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Review Article

Cardiotoxicity induced by tyrosine kinase inhibitors

, &
Pages 964-970 | Received 03 Feb 2009, Published online: 08 Oct 2009

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Daryl Sudasena, Dinu Valentin Balanescu, Teodora Donisan, Saamir Hassan, Nicolas Palaskas, Peter Kim, Kaveh Karimzad, Juan Lopez-Mattei, Salman Arain, K. Lance Gould & Cezar Iliescu. (2018) Fulminant Vascular and Cardiac Toxicity Associated with Tyrosine Kinase Inhibitor Sorafenib. Cardiovascular Toxicology 19:4, pages 382-387.
Crossref
Huan Wang, Robert P. Sheehan, Adam C. Palmer, Robert A. Everley, Sarah A. Boswell, Noga Ron-Harel, Alison E. Ringel, Kristina M. Holton, Connor A. Jacobson, Alison R. Erickson, Laura Maliszewski, Marcia C. Haigis & Peter K. Sorger. (2019) Adaptation of Human iPSC-Derived Cardiomyocytes to Tyrosine Kinase Inhibitors Reduces Acute Cardiotoxicity via Metabolic Reprogramming. Cell Systems 8:5, pages 412-426.e7.
Crossref
Jasmin D. Haslbauer, Sarah Lindner, Gesine Bug, Eike Nagel & Valentina O. Puntmann. (2019) Cardiac MRI: a Promising Diagnostic Tool to Detect Cancer Therapeutics–Related Cardiac Dysfunction. Current Cardiovascular Imaging Reports 12:5.
Crossref
Preetesh Jain, Hagop KantarjianPrajwal C. BodduGraciela M. Nogueras-González, Srdan VerstovsekGuillermo Garcia-ManeroGautam BorthakurKoji SasakiTapan M. KadiaPrincy SamHycienth AhanekuSusan O’Brien, Zeev EstrovFarhad RavandiElias JabbourJorge E. Cortes. (2019) Analysis of cardiovascular and arteriothrombotic adverse events in chronic-phase CML patients after frontline TKIs. Blood Advances 3:6, pages 851-861.
Crossref
Maria E. Cabanillas & Shunji Takahashi. (2019) Managing the adverse events associated with lenvatinib therapy in radioiodine-refractory differentiated thyroid cancer. Seminars in Oncology 46:1, pages 57-64.
Crossref
Kerstin Hiesinger, Karen M. Wagner, Bruce D. Hammock, Ewgenij Proschak & Sung Hee Hwang. (2019) Development of multitarget agents possessing soluble epoxide hydrolase inhibitory activity. Prostaglandins & Other Lipid Mediators 140, pages 31-39.
Crossref
Robert RoskoskiJr.Jr.. (2019) Small molecule inhibitors targeting the EGFR/ErbB family of protein-tyrosine kinases in human cancers. Pharmacological Research 139, pages 395-411.
Crossref
Khushwant S. Bhullar, Naiara Orrego Lagarón, Eileen M. McGowan, Indu Parmar, Amitabh Jha, Basil P. Hubbard & H. P. Vasantha Rupasinghe. (2018) Kinase-targeted cancer therapies: progress, challenges and future directions. Molecular Cancer 17:1.
Crossref
Kim A. Henderson, R. Brandon Borders, John B. Ross, Amir Abdulalil, Seth Gibbs, Anthony J. Skowronek, Katherine Knostman, Jay Bailey, Jeremy Smith, Tom Vinci, Brandon Wood, Michael V. Knopp & Brian M. Roche. (2018) Integration of cardiac energetics, function and histology from isolated rat hearts perfused with doxorubicin and doxorubicin-ol; a model for use in drug safety evaluations. Journal of Pharmacological and Toxicological Methods 94, pages 54-63.
Crossref
Md. Jawaid Akhtar, Ahsan Ahmed Khan, Zulphikar Ali, Rikeshwer Prasad Dewangan, Md. Rafi, Md. Quamrul Hassan, Md. Sayeed Akhtar, Anees Ahmad Siddiqui, Sangh Partap, Santosh Pasha & M. Shahar Yar. (2018) Synthesis of stable benzimidazole derivatives bearing pyrazole as anticancer and EGFR receptor inhibitors. Bioorganic Chemistry 78, pages 158-169.
