Citations (25)
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George P. Patrinos, David H. K Chui, Ross C. Hardison & Martin H. Steinberg. (2021) Strategies to improve pharmacogenomic-guided treatment options for patients with β-hemoglobinopathies. Expert Review of Hematology 14:10, pages 883-885.
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Alexandra Kolliopoulou, Stavroula Siamoglou, Anne John, Argyro Sgourou, Alexandra Kourakli, Argiris Symeonidis, Efthymia Vlachaki, Panagiota Chalkia, Stamatia Theodoridou, Bassam R. Ali, Theodora Katsila, George P. Patrinos & Adamantia Papachatzopoulou. (2019) Role of Genomic Biomarkers in Increasing Fetal Hemoglobin Levels Upon Hydroxyurea Therapy and in β-Thalassemia Intermedia: A Validation Cohort Study. Hemoglobin 43:1, pages 27-33.
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Marium Husain, Amber D Hartman & Payal Desai. (2017) Pharmacogenomics of sickle cell disease: steps toward personalized medicine. Pharmacogenomics and Personalized Medicine 10, pages 261-265.
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Christina N Kontoghiorghe & George J Kontoghiorghes. (2016) Efficacy and safety of iron-chelation therapy with deferoxamine, deferiprone, and deferasirox for the treatment of iron-loaded patients with non-transfusion-dependent thalassemia syndromes. Drug Design, Development and Therapy 10, pages 465-481.
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Aikaterini Gravia, Vasiliki Chondrou, Alexandra Kolliopoulou, Alexandra Kourakli, Anne John, Argyris Symeonidis, Bassam R Ali, Argyro Sgourou, Adamantia Papachatzopoulou, Theodora Katsila & George P Patrinos. (2016) Correlation of SIN3A Genomic Variants with β-Hemoglobinopathies Disease Severity and Hydroxyurea Treatment Efficacy. Pharmacogenomics 17:16, pages 1785-1793.
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Mehran Karimi, Parisa Jooya, Sezaneh Haghpanah, Maral Mokhtari, Narges Rezaei, Maede Fath & Shirin Parand. (2016) Evaluation of the Relationship Between Hb F Levels and Nucleated Red Blood Cells with Morbidity in Non Transfusion-Dependent Thalassemia Patients. Hemoglobin 40:4, pages 250-256.
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Constantina Chalikiopoulou, Anastasia-Gerasimoula Tavianatou, Argyro Sgourou, Alexandra Kourakli, Dimitra Kelepouri, Maria Chrysanthakopoulou, Vasiliki-Kaliopi Kanelaki, Evangelos Mourdoukoutas, Stavroula Siamoglou, Anne John, Argyris Symeonidis, Bassam R Ali, Theodora Katsila, Adamantia Papachatzopoulou & George P Patrinos. (2016) Genomic variants in the ASS1 gene, involved in the Nitric Oxide Biosynthesis and Signaling Pathway, Predict Hydroxyurea Treatment Efficacy in Compound Sickle Cell Disease/β-Thalassemia Patients. Pharmacogenomics 17:4, pages 393-403.
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Yu-Chi Chou, Ruei-Lin Chen, Zheng-Sheng Lai, Jen-Shin Song, Yu-Sheng Chao & Che-Kun James Shen. (2015) Pharmacological Induction of Human Fetal Globin Gene in Hydroxyurea-Resistant Primary Adult Erythroid Cells. Molecular and Cellular Biology 35:14, pages 2541-2553.
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Aikaterini Gravia, Vasiliki Chondrou, Argyro Sgourou, Ioanna Papantoni, Joseph Borg, Theodora Katsila, Adamantia Papachatzopoulou & George P Patrinos. (2014) Individualizing Fetal Hemoglobin Augmenting Therapy for β-Type Hemoglobinopathies Patients. Pharmacogenomics 15:10, pages 1355-1364.
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Christina Tafrali, Arsinoi Paizi, Joseph Borg, Milena Radmilovic, Marina Bartsakoulia, Emily Giannopoulou, Olga Giannakopoulou, Maja Stojiljkovic-Petrovic, Branka Zukic, Konstantinos Poulas, Eleana F Stavrou, Polyxeni Lambropoulou, Alexandra Kourakli, Alexander E Felice, Adamantia Papachatzopoulou, Sjaak Philipsen, Sonja Pavlovic, Marianthi Georgitsi & George P Patrinos. (2013) Genomic Variation in the MAP3K5 Gene is Associated with β-Thalassemia Disease Severity and Hydroxyurea Treatment Efficacy. Pharmacogenomics 14:5, pages 469-483.
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Joseph Borg, Marios Phylactides, Marina Bartsakoulia, Christina Tafrali, Carsten Lederer, Alexander E Felice, Adamantia Papachatzopoulou, Alexandra Kourakli, Eleana F Stavrou, Soteroula Christou, Jun Hou, Sophia Karkabouna, Christina Lappa-Manakou, Zeliha Özgur, Wilfred van IJcken, Marieke von Lindern, Frank G Grosveld, Marianthi Georgitsi, Marina Kleanthous, Sjaak Philipsen & George P Patrinos. (2012)
KLF10 Gene Expression is Associated with High Fetal Hemoglobin Levels and with Response to Hydroxyurea Treatment in β-Hemoglobinopathy Patients. Pharmacogenomics 13:13, pages 1487-1500.
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Eleni Konstantinou, Ioannis Pashalidis, Annita Kolnagou & George J. Kontoghiorghes. (2011) Interactions Of Hydroxycarbamide (Hydroxyurea) With Iron And Copper: Implications On Toxicity and Therapeutic Strategies. Hemoglobin 35:3, pages 237-246.
