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Inhalation Toxicology
International Forum for Respiratory Research
Volume 18, 2006 - Issue 10
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Research Article

The Effect of Morphological Variability on Surface Deposition Densities of Inhaled Particles in Human Bronchial and Acinar Airways

Werner Hofmann Division of Physics and Biophysics, Department of Molecular Biology, University of Salzburg, Salzburg, Austria
,
Renate Winkler-Heil Division of Physics and Biophysics, Department of Molecular Biology, University of Salzburg, Salzburg, Austria
&
Imre Balásházy Health and Environmental Physics Department, KFKI Atomic Energy Research Institute, Budapest, Hungary
Pages 809-819 | Received 04 Nov 2005, Accepted 06 Apr 2006, Published online: 06 Oct 2008

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Renate Winkler-Heil, Majid Hussain & Werner Hofmann. (2021) Predictions of inter- and intra-lobar deposition patterns of inhaled particles in a five-lobe lung model . Inhalation Toxicology 33:3, pages 96-112.
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Péter Füri, Werner Hofmann, Ágnes Jókay, Imre Balásházy, Mona Moustafa, Blanka Czitrovszky, Gábor Kudela & Árpád Farkas. (2017) Comparison of airway deposition distributions of particles in healthy and diseased workers in an Egyptian industrial site. Inhalation Toxicology 29:4, pages 147-159.
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Renate Winkler-Heil & Werner Hofmann. (2016) Modeling particle deposition in the Balb/c mouse respiratory tract. Inhalation Toxicology 28:4, pages 180-191.
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Renate Winkler-Heil, George Ferron & Werner Hofmann. (2014) Calculation of hygroscopic particle deposition in the human lung. Inhalation Toxicology 26:3, pages 193-206.
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Imre Balásházy, Alpár Horváth, Zoltán Sárkány, árpád Farkas & Werner Hofmann. (2009) Simulation and minimisation of the airway deposition of airborne bacteria. Inhalation Toxicology 21:12, pages 1021-1029.
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Werner Hofmann. (2009) Modelling particle deposition in human lungs: modelling concepts and comparison with experimental data. Biomarkers 14:sup1, pages 59-62.
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Imre Balásházy, Werner Hofmann, Árpád Farkas & Balázs G. Madas. (2008) Three-Dimensional Model for Aerosol Transport and Deposition in Expanding and Contracting Alveoli. Inhalation Toxicology 20:6, pages 611-621.
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Articles from other publishers (22)