Crossref
Traian Constantin Panciu, Bianca Masgras, Catrinel Ciuca, Raluca Ciomag, Anca Mihăilescu & Adriana Gurghean. (2018) Acute Coronary Syndrome Following Long-Term Erlotinib Treatment. Internal Medicine 15:3, pages 61-66.
Crossref
Hani M Babiker, Ali McBride, Michael Newton, Leigh M. Boehmer, Adrienne Goeller Drucker, Mollie Gowan, Manouchkathe Cassagnol, Todd D. Camenisch, Faiz Anwer & James M. Hollands. (2018) Cardiotoxic effects of chemotherapy: A review of both cytotoxic and molecular targeted oncology therapies and their effect on the cardiovascular system. Critical Reviews in Oncology/Hematology 126, pages 186-200.
Crossref
Baichun Yang & Thomas Papoian. (2018) Preclinical approaches to assess potential kinase inhibitor‐induced cardiac toxicity: Past, present and future. Journal of Applied Toxicology 38:6, pages 790-800.
Crossref
Josephine T. Tauer, Bernadette A. S. Jäger, Anna Ulmer, Paula Geidel, Vera Girke, Lysann Kroschwald & Meinolf Suttorp. 2018. Experimental Animal Models of Human Diseases - An Effective Therapeutic Strategy. Experimental Animal Models of Human Diseases - An Effective Therapeutic Strategy.
Hyang-Ae Lee, Sung-Ae Hyun, Byungjin Byun, Jong-Hak Chae & Ki-Suk Kim. (2018) Electrophysiological mechanisms of vandetanib-induced cardiotoxicity: Comparison of action potentials in rabbit Purkinje fibers and pluripotent stem cell-derived cardiomyocytes. PLOS ONE 13:4, pages e0195577.
Crossref
Devawati Dutta, Ranjita Das, Chhabinath Mandal & Chitra Mandal. (2017) Structure-Based Kinase Profiling To Understand the Polypharmacological Behavior of Therapeutic Molecules. Journal of Chemical Information and Modeling 58:1, pages 68-89.
Crossref
I.L. Davydkin, Kseniya Viktorovna Naumova, A.M. Osadchuk, I.A. Zolotovskaya, O.E. Danilova, T.Yu. Stepanova, O.V. Tereshina, L.V. Limareva, A.S. Shpigel' & T.P. Kuz'mina. (2018) Cardiovascular Toxicity of Tyrosine Kinase Inhibitors in Patients with Chronic Myeloid Leukemia. Clinical oncohematology 11:4, pages 378-387.
Crossref
Leah J. Wilson, Adam Linley, Dean E. Hammond, Fiona E. Hood, Judy M. Coulson, David J. MacEwan, Sarah J. Ross, Joseph R. Slupsky, Paul D. Smith, Patrick A. Eyers & Ian A. Prior. (2018) New Perspectives, Opportunities, and Challenges in Exploring the Human Protein Kinome. Cancer Research 78:1, pages 15-29.
Crossref
Marjan Boerma. 2018. Gender Differences in the Pathogenesis and Management of Heart Disease. Gender Differences in the Pathogenesis and Management of Heart Disease 303 316 .
Catrin Hasselgren & Glenn J. Myatt. 2018. Computational Toxicology. Computational Toxicology 233 244 .
Ping‐Pin Zheng, Jin Li & Johan M Kros. (2017) Breakthroughs in modern cancer therapy and elusive cardiotoxicity: Critical research‐practice gaps, challenges, and insights. Medicinal Research Reviews 38:1, pages 325-376.
Crossref
S. R. Priya, Chandra Shekhar Dravid, Raghunadharao Digumarti & Mitali Dandekar. (2017) Targeted Therapy for Medullary Thyroid Cancer: A Review. Frontiers in Oncology 7.
Crossref
Genevieve Conant, Samad Ahadian, Yimu Zhao & Milica Radisic. (2017) Kinase inhibitor screening using artificial neural networks and engineered cardiac biowires. Scientific Reports 7:1.
Crossref
Sarah D. Lamore, Ernst Ahlberg, Scott Boyer, Michelle L. Lamb, Maria P. Hortigon-Vinagre, Victor Rodriguez, Godfrey L. Smith, Johanna Sagemark, Lars Carlsson, Stephanie M. Bates, Allison L. Choy, Jonna Stålring, Clay W. Scott & Matthew F. Peters. (2017) Deconvoluting Kinase Inhibitor Induced Cardiotoxicity. Toxicological Sciences 158:1, pages 213-226.
