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Hemoglobin
international journal for hemoglobin research
Volume 32, 2008 - Issue 1-2
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Original

The Role of Zinc, Copper and Iron in the Pathogenesis of Diabetes and Diabetic Complications: Therapeutic Effects by Chelators

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Pages 135-145 | Published online: 07 Jul 2009

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Zhidong Liu, Miao Wang, Chunbo Zhang, Shigao Zhou & Guang Ji. (2022) Molecular Functions of Ceruloplasmin in Metabolic Disease Pathology. Diabetes, Metabolic Syndrome and Obesity 15, pages 695-711.
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Saideh Fakharzadeh, Somayeh Kalanaky, Maryam Hafizi, Mohammad Hassan Nazaran & Homeira Zardooz. (2019) DIBc, a nanochelating-based nano metal-organic framework, shows anti-diabetic effects in high-fat diet and streptozotocin-induced diabetic rats. International Journal of Nanomedicine 14, pages 2145-2156.
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Ashgan Abdalla Alghobashy, Usama M Alkholy, Mohamed A Talat, Nermin Abdalmonem, Ahmed Zaki, Ihab A Ahmed & Randa H Mohamed. (2018) Trace elements and oxidative stress in children with type 1 diabetes mellitus. Diabetes, Metabolic Syndrome and Obesity 11, pages 85-92.
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Meghdad Pirsaheb, Nazir Fattahi, Kiomars Sharafi, Razieh Khamotian & Zahra Atafar. (2016) Essential and toxic heavy metals in cereals and agricultural products marketed in Kermanshah, Iran, and human health risk assessment. Food Additives & Contaminants: Part B 9:1, pages 15-20.
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Giuseppina Marrazzo , Ignazio Barbagallo , Fabio Galvano, Michele Malaguarnera, Diego Gazzolo, Alessandro Frigiola, Nicolantonio D’Orazio & Giovanni Li Volti. (2014) Role of Dietary and Endogenous Antioxidants in Diabetes. Critical Reviews in Food Science and Nutrition 54:12, pages 1599-1616.
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T. B. Grammer, M. E. Kleber, G. Silbernagel, S. Pilz, H. Scharnagl, E. Lerchbaum, A. Tomaschitz, W. Koenig & W. März. (2014) Copper, ceruloplasmin, and long-term cardiovascular and total mortality (The Ludwigshafen Risk and Cardiovascular Health Study). Free Radical Research 48:6, pages 706-715.
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Ramazan Sert, Ayşen Höl, Aslıhan Arslan Kartal, Abdullah Akdoğan, Aydan Elçi, Jameel Ahmed Baig, Umit Divrikli & Latif Elçi. (2013) Simultaneous Solid Phase Chelate Extraction for Ultratrace Determination of Copper, Nickel, and Zinc by Microsample Injection System Coupled Flame Atomic Absorption Spectrometry. Analytical Letters 46:16, pages 2570-2582.
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Ganiyu Oboh, Ayodeji A. Olabiyi & Ayodele J. Akinyemi. (2013) Inhibitory effect of aqueous extract of different parts of unripe pawpaw (Carica papaya) fruit on Fe2+-induced oxidative stress in rat pancreas in vitro. Pharmaceutical Biology 51:9, pages 1165-1174.
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Giancarlo Aldini, Giulio Vistoli, Milan Stefek, N. Chondrogianni, Tilman Grune, Jolanta Sereikaite, Izabela Sadowska-Bartosz & Grzegorz Bartosz. (2013) Molecular strategies to prevent, inhibit, and degrade advanced glycoxidation and advanced lipoxidation end products. Free Radical Research 47:sup1, pages 93-137.
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Pramod Singh, Jagmohan S. Negi, M.S.M. Rawat & Geeta Joshi nee Pant. (2012) Determination of trace elements in Rheum moorcroftianum by AAS. Natural Product Research 26:2, pages 161-166.
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Heather C Hatcher, Ravi N Singh, Frank M Torti & Suzy V Torti. (2009) Synthetic and Natural Iron Chelators: Therapeutic Potential and Clinical Use. Future Medicinal Chemistry 1:9, pages 1643-1670.
