Gokhale, Xin Chen & Dean G. Tang. (2019) LRIG1 is a pleiotropic androgen receptor-regulated feedback tumor suppressor in prostate cancer. Nature Communications 10:1.
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Sungsook Yu, Mijeong Yang, Kyung-Min Lim, Yejin Cho, Hyunji Kim, Keunwook Lee, Sang-Ho Jeong, Robert J. Coffey, James R. Goldenring & Ki Taek Nam. (2018) Expression of LRIG1, a Negative Regulator of EGFR, Is Dynamically Altered during Different Stages of Gastric Carcinogenesis. The American Journal of Pathology 188:12, pages 2912-2923.
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Dustin Flanagan, Chloe Austin, Elizabeth Vincan & Toby Phesse. (2018) Wnt Signalling in Gastrointestinal Epithelial Stem Cells. Genes 9:4, pages 178.
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Xiaofang Jiang & Huiwu Li. (2016) Overexpression of LRIG1 regulates PTEN via MAPK/MEK signaling pathway in esophageal squamous cell carcinoma. Experimental and Therapeutic Medicine 12:4, pages 2045-2052.
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Yibin Xu, Priscilla Soo, Francesca Walker, Hui Hua Zhang, Nicholas Redpath, Chin Wee Tan, Nicos A. Nicola, Timothy E. Adams, Thomas P. Garrett, Jian-Guo Zhang & Antony W. Burgess. (2015) LRIG1 Extracellular Domain: Structure and Function Analysis. Journal of Molecular Biology 427:10, pages 1934-1948.
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Peng Tian, ChaoMing Peng & Lei Zhang. (2015) Biodegradable polymeric gene delivering nanoscale hybrid micelles enhance the suppression effect of LRIG1 in breast cancer. RSC Advances 5:43, pages 34226-34236.
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Tony YuenAgnes StachnikJameel IqbalMiriam SgobbaYogesh GuptaPing LuGraziana ColaianniYaoting Ji, Ling-Ling Zhu, Se-Min KimJianhua LiPeng LiuSudeh IzadmehrJaya SangodkarJack BaileyYathin LatifShiraz MujtabaSolomon EpsteinTerry F. DaviesZhuan Bian, Alberta ZalloneAneel K. AggarwalShozeb HaiderMaria I. NewLi SunGoutham Narla & Mone Zaidi. (2014) Bisphosphonates inactivate human EGFRs to exert antitumor actions. Proceedings of the National Academy of Sciences 111:50, pages 17989-17994.
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Wolfgang J. Köstler & Yosef Yarden. 2015. Molecular Oncology. Molecular Oncology 85 109 .
Lei Chang, Runlin Shi, Tao Yang, Fan Li, Guohao Li, Yonglian Guo, Bin Lang, Weimin Yang, Qianyuan Zhuang & Hua Xu. (2013) Restoration of LRIG1 suppresses bladder cancer cell growth by directly targeting EGFR activity. Journal of Experimental & Clinical Cancer Research 32:1.
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Xu-chen Qi, Da-jiang Xie, Qing-feng Yan, Yi-rong Wang, Yin-xin Zhu, Cong Qian & Shu-xu Yang. (2013) LRIG1 dictates the chemo-sensitivity of temozolomide (TMZ) in U251 glioblastoma cells via down-regulation of EGFR/topoisomerase-2/Bcl-2. Biochemical and Biophysical Research Communications 437:4, pages 565-572.
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Hanine Rafidi, Francisco MercadoIIIIII, Michael Astudillo, William H.D. Fry, Matthew Saldana, Kermit L. CarrawayIIIIII & Colleen Sweeney. (2013) Leucine-rich Repeat and Immunoglobulin Domain-containing Protein-1 (Lrig1) Negative Regulatory Action toward ErbB Receptor Tyrosine Kinases Is Opposed by Leucine-rich Repeat and Immunoglobulin Domain-containing Protein 3 (Lrig3). Journal of Biological Chemistry 288:30, pages 21593-21605.
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Xin-yao He, Xian-jin Liu, Xiao Chen, Liu-guan Bian, Wei-guo Zhao, Jian-kang Shen & Qing-fang Sun. (2013) Gambogic acid induces EGFR degradation and Akt/mTORC1 inhibition through AMPK dependent-LRIG1 upregulation in cultured U87 glioma cells. Biochemical and Biophysical Research Communications 435:3, pages 397-402.
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Y Wang, E J Poulin & R J Coffey. (2013) LRIG1 is a triple threat: ERBB negative regulator, intestinal stem cell marker and tumour suppressor. British Journal of Cancer 108:9, pages 1765-1770.
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Zhigang Zhang & Jian Huang. (2013) Intestinal stem cells – types and markers. Cell Biology International 37:5, pages 406-414.
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Lu Zhang, Kakajan Komurov, Woodring E. Wright & Jerry W. Shay. (2012) Identification of novel driver tumor suppressors through functional interrogation of putative passenger mutations in colorectal cancer. International Journal of Cancer 132:3, pages 732-737.
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Anne E. Powell, Yang Wang, Yina Li, Emily J. Poulin, Anna L. Means, Mary K. Washington, James N. Higginbotham, Alwin Juchheim, Nripesh Prasad, Shawn E. Levy, Yan Guo, Yu Shyr, Bruce J. Aronow, Kevin M. Haigis, Jeffrey L. Franklin & Robert J. Coffey. (2012) The Pan-ErbB Negative Regulator Lrig1 Is an Intestinal Stem Cell Marker that Functions as a Tumor Suppressor. Cell 149:1, pages 146-158.
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Sheryl R. Krig, Seth Frietze, Catalina Simion, Jamie K. Miller, Will H.D. Fry, Hanine Rafidi, Lakmal Kotelawala, Lihong Qi, Obi L. Griffith, Joe W. Gray, Kermit L. CarrawayIIIIII & Colleen Sweeney. (2011) Lrig1 Is an Estrogen-Regulated Growth Suppressor and Correlates with Longer Relapse-Free Survival in ERα-Positive Breast Cancer. Molecular Cancer Research 9:10, pages 1406-1417.
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Shannon E. Duke Becker, Rachael Thomas, Vladimir A. Trifonov, Robert K. Wayne, Alexander S. Graphodatsky & Matthew Breen. (2011) Anchoring the dog to its relatives reveals new evolutionary breakpoints across 11 species of the Canidae and provides new clues for the role of B chromosomes. Chromosome Research 19:6, pages 685-708.
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Victoria E. AbrairaTony del RioAndrew F. TuckerJohn SlonimskyHannah L. KeirnesLisa V. Goodrich. (2008) Cross-repressive interactions between Lrig3 and netrin 1 shape the architecture of the inner ear . Development 135:24, pages 4091-4099.
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Silvia Goldoni & Renato V. Iozzo. (2008) Tumor microenvironment: Modulation by decorin and related molecules harboring leucine‐rich tandem motifs. International Journal of Cancer 123:11, pages 2473-2479.
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Jamie K. Miller, David L. Shattuck, Ellen Q. Ingalla, Lily Yen, Alexander D. Borowsky, Lawrence J.T. Young, Robert D. Cardiff, Kermit L. CarrawayIIIIII & Colleen Sweeney. (2008) Suppression of the Negative Regulator LRIG1 Contributes to ErbB2 Overexpression in Breast Cancer. Cancer Research 68:20, pages 8286-8294.
Crossref

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