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International Journal of Radiation Biology Volume 93, 2017 - Issue 9
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A review of radiation countermeasures focusing on injury-specific medicinals and regulatory approval status: part II. Countermeasures for limited indications, internalized radionuclides, emesis, late effects, and agents demonstrating efficacy in large animals with or without FDA IND status

Vijay K. SinghDivision of Radioprotection, Department of Pharmacology and Molecular Therapeutics, F. Edward Hébert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, USA; ;Armed Forces Radiobiology Research Institute, Uniformed Services University of the Health Sciences, Bethesda, MD, USA; Correspondence[email protected]
,
Melissa GarciaDivision of Radioprotection, Department of Pharmacology and Molecular Therapeutics, F. Edward Hébert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, USA; ;Armed Forces Radiobiology Research Institute, Uniformed Services University of the Health Sciences, Bethesda, MD, USA;
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Thomas M. SeedTech Micro Services, Bethesda, MD, USA
Pages 870-884 | Received 04 Jan 2017, Accepted 30 May 2017, Published online: 28 Jun 2017

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Vijay K. Singh, Meera Srivastava & Thomas M Seed. (2023) Protein biomarkers for radiation injury and testing of medical countermeasure efficacy: promises, pitfalls, and future directions. Expert Review of Proteomics 20:10, pages 221-246.
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Vojtěch Chmil, Alžběta Filipová & Aleš Tichý. (2023) Looking for the phoenix: the current research on radiation countermeasures. International Journal of Radiation Biology 99:8, pages 1148-1166.
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Shivani Bansal, Sunil Bansal, Brian L. Fish, Yaoxiang Li, Xiao Xu, Jose A. Fernandez, John H. Griffin, Heather A. Himburg, Marjan Boerma, Meetha Medhora & Amrita K. Cheema. (2023) Analysis of the urinary metabolic profiles in irradiated rats treated with Activated Protein C (APC), a potential mitigator of radiation toxicity. International Journal of Radiation Biology 99:7, pages 1109-1118.
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Thomas J. MacVittie. (2023) Where are the medical countermeasures against the ARS and DEARE? A current topic relative to an animal model research platform, radiation exposure context, the acute and delayed effects of acute exposure, and the FDA animal rule. International Journal of Radiation Biology 99:7, pages 994-1008.
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Vijay K. Singh & Thomas M Seed. (2023) Development of gamma-tocotrienol as a radiation medical countermeasure for the acute radiation syndrome: current status and future perspectives. Expert Opinion on Investigational Drugs 32:1, pages 25-35.
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Hillard M Lazarus, John McManus & Robert Peter Gale. (2022) Sargramostim in acute radiation syndrome. Expert Opinion on Biological Therapy 22:11, pages 1345-1352.
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Vijay K. Singh, Oluseyi O. Fatanmi, Stephen Y. Wise, Alana Carpenter, Sara Nakamura-Peek, Artur A. Serebrenik & Michael D. Kaytor. (2022) A novel oral formulation of BIO 300 confers prophylactic radioprotection from acute radiation syndrome in mice. International Journal of Radiation Biology 98:5, pages 958-967.
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Lisa S. Carnell. (2021) Spaceflight medical countermeasures: a strategic approach for mitigating effects from solar particle events. International Journal of Radiation Biology 97:sup1, pages S125-S131.
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Vijay K. Singh & Thomas M Seed. (2020) BIO 300: a promising radiation countermeasure under advanced development for acute radiation syndrome and the delayed effects of acute radiation exposure. Expert Opinion on Investigational Drugs 29:5, pages 429-441.
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Vijay K. Singh & Thomas M Seed. (2020) Pharmacological management of ionizing radiation injuries: current and prospective agents and targeted organ systems. Expert Opinion on Pharmacotherapy 21:3, pages 317-337.
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N. Yeddanapudi, M. A. Clay, D. P. Durham, C. M. Hoffman, M. J. Homer & J. M. Appler. (2020) Informing CONOPS and medical countermeasure deployment strategies after an improvised nuclear device detonation: the importance of delayed treatment efficacy data. International Journal of Radiation Biology 96:1, pages 4-11.
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Vijay K. Singh & Thomas M. Seed. (2019) The efficacy and safety of amifostine for the acute radiation syndrome. Expert Opinion on Drug Safety 18:11, pages 1077-1090.
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Angela M. Groves & Jacqueline P. Williams. (2019) Saving normal tissues – a goal for the ages. International Journal of Radiation Biology 95:7, pages 920-935.
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Vijay K. Singh, Madison Simas & Harvey Pollard. (2018) Biomarkers for acute radiation syndrome: challenges for developing radiation countermeasures following animal rule. Expert Review of Molecular Diagnostics 18:11, pages 921-924.
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Ajaswrata Dutta, Manju Lata Gupta & Savita Verma. (2018) Podophyllotoxin and rutin in combination prevents oxidative stress mediated cell death and advances revival of mice gastrointestine following lethal radiation injury. Free Radical Research 52:1, pages 103-117.
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Alana D. Carpenter, Yaoxiang Li, Brianna L. Janocha, Stephen Y. Wise, Oluseyi O. Fatanmi, Manoj Maniar, Amrita K. Cheema & Vijay K. Singh. (2023) Analysis of the Proteomic Profile in Serum of Irradiated Nonhuman Primates Treated with Ex-Rad, a Radiation Medical Countermeasure. Journal of Proteome Research 22:4, pages 1116-1126.
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Hua Guan, Wen Zhang, Dafei Xie, Yuehua Nie, Shi Chen, Xiaoya Sun, Hongling Zhao, Xiaochang Liu, Hua Wang, Xin Huang, Chenjun Bai, Bo Huang, Pingkun Zhou & Shanshan Gao. (2023) Cytosolic Release of Mitochondrial DNA and Associated cGAS Signaling Mediates Radiation-Induced Hematopoietic Injury of Mice. International Journal of Molecular Sciences 24:4, pages 4020.
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