Crossref
Genevieve Conant, Benjamin Fook Lun Lai, Rick Xing Ze Lu, Anastasia Korolj, Erika Yan Wang & Milica Radisic. (2017) High-Content Assessment of Cardiac Function Using Heart-on-a-Chip Devices as Drug Screening Model. Stem Cell Reviews and Reports 13:3, pages 335-346.
Crossref
Wan ZhuFanxia ShenLei MaoLei ZhanShuai KangZhengda SunJeffrey NelsonRui ZhangDingquan ZouCameron M. McDougallMichael T. LawtonThiennu H. VuZhijian WuAbraham ScariaPeter ColosiJohn ForsayethHua Su. (2017) Soluble FLT1 Gene Therapy Alleviates Brain Arteriovenous Malformation Severity. Stroke 48:5, pages 1420-1423.
Crossref
Ying Liu, Donna M. Conlon, Xin Bi, Katherine J. Slovik, Jianting Shi, Hailey I. Edelstein, John S. Millar, Ali Javaheri, Marina Cuchel, Evanthia E. Pashos, Jahangir Iqbal, M. Mahmood Hussain, Robert A. Hegele, Wenli Yang, Stephen A. Duncan, Daniel J. Rader & Edward E. Morrisey. (2017) Lack of MTTP Activity in Pluripotent Stem Cell-Derived Hepatocytes and Cardiomyocytes Abolishes apoB Secretion and Increases Cell Stress. Cell Reports 19:7, pages 1456-1466.
Crossref
Ivo Darko Gabrić. (2017) Cardiotoxicity due to biological cancer therapy. Cardiologia Croatica 12:1-2, pages 16-22.
Crossref
Md Jawaid Akhtar, Anees Ahmad Siddiqui, Ahsan Ahmed Khan, Zulphikar Ali, Rikeshwer Prasad Dewangan, Santosh Pasha & M. Shahar Yar. (2017) Design, synthesis, docking and QSAR study of substituted benzimidazole linked oxadiazole as cytotoxic agents, EGFR and erbB2 receptor inhibitors. European Journal of Medicinal Chemistry 126, pages 853-869.
Crossref
Varun Ahuja, Sanjay Bokan & Sharad Sharma. (2017) Predicting toxicities in humans by nonclinical safety testing: an update with particular reference to anticancer compounds. Drug Discovery Today 22:1, pages 127-132.
Crossref
E. Koch & S. Plassmann. 2017. A Comprehensive Guide to Toxicology in Nonclinical Drug Development. A Comprehensive Guide to Toxicology in Nonclinical Drug Development 7 38 .
A. Lajoie, J. Dunhill & M.A. Hamilton. 2017. Cardio-Oncology. Cardio-Oncology 297 307 .
Barbara Bassani, Antonino Bruno, Nicoletta Macrì, Paola Corradino, Douglas M. Noonan & Adriana Albini. 2017. Manual of Cardio-oncology. Manual of Cardio-oncology 107 122 .
Liz Roquemore, M. Ariel Kauss, Catherine Hather, Nick Thomas & Hirdesh Uppal. 2017. Stem Cell-Derived Models in Toxicology. Stem Cell-Derived Models in Toxicology 247 269 .
D. LEKES, I. SZADVARI, O. KRIZANOVA, K. LOPUSNA, I. REZUCHOVA, M. NOVAKOVA, Z. NOVAKOVA, T. PARAK & P. BABULA. (2016) Nilotinib Induces ER Stress and Cell Death in H9c2 Cells. Physiological Research, pages S505-S514.
Crossref
Tarek Magdy, Brian T. Burmeister & Paul W. Burridge. (2016) Validating the pharmacogenomics of chemotherapy-induced cardiotoxicity: What is missing?. Pharmacology & Therapeutics 168, pages 113-125.
Crossref
Karima Ait-Aissa, Johnathan D. Ebben, Andrew O. Kadlec & Andreas M. Beyer. (2016) Friend or foe? Telomerase as a pharmacological target in cancer and cardiovascular disease. Pharmacological Research 111, pages 422-433.
