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Drug Development and Industrial Pharmacy Volume 34, 2008 - Issue 1
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Research Article

Preparation, Optimization, and Characterization of Topotecan Loaded PEGylated Liposomes Using Factorial Design

Amir Masoud Vali Department of Pharmaceutics, Shaheed Beheshti University of Medical Sciences, Tehran, Iran
,
Taiebeh Toliyat Department of Pharmaceutics, Tehran University of Medical Sciences, Tehran, Iran
,
Bijan Shafaghi Department of Toxicology and Pharmacology, School of Pharmacy, Tehran, Iran; Pharmaceutical Research Center, Shaheed Beheshti University of Medical Sciences, Tehran, Iran
&
Simin Dadashzadeh Department of Pharmaceutics, School of Pharmacy, Tehran, Iran; Pharmaceutical Research Center, Shaheed Beheshti University of Medical Sciences, Tehran, Iran
Pages 10-23 | Published online: 25 Sep 2008

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Tahir Emre Yalcin, Sibel Ilbasmis-Tamer, Burçin Ibisoglu, Aysun Özdemir, Mustafa Ark & Sevgi Takka. (2018) Gemcitabine hydrochloride-loaded liposomes and nanoparticles: comparison of encapsulation efficiency, drug release, particle size, and cytotoxicity. Pharmaceutical Development and Technology 23:1, pages 76-86.
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Ankit Jain & Sanjay K. Jain. (2016) Multipronged, strategic delivery of paclitaxel-topotecan using engineered liposomes to ovarian cancer. Drug Development and Industrial Pharmacy 42:1, pages 136-149.
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Azadeh Haeri, Saeed Sadeghian, Shahram Rabbani, Maryam Sotoudeh Anvari, Mohammad Erfan & Simin Dadashzadeh. (2012) PEGylated estradiol benzoate liposomes as a potential local vascular delivery system for treatment of restenosis. Journal of Microencapsulation 29:1, pages 83-94.
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Bin Du, Ying Yan, Ying Li, ShuYu Wang & ZhenZhong Zhang. (2010) Preparation and passive target of 5-fluorouracil solid lipid nanoparticles. Pharmaceutical Development and Technology 15:4, pages 346-353.
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Articles from other publishers (15)

Hadeel M. Bayoumi & Mayson H. Alkhatib. (2022) Incorporation of topotecan into sesame oil - Nanoemulsion potentiates its cytotoxic effect in cancer cells. Journal of Drug Delivery Science and Technology 75, pages 103614.
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Zhiyong Zhang, Yan Pan, Yan Zhao, Mudan Ren, Yarui Li, Guifang Lu, Kaichun Wu & Shuixiang He. (2021) Topotecan-loaded thermosensitive nanocargo for tumor therapy: In vitro and in vivo analyses. International Journal of Pharmaceutics 606, pages 120871.
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Zaynab Fatfat, Maamoun Fatfat & Hala Gali-Muhtasib. (2021) Therapeutic potential of thymoquinone in combination therapy against cancer and cancer stem cells. World Journal of Clinical Oncology 12:7, pages 522-543.
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R. Xing, O. Mustapha, T. Ali, M. Rehman, S. S. Zaidi, A. Baseer, S. Batool, M. Mukhtiar, S. Shafique, M. Malik, S. Sohail, Z. Ali, F. Zahid, A. Zeb, F. Shah, A. Yousaf & F. Din. (2021) Development, Characterization, and Evaluation of SLN-Loaded Thermoresponsive Hydrogel System of Topotecan as Biological Macromolecule for Colorectal Delivery. BioMed Research International 2021, pages 1-14.
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Hongtao Xu, Yan Li, James W. Paxton & Zimei Wu. (2021) Co-Delivery Using pH-Sensitive Liposomes to Pancreatic Cancer Cells: the Effects of Curcumin on Cellular Concentration and Pharmacokinetics of Gemcitabine. Pharmaceutical Research 38:7, pages 1209-1219.
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Mirel Cabrera, Nicole Lecot, Marcelo Fernández, J. P. Gambini, Williams Porcal & Pablo Cabral. (2021) 99mTc Stearyl 6-(benzylidenehydrazinyl) nicotinamide Liposomes as Tumor Permeability Evaluation Tracer. AAPS PharmSciTech 22:3.
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Ankit Jain, Pooja Hurkat & Sanjay K. Jain. (2019) Development of liposomes using formulation by design: Basics to recent advances. Chemistry and Physics of Lipids 224, pages 104764.
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Didem Ag Seleci, Viktor Maurer, Frank Stahl, Thomas Scheper & Georg Garnweitner. (2019) Rapid Microfluidic Preparation of Niosomes for Targeted Drug Delivery. International Journal of Molecular Sciences 20:19, pages 4696.
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Stella Tsermentseli, Konstantinos Kontogiannopoulos, Vassilios Papageorgiou & Andreana Assimopoulou. (2018) Comparative Study of PEGylated and Conventional Liposomes as Carriers for Shikonin. Fluids 3:2, pages 36.
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Hongtao Xu, James Paxton, Joanne Lim, Yan Li, Wenli Zhang, Linda Duxfield & Zimei Wu. (2014) Development of High-Content Gemcitabine PEGylated Liposomes and Their Cytotoxicity on Drug-Resistant Pancreatic Tumour Cells. Pharmaceutical Research 31:10, pages 2583-2592.
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Hongtao Xu, James Paxton, Joanne Lim, Yan Li & Zimei Wu. (2014) Development of a gradient high performance liquid chromatography assay for simultaneous analysis of hydrophilic gemcitabine and lipophilic curcumin using a central composite design and its application in liposome development. Journal of Pharmaceutical and Biomedical Analysis 98, pages 371-378.
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Vladimir Torchilin. 2012. Long Acting Injections and Implants. Long Acting Injections and Implants 263 293 .
L.G. Souza, E.J. Silva, A.L.L. Martins, M.F. Mota, R.C. Braga, E.M. Lima, M.C. Valadares, S.F. Taveira & R.N. Marreto. (2011) Development of topotecan loaded lipid nanoparticles for chemical stabilization and prolonged release. European Journal of Pharmaceutics and Biopharmaceutics 79:1, pages 189-196.
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Azadeh Haeri, Saeed Sadeghian, Shahram Rabbani, Maryam Sotoudeh Anvari, Mohammad Ali Boroumand & Simin Dadashzadeh. (2011) Use of remote film loading methodology to entrap sirolimus into liposomes: Preparation, characterization and in vivo efficacy for treatment of restenosis. International Journal of Pharmaceutics 414:1-2, pages 16-27.
Crossref
Simin Dadashzadeh, Katayoun Derakhshandeh & Farshad Hoseini Shirazi. (2008) 9-Nitrocamptothecin polymeric nanoparticles: cytotoxicity and pharmacokinetic studies of lactone and total forms of drug in rats. Anti-Cancer Drugs 19:8, pages 805-811.
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