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Hemoglobin
international journal for hemoglobin research
Volume 31, 2007 - Issue 4
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Original Article

Plasma and Urine Hydroxyurea Levels Might be Useful in the Management of Adult Sickle Cell Disease

Dora Bachir Treatment Center of Sickle Cell Anemia, AP-HP, Hôpital Henri Mondor, Créteil, France
,
Anne Hulin Laboratory of Pharmacology and Toxicology, AP-HP, Hôpital Henri Mondor, Créteil, FranceCorrespondence[email protected]
,
Estelle Huet Laboratory of Pharmacology and Toxicology, AP-HP, Hôpital Henri Mondor, Créteil, France
,
Anoosha Habibi Treatment Center of Sickle Cell Anemia, AP-HP, Hôpital Henri Mondor, Créteil, France
,
Ruben Nzouakou Treatment Center of Sickle Cell Anemia, AP-HP, Hôpital Henri Mondor, Créteil, France
,
Madjeline El Mahrab Laboratory of Pharmacology and Toxicology, AP-HP, Hôpital Henri Mondor, Créteil, France
,
Alain Astier Laboratory of Pharmacology and Toxicology, AP-HP, Hôpital Henri Mondor, Créteil, France
&
Frédéric Galacteros Treatment Center of Sickle Cell Anemia, AP-HP, Hôpital Henri Mondor, Créteil, France; Université Paris 12, Faculté de Médecine, AP-HP, Hôpital Henri Mondor, Créteil, France
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Pages 417-425 | Received 13 Oct 2006, Accepted 12 Mar 2007, Published online: 07 Jul 2009

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Weizhi Lin, Cesar Ruiz, Matan Aroosh, Hadar Ben-Yoav & Qiang Huang. (2023) Multiresolution functional characterization and correction of biofouling for improved biosensing efficacy. IISE Transactions 0:0, pages 1-13.
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Winfred C Wang. (2008) The pharmacotherapy of sickle cell disease. Expert Opinion on Pharmacotherapy 9:17, pages 3069-3082.
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Articles from other publishers (15)

Abhishek Gour, Ashish Dogra, Priya Wazir, Gurdarshan Singh & Utpal Nandi. (2020) A highly sensitive UPLC-MS/MS method for hydroxyurea to assess pharmacokinetic intervention by phytotherapeutics in rats. Journal of Chromatography B 1154, pages 122283.
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Purnendu Kumar Pathak, Anil Kumar & Bhim Bali Prasad. (2019) Functionalized nitrogen doped graphene quantum dots and bimetallic Au/Ag core-shell decorated imprinted polymer for electrochemical sensing of anticancerous hydroxyurea. Biosensors and Bioelectronics 127, pages 10-18.
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Tiphaine Legrand, Marie-Georgine Rakotoson, Frédéric Galactéros, Pablo Bartolucci & Anne Hulin. (2017) Determination of hydroxyurea in human plasma by HPLC-UV using derivatization with xanthydrol. Journal of Chromatography B 1064, pages 85-91.
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Anu Marahatta & Russell E. Ware. (2017) Hydroxyurea: Analytical techniques and quantitative analysis. Blood Cells, Molecules, and Diseases 67, pages 135-142.
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Xin Hai, Meihua Guo, Chunlu Gao & Jin Zhou. (2017) Quantification of hydroxyurea in human plasma by HPLC–MS/MS and its application to pharmacokinetics in patients with chronic myeloid leukaemia. Journal of Pharmaceutical and Biomedical Analysis 137, pages 213-219.
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Anu Marahatta, Vandana Megaraj, Patrick T McGann, Russell E Ware & Kenneth D R Setchell. (2016) Stable-Isotope Dilution HPLC–Electrospray Ionization Tandem Mass Spectrometry Method for Quantifying Hydroxyurea in Dried Blood Samples. Clinical Chemistry 62:12, pages 1593-1601.
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Darcielle Bruna Dias Elias, Teresa Maria de Jesus Ponte Carvalho, Janete Eliza de Sá Soares & Romélia Pinheiro Gonçalves. (2014) Standardization method for measurement of hydroxyurea by Ultra High Efficiency Liquid Chromatography in plasma of patients with sickle cell disease. Brazilian Journal of Pharmaceutical Sciences 50:3, pages 621-628.
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Annette Wilisch-Neumann, Doreen Pachow, Maren Wallesch, Astrid Petermann, Frank D. Böhmer, Elmar Kirches & Christian Mawrin. (2014) Re-evaluation of cytostatic therapies for meningiomas in vitro. Journal of Cancer Research and Clinical Oncology 140:8, pages 1343-1352.
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Pablo Bartolucci & Frédéric Galactéros. (2012) Clinical management of adult sickle-cell disease. Current Opinion in Hematology 19:3, pages 149-155.
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Ines Paule, Hind Sassi, Anoosha Habibi, Kim PD Pham, Dora Bachir, Frédéric Galactéros, Pascal Girard, Anne Hulin & Michel Tod. (2011) Population pharmacokinetics and pharmacodynamics of hydroxyurea in sickle cell anemia patients, a basis for optimizing the dosing regimen. Orphanet Journal of Rare Diseases 6:1.
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Akito Nozaki, Kazushi Numata, Manabu Morimoto, Masaaki Kondo, Kazuya Sugimori, Satoshi Morita, Eiji Miyajima, Masanori Ikeda, Nobuyuki Kato, Shin Maeda & Katsuaki Tanaka. (2010) Hydroxyurea Suppresses HCV Replication in Humans: A Phase I Trial of Oral Hydroxyurea in Chronic Hepatitis C Patients. Antiviral Therapy 15:8, pages 1179-1183.
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Trine Juul, Anna Malolepszy, Karen Dybkær, Rune Kidmose, Jan Trige Rasmussen, Gregers Rom Andersen, Hans Erik Johnsen, Jan-Elo Jørgensen & Stig Uggerhøj Andersen. (2010) The in Vivo Toxicity of Hydroxyurea Depends on Its Direct Target Catalase. Journal of Biological Chemistry 285:28, pages 21411-21415.
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Hind Sassi, Dora Bachir, Anoosha Habibi, Alain Astier, Frédéric Galactéros & Anne Hulin. (2010) No effect of CYP450 and P‐glycoprotein on hydroxyurea in vitro metabolism. Fundamental & Clinical Pharmacology 24:1, pages 83-90.
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David K. Scott, Kathleen Neville & Uttam Garg. 2010. Clinical Applications of Mass Spectrometry. Clinical Applications of Mass Spectrometry 279 287 .
Tayeb Kettani, Frédéric Cotton, Béatrice Gulbis, Alina Ferster & Alain Kumps. (2009) Plasma hydroxyurea determined by gas chromatography–mass spectrometry. Journal of Chromatography B 877:4, pages 446-450.
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