Crossref
Yi Yang & Peili Bu. (2016) Progress on the cardiotoxicity of sunitinib: Prognostic significance, mechanism and protective therapies. Chemico-Biological Interactions 257, pages 125-131.
Crossref
J L Steegmann, M Baccarani, M Breccia, L F Casado, V García-Gutiérrez, A Hochhaus, D-W Kim, T D Kim, H J Khoury, P Le Coutre, J Mayer, D Milojkovic, K Porkka, D Rea, G Rosti, S Saussele, R Hehlmann & R E Clark. (2016) European LeukemiaNet recommendations for the management and avoidance of adverse events of treatment in chronic myeloid leukaemia. Leukemia 30:8, pages 1648-1671.
Crossref
SHANSHAN DING, FEI LONG & SHUJUAN JIANG. (2016) Acute myocardial infarction following erlotinib treatment for NSCLC: A case report. Oncology Letters 11:6, pages 4240-4244.
Crossref
Lauren Caldemeyer, Michael Dugan, John Edwards & Luke Akard. (2016) Long-Term Side Effects of Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia. Current Hematologic Malignancy Reports 11:2, pages 71-79.
Crossref
Camilo A. Velásquez, Miguel González, Marie C. Berrouet & Nicolás Jaramillo. (2016) Cardiotoxicidad inducida por la quimioterapia desde las bases moleculares hasta la perspectiva clínica. Revista Colombiana de Cardiología 23:2, pages 104-111.
Crossref
Shabneez Hussain & Mohammad Usman Shaikh. (2015) Response and Adverse Effects of Nilotinib in Imatinib-resistant Chronic Myeloid Leukemia Patients: Data From a Developing Country. Clinical Therapeutics 37:11, pages 2449-2457.
Crossref
Rob Wallis, Mayel Gharanei & Helen Maddock. (2015) Predictivity of in vitro non-clinical cardiac contractility assays for inotropic effects in humans — A literature search. Journal of Pharmacological and Toxicological Methods 75, pages 62-69.
Crossref
Matthew Trendowski. (2015) PU-H71: An improvement on nature's solutions to oncogenic Hsp90 addiction. Pharmacological Research 99, pages 202-216.
Crossref
Liang Kong, Yue Wang, Xiao-Jing Wang, Xiao-Tong Wang, Yan Zhao, Li-Mei Wang & Zhe-Yu Chen. (2015) Retinoic acid ameliorates blood–brain barrier disruption following ischemic stroke in rats. Pharmacological Research 99, pages 125-136.
Crossref
Kimberly R. Doherty, Dominique R. Talbert, Patricia B. Trusk, Diarmuid M. Moran, Scott A. Shell & Sarah Bacus. (2015) Structural and functional screening in human induced-pluripotent stem cell-derived cardiomyocytes accurately identifies cardiotoxicity of multiple drug types. Toxicology and Applied Pharmacology 285:1, pages 51-60.
Crossref
Mark C. Munson. 2015. Antitargets and Drug Safety. Antitargets and Drug Safety 329 364 .
Miko Kawabata, Noriko Umemoto, Yasuhito Shimada, Yuhei Nishimura, Beibei Zhang, Junya Kuroyanagi, Masayuki Miyabe & Toshio Tanaka. (2015) Downregulation of Stanniocalcin 1 Is Responsible for Sorafenib-Induced Cardiotoxicity. Toxicological Sciences 143:2, pages 374-384.
Crossref
Carine E. HamoMichelle Weisfelner Bloom. (2015) Getting to the Heart of the Matter: An Overview of Cardiac Toxicity Related to Cancer Therapy. Clinical Medicine Insights: Cardiology 9s2, pages CMC.S19704.
Crossref
Christian Kollmannsberger, G. A. Bjarnason & Alain Ravaud. 2015. Kidney Cancer. Kidney Cancer 365 384 .
Luis León, Luis Miguel Antón-Aparicio, Emilio Esteban-González, Martin Lázaro-Quintela & Sergio Vázquez-Éstevez. 2015. Renal Cell Carcinoma. Renal Cell Carcinoma 377 416 .
