Citations (110)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (9)
Cassandra C. Brooks, Lisa J. Martin, Valentina Pilipenko, Hua He, Grace K. LeMasters, James E. Lockey, David I. Bernstein, Patrick H. Ryan, Gurjit K. Khurana Hershey & Jocelyn M. Biagini Myers. (2021) NAT1 genetic variation increases asthma risk in children with secondhand smoke exposure. Journal of Asthma 58:3, pages 284-292.
Read now
Read now
Philip G. Board & M. W. Anders. (2021) Moonlighting in drug metabolism. Drug Metabolism Reviews 53:1, pages 76-99.
Read now
Read now
Jinping Gan, Shuguang Ma & Donglu Zhang. (2016) Non-cytochrome P450-mediated bioactivation and its toxicological relevance. Drug Metabolism Reviews 48:4, pages 473-501.
Read now
Read now
Félix Javier Jiménez-Jiménez, Hortensia Alonso-Navarro, Elena García-Martín & José A.G. Agúndez. (2016) NAT2 polymorphisms and risk for Parkinson’s disease: a systematic review and meta-analysis. Expert Opinion on Drug Metabolism & Toxicology 12:8, pages 937-946.
Read now
Read now
Jayaprakasam Bolleddula, Kevin DeMent, James P. Driscoll, Philip Worboys, Patrick J. Brassil & David L. Bourdet. (2014) Biotransformation and bioactivation reactions of alicyclic amines in drug molecules. Drug Metabolism Reviews 46:3, pages 379-419.
Read now
Read now
Lizania Borges Spinasse, Adalberto Rezende Santos, Philip Noel Suffys, Elizabeth Silaid Muxfeldt & Gil Fernando Salles. (2014) Different Phenotypes of the NAT2 Gene Influences Hydralazine Antihypertensive Response in Patients with Resistant Hypertension. Pharmacogenomics 15:2, pages 169-178.
Read now
Read now
Xavier Kubiak, Julien Dairou, Jean-Marie Dupret & Fernando Rodrigues-Lima. (2013) Crystal structure of arylamine N-acetyltransferases: insights into the mechanisms of action and substrate selectivity. Expert Opinion on Drug Metabolism & Toxicology 9:3, pages 349-362.
Read now
Read now
David W Hein. (2009) N-acetyltransferase SNPs: emerging concepts serve as a paradigm for understanding complexities of personalized medicine. Expert Opinion on Drug Metabolism & Toxicology 5:4, pages 353-366.
Read now
Read now
Lesley A Stanley & Edith Sim. (2008) Update on the Pharmacogenetics of NATs: Structural Considerations. Pharmacogenomics 9:11, pages 1673-1693.
Read now
Read now
Articles from other publishers (101)
Víctor Alejandro Paz-Rodríguez, Diana Judith Herrera-Vargas, Eneida Turiján-Espinoza, Miguel Ernesto Martínez-Leija, Emmanuel Rivera-López, Oswaldo Hernández-González, Daniel Zavala-Reyes, Mariana Haydee García-Hernández, Juan Manuel Vargas-Morales, Rosa del Carmen Milán-Segovia & Diana Patricia Portales-Pérez. (2024) Function and expression of N-acetyltransferases 1 and 2 are altered in lymphocytes in type 2 diabetes and obesity. Biochemistry and Biophysics Reports 38, pages 101716.
Crossref
Crossref
Xiaoya Ma, Yujie Li, Xufeng Zang, Jinping Guo, Wenqian Zhou, Junhui Han, Jing Liang, Panpan Wan, Hua Yang & Tianbo Jin. (2024) The landscape of very important pharmacogenes variants and potential clinical relevance in the Chinese Jingpo population: a comparative study with worldwide populations. Cancer Chemotherapy and Pharmacology 93:5, pages 481-496.
Crossref
Crossref
Chandra Choudhury, Melinder K. Gill, Courtney E. McAleese, Neville J. Butcher, Shyuan T. Ngo, Frederik J. Steyn & Rodney F. Minchin. (2024) The Arylamine N-Acetyltransferases as Therapeutic Targets in Metabolic Diseases Associated with Mitochondrial Dysfunction. Pharmacological Reviews 76:2, pages 300-320.
Crossref
Crossref
Sotiria Boukouvala, Giannoulis Fakis, Ioanna Stavrakaki, Elena Polycarpou, Nicola Laurieri & Edith Sim. 2024. Reference Module in Biomedical Sciences. Reference Module in Biomedical Sciences.
Yeo-Dim Park, Yoon-Jee Chae & Han-Joo Maeng. (2023) Investigation of N-Acetyltransferase 2-Mediated Drug Interactions of Amifampridine: In Vitro and In Vivo Evidence of Drug Interactions with Acetaminophen. Pharmaceutics 15:5, pages 1471.