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Wei Wei, Qiuju Liu, Yi Tan, Lucheng Liu, Xiaokun Li & Lu Cai. (2009) Oxidative Stress, Diabetes, and Diabetic Complications. Hemoglobin 33:5, pages 370-377.
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Natalia Quiroz, Nicole Rivas, Talía del Pozo, Jason Burkhead, Miriam Suazo, Mauricio González & Mauricio Latorre. (2015) Transcriptional activation of glutathione pathways and role of glucose homeostasis during copper imbalance. BioMetals 28:2, pages 321-328.
Crossref
Francisco Javier Perez-Vazquez, Rogelio Flores-Ramirez, Angeles Catalina Ochoa-Martinez, Sandra Teresa Orta-Garcia, Berenice Hernandez-Castro, Leticia Carrizalez-Yañez & Iván N. Pérez-Maldonado. (2014) Concentrations of persistent organic pollutants (POPs) and heavy metals in soil from San Luis Potosí, México. Environmental Monitoring and Assessment 187:1.
Crossref
Hui Chen, Chao Tan, Zan Lin & Tong Wu. (2014) The diagnostics of diabetes mellitus based on ensemble modeling and hair/urine element level analysis. Computers in Biology and Medicine 50, pages 70-75.
Crossref
Khanrin P. Vashum, Mark McEvoy, Abul Hasnat Milton, Md. Rafiqul Islam, Stephen Hancock & John Attia. (2014) Is Serum Zinc Associated with Pancreatic Beta Cell Function and Insulin Sensitivity in Pre-Diabetic and Normal Individuals? Findings from the Hunter Community Study. PLoS ONE 9:1, pages e83944.
Crossref
Joseph Fomusi Ndisang, Alfredo Vannacci & Sharad Rastogi. (2014) Oxidative Stress and Inflammation in Obesity, Diabetes, Hypertension, and Related Cardiometabolic Complications. Oxidative Medicine and Cellular Longevity 2014, pages 1-3.
Crossref
Matthew K McElwee, Lindsey A Ho, Jeff W Chou, Marjolein V Smith & Jonathan H Freedman. (2013) Comparative toxicogenomic responses of mercuric and methyl-mercury. BMC Genomics 14:1.
Crossref
Fatma Bozkurt, Recep Tekin, Serda Gulsun, Ömer Satıcı, Ozcan Deveci & Salih Hosoglu. (2013) The levels of copper, zinc and magnesium in type II diabetic patients complicated with foot infections. International Journal of Diabetes in Developing Countries 33:3, pages 165-169.
Crossref
George Awuku Asare, Shiloh Osae, Ezekiel Nii Noye Nortey, Faisal King Yambire, Elsie Amedonu, Derick Doku & Yvonne Annan. (2013) Evaluation of serum metallothionein-1, selenium, zinc, and copper in Ghanaian type 2 diabetes mellitus patients. International Journal of Diabetes in Developing Countries 33:2, pages 86-95.
Crossref
Jiancheng Xu, Wei Xu, Hanxin Yao, Weixia Sun, Qi Zhou & Lu Cai. (2013) Associations of Serum and Urinary Magnesium with the Pre-Diabetes, Diabetes and Diabetic Complications in the Chinese Northeast Population. PLoS ONE 8:2, pages e56750.
Crossref
Jiancheng Xu, Qi Zhou, Gilbert Liu, Yi Tan & Lu Cai. (2013) Analysis of Serum and Urinal Copper and Zinc in Chinese Northeast Population with the Prediabetes or Diabetes with and without Complications. Oxidative Medicine and Cellular Longevity 2013, pages 1-11.
Crossref
R. Jaffe. 2013. Bioactive Food as Dietary Interventions for Diabetes. Bioactive Food as Dietary Interventions for Diabetes 339 353 .
Hui Chen & Chao Tan. (2011) Prediction of Type-2 Diabetes Based on Several Element Levels in Blood and Chemometrics. Biological Trace Element Research 147:1-3, pages 67-74.