Arezoo Daryadel, Anna Bogdanova, Max Gassmann, Xavier Mueller, Gregor Zünd, Burkhardt Seifert, Christine Lehalle, Nelly Frossard & Reza Tavakoli. (2014) Multikinase inhibitor sorafenib prevents pressure overload-induced left ventricular hypertrophy in rats by blocking the c-Raf/ERK1/2 signaling pathway. Journal of Cardiothoracic Surgery 9:1.
Crossref
Daniela Sicoli, Xuanmao Jiao, Xiaoming Ju, Marco Velasco-Velazquez, Adam Ertel, Sankar Addya, Zhiping Li, Sebastiano Andò, Alessandro Fatatis, Bishnuhari Paudyal, Massimo Cristofanilli, Mathew L. Thakur, Michael P. Lisanti & Richard G. Pestell. (2014) CCR5 Receptor Antagonists Block Metastasis to Bone of v-Src Oncogene–Transformed Metastatic Prostate Cancer Cell Lines. Cancer Research 74:23, pages 7103-7114.
Crossref
L. Mortara, G. Pera, E. Monti, S. Morbelli, F. Minuto, G. Sambuceti & M. Giusti. (2014) Efficacy of sorafenib and impact on cardiac function in patients with thyroid cancer: a retrospective analysis. Journal of Endocrinological Investigation 37:11, pages 1099-1108.
Crossref
Cristina Tintori, Annalaura Brai, Anna Lucia Fallacara, Roberta Fazi, Silvia Schenone & Maurizio Botta. (2014) Protein–protein interactions and human cellular cofactors as new targets for HIV therapy. Current Opinion in Pharmacology 18, pages 1-8.
Crossref
Judy Truong, Andrew T. Yan, Gemma Cramarossa & Kelvin K.W. Chan. (2014) Chemotherapy-Induced Cardiotoxicity: Detection, Prevention, and Management. Canadian Journal of Cardiology 30:8, pages 869-878.
Crossref
Jennifer A. Talarico, Rhonda L. Carter, Laurel A. Grisanti, Justine E. Yu, Ashley A. Repas & Douglas G. Tilley. (2014) β-Adrenergic Receptor-Dependent Alterations in Murine Cardiac Transcript Expression Are Differentially Regulated by Gefitinib In Vivo. PLoS ONE 9:6, pages e99195.
Crossref
Shirley A. Aguirre & Eileen R. Blasi. 2014. Predictive ADMET. Predictive ADMET 555 568 .
Hardip SandhuHelen Maddock. (2013) Molecular basis of cancer-therapy-induced cardiotoxicity: introducing microRNA biomarkers for early assessment of subclinical myocardial injury. Clinical Science 126:6, pages 377-400.
Crossref
Bum Soon Choi. (2014) Risks associated with sunitinib use and monitoring to improve patient outcomes. The Korean Journal of Internal Medicine 29:1, pages 23.
Crossref
Kerry Strong Russell. 2014. Evidence-Based Cardiology Consult. Evidence-Based Cardiology Consult 399 407 .
Nader Makki, Kristina Thiel & Francis MillerJr.Jr.. (2013) The Epidermal Growth Factor Receptor and Its Ligands in Cardiovascular Disease. International Journal of Molecular Sciences 14:10, pages 20597-20613.
Crossref
Rossana Berardi, Miriam Caramanti, Agnese Savini, Silvia Chiorrini, Chiara Pierantoni, Azzurra Onofri, Zelmira Ballatore, Mariagrazia De Lisa, Paola Mazzanti & Stefano Cascinu. (2013) State of the art for cardiotoxicity due to chemotherapy and to targeted therapies: A literature review. Critical Reviews in Oncology/Hematology 88:1, pages 75-86.
Crossref
Nicola Sgherza, Antonella Vita Russo Rossi, Paolo Colonna, Paola Carluccio, Mario Delia & Giorgina Specchia. (2013) Use of tyrosine kinase inhibitors in a patient with Brugada syndrome and chronic myeloid leukemia. International Journal of Hematology 98:4, pages 483-486.
Crossref
Hervé Spechbach, Philippe Morel, Kuntheavy Ing Lorenzini, Marie Besson, Laurent Gétaz, Henri Sunthorn & Yves Chalandon. (2013) Reversible ventricular arrythmia induced by dasatinib. Clinical Case Reports 1:1, pages 20-25.