Crossref
Crossref
Eleni‐Pavlina Karagianni, Evanthia Kontomina, Edward D. Lowe, Konstantinos Athanasopoulos, Georgia Papanikolaou, Vasiliki Garefalaki, Varvara Kotseli, Sofia Zaliou, Tom Grimaud, Konstantina Arvaniti, Maria‐Aggeliki Tsatiri, Giannoulis Fakis, Anthony E. Glenn, Pietro Roversi, Areej Abuhammad, Ali Ryan, Robert B. Sim, Edith Sim & Sotiria Boukouvala. (2022)
Fusarium verticillioides
NAT1
(
FDB2
)
N
‐malonyltransferase is structurally, functionally and phylogenetically distinct from its
N
‐acetyltransferase (
NAT
) homologues
. The FEBS Journal 290:9, pages 2412-2436.
Crossref
Crossref
Marta Eide, Anders Goksøyr, Fekadu Yadetie, Alejandra Gilabert, Zdenka Bartosova, Håvard G. Frøysa, Shirin Fallahi, Xiaokang Zhang, Nello Blaser, Inge Jonassen, Per Bruheim, Guttorm Alendal, Morten Brun, Cinta Porte & Odd André Karlsen. (2023) Integrative omics-analysis of lipid metabolism regulation by peroxisome proliferator-activated receptor a and b agonists in male Atlantic cod. Frontiers in Physiology 14.
Crossref
Crossref
Lukas Krähenbühl & Stephan Krähenbühl. (2023) Rats with Long-Term Cholestasis Have a Decreased Cytosolic but Maintained Mitochondrial Hepatic CoA Pool. International Journal of Molecular Sciences 24:5, pages 4365.
Crossref
Crossref
Zahraa K. Lawi, Mohammed Baqur S. Al-Shuhaib & Ibtissem Ben Amara. (2022) The rs1801280 SNP is associated with non-small cell lung carcinoma by exhibiting a highly deleterious effect on N-acetyltransferase 2. Journal of Cancer Research and Clinical Oncology 149:1, pages 147-157.
Crossref
Crossref
Fei Yan, Zhenhao Tian, Yonggang Yang, Xiangge Tian, Xiuyan Han, Lei Feng, Jingnan Cui & Xiaochi Ma. (2022) Fluorescence-based visual analysis and inhibitor screening of Arylamine N-acetyltransferase 2, a key enzyme for tuberculosis. Sensors and Actuators B: Chemical 373, pages 132714.
Crossref
Crossref
Yasuhiro Uno, Shotaro Uehara, Moe Ijiri, Hiroaki Kawaguchi, Atsushi Asano, Mitsuya Shiraishi, Kaito Banju, Norie Murayama & Hiroshi Yamazaki. (2022)
Molecular and Functional Characterization of
N
-Acetyltransferases in Common Marmosets and Pigs
. Drug Metabolism and Disposition 50:11, pages 1429-1433.
Crossref
Crossref
Anita Stojanović Marković, Matea Zajc Petranović, Marko Škobalj, Estella S. Poloni, Lana Pichler Oberški, Tatjana Škarić‐Jurić & Marijana Peričić Salihović. (2022)
From dietary adaptation in the past to drug metabolism of today: An example of
NAT
genes in the Croatian Roma
. American Journal of Biological Anthropology 178:1, pages 140-153.
Crossref
Crossref
Yasuhiro Uno, Shotaro Uehara & Hiroshi Yamazaki. (2022) Drug-oxidizing and conjugating non-cytochrome P450 (non-P450) enzymes in cynomolgus monkeys and common marmosets as preclinical models for humans. Biochemical Pharmacology 197, pages 114887.
Crossref
Crossref
Margaret O. James. 2022. Comprehensive Pharmacology. Comprehensive Pharmacology
563
584
.
Mariamena Arbitrio, Francesca Scionti, Maria Teresa Di Martino, Licia Pensabene, Pierfrancesco Tassone & Pierosandro Tagliaferri. 2022. Comprehensive Pharmacology. Comprehensive Pharmacology
657
697
.
Hang-Qin Zhu, Xiao-Ling Tang, Ren-Chao Zheng & Yu-Guo Zheng. (2021) Recent advancements in enzyme engineering via site-specific incorporation of unnatural amino acids. World Journal of Microbiology and Biotechnology 37:12.
Crossref
Crossref
R.P. Tiis, L.P. Osipova, E.R. Galieva, D.V. Lichman, E.N. Voronina, A.V. Melikhova, Y.L. Orlov & M.L. Filipenko. (2021) N-aсetyltransferase (NAT2) gene polymorphism and gene network analysis. Biomeditsinskaya Khimiya 67:3, pages 213-221.
Crossref
Crossref
Michael J. Doerksen, Robert S. Jones, Michael W. H. Coughtrie & Abby C. Collier. (2020) Parameterization of Microsomal and Cytosolic Scaling Factors: Methodological and Biological Considerations for Scalar Derivation and Validation. European Journal of Drug Metabolism and Pharmacokinetics 46:2, pages 173-183.