Crossref
Salem A. Habib & Eman M. Othman. (2012) In vitro upregulation of erythrocytes glucose uptake by Rhaphnus sativa extract in diabetic patients. Biochimie 94:5, pages 1206-1212.
Crossref
Prathima Sindhu, Beena Shetty, K Sudha & Gayathri Rao. (2012) Role of Redox Metals, Oxidative Protein Products and Antioxidant Potentials of Thiols in Diabetic Retinopathy. Journal of Medical Biochemistry 31:2, pages 126-130.
Crossref
O Savu, C Ionescu-Tirgoviste, V Atanasiu, L Gaman, R Papacocea & I Stoian. (2012) Increase in Total Antioxidant Capacity of Plasma despite High Levels of Oxidative Stress in Uncomplicated Type 2 Diabetes Mellitus. Journal of International Medical Research 40:2, pages 709-716.
Crossref
Lena Olsén, P. Monica Lind & Lars Lind. (2012) Gender differences for associations between circulating levels of metals and coronary risk in the elderly. International Journal of Hygiene and Environmental Health 215:3, pages 411-417.
Crossref
Ryoji Nagai, David B. Murray, Thomas O. Metz & John W. Baynes. (2012) Chelation: A Fundamental Mechanism of Action of AGE Inhibitors, AGE Breakers, and Other Inhibitors of Diabetes Complications. Diabetes 61:3, pages 549-559.
Crossref
Maísa Silva, Cintia Lopes de Brito Magalhães, Riva de Paula Oliveira, Marcelo Eustáquio Silva & Maria Lucia Pedrosa. (2011) Differential expression of iron metabolism proteins in diabetic and diabetic iron‐supplemented rat liver. Journal of Biochemical and Molecular Toxicology 26:3, pages 123-129.
Crossref
Anna Bryland, Anders Wieslander, Ola Carlsson, Thomas Hellmark & Gabriela Godaly. (2011) Citrate treatment reduces endothelial death and inflammation under hyperglycaemic conditions. Diabetes and Vascular Disease Research 9:1, pages 42-51.
Crossref
Petr Babula, Michal Masarik, Vojtech Adam, Tomas Eckschlager, Marie Stiborova, Libuse Trnkova, Helena Skutkova, Ivo Provaznik, Jaromir Hubalek & Rene Kizek. (2012) Mammalian metallothioneins: properties and functions. Metallomics 4:8, pages 739.
Crossref
Noha M. El Husseiny, Elham Sobhy Said, Naglaa El Shahat Mohamed & Azza Ismail Othman. (2011) Impact of Trace Element Changes on Dehydroepiandrosterone Sulfate in Healthy and Diabetic States among Middle-Age and Elderly Egyptians. Biological Trace Element Research 143:3, pages 1451-1460.
Crossref
Crescencio Rodríguez Flores, Mónica Preciado Puga, Katarzyna Wrobel, Ma. Eugenia Garay Sevilla & Kazimierz Wrobel. (2011) Trace elements status in diabetes mellitus type 2: Possible role of the interaction between molybdenum and copper in the progress of typical complications. Diabetes Research and Clinical Practice 91:3, pages 333-341.
Crossref
Vangelis Kondylis, Yang Tang, Florian Fuchs, Michael Boutros & Catherine Rabouille. (2011) Identification of ER Proteins Involved in the Functional Organisation of the Early Secretory Pathway in Drosophila Cells by a Targeted RNAi Screen. PLoS ONE 6:2, pages e17173.
Crossref
Maísa Silva, Larissa de Freitas Bonomo, Riva de Paula Oliveira, Wanderson Geraldo de Lima, Marcelo Eustáquio Silva & Maria Lucia Pedrosa. (2011) Effects of the interaction of diabetes and iron supplementation on hepatic and pancreatic tissues, oxidative stress markers, and liver peroxisome proliferator-activated receptor-α expression. Journal of Clinical Biochemistry and Nutrition 49:2, pages 102-108.
Crossref
Richard K. Kasama. (2010) Trace Minerals in Patients with End‐Stage Renal Disease. Seminars in Dialysis 23:6, pages 561-570.