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Adamantia Papachatzopoulou, Alexandra Kourakli, Eleana F. Stavrou, Ekaterini Fragou, Apostolos Vantarakis, George P. Patrinos & Aglaia Athanassiadou. (2010) Region-Specific Genetic Heterogeneity of HBB Mutation Distribution in South-Western Greece. Hemoglobin 34:4, pages 333-342.
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Alessio Squassina, Mirko Manchia, Vangelis G Manolopoulos, Mehmet Artac, Christina Lappa-Manakou, Sophia Karkabouna, Konstantinos Mitropoulos, Maria Del Zompo & George P Patrinos. (2010) Realities and Expectations of Pharmacogenomics and Personalized Medicine: Impact of Translating Genetic Knowledge into Clinical Practice. Pharmacogenomics 11:8, pages 1149-1167.
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George J. Kontoghiorghes, Aspasia Spyrou & Annita Kolnagou. (2010) Iron Chelation Therapy in Hereditary Hemochromatosis and Thalassemia Intermedia: Regulatory and Non Regulatory Mechanisms of Increased Iron Absorption. Hemoglobin 34:3, pages 251-264.
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Articles from other publishers (10)
Roberto Gambari, Aliyu Dahiru Waziri, Hemali Goonasekera & Emmanuel Peprah. (2024) Pharmacogenomics of Drugs Used in β-Thalassemia and Sickle-Cell Disease: From Basic Research to Clinical Applications. International Journal of Molecular Sciences 25:8, pages 4263.
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Kariofyllis Karamperis, Maria T. Tsoumpeli, Fotios Kounelis, Maria Koromina, Christina Mitropoulou, Catia Moutinho & George P. Patrinos. (2021) Genome-based therapeutic interventions for β-type hemoglobinopathies. Human Genomics 15:1.
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Zheng-Sheng Lai, Teng-Kuang Yeh, Yu-Chi Chou, Tsu Hsu, Cheng-Tai Lu, Fang-Chun Kung, Ming-Yen Hsieh, Chun-Hung Lin, Chiung-Tong Chen, Che-Kun James Shen & Weir-Torn Jiaang. (2021) Potent and orally active purine-based fetal hemoglobin inducers for treating β-thalassemia and sickle cell disease. European Journal of Medicinal Chemistry 209, pages 112938.
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George Kontoghiorghes & Christina Kontoghiorghe. (2020) Iron and Chelation in Biochemistry and Medicine: New Approaches to Controlling Iron Metabolism and Treating Related Diseases. Cells 9:6, pages 1456.
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Mohsen S. Elalfy, Nayera H.K. El Sherif, Tarek M. Kamal & Nihal H. Aly. (2017) Klf10 Gene, a Secondary Modifier and a Pharmacogenomic Biomarker of Hydroxyurea Treatment Among Patients With Hemoglobinopathies. Journal of Pediatric Hematology/Oncology 39:3, pages e155-e162.
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Nicoletta Bianchi, Cristiano Chiarabelli, Cristina Zuccato, Ilaria Lampronti, Monica Borgatti, Gabriele Amari, Maurizio Delcanale, Francesco Chiavilli, Eugenia Prus, Eitan Fibach & Roberto Gambari. (2015) Erythroid differentiation ability of butyric acid analogues: Identification of basal chemical structures of new inducers of foetal haemoglobin. European Journal of Pharmacology 752, pages 84-91.
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Aikaterini Gravia, Vasiliki Chondrou, Theodora Katsila & George P. Patrinos. 2015. Preventive and Predictive Genetics: Towards Personalised Medicine. Preventive and Predictive Genetics: Towards Personalised Medicine
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Belinda Giardine, Joseph Borg, Douglas R Higgs, Kenneth R Peterson, Sjaak Philipsen, Donna Maglott, Belinda K Singleton, David J Anstee, A Nazli Basak, Barnaby Clark, Flavia C Costa, Paula Faustino, Halyna Fedosyuk, Alex E Felice, Alain Francina, Renzo Galanello, Monica V E Gallivan, Marianthi Georgitsi, Richard J Gibbons, Piero C Giordano, Cornelis L Harteveld, James D Hoyer, Martin Jarvis, Philippe Joly, Emmanuel Kanavakis, Panagoula Kollia, Stephan Menzel, Webb Miller, Kamran Moradkhani, John Old, Adamantia Papachatzopoulou, Manoussos N Papadakis, Petros Papadopoulos, Sonja Pavlovic, Lucia Perseu, Milena Radmilovic, Cathy Riemer, Stefania Satta, Iris Schrijver, Maja Stojiljkovic, Swee Lay Thein, Jan Traeger-Synodinos, Ray Tully, Takahito Wada, John S Waye, Claudia Wiemann, Branka Zukic, David H K Chui, Henri Wajcman, Ross C Hardison & George P Patrinos. (2011) Systematic documentation and analysis of human genetic variation in hemoglobinopathies using the microattribution approach. Nature Genetics 43:4, pages 295-301.
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George P. Patrinos & Stylianos E. Antonarakis. 2010. Vogel and Motulsky's Human Genetics. Vogel and Motulsky's Human Genetics
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Pierre‐Olivier Gaudreau, Xiaoduan Weng, Ghislain Cournoyer, Louise Robin, Carmen Gagnon & Denis Soulières. (2009) Treatment with hydroxyurea in a patient compound heterozygote for a high oxygen affinity hemoglobin and β‐thalassemia minor. American Journal of Hematology 84:11, pages 766-768.
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