Crossref
Crossref
Xinning Liu, Yuanchang Liu, Guangjian Zhao, Yidan Zhang, Lu Liu, Juan Wang, Yifan Wang, Siyu Zhang, Xin Li, Dongliang Guo, Peng Wang & Ximing Xu. (2021) Biochemical Characterization of Arylamine N-acetyltransferases From Vibrio vulnificus. Frontiers in Microbiology 11.
Crossref
Crossref
Cheng-Jian Zheng, Edward Kalkreuter, Bo-Yi Fan, Yu-Chen Liu, Liao-Bin Dong & Ben Shen. (2020)
PtmC Catalyzes the Final Step of Thioplatensimycin, Thioplatencin, and Thioplatensilin Biosynthesis and Expands the Scope of Arylamine
N
-Acetyltransferases
. ACS Chemical Biology 16:1, pages 96-105.
Crossref
Crossref
Jennifer L. Dumouchel & Valerie M. Kramlinger. 2021. Enzyme Kinetics in Drug Metabolism. Enzyme Kinetics in Drug Metabolism
781
808
.
Roza Pavlovna Tiis, Ludmila Pavlovna Osipova, Daria Veniaminovna Lichman, Elena Nikolaevna Voronina & Maxim Leonidovich Filipenko. (2020) Studying polymorphic variants of the NAT2 gene (NAT2*5 and NAT2*7) in Nenets populations of Northern Siberia. BMC Genetics 21:S1.
Crossref
Crossref
Yasuhiro Uno, Norie Murayama & Hiroshi Yamazaki. (2020) Genetic variants of N-acetyltransferases 1 and 2 (NAT1 and NAT2) in cynomolgus and rhesus macaques. Biochemical Pharmacology 177, pages 113996.
Crossref
Crossref
Yasuhiro Uno & Hiroshi Yamazaki. (2020) mRNA levels of drug-metabolizing enzymes in 11 brain regions of cynomolgus macaques. Drug Metabolism and Pharmacokinetics 35:2, pages 248-252.
Crossref
Crossref
Hao Sun & Dennis Scott. 2020. Structural Biology in Drug Discovery. Structural Biology in Drug Discovery
567
585
.
Lei Feng, Jing Ning, Xiangge Tian, Chao Wang, Liyuan Zhang, Xiaochi Ma & Tony D. James. (2019) Fluorescent probes for bioactive detection and imaging of phase II metabolic enzymes. Coordination Chemistry Reviews 399, pages 213026.
Crossref
Crossref
Sotiria Boukouvala, Zoi Chasapopoulou, Despina Giannouri, Evanthia Kontomina, Nikolaos Marinakis, Sophia V. Rizou, Ioanna Stefani, Theodora Tsirka, Charlotte Veyssière, Sofia Zaliou, Audrey Sabbagh, Brigitte Crouau-Roy & Giannoulis Fakis. (2019) Population variability of rhesus macaque (Macaca mulatta) NAT1 gene for arylamine N-acetyltransferase 1: Functional effects and comparison with human. Scientific Reports 9:1.
Crossref
Crossref
Hikaru Nakashima, Ryoji Yoshida, Akiyuki Hirosue, Kenta Kawahara, Junki Sakata, Hidetaka Arita, Tatsuro Yamamoto, Ryo Toya, Ryuji Murakami, Akimitsu Hiraki, Masanori Shinohara, Takaaki Ito, Yoshikazu Kuwahara & Hideki Nakayama. (2019) Circulating miRNA-1290 as a potential biomarker for response to chemoradiotherapy and prognosis of patients with advanced oral squamous cell carcinoma: A single-center retrospective study. Tumor Biology 41:3, pages 101042831982685.
Crossref
Crossref
Peter van den Hurk & Harald M.I. Kerkkamp. (2019) Phylogenetic origins for severe acetaminophen toxicity in snake species compared to other vertebrate taxa. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 215, pages 18-24.
Crossref
Crossref
Martina Letizia Contente, Andrea Pinto, Francesco Molinari & Francesca Paradisi. (2018)
Biocatalytic
N
‐Acylation of Amines in Water Using an Acyltransferase from
Mycobacterium smegmatis
. Advanced Synthesis & Catalysis 360:24, pages 4814-4819.
Crossref
Crossref
Rodney F. Minchin, K. Johan Rosengren, Rachel Burow & Neville J. Butcher. (2018) Allosteric regulation of arylamine N-acetyltransferase 1 by adenosine triphosphate. Biochemical Pharmacology 158, pages 153-160.
Crossref
Crossref
Yasuhiro Uno, Norie Murayama & Hiroshi Yamazaki. (2018)
Molecular and Functional Characterization of
N
-Acetyltransferases NAT1 and NAT2 in Cynomolgus Macaque
. Chemical Research in Toxicology 31:11, pages 1269-1276.