Crossref
Kimberly A. Henderson, R. Brandon Borders, John B. Ross, Theresa B. Huwar, Calvin O. Travis, Brandon J. Wood, Zhenxu J. Ma, S. Peter Hong, Thomas M. Vinci & Brian M. Roche. (2013) Effects of tyrosine kinase inhibitors on rat isolated heart function and protein biomarkers indicative of toxicity. Journal of Pharmacological and Toxicological Methods 68:1, pages 150-159.
Crossref
T D Kim, D Rea, M Schwarz, P Grille, F E Nicolini, G Rosti, L Levato, F J Giles, H Dombret, T Mirault, H Labussière, R Lindhorst, W Haverkamp, I Buschmann, B Dörken & P D le Coutre. (2013) Peripheral artery occlusive disease in chronic phase chronic myeloid leukemia patients treated with nilotinib or imatinib. Leukemia 27:6, pages 1316-1321.
Crossref
Kunihiro Tsuji, Kenichi Takemura, Keisuke Minami, Ryota Teramoto, Keisuke Nakashima, Shinya Yamada, Hisashi Doyama, Hisanori Oiwake & Kenkou Hasatani. (2013) A case of rhabdomyolysis related to sorafenib treatment for advanced hepatocellular carcinoma. Clinical Journal of Gastroenterology 6:3, pages 255-257.
Crossref
Saurabh Aggarwal, Jasmine Kamboj & Rohit Arora. (2013) Chemotherapy-related cardiotoxicity. Therapeutic Advances in Cardiovascular Disease 7:2, pages 87-98.
Crossref
Harue Sasai, Kenichi Sakakura, Koichi Yuri, Hiroshi Wada, Kenshiro Arao, Hiroshi Funayama, Yoshitaka Sugawara, Atsushi Yamaguchi, Hideo Adachi, Shin-ichi Momomura & Junya Ako. (2012) Fractional flow reserve for a mild stenosis on the donor artery to chronic total occlusion. Cardiovascular Intervention and Therapeutics 28:2, pages 193-196.
Crossref
Barbara SchreierSindy RabeBettina SchneiderMaria BretschneiderSebastian RuppStefanie RuhsJoachim NeumannUwe RueckschlossMaria SibiliaMichael GotthardtClaudia GrossmannMichael Gekle. (2013) Loss of Epidermal Growth Factor Receptor in Vascular Smooth Muscle Cells and Cardiomyocytes Causes Arterial Hypotension and Cardiac Hypertrophy. Hypertension 61:2, pages 333-340.
Crossref
Philip S. Hall, Lauren C. Harshman, Sandy Srinivas & Ronald M. Witteles. (2013) The Frequency and Severity of Cardiovascular Toxicity From Targeted Therapy in Advanced Renal Cell Carcinoma Patients. JACC: Heart Failure 1:1, pages 72-78.
Crossref
Shenjun Zhu, Sharon M Cawley, Kenneth D Bloch & Paul L Huang. (2013) Trastuzumab and lapatinib differ in effects on calcium cycling and HER2 expression in human embryonic stem cell-derived cardiomyocytes. Cardiovascular System 1:1, pages 10.
Crossref
Carole Yolande PerrotDelphine JavelaudAlain Mauviel. (2013) Insights into the Transforming Growth Factor-β Signaling Pathway in Cutaneous Melanoma. Annals of Dermatology 25:2, pages 135.
Crossref
Qian Dong, Xiao-xing Fu, Li-li Du, Ning Zhao, Cheng-kun Xia, Kun-wu Yu, Long-xian Cheng & Yi-mei Du. (2013) Blocking of the Human Ether-à-go-go-Related Gene Channel by Imatinib Mesylate. Biological and Pharmaceutical Bulletin 36:2, pages 268-275.
Crossref
Marion Castel, Fabien Despas, Anouchka Modesto, Céline Gales, Benjamin Honton, Michel Galinier, Jean-Michel Senard & Atul Pathak. (2013) Effets indésirables cardiaques des chimiothérapies. La Presse Médicale 42:1, pages 26-39.
Crossref
F. Bianchi, E. Caffarri, S. Cavalli, C. Lagrasta, M. Musci, F. Quaini & M. Savi. (2013) Development and validation of an high performance liquid chromatography–tandem mass spectrometry method for the determination of imatinib in rat tissues. Journal of Pharmaceutical and Biomedical Analysis 73, pages 103-107.