Crossref
Mostafa Khajeh, Ali Reza Akbari Moghaddam & Esmael Sanchooli. (2009) Application of Doehlert Design in the Optimization of Microwave-Assisted Extraction for Determination of Zinc and Copper in Cereal Samples Using FAAS. Food Analytical Methods 3:3, pages 133-137.
Crossref
Mostafa Khajeh & Esmael Sanchooli. (2009) Optimization of Microwave-Assisted Extraction Procedure for Zinc and Iron Determination in Celery by Box–Behnken Design. Food Analytical Methods 3:2, pages 75-79.
Crossref
El-Nabarawy. (2010) α-Lipoic Acid Therapy Modulates Serum Levels of Some Trace Elements and Antioxidants in Type 2 Diabetic Patients. American Journal of Pharmacology and Toxicology 5:3, pages 152-158.
Crossref
Frank BarileLouis Trombetta. 2010. Clinical Toxicology. Clinical Toxicology 324 352 .
Sílvia Chaves, Ratomir Jelic, Catarina Mendonça, Marta Carrasco, Yutaka Yoshikawa, Hiromu Sakurai & M. Amélia Santos. (2010) Complexes of hydroxy(thio)pyrone and hydroxy(thio)pyridinone with Zn( ii ) and Mo( vi ). Thermodynamic stability and insulin-mimetic activity . Metallomics 2:3, pages 220-227.
Crossref
Anna BŁażewicz, Grażyna Orlicz-Szczęsna, Andrzej Prystupa & Piotr Szczęsny. (2010) Use of ion chromatography for the determination of selected metals in blood serum of patients with type 2 diabetes. Journal of Trace Elements in Medicine and Biology 24:1, pages 14-19.
Crossref
Douglas B Kell. (2009) Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases. BMC Medical Genomics 2:1.
Crossref
Alena Viktorínová, Eva Tošerová, Marián Križko & Zdenka Ďuračková. (2009) Altered metabolism of copper, zinc, and magnesium is associated with increased levels of glycated hemoglobin in patients with diabetes mellitus. Metabolism 58:10, pages 1477-1482.
Crossref
Erin E. Battin & Julia L. Brumaghim. (2009) Antioxidant Activity of Sulfur and Selenium: A Review of Reactive Oxygen Species Scavenging, Glutathione Peroxidase, and Metal-Binding Antioxidant Mechanisms. Cell Biochemistry and Biophysics 55:1, pages 1-23.
Crossref
Mostafa Khajeh. (2009) Optimization of microwave-assisted extraction procedure for zinc and copper determination in food samples by Box-Behnken design. Journal of Food Composition and Analysis 22:4, pages 343-346.
Crossref
Nicholas A. Veldhuis, Ann P. Gaeth, Richard B. Pearson, Kipros Gabriel & James Camakaris. (2009) The multi-layered regulation of copper translocating P-type ATPases. BioMetals 22:1, pages 177-190.
Crossref
John W. Baynes & David B. Murray. (2009) The Metal Chelators, Trientine and Citrate, Inhibit the Development of Cardiac Pathology in the Zucker Diabetic Rat. Experimental Diabetes Research 2009, pages 1-6.
Crossref
Hadla S. Ferreira, Ana C.N. Santos, Lindomar A. Portugal, Antonio C.S. Costa, Manuel Miró & Sérgio L.C. Ferreira. (2008) Pre-concentration procedure for determination of copper and zinc in food samples by sequential multi-element flame atomic absorption spectrometry. Talanta 77:1, pages 73-76.
Crossref
Adriano Sartori, Humberto M. Garay-Malpartida, Maria F. Forni, Robert I. Schumacher, Fernando Dutra, Mari C. Sogayar & Etelvino J. H. Bechara. (2008) Aminoacetone, a Putative Endogenous Source of Methylglyoxal, Causes Oxidative Stress and Death to Insulin-Producing RINm5f Cells. Chemical Research in Toxicology 21:9, pages 1841-1850.
Crossref

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