Crossref
Crossref
Margit Winkler, Martina Geier, Steven P. Hanlon, Bernd Nidetzky & Anton Glieder. (2018) Human Enzymes for Organic Synthesis. Angewandte Chemie International Edition 57:41, pages 13406-13423.
Crossref
Crossref
Margit Winkler, Martina Geier, Steven P. Hanlon, Bernd Nidetzky & Anton Glieder. (2018) Humane Enzyme für die organische Synthese. Angewandte Chemie 130:41, pages 13592-13610.
Crossref
Crossref
Fleur Kleinpenning, Selma Eising, Tim Berkenbosch, Veronica Garzero, Judith M. Schaart & Kimberly M. Bonger. (2018)
Subcellular Protein Labeling by a Spatially Restricted Arylamine
N
-Acetyltransferase
. ACS Chemical Biology 13:8, pages 1932-1937.
Crossref
Crossref
Eneida Turiján-Espinoza, Rául Alejandro Salazar-González, Edith Elena Uresti-Rivera, Gloria Estela Hernández-Hernández, Montserrat Ortega-Juárez, Rosa Milán & Diana Portales-Pérez. (2018) A pilot study of the modulation of sirtuins on arylamine N-acetyltransferase 1 and 2 enzymatic activity. Acta Pharmaceutica Sinica B 8:2, pages 188-199.
Crossref
Crossref
N. Laurieri, E. Polycarpou & E. Sim. 2018. Comprehensive Toxicology. Comprehensive Toxicology
429
467
.
Xavier Kubiak, Romain Duval, Benjamin Pluvinage, Alain F Chaffotte, Jean‐Marie Dupret & Fernando Rodrigues‐Lima. (2016)
Xenobiotic‐metabolizing enzymes in
Bacillus anthracis
: molecular and functional analysis of a truncated arylamine
N
‐acetyltransferase isozyme
. British Journal of Pharmacology 174:14, pages 2174-2182.
Crossref
Crossref
Junguo Ma, Yiyi Feng, Siyu Jiang & Xiaoyu Li. (2017) Altered cellular metabolism of HepG2 cells caused by microcystin-LR. Environmental Pollution 225, pages 610-619.
Crossref
Crossref
Zhilin Luan, Tianlan Lu, Weihua Yue, Sjef Copray & Dai Zhang. (2017) Association between NAT2 polymorphisms and the risk of schizophrenia in a Northern Chinese Han population. Psychiatric Genetics 27:2, pages 71-75.
Crossref
Crossref
N. Laurieri & R. Delgoda. 2017. Pharmacognosy. Pharmacognosy
617
632
.
T. Bohnert, A. Patel, I. Templeton, Y. Chen, C. Lu, G. Lai, L. Leung, S. Tse, H. J. Einolf, Y.-H. Wang, M. Sinz, R. Stearns, R. Walsky, W. Geng, S. Sudsakorn, D. Moore, L. He, J. Wahlstrom, J. Keirns, R. Narayanan, D. Lang & X. Yang. (2016) Evaluation of a New Molecular Entity as a Victim of Metabolic Drug-Drug Interactions--an Industry Perspective. Drug Metabolism and Disposition 44:8, pages 1399-1423.
Crossref
Crossref
Alexander V. LyubimovDenis M. Grant. 2011. Encyclopedia of Drug Metabolism and Interactions. Encyclopedia of Drug Metabolism and Interactions
1
29
.
Stéphane Cauchi. (2016) La N-acétyltransférase 2 influence la sensibilité à l’insuline. Médecine des Maladies Métaboliques 10:3, pages 69-70.
Crossref
Crossref
Heloisa Helena Milioli, Renato Vimieiro, Carlos Riveros, Inna Tishchenko, Regina Berretta & Pablo Moscato. (2015) The Discovery of Novel Biomarkers Improves Breast Cancer Intrinsic Subtype Prediction and Reconciles the Labels in the METABRIC Data Set. PLOS ONE 10:7, pages e0129711.
Crossref
Crossref
Joshua W. Knowles, Weijia Xie, Zhongyang Zhang, Indumathi Chennemsetty, Themistocles L. Assimes, Jussi Paananen, Ola Hansson, James Pankow, Mark O. Goodarzi, Ivan Carcamo-Orive, Andrew P. Morris, Yii-Der I. Chen, Ville-Petteri Mäkinen, Andrea Ganna, Anubha Mahajan, Xiuqing Guo, Fahim Abbasi, Danielle M. Greenawalt, Pek Lum, Cliona Molony, Lars Lind, Cecilia Lindgren, Leslie J. Raffel, Philip S. Tsao, Eric E. Schadt, Jerome I. Rotter, Alan Sinaiko, Gerald Reaven, Xia Yang, Chao A. Hsiung, Leif Groop, Heather J. Cordell, Markku Laakso, Ke Hao, Erik Ingelsson, Timothy M. Frayling, Michael N. Weedon, Mark Walker & Thomas Quertermous. (2015) Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene. Journal of Clinical Investigation 125:4, pages 1739-1751.