Crossref
. 2013. Complications et Séquelles des Traitements en Cancérologie ORL. Complications et Séquelles des Traitements en Cancérologie ORL 125 147 .
Delphine Javelaud & Alain Mauviel. 2013. TGF-β in Human Disease. TGF-β in Human Disease 235 254 .
Giuseppe Procopio, Elena Verzoni, Isabella Testa, Nicola Nicolai, Roberto Salvioni & Filippo DeBraud. (2012) Experience with sorafenib in the treatment of advanced renal cell carcinoma. Therapeutic Advances in Urology 4:6, pages 303-313.
Crossref
Eduardo Gehling Bertoldi, Milena S. Marcolino, Luis Eduardo P. Rohde, Antonio Luiz Ribeiro & Carisi A. Polanczyk. (2012) Cost-Effectiveness of Routine Screening for Cardiac Toxicity in Patients Treated with Imatinib in Brazil. Value in Health Regional Issues 1:2, pages 180-183.
Crossref
Baichun Yang & Thomas Papoian. (2012) Tyrosine kinase inhibitor (TKI)‐induced cardiotoxicity: approaches to narrow the gaps between preclinical safety evaluation and clinical outcome. Journal of Applied Toxicology 32:12, pages 945-951.
Crossref
Mathieu Porceddu, Nelly Buron, Célestin Roussel, Gilles Labbe, Bernard Fromenty & Annie Borgne-Sanchez. (2012) Prediction of Liver Injury Induced by Chemicals in Human With a Multiparametric Assay on Isolated Mouse Liver Mitochondria. Toxicological Sciences 129:2, pages 332-345.
Crossref
Manuela Schmidinger & Jutta Bergler‐Klein. (2012) Therapy management of cardiovascular adverse events in the context of targeted therapy for metastatic renal cell carcinoma. International Journal of Urology 19:9, pages 796-804.
Crossref
Rodolfo Sacco, Irene Bargellini, Barbara Ginanni, Marco Bertini, Elena Bozzi, Emanuele Altomare, Valentina Battaglia, Antonio Romano, Emanuele Tumino, Matteo Di Biase, Giampaolo Bresci & Carlo Bartolozzi. (2011) Partial Response and Cardiovascular Recovery after Sorafenib Dose Reduction in a Multinodular HCC Patient. Journal of Gastrointestinal Cancer 43:S1, pages 89-92.
Crossref
Marek Svoboda, Alexandr Poprach, Svatopluk Dobes, Igor Kiss & Rostislav Vyzula. (2012) Cardiac Toxicity of Targeted Therapies Used in the Treatment for Solid Tumours: A Review. Cardiovascular Toxicology 12:3, pages 191-207.
Crossref
Aiping ZHOU. (2012) Management of sunitinib adverse events in renal cell carcinoma patients: The Asian experience. Asia-Pacific Journal of Clinical Oncology 8:2, pages 132-144.
Crossref
Martin Hohenegger. (2012) Drug induced rhabdomyolysis. Current Opinion in Pharmacology 12:3, pages 335-339.
Crossref
Zsolt Sarszegi, Eszter Bognar, Balazs Gaszner, Attila Kónyi, Ferenc GallyasJr.Jr., Balazs Sumegi & Zoltan Berente. (2012) BGP-15, a PARP-inhibitor, prevents imatinib-induced cardiotoxicity by activating Akt and suppressing JNK and p38 MAP kinases. Molecular and Cellular Biochemistry 365:1-2, pages 129-137.
Crossref
Tao Chen, Peter A. Stephens, Fiona K. Middleton & Nicola J. Curtin. (2012) Targeting the S and G2 checkpoint to treat cancer. Drug Discovery Today 17:5-6, pages 194-202.
Crossref
Foroogh Nejatollahi, Mahdi Asgharpour & Mansooreh Jaberipour. (2011) Down-regulation of vascular endothelial growth factor expression by anti-her2/neu single chain antibodies. Medical Oncology 29:1, pages 378-383.
Crossref
Ingrid M.E. Desar, Annemarie M.J. Thijs, Sasja F. Mulder, Cees J.J. Tack, Carla M.L. van Herpen & Winette T.A. van der Graaf. (2012) Weight loss induced by tyrosine kinase inhibitors of the vascular endothelial growth factor pathway. Anti-Cancer Drugs 23:2, pages 149-154.