Xudong Zhou, Yaning Li, Hao Miao, Ya Zhang, Aibing Yu, Fen Huang, Renjie Li & Zhenbo Tong. (2024) Numerical study on the effect of the realistic mouth-inhaler positions on orally inhaled drug delivery in pediatric intersubject upper airways. Powder Technology 432, pages 119163.
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Huanhuan Jiang, Xiang Gao, Yong Gao & Yatao Liu. (2023) Current Knowledge and Challenges of Particle Size Measurements of Mainstream E-Cigarette Aerosols and Their Implication on Respiratory Dosimetry. Journal of Respiration 3:1, pages 7-28.
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Maurizio Gualtieri, Massimo Berico, Maria Grollino, Giuseppe Cremona, Teresa La Torretta, Antonella Malaguti, Ettore Petralia, Milena Stracquadanio, Massimo Santoro, Barbara Benassi, Antonio Piersanti, Andrea Chiappa, Manuele Bernabei & Gabriele Zanini. (2022) Emission Factors of CO2 and Airborne Pollutants and Toxicological Potency of Biofuels for Airplane Transport: A Preliminary Assessment. Toxics 10:10, pages 617.
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Khaled Talaat, Adam Hecht & Jinxiang Xi. (2021) A comparison of CFPD, compartment, and uniform distribution models for radiation dosimetry of radionuclides in the lung. Journal of Radiological Protection 41:4, pages 739-763.
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Elif Özlü. (2021) Assessment of exposure effects of indoor particles in different microenvironments. Air Quality, Atmosphere & Health 14:12, pages 2029-2046.
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Lukas Pichelstorfer, Renate Winkler-Heil, Michael Boy & Werner Hofmann. (2021) Aerosol dynamics simulations of the anatomical variability of e-cigarette particle and vapor deposition in a stochastic lung. Journal of Aerosol Science 158, pages 105706.
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Werner Hofmann. (2020) Regional Deposition: Deposition Models. Journal of Aerosol Medicine and Pulmonary Drug Delivery 33:5, pages 239-248.
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Werner Hofmann & Renate Winkler-Heil. (2020) CELLULAR DOSE DISTRIBUTIONS OF INHALED RADON PROGENY AMONG DIFFERENT LOBES OF THE HUMAN LUNG. Radiation Protection Dosimetry 188:4, pages 444-463.
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Vu Khac Hoang Bui, Ju-Young Moon, Minhe Chae, Duckshin Park & Young-Chul Lee. (2020) Prediction of Aerosol Deposition in the Human Respiratory Tract via Computational Models: A Review with Recent Updates. Atmosphere 11:2, pages 137.
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Kaveh Ahookhosh, Shadi Yaqoubi, Mousa Mohammadpourfard, Hamed Hamishehkar & Habib Aminfar. (2019) Experimental investigation of aerosol deposition through a realistic respiratory airway replica: An evaluation for MDI and DPI performance. International Journal of Pharmaceutics 566, pages 157-172.
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Ingeborg Kooter, Marit Ilves, Mariska Gröllers-Mulderij, Evert Duistermaat, Peter C. Tromp, Frieke Kuper, Pia Kinaret, Kai Savolainen, Dario Greco, Piia Karisola, Joseph Ndika & Harri Alenius. (2019) Molecular Signature of Asthma-Enhanced Sensitivity to CuO Nanoparticle Aerosols from 3D Cell Model. ACS Nano 13:6, pages 6932-6946.
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Miloslav Belka, Frantisek Lizal, Jan Jedelsky, Jakub Elcner, Philip K. Hopke & Miroslav Jicha. (2018) Deposition of glass fibers in a physically realistic replica of the human respiratory tract. Journal of Aerosol Science 117, pages 149-163.
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Renate Winkler-Heil, Lukas Pichelstorfer & Werner Hofmann. (2017) Aerosol dynamics model for the simulation of hygroscopic growth and deposition of inhaled NaCl particles in the human respiratory tract. Journal of Aerosol Science 113, pages 212-226.
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Anita Chvatal, Árpád Farkas, Imre Balásházy, Piroska Szabó-Révész & Rita Ambrus. (2017) Aerodynamic properties and in silico deposition of meloxicam potassium incorporated in a carrier-free DPI pulmonary system. International Journal of Pharmaceutics 520:1-2, pages 70-78.
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Lukas Pichelstorfer, Werner Hofmann, Renate Winkler-Heil, Caner U. Yurteri & John McAughey. (2016) Simulation of aerosol dynamics and deposition of combustible and electronic cigarette aerosols in the human respiratory tract. Journal of Aerosol Science 99, pages 125-132.
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A. Farkas & I. Balashazy. (2014) Development and application of a complex numerical model and software for the computation of dose conversion factors for radon progenies. Radiation Protection Dosimetry 164:3, pages 278-290.
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Hussain Majid, Khan Alam, Pierre Madl & Werner Hofmann. (2012) Exposure assessment and associated lung deposition calculations for vehicular exhaust in four metropolitan cities of Pakistan. Environmental Monitoring and Assessment 185:6, pages 5265-5276.
Crossref
Werner Hofmann. (2011) Modelling inhaled particle deposition in the human lung—A review. Journal of Aerosol Science 42:10, pages 693-724.
Crossref
Árpád Farkas, Werner Hofmann, Imre Balásházy, István Szőke, Balázs G. Madas & Mona Moustafa. (2011) Effect of site-specific bronchial radon progeny deposition on the spatial and temporal distributions of cellular responses. Radiation and Environmental Biophysics 50:2, pages 281-297.
Crossref
Werner Hofmann & Bahman Asgharian. 2011. Cardiovascular Effects of Inhaled Ultrafine and Nanosized Particles. Cardiovascular Effects of Inhaled Ultrafine and Nanosized Particles 109 124 .
. (2009) Poster Abstracts. Journal of Aerosol Medicine and Pulmonary Drug Delivery 22:2, pages 173-208.
Crossref
Árpád Farkas & Imre Balásházy. (2008) Quantification of particle deposition in asymmetrical tracheobronchial model geometry. Computers in Biology and Medicine 38:4, pages 508-518.
Crossref

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