Crossref
Crossref
G K LeMasters, G K Khurana Hershey, U Sivaprasad, L J Martin, V Pilipenko, M B Ericksen, J W Burkle, M A Lindsey, D I Bernstein, J E Lockey, J Gareri, A Lubetsky, G Koren & J M Biagini Myers. (2014) N-acetyltransferase 1 polymorphism increases cotinine levels in Caucasian children exposed to secondhand smoke: the CCAAPS birth cohort. The Pharmacogenomics Journal 15:2, pages 189-195.
Crossref
Crossref
Rodney F. Minchin & Neville J. Butcher. (2015) The role of lysine100 in the binding of acetylcoenzyme A to human arylamine N-acetyltransferase 1: Implications for other acetyltransferases. Biochemical Pharmacology 94:3, pages 195-202.
Crossref
Crossref
Ximing Xu, Inés Li de la Sierra-Gallay, Xavier Kubiak, Romain Duval, Alain F. Chaffotte, Jean-Marie Dupret, Ahmed Haouz & Fernando Rodrigues-Lima. (2015)
Insight into cofactor recognition in arylamine
N
-acetyltransferase enzymes: structure of
Mesorhizobium loti
arylamine
N
-acetyltransferase in complex with coenzyme A
. Acta Crystallographica Section D Biological Crystallography 71:2, pages 266-273.
Crossref
Crossref
Guangcai Ma, Na Cheng, Hao Su & Yongjun Liu. (2015) Exploring the substrate-assisted acetylation mechanism by UDP-linked sugar N-acetyltransferase from QM/MM calculations: the role of residue Asn84 and the effects of starting geometries. RSC Advances 5:10, pages 7781-7788.
Crossref
Crossref
Nicola Laurieri, Akane Kawamura, Isaac M Westwood, Amy Varney, Elizabeth Morris, Angela J Russell, Lesley A Stanley & Edith Sim. (2014) Differences between murine arylamine N-acetyltransferase type 1 and human arylamine N-acetyltransferase type 2 defined by substrate specificity and inhibitor binding. BMC Pharmacology and Toxicology 15:1.
Crossref
Crossref
Yumi Endo, Hiroko Yamashita, Satoru Takahashi, Shinya Sato, Nobuyasu Yoshimoto, Tomoko Asano, Yukari Hato, Yu Dong, Yoshitaka Fujii & Tatsuya Toyama. (2014) Immunohistochemical determination of the miR-1290 target arylamine N-acetyltransferase 1 (NAT1) as a prognostic biomarker in breast cancer. BMC Cancer 14:1.
Crossref
Crossref
R. Salazar-González, R. Gómez, S. Romano-Moreno, S. Medellín-Garibay, A. Núñez-Ruíz, M. Magaña-Aquino, R. C. Milán-Segovia & D. P. Portales-Pérez. (2014) Expression of NAT2 in immune system cells and the relation of NAT2 gene polymorphisms in the anti-tuberculosis therapy in Mexican mestizo population. Molecular Biology Reports 41:12, pages 7833-7843.
Crossref
Crossref
Angélique Cocaign, Xavier Kubiak, Ximing Xu, Guillaume Garnier, Inès Li de la Sierra-Gallay, Linh Chi-Bui, Julien Dairou, Florent Busi, Areej Abuhammad, Ahmed Haouz, Jean-Marie Dupret, Jean-Louis Herrmann & Fernando Rodrigues-Lima. (2014)
Structural and functional characterization of an arylamine
N
-acetyltransferase from the pathogen
Mycobacterium abscessus
: differences from other mycobacterial isoforms and implications for selective inhibition
. Acta Crystallographica Section D Biological Crystallography 70:11, pages 3066-3079.
Crossref
Crossref
Ellen M. McDonagh, Sotiria Boukouvala, Eleni Aklillu, David W. Hein, Russ B. Altman & Teri E. Klein. (2014) PharmGKB summary. Pharmacogenetics and Genomics 24:8, pages 409-425.
Crossref
Crossref
Verónica Ramírez-Alcántara & Marshall H. Montrose. (2014)
Acute murine colitis reduces colonic 5-aminosalicylic acid metabolism by regulation of
N
-acetyltransferase-2
. American Journal of Physiology-Gastrointestinal and Liver Physiology 306:11, pages G1002-G1010.
Crossref
Crossref
E Sim, A Abuhammad & A Ryan. (2014) Arylamine N‐acetyltransferases: from drug metabolism and pharmacogenetics to drug discovery. British Journal of Pharmacology 171:11, pages 2705-2725.
Crossref
Crossref
James E. Egleton, Cyrille C. Thinnes, Peter T. Seden, Nicola Laurieri, Siu Po Lee, Kate S. Hadavizadeh, Angelina R. Measures, Alan M. Jones, Sam Thompson, Amy Varney, Graham M. Wynne, Ali Ryan, Edith Sim & Angela J. Russell. (2014) Structure–activity relationships and colorimetric properties of specific probes for the putative cancer biomarker human arylamine N-acetyltransferase 1. Bioorganic & Medicinal Chemistry 22:11, pages 3030-3054.