Crossref
Julien EdelineElodie VauléonNathalie Rioux-LeclercqChristophe PerrinCécile Vigneau Karim BensalahBrigitte Laguerre. (2012) Safety and Efficacy of Sorafenib in Renal Cell Carcinoma. Cancer Growth and Metastasis 5, pages CGM.S7526.
Crossref
Christian Kollmannsberger, G. A. Bjarnason & Alain Ravaud. 2012. Kidney Cancer. Kidney Cancer 265 283 .
J.D. Cohen, J.E. Babiarz, R.M. Abrams, L. Guo, S. Kameoka, E. Chiao, J. Taunton & K.L. Kolaja. (2011) Use of human stem cell derived cardiomyocytes to examine sunitinib mediated cardiotoxicity and electrophysiological alterations. Toxicology and Applied Pharmacology 257:1, pages 74-83.
Crossref
Lynnette HowingtonKristina RiddlespergerDennis J. Cheek. (2011) Essential Nursing Competencies for Genetics and Genomics: Implications for Critical Care. Critical Care Nurse 31:5, pages e1-e7.
Crossref
Milena S. Marcolino, Eric Boersma, Nelma C.D. Clementino, Maria do Carmo P. Nunes, Márcia M. Barbosa, Maria Helena C.R. Silva, Marcel L. Geleijnse & Antonio L. Ribeiro. (2010) The duration of the use of imatinib mesylate is only weakly related to elevated BNP levels in chronic myeloid leukaemia patients. Hematological Oncology 29:3, pages 124-130.
Crossref
Moira Davenport & Mary Ann Howland. 2011. Challenging and Emerging Conditions in Emergency Medicine. Challenging and Emerging Conditions in Emergency Medicine 158 183 .
Antonio Pezzano. (2011) Importance of cancer therapies induced cardiotoxicity study. Journal of Cardiovascular Echography 21:2, pages 43-44.
Crossref
Sara Di Bella, Filippo Venturini, Giovanna Marrapese, Emiliana Tarenzi & Salvatore Siena. (2011) Cardiotoxicity of novel molecular targeted therapies of cancer. Journal of Cardiovascular Echography 21:2, pages 78-85.
Crossref
T. Naib, R.M. Steingart & C.L. Chen. (2011) Sorafenib-associated multivessel coronary artery vasospasmSorafenibassozierter Spasmus mehrer Koronararterien. Herz 36:4, pages 348-351.
Crossref
Houjian CaiDaniel A. SmithSanaz Memarzadeh, Clifford A. Lowell, Jonathan A. Cooper & Owen N. Witte. (2011) Differential transformation capacity of Src family kinases during the initiation of prostate cancer. Proceedings of the National Academy of Sciences 108:16, pages 6579-6584.
Crossref
Milena Soriano Marcolino, Antonio Luiz Ribeiro, Nelma C.D. Clementino, Maria do Carmo P. Nunes, Márcia M. Barbosa, Maria Helena C.R. Silva, Henrique N.S. Bittencourt, Marcel L. Geleijnse & Eric Boersma. (2011) The use of imatinib mesylate has no adverse effects on the heart function. Results of a pilot study in patients with chronic myeloid leukemia. Leukemia Research 35:3, pages 317-322.
Crossref
Lidia Boccardi, Daniela Cardinale, Maurizio Civelli, Chiara Lestuzzi, Carlo Materazzo, Nicola Maurea, Ines Monte, Stefano Oliva, Patrizia Piotti, Giuseppina Quattrocchi, Elisabetta Rossi & Giuseppe Toglia. (2011) Approccio cardiologico al paziente sottoposto a trattamento antitumorale. Documento primo. Journal of Cardiovascular Echography 21:1, pages 32-41.
Crossref
Andrés F. Buitrago, Luis E. Silva, Leidy P. Prada & Libardo Lobato. (2011) Derrame pericárdico con inminente taponamiento cardiaco secundario a inhibidor de la tirosina quinasa. Reporte de un caso. Revista Colombiana de Cardiología 18:2, pages 119-123.
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Thomas Force & Kyle L. Kolaja. (2011) Cardiotoxicity of kinase inhibitors: the prediction and translation of preclinical models to clinical outcomes. Nature Reviews Drug Discovery 10:2, pages 111-126.
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