Crossref
Crossref
Nicola Laurieri, Julien Dairou, James E. Egleton, Lesley A. Stanley, Angela J. Russell, Jean-Marie Dupret, Edith Sim & Fernando Rodrigues-Lima. (2014) From Arylamine N-Acetyltransferase to Folate-Dependent Acetyl CoA Hydrolase: Impact of Folic Acid on the Activity of (HUMAN)NAT1 and Its Homologue (MOUSE)NAT2. PLoS ONE 9:5, pages e96370.
Crossref
Crossref
Zhou J. Deng, Neville J. Butcher, Gysell M. Mortimer, Zhongfan Jia, Michael J. Monteiro, Darren J. Martin & Rodney F. Minchin. (2014)
Interaction of Human Arylamine
N
-Acetyltransferase 1 with Different Nanomaterials
. Drug Metabolism and Disposition 42:3, pages 377-383.
Crossref
Crossref
Theodora Tsirka, Sotiria Boukouvala, Bogos Agianian & Giannoulis Fakis. (2014) Polymorphism p.Val231Ile alters substrate selectivity of drug-metabolizing arylamine N-acetyltransferase 2 (NAT2) isoenzyme of rhesus macaque and human. Gene 536:1, pages 65-73.
Crossref
Crossref
Daniel R. Albaugh & Michael B. Fisher. 2014. Handbook of Metabolic Pathways of Xenobiotics. Handbook of Metabolic Pathways of Xenobiotics
1
35
.
Ahmad Faizal Abdull Razis, Noramaliza Mohd Noor & Nattaya Konsue. (2014) Induction of Epoxide Hydrolase, Glucuronosyl Transferase, and Sulfotransferase by Phenethyl Isothiocyanate in Male Wistar Albino Rats. BioMed Research International 2014, pages 1-5.
Crossref
Crossref
B.S. Raccor, A.M. Teitelbaum, J.C. Dinh & R.A. Totah. 2014. Reference Module in Chemistry, Molecular Sciences and Chemical Engineering. Reference Module in Chemistry, Molecular Sciences and Chemical Engineering.
Xiaotong Zhou, Zhiguo Ma, Dong Dong & Baojian Wu. (2013)
Arylamine
N
‐acetyltransferases: a structural perspective
. British Journal of Pharmacology 169:4, pages 748-760.
Crossref
Crossref
Christopher Olivares, Jidong Liang, Leif Abrell, Reyes Sierra‐Alvarez & Jim A. Field. (2013) Pathways of reductive 2,4‐dinitroanisole (DNAN) biotransformation in sludge. Biotechnology and Bioengineering 110:6, pages 1595-1604.
Crossref
Crossref
Hong Lu, Sumedha Gunewardena, Julia Y. Cui, Byunggil Yoo, Xiao-bo Zhong & Curtis D. Klaassen. (2013) RNA-Sequencing Quantification of Hepatic Ontogeny and Tissue Distribution of mRNAs of Phase II Enzymes in Mice. Drug Metabolism and Disposition 41:4, pages 844-857.
Crossref
Crossref
J. L. Houghton, K. D. Green, R. E. Pricer, A. S. Mayhoub & S. Garneau-Tsodikova. (2012) Unexpected N-acetylation of capreomycin by mycobacterial Eis enzymes. Journal of Antimicrobial Chemotherapy 68:4, pages 800-805.
Crossref
Crossref
Y. Endo, T. Toyama, S. Takahashi, N. Yoshimoto, M. Iwasa, T. Asano, Y. Fujii & H. Yamashita. (2012) miR-1290 and its potential targets are associated with characteristics of estrogen receptor -positive breast cancer. Endocrine Related Cancer 20:1, pages 91-102.
Crossref
Crossref
Audrey Sabbagh, Julie Marin, Charlotte Veyssi?re, Emilie Lecompte, Sotiria Boukouvala, Estella S Poloni, Pierre Darlu & Brigitte Crouau-Roy. (2013) Rapid birth-and-death evolution of the xenobiotic metabolizing NAT gene family in vertebrates with evidence of adaptive selection. BMC Evolutionary Biology 13:1, pages 62.
Crossref
Crossref
Rim Khlifi, Olfa Messaoud, Ahmed Rebai & Amel Hamza-Chaffai. (2013)
Polymorphisms in the Human Cytochrome P450 and Arylamine
N
-Acetyltransferase: Susceptibility to Head and Neck Cancers
. BioMed Research International 2013, pages 1-20.
Crossref
Crossref
Francisco Jose Forestiero, Leticia Cecon, Mario Hirouki Hirata, Fernando Fiuza de Melo, Rosilene Fressatti Cardoso, Alvaro Cerda & Rosario Dominguez Crespo Hirata. (2013) Relationship of NAT2, CYP2E1 and GSTM1/GSTT1 polymorphisms with mild elevation of liver enzymes in Brazilian individuals under anti-tuberculosis drug therapy. Clinica Chimica Acta 415, pages 215-219.
Crossref
Crossref
Areej Abuhammad, Elizabeth Fullam, Edward D. Lowe, David Staunton, Akane Kawamura, Isaac M. Westwood, Sanjib Bhakta, Alun Christopher Garner, David L. Wilson, Peter T. Seden, Stephen G. Davies, Angela J. Russell, Elspeth F. Garman & Edith Sim. (2012) Piperidinols That Show Anti-Tubercular Activity as Inhibitors of Arylamine N-Acetyltransferase: An Essential Enzyme for Mycobacterial Survival Inside Macrophages. PLoS ONE 7:12, pages e52790.
Crossref
Crossref
Alexander V. LyubimovRobert S. Foti, Dan A. Rock, Larry C. Wienkers & Jan L. Wahlstrom. 2011. Encyclopedia of Drug Metabolism and Interactions. Encyclopedia of Drug Metabolism and Interactions
1
68
.
Alexander V. LyubimovRonald E. White. 2011. Encyclopedia of Drug Metabolism and Interactions. Encyclopedia of Drug Metabolism and Interactions
1
40
.
Ricardo Martins Ramos, Janaína Menezes Perez, Luis André Baptista & Hermes Luís Neubauer de Amorim. (2012) Interaction of wild type, G68R and L125M isoforms of the arylamine-N-acetyltransferase from Mycobacterium tuberculosis with isoniazid: a computational study on a new possible mechanism of resistance. Journal of Molecular Modeling 18:9, pages 4013-4024.
Crossref
Crossref
Alexander V. LyubimovMark P. Grillo. 2011. Encyclopedia of Drug Metabolism and Interactions. Encyclopedia of Drug Metabolism and Interactions
1
56
.
David A. Kingery & Scott A. Strobel. (2011) Analysis of Enzymatic Transacylase Brønsted Studies with Application to the Ribosome. Accounts of Chemical Research 45:4, pages 495-503.
Crossref
Crossref
Xavier Kubiak, Benjamin Pluvinage, Inès Li de la Sierra-Gallay, Patrick Weber, Ahmed Haouz, Jean-Marie Dupret & Fernando Rodrigues-Lima. (2012)
Purification, crystallization and preliminary X-ray characterization of
Bacillus cereus
arylamine
N
-acetyltransferase 3 [(BACCR)NAT3]
. Acta Crystallographica Section F Structural Biology and Crystallization Communications 68:2, pages 196-198.
Crossref
Crossref
Edith Sim, Giannoulis Fakis, Nicola Laurieri & Sotiria Boukouvala. 2012. Current Concepts in Drug Metabolism and Toxicology. Current Concepts in Drug Metabolism and Toxicology
169
205
.
Fernando Rodrigues-Lima, Julien Dairou, Florent Busi & Jean-Marie Dupret. 2012. Cell Signaling & Molecular Targets in Cancer. Cell Signaling & Molecular Targets in Cancer
23
35
.
Benjamin Pluvinage, In's Li de la Sierra-Gallay, Xavier Kubiak, Ximing Xu, Julien Dairou, Jean-Marie Dupret & Fernando Rodrigues-Lima. (2011)
The
Bacillus anthracis
arylamine
N
-acetyltransferase ((BACAN)NAT1) that inactivates sulfamethoxazole, reveals unusual structural features compared with the other NAT isoenzymes
. FEBS Letters 585:24, pages 3947-3952.
Crossref
Crossref
Chen Bing, Cao Xiaomeia & Li Jinhenga. (2011)
Gene dose effect of
NAT2
variants on the pharmacokinetics of isoniazid and acetylisoniazid in healthy Chinese subjects
. dmdi 26:3, pages 113-118.
Crossref
Crossref
P. E. Almeida Da Silva & J. C. Palomino. (2011) Molecular basis and mechanisms of drug resistance in Mycobacterium tuberculosis: classical and new drugs. Journal of Antimicrobial Chemotherapy 66:7, pages 1417-1430.
Crossref
Crossref
A. Gutierrez, M. Elez, O. Clermont, E. Denamur & I. Matic. (2011) Escherichia coli YafP protein modulates DNA damaging property of the nitroaromatic compounds. Nucleic Acids Research 39:10, pages 4192-4201.
Crossref
Crossref
Marco A. RamosRosa E. MaresErick D. AvalosAnaid HernándezRogelio HernándezRodrigo LamedaAnalleli E. MalváezCarla A. RodríguezRosario Rodríguez. (2011)
Pharmacogenetic Screening of
N
-Acetyltransferase 2, Thiopurine
S
-Methyltransferase, and 5,10-Methylene-Tetrahydrofolate Reductase Polymorphisms in Northwestern Mexicans
. Genetic Testing and Molecular Biomarkers 15:5, pages 351-355.
Crossref
Crossref
Marc Campayo, Nuria Viñolas, Alfons Navarro, Enric Carcereny, Francesc Casas, Bernat Gel, Tania Diaz, Josep Maria Gimferrer, Ramon M. Marrades, Jose Ramirez & Mariano Monzo. (2011) Single Nucleotide Polymorphisms in Tobacco Metabolism and DNA Repair Genes and Prognosis in Resected Non-Small-Cell Lung Cancer. Journal of Surgical Research 167:1, pages e5-e12.
Crossref
Crossref
Sankha S. Basu, Clementina Mesaros, Stacy L. Gelhaus & Ian A. Blair. (2011) Stable Isotope Labeling by Essential Nutrients in Cell Culture for Preparation of Labeled Coenzyme A and Its Thioesters. Analytical Chemistry 83:4, pages 1363-1369.
Crossref
Crossref
Anthony E. Glenn, Eleni P. Karagianni, Αntigona Ulndreaj & Sotiria Boukouvala. (2010)
Comparative genomic and phylogenetic investigation of the xenobiotic metabolizing arylamine
N
‐acetyltransferase enzyme family
. FEBS Letters 584:14, pages 3158-3164.
Crossref
Crossref
Nicola LaurieriMatthew H. J. CrawfordAkane KawamuraIsaac M. WestwoodJames RobinsonAi M. FletcherStephen G. DaviesEdith SimAngela J. Russell. (2010)
Small Molecule Colorimetric Probes for Specific Detection of Human Arylamine
N
-Acetyltransferase 1, a Potential Breast Cancer Biomarker
. Journal of the American Chemical Society 132:10, pages 3238-3239.
Crossref
Crossref
Pedro J. Ballester, Isaac Westwood, Nicola Laurieri, Edith Sim & W. Graham Richards. (2009)
Prospective virtual screening with Ultrafast Shape Recognition: the identification of novel inhibitors of arylamine
N
-acetyltransferases
. Journal of The Royal Society Interface 7:43, pages 335-342.
Crossref
Crossref
Karin E. Broberg, Margareta Warholm, Håkan Tinnerberg, Anna Axmon, Bo A. Jönsson, Carl Johan Sennbro, Margareta Littorin & Agneta Rannug. (2010) The GSTP1 Ile105 Val polymorphism modifies the metabolism of toluene di-isocyanate. Pharmacogenetics and Genomics 20:2, pages 104-111.
Crossref
Crossref
Larissa Wakefield, Sotiria Boukouvala & Edith Sim. (2010) Characterisation of CpG methylation in the upstream control region of mouse Nat2: Evidence for a gene–environment interaction in a polymorphic gene implicated in folate metabolism. Gene 452:1, pages 16-21.
Crossref
Crossref
Wen Cao, Diana Strnatka, Charlene A. McQueen, Robert J. Hunter & Robert P. Erickson. (2010) N-acetyltransferase 2 activity and folate levels. Life Sciences 86:3-4, pages 103-106.
Crossref
Crossref
E. Sim, E. Fullam & L. Wakefield. 2010. Comprehensive Toxicology. Comprehensive Toxicology
385
412
.
Carrie M. Mosher & Michael H. Court. 2010. Comparative and Veterinary Pharmacology. Comparative and Veterinary Pharmacology
49
77
.
Susan Kadlubar & Fred F. Kadlubar. 2010. Enzyme- and Transporter-Based Drug-Drug Interactions. Enzyme- and Transporter-Based Drug-Drug Interactions
3
25
.
Florence Malka, Julien Dairou, Nilusha Ragunathan, Jean‐Marie Dupret & Fernando Rodrigues‐Lima. (2009)
Mechanisms and kinetics of human arylamine
N
‐acetyltransferase 1 inhibition by disulfiram
. The FEBS Journal 276:17, pages 4900-4908.
Crossref
Crossref
Marta Martins, Fernando Rodrigues-Lima, Julien Dairou, Aazdine Lamouri, Fabienne Malagnac, Philippe Silar & Jean-Marie Dupret. (2009) An Acetyltransferase Conferring Tolerance to Toxic Aromatic Amine Chemicals. Journal of Biological Chemistry 284:28, pages 18726-18733.
Crossref
Crossref
A Ametzazurra, E Larrea, M P Civeira, J Prieto & R Aldabe. (2008) Implication of human N-α-acetyltransferase 5 in cellular proliferation and carcinogenesis. Oncogene 27:58, pages 7296-7306.
Crossref
Crossref
Edith Sim, Nathan Lack, Chan-Ju Wang, Hilary Long, Isaac Westwood, Elizabeth Fullam & Akane Kawamura. (2008) Arylamine N-acetyltransferases: Structural and functional implications of polymorphisms. Toxicology 254:3, pages 170-183.
Crossref
Crossref